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Original Article

Long-term endometrial and breast safety of a specific, standardized soy extract

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Pages 368-375 | Received 28 Sep 2009, Accepted 18 Jan 2010, Published online: 10 Apr 2010

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J. Hernandez-Elizondo, C. Monteagudo, M.A. Murcia, N. Olea, F. Olea-Serrano & M. Mariscal-Arcas. (2013) Assessment of the estrogenicity of the diet of a healthy female Spanish population based on its isoflavone content. Food Additives & Contaminants: Part A 30:4, pages 627-633.
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Susanne Andres, Klaus Abraham, Klaus Erich Appel & Alfonso Lampen. (2011) Risks and benefits of dietary isoflavones for cancer. Critical Reviews in Toxicology 41:6, pages 463-506.
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S. Hüser, S. Guth, H. G. Joost, S. T. Soukup, J. Köhrle, L. Kreienbrock, P. Diel, D. W. Lachenmeier, G. Eisenbrand, G. Vollmer, U. Nöthlings, D. Marko, A. Mally, T. Grune, L. Lehmann, P. Steinberg & S. E. Kulling. (2018) Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation. Archives of Toxicology 92:9, pages 2703-2748.
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Harini Anandhi Senthilkumar, Jimmie E. Fata & Edward J. Kennelly. (2018) Phytoestrogens: The current state of research emphasizing breast pathophysiology. Phytotherapy Research 32:9, pages 1707-1719.
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Vera van der Velpen, Pieter van ‘t Veer, M. Ariful Islam, C.J.F. ter Braak, F.X. Rolaf van Leeuwen, Lydia A. Afman, Peter C. Hollman, Evert G. Schouten & Anouk Geelen. (2016) A risk assessment-driven quantitative comparison of gene expression profiles in PBMCs and white adipose tissue of humans and rats after isoflavone supplementation. Food and Chemical Toxicology 95, pages 203-210.
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M Tijhuis, E Doets, V van der Velpen & M Vonk Noordegraaf‐Schouten. (2015) Preparatory work to support the risk assessment for peri‐ and postmenopausal women taking food supplements containing isolated isoflavones. EFSA Supporting Publications 12:10.
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D. Lee Alekel, Ulrike Genschel, Kenneth J. Koehler, Heike Hofmann, Marta D. Van Loan, Bonnie S. Beer, Laura N. Hanson, Charles T. Peterson & Mindy S. Kurzer. (2015) Soy Isoflavones for Reducing Bone Loss Study. Menopause 22:2, pages 185-197.
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Derek A. Schreihofer. 2015. Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease. Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease 385 394 .
Anne Lethaby, Jane Marjoribanks, Fredi Kronenberg, Helen Roberts, John Eden & Julie Brown. (2013) Phytoestrogens for menopausal vasomotor symptoms. Cochrane Database of Systematic Reviews 2013:12.
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Armando Delmanto, Jorge Nahas-Neto, Paulo Traiman, Gilberto Uemura, Eduardo Carvalho Pessoa & Eliana Aguiar Petri Nahas. (2013) Effects of soy isoflavones on mammographic density and breast parenchyma in postmenopausal women. Menopause 20:10, pages 1049-1054.
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Wolfgang Wuttke & Dana Seidlova-Wuttke. 2013. Evidence and Rational Based Research on Chinese Drugs. Evidence and Rational Based Research on Chinese Drugs 397 430 .
John A. Eden. (2012) Phytoestrogens for menopausal symptoms: A review. Maturitas 72:2, pages 157-159.
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Adriana Aparecida Ferraz Carbonel, Ricardo Santos Simões, Regiane Helena Barros Rabelo Santos, Maria Cândida Pinheiro Baracat, Manuel de Jesus Simões, Edmund Chada Baracat & José Maria Soares Júnior. (2011) Efeitos das isoflavonas em altas doses sobre o útero da rata. Revista da Associação Médica Brasileira 57:5, pages 534-539.
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Adriana Aparecida Ferraz Carbonel, Ricardo Santos Simões, Regiane Helena Barros Rabelo Santos, Maria Cândida Pinheiro Baracat, Manuel de Jesus Simões, Edmund Chada Baracat & José Maria Júnior. (2011) Effects of high-dose isoflavones on rat uterus. Revista da Associação Médica Brasileira (English Edition) 57:5, pages 524-529.
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Adriana Aparecida Ferraz Carbonel, Ricardo Santos Simões, Regiane Helena Barros Rabelo Santos, Maria Cândida Pinheiro Baracat, Manuel de Jesus Simões, Edmund Chada Baracat & José Maria Júnior. (2011) Effects of high-dose isoflavones on rat uterus. Revista da Associação Médica Brasileira 57:5, pages 524-529.
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