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Biomarkers Volume 21, 2016 - Issue 4
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Review Article

Mercapturic acids: recent advances in their determination by liquid chromatography/mass spectrometry and their use in toxicant metabolism studies and in occupational and environmental exposure studies

Patricia I. MathiasDivision of Applied Science and Technology, U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Biomonitoring and Health Assessment Branch, Robert a. Taft Laboratories, Cincinnati, OH, USA;Division of Applied Science and Technology, U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Biomonitoring and Health Assessment Branch, Robert a. Taft Laboratories, Cincinnati, OH, USACorrespondence[email protected]
&
Clayton B’hymerDivision of Applied Science and Technology, U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Biomonitoring and Health Assessment Branch, Robert a. Taft Laboratories, Cincinnati, OH, USA;Division of Applied Science and Technology, U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Biomonitoring and Health Assessment Branch, Robert a. Taft Laboratories, Cincinnati, OH, USA
Pages 293-315 | Received 08 Apr 2015, Accepted 05 Jan 2016, Published online: 22 Feb 2016

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Patrick E. Hanna & M. W. Anders. (2019) The mercapturic acid pathway. Critical Reviews in Toxicology 49:10, pages 819-929.
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Aline T. Marinho, Joana P. Miranda, Umbelina Caixas, Catarina Charneira, Clara Gonçalves-Dias, M. Matilde Marques, Emília C. Monteiro, Alexandra M. M. Antunes & Sofia A. Pereira. (2019) Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity. Drug Metabolism Reviews 51:1, pages 76-90.
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Reema Deol & P. David Josephy. (2017) Acetylation of aromatic cysteine conjugates by recombinant human N-acetyltransferase 8. Xenobiotica 47:3, pages 202-207.
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Abolfazl Moghadasi, Saeed Yousefinejad & Esmaeel Soleimani. (2023) False positives and false negatives in benzene biological monitoring. Environmental Research, pages 117836.
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Kai Nieschalke, Nick Bergau, Sönke Jessel, Albrecht Seidel, Susanne Baldermann, Monika Schreiner, Klaus Abraham, Alfonso Lampen, Bernhard H. Monien, Burkhard Kleuser, Hansruedi Glatt & Fabian Schumacher. (2023) Urinary Excretion of Mercapturic Acids of the Rodent Carcinogen Methyleugenol after a Single Meal of Basil Pesto: A Controlled Exposure Study in Humans. Chemical Research in Toxicology 36:11, pages 1753-1767.
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Vanessa Gonçalves Milagres, Maria José Nunes de Paiva, Mirna Maciel d'Auriol‐Souza, Ariane Leites Larentis, Isabele Campos Costa‐Amaral & Leiliane Coelho André. (2023) Comparison study on extraction techniques used to assess S ‐phenylmercapturic acid as low benzene exposure biomarker based on gas chromatography coupled with mass spectrometry . SEPARATION SCIENCE PLUS 6:11.
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Fang-Fang Zhao, Xiao-Li Wang, Ya-Ting Lei, Hong-Qiu Li, Zhi-Ming Li, Xiao-Xiao Hao, Wei-Wei Ma, Yong-Hui Wu & Sheng-Yuan Wang. (2023) A systematic review: on the mercaptoacid metabolites of acrylamide, N-acetyl-S-(2-carbamoylethyl)-L-cysteine. Environmental Science and Pollution Research 30:38, pages 88350-88365.
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Mohd Mubashshir Naved, Roshan Wathore, Himanshu Kumbhare, Ankit Gupta & Nitin Labhasetwar. (2023) Community kitchen tandoors (CKT)-a potential candidate for air pollution mitigation strategies?. Environmental Science and Pollution Research 30:19, pages 56317-56329.
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Bernhard H. Monien & Klaus Abraham. 2023. Biomarkers in Toxicology. Biomarkers in Toxicology 123 137 .
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Marie Roser, David Béal, Camille Eldin, Leslie Gudimard, Fanny Caffin, Fanny Gros-Désormeaux, Daniel Léonço, François Fenaille, Christophe Junot, Christophe Piérard & Thierry Douki. (2021) Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog. Analytical and Bioanalytical Chemistry 413:5, pages 1337-1351.
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Adela Jing Li, Vineet Kumar Pal & Kurunthachalam Kannan. (2021) A review of environmental occurrence, toxicity, biotransformation and biomonitoring of volatile organic compounds. Environmental Chemistry and Ecotoxicology 3, pages 91-116.
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Xinyu Chen, Wei Jia, Qiao Wang, Jianxin Han, Jun Cheng, Weijiang Zeng, Qingning Zhao, Yu Zhang & Ying Zhang. (2020) Protective effect of a dietary flavonoid-rich antioxidant from bamboo leaves against internal exposure to acrylamide and glycidamide in humans. Food & Function 11:8, pages 7000-7011.
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Gianfranco Frigerio, Rosa Mercadante, Laura Campo, Elisa Polledri, Luca Boniardi, Luca Olgiati, Pasquale Missineo & Silvia Fustinoni. (2020) Urinary biomonitoring of subjects with different smoking habits. Part I: Profiling mercapturic acids. Toxicology Letters 327, pages 48-57.
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Menglan Chen, Steven G. Carmella, Yupeng Li, Yingchun Zhao & Stephen S. Hecht. (2020) Resolution and Quantitation of Mercapturic Acids Derived from Crotonaldehyde, Methacrolein, and Methyl Vinyl Ketone in the Urine of Smokers and Nonsmokers. Chemical Research in Toxicology 33:2, pages 669-677.
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Gianfranco Frigerio, Rosa Mercadante, Elisa Polledri, Pasquale Missineo, Laura Campo & Silvia Fustinoni. (2019) An LC-MS/MS method to profile urinary mercapturic acids, metabolites of electrophilic intermediates of occupational and environmental toxicants. Journal of Chromatography B 1117, pages 66-76.
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Gonçalves-Dias, Morello, Semedo, Correia, Coelho, Monteiro, Antunes & Pereira. (2019) The mercapturomic profile of health and non-communicable diseases. High-Throughput 8:2, pages 10.
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Douglas E. Stack, John A. Conrad & Bejan Mahmud. (2018) Structural Identification and Kinetic Analysis of the in Vitro Products Formed by Reaction of Bisphenol A-3,4-quinone with N -Acetylcysteine and Glutathione . Chemical Research in Toxicology 31:2, pages 81-87.
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