Advanced search
Publication Cover
Journal of Enzyme Inhibition and Medicinal Chemistry Volume 26, 2011 - Issue 4
Submit an article Journal homepage
1,270
Views
18
CrossRef citations to date
0
Altmetric
Original Article

Design, synthesis, and biological activity of thiazole derivatives as novel influenza neuraminidase inhibitors

Yu LiuDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China
,
Lei ZhangDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China
,
Jianzhi GongDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China
,
Hao FangDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China
,
Ailin LiuInstitute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China
,
Guanhua DuInstitute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China
&
Wenfang XuDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, ChinaCorrespondence[email protected]
 show all
Pages 506-513 | Received 06 May 2010, Accepted 19 Oct 2010, Published online: 14 Dec 2010

Citations (18)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Samir S. Kandil, Naeema H.M. Yarkandi & Suhair M.S. Jambi. (2014) Coordination of cobalt(III), nickel(II), copper(II), palladium(II) and platinum(II) with N-ethyl-N′-(4′-methylthiazol-2′-yl)thiourea (HL). Journal of Sulfur Chemistry 35:1, pages 98-105.
Read now

Articles from other publishers (17)

Mustapha Abdullahi, Adamu Uzairu, Gideon Adamu Shallangwa, Paul Andrew Mamza, Muhammad Tukur Ibrahim, Anshuman Chandra & Vijay Kumar Goel. (2023) Unveiling 1,3-Thiazine Derivative as a Potential Neuraminidase Inhibitor: Molecular Docking, Molecular Dynamics, ADMET and DFT Studies. Chemistry Africa 6:6, pages 2957-2967.
Crossref
Yu-Yang Liu, Yang-Jie Yi, Jiao Ye & Ai-Xi Hu. (2023) Design, synthesis and neuraminidase inhibitory activity of 4-methyl-5-(3-phenylacryloyl) thiazoles. Molecular Diversity.
Crossref
Kang Ning, Anuradha Roy, Fang Cheng, Peng Xu, Steve Kleiboeker, Carlos R. Escalante, Jingxin Wang & Jianming Qiu. (2022) High-Throughput Screening Identifies Inhibitors for Parvovirus B19 Infection of Human Erythroid Progenitors. Journal of Virology 96:2.
Crossref
Zhi Jian Zhong, Li Ping Cheng, Wan Pang, Xue Song Zheng & Shi Kai Fu. (2021) Design, synthesis and biological evaluation of dihydrofurocoumarin derivatives as potent neuraminidase inhibitors. Bioorganic & Medicinal Chemistry Letters 37, pages 127839.
Crossref
Mengwu Xiao, Lvjie Xu, Ding Lin, Wenwen Lian, Manying Cui, Meng Zhang, Xiaowei Yan, Shuishi Li, Jun Zhao, Jiao Ye, Ailin Liu & Aixi Hu. (2021) Design, synthesis, and bioassay of 4-thiazolinone derivatives as influenza neuraminidase inhibitors. European Journal of Medicinal Chemistry 213, pages 113161.
Crossref
Abdel Haleem M. Hussein, Ahmed A. Khames, Abu-Bakr A. El-Adasy, Ahmed A. Atalla, Mohamed Abdel-Rady, Mohamed I. A. Hassan, Mahrous A. Abou-Salim, Yaseen A. M. M. Elshaier & Assem Barakat. (2021) Multifunctional Isosteric Pyridine Analogs-Based 2-Aminothiazole: Design, Synthesis, and Potential Phosphodiesterase-5 Inhibitory Activity. Molecules 26:4, pages 902.
Crossref
Panupong Mahalapbutr, Mattanun Sangkhawasi, Jirayu Kammarabutr, Supakarn Chamni & Thanyada Rungrotmongkol. (2020) Rosmarinic Acid as a Potent Influenza Neuraminidase Inhibitor: In Vitro and In Silico Study. Current Topics in Medicinal Chemistry 20:23, pages 2046-2055.
Crossref
Ling Liu, Jiao Ye, Mengwu Xiao, Keyang Yuan, Mei He, Aixi Hu, Hao Jia & Ailin Liu. (2019) Synthesis of Novel 1,2,4‐Triazole‐3‐thione Derivatives as Influenza Neuraminidase Inhibitors. Journal of Heterocyclic Chemistry 56:8, pages 2192-2201.
Crossref
Man-Ying Cui, Jian-Xia Nie, Zhong-Zhong Yan, Meng-Wu Xiao, Ding Lin, Jiao Ye & Ai-Xi Hu. (2019) Design, synthesis, bioactivity, and DFT calculation of 2-thiazolyl-hydrazone derivatives as influenza neuraminidase inhibitors. Medicinal Chemistry Research 28:7, pages 938-947.
Crossref
Gülhan Turan-Zitouni, Leyla Yurttaş, Aouatef Tabbi, Gülşen Akalın Çiftçi, Halide Temel & Zafer Kaplancıklı. (2018) New Thiazoline-Tetralin Derivatives and Biological Activity Evaluation. Molecules 23:1, pages 135.
Crossref
Yilin Fang, Mengwu Xiao, Aixi Hu, Jiao Ye, Wenwen Lian & Ailin Liu. (2016) Design, Synthesis, and Evaluation of 3-((4-( t -Butyl)-2-(2-benzylidenehydrazinyl)thiazol-5-yl)methyl)quinolin-2(1 H )-ones as Neuraminidase Inhibitors . Chinese Journal of Chemistry 34:4, pages 403-411.
Crossref
Zhilin Wu, Junmei Peng, Aixi Hu, Jiao Ye & Guoxi Li. (2015) Design, synthesis and neuraminidase inhibitory activity of N-(5-benzyl-4-(tert-butyl)thiazol-2-yl)benzamides. Medicinal Chemistry Research 25:2, pages 356-368.
Crossref
Abdel-Zaher Abdel-Aziz Elassar. (2015) An unexpected tandem cycloaddition reaction of α,β-unsaturated acid chloride with amines: Synthesis of dihydropyrancarboxamide derivatives and biological activity. European Journal of Chemistry 6:4, pages 387-393.
Crossref
Chao Li, Jian-Song Fang, Wen-Wen Lian, Xiao-Cong Pang, Ai-Lin Liu & Guan-Hua Du. (2015) In vitro Antiviral Effects and 3D QSAR Study of Resveratrol Derivatives as Potent Inhibitors of Influenza H1N1 Neuraminidase . Chemical Biology & Drug Design 85:4, pages 427-438.
Crossref
Nadia H. Metwally, Fathy M. Abdelrazek & Mohammed T. Jaafar. (2015) Synthesis and Antimicrobial Activity of Some Novel Substituted Bis-Pyridone, Pyrazole, and Thiazole Derivatives. Journal of Heterocyclic Chemistry 52:2, pages 358-365.
Crossref
Wan Li, Lin Xia, Aixi Hu, Ailin Liu, Junmei Peng & Weiqing Tan. (2013) Design and Synthesis of 4-Alkyl-2-amino(acetamino)-6-aryl-1,3-thiazine Derivatives as Influenza Neuraminidase Inhibitors. Archiv der Pharmazie 346:9, pages 635-644.
Crossref
Tapan Karmakar, Yuting Kuang, Nouri Neamati & Jubaraj B. Baruah. (2013) Cadmium complexes and cocrystals of indium complexes of benzothiazole derivatives and anticancer activities of the cadmium complexes. Polyhedron 54, pages 285-293.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.