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Climacteric Volume 13, 2010 - Issue 4
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Short Review

DHEA therapy in postmenopausal women: the need to move forward beyond the lack of evidence

A. R. Genazzani Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
&
N. Pluchino Department of Reproductive Medicine and Child Development, Division of Gynecology and Obstetrics, University of Pisa, Pisa, Italy
Pages 314-316 | Received 13 Apr 2010, Accepted 08 May 2010, Published online: 16 Jun 2010

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Svetlana Dragojević Dikić, Mladenko Vasiljević, Ana Jovanović, Srdjan Dikić, Aleksandar Jurišić, Ljubomir Srbinović & Svetlana Vujović. (2020) Premature ovarian insufficiency – novel hormonal approaches in optimizing fertility. Gynecological Endocrinology 36:2, pages 162-165.
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Svetlana Vujović, Miomira Ivovic, Milina Tančić-Gajić, Ljiljana Marina, Aleksandar Ljubic, Svetlana Dragojević-Dikić & Andrea Ricardo Genazzani. (2018) Endometrium receptivity in premature ovarian insufficiency – how to improve fertility rate and predict diseases?. Gynecological Endocrinology 34:12, pages 1011-1015.
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A. R. Genazzani & N. Pluchino. (2015) DHEA replacement for postmenopausal women: have we been looking in the right direction?. Climacteric 18:5, pages 669-671.
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N. Pluchino, A. Santoro, E. Casarosa, J.-M. Wenger, A. D. Genazzani, P. Petignat & A. R. Genazzani. (2013) Advances in neurosteroids: role in clinical practice. Climacteric 16:sup1, pages 8-17.
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Anna Fenton & Nick Panay. (2013) DHEA – finding a role for this enigmatic hormone. Climacteric 16:3, pages 303-304.
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Nicola Pluchino, Andrea Giannini, Vito Cela, Anna N. Santoro, Gianluca Carnevale, Manuela Zavatti, Vittoria Di Viesti, Augusta Benelli, Andrea R. Genazzani & Paola Zanoli. (2013) Effect of DHEA therapy on sexual behavior in female rats. Gynecological Endocrinology 29:5, pages 496-502.
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A. R. Genazzani, M. Stomati, V. Valentino, N. Pluchino, E. Potì, E. Casarosa, S. Merlini, A. Giannini & M. Luisi. (2011) Effect of 1-year, low-dose DHEA therapy on climacteric symptoms and female sexuality. Climacteric 14:6, pages 661-668.
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Articles from other publishers (21)

Hilde LöfqvistHilde Löfqvist. 2022. Modern Menopausal Hormone Treatment. Modern Menopausal Hormone Treatment 27 45 .
Siwei ZhangJing ZhouLijuan LiXinyao PanJing LinChuyu LiWing Ting LeungLing Wang. (2021) Effect of dehydroepiandrosterone on atherosclerosis in postmenopausal women. BioScience Trends 15:6, pages 353-364.
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Hilde LöfqvistHilde Löfqvist. 2021. Hormontherapie in den Wechseljahren. Hormontherapie in den Wechseljahren 27 45 .
Selva L Luna, Donald I Brown, Steven G Kohama & Henryk F Urbanski. (2020) Lack of effect of short-term DHEA supplementation on the perimenopausal ovary†. Biology of Reproduction 103:6, pages 1209-1216.
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Nadezhda D. Goncharova & Tamara E. Oganyan. (2018) Age-related differences in stress responsiveness of the hypothalamic-pituitary-adrenal axis of nonhuman primates with various types of adaptive behavior. General and Comparative Endocrinology 258, pages 163-172.
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Fernand Labrie. 2018. Pre-Menopause, Menopause and Beyond. Pre-Menopause, Menopause and Beyond 269 284 .
Céline Bouchard, Fernand Labrie, Leonard Derogatis, Ginette Girard, Normand Ayotte, John Gallagher, Leonello Cusan, David F. Archer, David Portman, Lyne Lavoie, Adam Beauregard, Isabelle Côté, Céline Martel, Mario Vaillancourt, John Balser, Erick Moyneur & other participating Members of the VVA Prasterone Group. (2016) Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study. Hormone Molecular Biology and Clinical Investigation 25:3, pages 181-190.
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Fernand Labrie, Leonard Derogatis, David F. Archer, William Koltun, Andrée Vachon, Douglas Young, Louise Frenette, David Portman, Marlene Montesino, Isabelle Côté, Julie Parent, Lyne Lavoie, Adam Beauregard, Céline Martel, Mario Vaillancourt, John Balser & Érick Moyneur. (2015) Effect of Intravaginal Prasterone on Sexual Dysfunction in Postmenopausal Women with Vulvovaginal Atrophy. The Journal of Sexual Medicine 12:12, pages 2401-2412.
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Nadezhda D. Goncharova, Victor Yu. Marenin & Tamara E. Oganyan. (2015) Individual Differences in Stress Responsiveness of the Hypothalamic-Pituitary-Adrenal Axis and Its Vasopressinergic Regulation in Old Monkeys. Journal of Behavioral and Brain Science 05:07, pages 280-294.
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Fernand Labrie, David Archer, Céline Bouchard, Michel Fortier, Leonello Cusan, José‐Luis Gomez, Ginette Girard, Mira Baron, Normand Ayotte, Michèle Moreau, Robert Dubé, Isabelle Côté, Claude Labrie, Lyne Lavoie, Lucy Gilbert, Céline Martel & John Balser. (2014) Lack of Influence of Dyspareunia on the Beneficial Effect of Intravaginal Prasterone (Dehydroepiandrosterone, DHEA) on Sexual Dysfunction in Postmenopausal Women. The Journal of Sexual Medicine 11:7, pages 1766-1785.
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Vieri Boncinelli, Diana Daino, Daniela Gaci Scaletti, Andrea Riccardo Genazzani & Chiara Nanini. (2013) Dall'esperienza clinica una proposta di classificazione delle fantasie sessuali. RIVISTA DI SESSUOLOGIA CLINICA:2, pages 73-79.
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Yuankui Cao, Shaofen Zhang, Shien Zou & Xian Xia. (2013) The Relationship between Endogenous Androgens and Body Fat Distribution in Early and Late Postmenopausal Women. PLoS ONE 8:3, pages e58448.
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V. Boncinelli, D. Gaci Scaletti, C. Nanini, D. Daino & A.-R. Genazzani. (2013) Fantasmes sexuels et désir hypoactif féminin. Sexologies 22:1, pages 19-23.
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V. Boncinelli, D. Gaci Scaletti, C. Nanini, D. Daino & A.R. Genazzani. (2013) Sexual fantasies and female hypoactive desire. Sexologies 22:1, pages e16-e19.
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Anna-Maria Curatola, Kui Huang & Frederick Naftolin. (2012) Dehydroepiandrosterone (DHEA) Inhibition of Monocyte Binding by Vascular Endothelium Is Associated With Sialylation of Neural Cell Adhesion Molecule. Reproductive Sciences 19:1, pages 86-91.
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M.S. Ritsner. (2011) The clinical and therapeutic potentials of dehydroepiandrosterone and pregnenolone in schizophrenia. Neuroscience 191, pages 91-100.
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Alessandro Genazzani & Chiara Lanzoni. 2011. DHEA in Human Health and Aging. DHEA in Human Health and Aging 9 34 .
. (2011) Current World Literature. Current Opinion in Endocrinology, Diabetes & Obesity 18:3, pages 231-234.
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Clarence N. Ahlem, Steven K. White, Theodore M. Page & James M. Frincke. (2011) Differential metabolism of androst-5-ene-3β,17β-diol between rats, canines, monkeys and humans. Steroids 76:7, pages 669-674.
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Andrea Riccardo Genazzani, Fiorella Bucci, Natalia Russo, Diana Daino, Anna Natalizia Santoro & Nicola Pluchino. (2011) Neurosteroids in clinical practice: implications for women’s health. Hormone Molecular Biology and Clinical Investigation 7:3.
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James K. Pru. (2011) A spectrum of serum dehydroepiandrosterone and sex steroid levels in postmenopausal women. Menopause 18:1, pages 11-12.
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