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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 27, 2012 - Issue 5
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Research Article

Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework

Beata KolesinskaInstitute of Organic Chemistry, Technical University of Lodz, Poland
,
Konrad BarszczInstitute of Organic Chemistry, Technical University of Lodz, Poland
,
Zbigniew J. KaminskiInstitute of Organic Chemistry, Technical University of Lodz, PolandCorrespondence[email protected]
,
Danuta DrozdowskaDepartment of Organic Chemistry, Medical University, Bialystok, Poland
,
Joanna WietrzykLudwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Science, Wroclaw, Poland
&
Marta SwitalskaLudwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Science, Wroclaw, Poland
Pages 619-627 | Received 27 May 2011, Accepted 05 Jul 2011, Published online: 08 Sep 2011

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Ziya Erdem Koc & Ahmet Uysal. (2016) Investigation of novel monopodal and dipodal oxy-Schiff base triazine from cyanuric chloride: Structural and antimicrobial studies. Journal of Macromolecular Science, Part A 53:2, pages 111-115.
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Sébastien Fortin & Gervais Bérubé. (2013) Advances in the development of hybrid anticancer drugs. Expert Opinion on Drug Discovery 8:8, pages 1029-1047.
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Articles from other publishers (15)

Pauline Adler, Marion Gras & Michael Smietana. (2023) Catalytic and Sustainable Amide Bond Formation using a DABCO/Dichlorotriazine System. ChemCatChem 15:10.
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Ankit Kumar Singh, Adarsh Kumar, Harshwardhan Singh, Pankaj Sonawane, Harshali Paliwal, Suresh Thareja, Prateek Pathak, Maria Grishina, Mariusz Jaremko, Abdul-Hamid Emwas, Jagat Pal Yadav, Amita Verma, Habibullah Khalilullah & Pradeep Kumar. (2022) Concept of Hybrid Drugs and Recent Advancements in Anticancer Hybrids. Pharmaceuticals 15:9, pages 1071.
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Dawid Maliszewski, Agnieszka Wróbel, Beata Kolesińska, Justyna Frączyk & Danuta Drozdowska. (2021) 1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors. Molecules 26:13, pages 3942.
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Hadeer M. Diab, Mostafa E. Salem, Ismail A. Abdelhamid & Ahmed H. M. Elwahy. (2020) Synthesis of novel star-shaped molecules based on a 1,3,5-triazine core linked to different heterocyclic systems as novel hybrid molecules. RSC Advances 10:72, pages 44066-44078.
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Parteek Prasher, Mousmee Sharma, Alaa A. A. Aljabali, Gaurav Gupta, Poonam Negi, Deepak N. Kapoor, Inderbir Singh, Flavia C. Zacconi, Terezinha Jesus Andreoli Pinto, Mateus Webba Silva, Hamid A. Bakshi, Dinesh Kumar Chellappan, Murtaza M. Tambuwala & Kamal Dua. (2020) Hybrid molecules based on 1,3,5‐triazine as potential therapeutics: A focused review. Drug Development Research 81:7, pages 837-858.
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Agnieszka Wróbel, Beata Kolesińska, Justyna Frączyk, Zbigniew J. Kamiński, Anna Tankiewicz-Kwedlo, Justyna Hermanowicz, Robert Czarnomysy, Dawid Maliszewski & Danuta Drozdowska. (2019) Synthesis and cellular effects of novel 1,3,5-triazine derivatives in DLD and Ht-29 human colon cancer cell lines. Investigational New Drugs 38:4, pages 990-1002.
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Azim Ziyaei Halimehjani & Elham Badali. (2019) DABCO bond cleavage for the synthesis of piperazine derivatives. RSC Advances 9:62, pages 36386-36409.
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Andreas S. Kalogirou & Panayiotis A. Koutentis. (2019) Reactions of Polychlorinated Pyrimidines with DABCO. Molbank 2019:4, pages M1084.
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Rafał Krętowski, Danuta Drozdowska, Beata Kolesińska, Zbigniew Kamiński, Justyna Frączyk & Marzanna Cechowska-Pasko. (2019) The cellular effects of novel triazine nitrogen mustards in glioblastoma LBC3, LN-18 and LN-229 cell lines. Investigational New Drugs 37:5, pages 984-993.
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Han-Qing Wu, Kai Yang, Xiao-Yun Chen, Mani Arulkumar, Neng Wang, Si-Hong Chen & Zhao-Yang Wang. (2019) A 3,4-dihalo-2(5 H )-furanone initiated ring-opening reaction of DABCO in the absence of a metal catalyst and additive and its application in a one-pot two-step reaction . Green Chemistry 21:14, pages 3782-3788.
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Yiming Chen, Yuping Jia, Weiguo Song & Lei Zhang. (2018) Therapeutic Potential of Nitrogen Mustard Based Hybrid Molecules. Frontiers in Pharmacology 9.
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Andrzej Bak, Violetta Kozik, Malgorzata Walczak, Justyna Fraczyk, Zbigniew Kaminski, Beata Kolesinska, Adam Smolinski & Josef Jampilek. (2018) Towards Intelligent Drug Design System: Application of Artificial Dipeptide Receptor Library in QSAR-Oriented Studies. Molecules 23:8, pages 1964.
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Guohui Sun, Tengjiao Fan, Lijiao Zhao, Yue Zhou & Rugang Zhong. (2017) The potential of combi-molecules with DNA-damaging function as anticancer agents. Future Medicinal Chemistry 9:4, pages 403-435.
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Maria Koyioni, Maria Manoli & Panayiotis A. Koutentis. (2015) The Reaction of DABCO with 4-Chloro-5 H -1,2,3-dithiazoles: Synthesis and Chemistry of 4-[ N -(2-Chloroethyl)piperazin-1-yl]-5 H -1,2,3-dithiazoles . The Journal of Organic Chemistry 81:2, pages 615-631.
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R. Shanmugakala, P. Tharmaraj & C.D. Sheela. (2014) Synthesis and spectral studies on metal complexes of s-triazine based ligand and non linear optical properties. Journal of Molecular Structure 1076, pages 606-613.
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