Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 5 (2012)

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Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 5 (2012)

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Research Article

Article
Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework
Beata Kolesinska, Konrad Barszcz, Zbigniew J. Kaminski, Danuta Drozdowska, Joanna Wietrzyk & Marta Switalska
Pages: 619-627
Published online: 08 Sep 2011
AbstractforSynthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework | Full Text | References | PDF (756.9 KB)
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Article
Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity
Shenghui Yu, Linna Zhang, Shifeng Yan, Peng Wang, Tino Sanchez, Frauke Christ, Zeger Debyser, Nouri Neamati & Guisen Zhao
Pages: 628-640
Published online: 11 Jan 2012
AbstractforNitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity | Full Text | References | PDF (1,012.3 KB)
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Article
Effects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: an in vitro study
Murat Cankaya, Mehmet Aktas, Mehmet Kuzucu, İlhami Gül & T. Abdulkadir Coban
Pages: 641-645
Published online: 18 Aug 2011
AbstractforEffects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: an in vitro study | Full Text | References | PDF (629.4 KB)
  • 477 Views
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Article
Pistagremic acid a new leishmanicidal triterpene isolated from Pistacia integerrima Stewart
Ghias Uddin, Abdur Rauf, Mohammad Arfan, Waliullah, Inamullah khan, Mumtaz Ali, Mazhar Taimur, Inaayat ur-Rehman & Samiullah
Pages: 646-648
Published online: 18 Aug 2011
AbstractforPistagremic acid a new leishmanicidal triterpene isolated from Pistacia integerrima Stewart | Full Text | References | PDF (624.6 KB)
  • 965 Views
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Article
Structural analysis of structurally diverse α-glucosidase inhibitors for active site feature analysis
N. S. Hari Narayana Moorthy, Maria J. Ramos & Pedro A. Fernandes
Pages: 649-657
Published online: 08 Sep 2011
AbstractforStructural analysis of structurally diverse α-glucosidase inhibitors for active site feature analysis | Full Text | References | PDF (1,015.3 KB) | Supplemental
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Article
Syntheses and evaluation of anti-inflammatory, analgesic and ulcerogenic activities of 1,3,4-oxadiazole and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole derivatives
Gita Chawla, Umesh Kumar, Sandhya Bawa & Jagdish Kumar
Pages: 658-665
Published online: 08 Sep 2011
AbstractforSyntheses and evaluation of anti-inflammatory, analgesic and ulcerogenic activities of 1,3,4-oxadiazole and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole derivatives | Full Text | References | PDF (669.7 KB)
  • 1506 Views
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Article
QSARs on human carbonic anhydrase VA and VB inhibitors of some new not yet synthesized, substituted aromatic/heterocyclic sulphonamides as anti-obesity agent
Shalini Singh & Claudiu T. Supuran
Pages: 666-672
Published online: 08 Sep 2011
AbstractforQSARs on human carbonic anhydrase VA and VB inhibitors of some new not yet synthesized, substituted aromatic/heterocyclic sulphonamides as anti-obesity agent | Full Text | References | PDF (950.8 KB)
  • 656 Views
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Article
Anti-cancer characteristics of mevinolin against three different solid tumor cell lines was not solely p53-dependent
Ali Mokhtar Mahmoud, Ahmed M. Al-Abd, David A. Lightfoot & Hany A. El-Shemy
Pages: 673-679
Published online: 02 Sep 2011
AbstractforAnti-cancer characteristics of mevinolin against three different solid tumor cell lines was not solely p53-dependent | Full Text | References | PDF (731.6 KB)
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Article
In vitro and in vivo effects of some benzodiazepine drugs on human and rabbit erythrocyte carbonic anhydrase enzymes
Murat Şentürk, Hacı Ahmet Alıcı, Şükrü Beydemir & Ömer İrfan Küfrevioglu
Pages: 680-684
Published online: 15 Sep 2011
AbstractforIn vitro and in vivo effects of some benzodiazepine drugs on human and rabbit erythrocyte carbonic anhydrase enzymes | Full Text | References | PDF (673.4 KB)
  • 651 Views
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Article
Molecular docking studies of anti-apoptotic BCL-2, BCL-XL, and MCL-1 proteins with ginsenosides from Panax ginseng
Natarajan Sathishkumar, Subramaniyam Sathiyamoorthy, Mathiyalagan Ramya, Dong-Uk Yang, Hee Nyeong Lee & Deok-Chun Yang
Pages: 685-692
Published online: 15 Sep 2011
AbstractforMolecular docking studies of anti-apoptotic BCL-2, BCL-XL, and MCL-1 proteins with ginsenosides from Panax ginseng | Full Text | References | PDF (1 MB) | Supplemental
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Article
Designing hypothesis of substituted benzoxazinones as HIV-1 reverse transcriptase inhibitors: QSAR approach
Ravichandran Veerasamy, Dinesh Kumar Subramaniam, Ooi Chia Chean & Ng Mei Ying
Pages: 693-707
Published online: 01 Oct 2011
AbstractforDesigning hypothesis of substituted benzoxazinones as HIV-1 reverse transcriptase inhibitors: QSAR approach | Full Text | References | PDF (1 MB)
  • 661 Views
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Article
Synthesis and biological evaluation of novel N, N′-disubstituted urea and thiourea derivatives as potential anti-melanoma agents
Qing-Shan Li, Peng-Cheng Lv, Huan-Qiu Li, Xiang Lu, Zi-Lin Li, Ban-Feng Ruan & Hai-Liang Zhu
Pages: 708-714
Published online: 10 Oct 2011
AbstractforSynthesis and biological evaluation of novel N, N′-disubstituted urea and thiourea derivatives as potential anti-melanoma agents | Full Text | References | PDF (673.8 KB)
  • 782 Views
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Article
Ionic derivatives of betulinic acid as novel HIV-1 protease inhibitors
Hua Zhao, Shaletha S. Holmes, Gary A. Baker, Suresh Challa, Himangshu S. Bose & Zhiyan Song
Pages: 715-721
Published online: 10 Oct 2011
AbstractforIonic derivatives of betulinic acid as novel HIV-1 protease inhibitors | Full Text | References | PDF (736 KB)
  • 1088 Views
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Article
In vitro efficacy of some cattle drugs on bovine serum paraoxonase 1 (PON1) activity
Mikail Arslan, Nahit Gencer, Oktay Arslan & Ozen Ozensoy Guler
Pages: 722-729
Published online: 10 Oct 2011
AbstractforIn vitro efficacy of some cattle drugs on bovine serum paraoxonase 1 (PON1) activity | Full Text | References | PDF (940.6 KB)
  • 917 Views
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Article
Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors
Elena Cichero, Olga Bruno & Paola Fossa
Pages: 730-743
Published online: 21 Oct 2011
AbstractforDocking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors | Full Text | References | PDF (2.3 MB)
  • 662 Views
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Article
Chromone containing sulfonamides as potent carbonic anhydrase inhibitors
Deniz Ekinci, Mariya al-Rashida, Ghulam Abbas, Murat Şentürk & Claudiu T. Supuran
Pages: 744-747
Published online: 10 Oct 2011
AbstractforChromone containing sulfonamides as potent carbonic anhydrase inhibitors | Full Text | References | PDF (601.1 KB)
  • 856 Views
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Short Communication

Studies on synthetic and structural characterization of new fluorine substituted phthalides of pharmaceutical interest
Tanu Chamoli, M. S. M. Rawat & Melissa Jacob
Pages: 748-757
Published online: 15 Sep 2011
AbstractforStudies on synthetic and structural characterization of new fluorine substituted phthalides of pharmaceutical interest | Full Text | References | PDF (729.4 KB)
  • 1034 Views
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Retraction

Retraction
Retraction
Page: 758
Published online: 10 Sep 2012
CitationforRetraction | Full Text | PDF (531.6 KB) | Supplemental
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