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Research Article

Virtual screening of low molecular weight mushrooms compounds as potential Mdm2 inhibitors

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Pages 569-575 | Received 04 Jan 2012, Accepted 16 Jan 2012, Published online: 01 Mar 2012

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Prosper Obed Chukwuemeka, Haruna Isiyaku Umar, Opeyemi Iwaloye, Oluwaseyi Matthew Oretade, Christopher Busayo Olowosoke, Michael Omoniyi Elabiyi, Festus Omotere Igbe, Oyeyemi Janet Oretade, Joy Oseme Eigbe & Funmilayo Janet Adeojo. (2022) Targeting p53-MDM2 interactions to identify small molecule inhibitors for cancer therapy: beyond “Failure to rescue”. Journal of Biomolecular Structure and Dynamics 40:19, pages 9158-9176.
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Articles from other publishers (10)

Yi Jia, Yan Li, Hai Shang, Yun Luo & Yu Tian. (2023) Ganoderic Acid A and Its Amide Derivatives as Potential Anti-Cancer Agents by Regulating the p53-MDM2 Pathway: Synthesis and Biological Evaluation. Molecules 28:5, pages 2374.
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Vladimir N. Zhabinskii, Pavel Drasar & Vladimir A. Khripach. (2022) Structure and Biological Activity of Ergostane-Type Steroids from Fungi. Molecules 27:7, pages 2103.
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Magdalena Staszczak. (2021) Fungal Secondary Metabolites as Inhibitors of the Ubiquitin–Proteasome System. International Journal of Molecular Sciences 22:24, pages 13309.
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Sarah Tomas-Hernandez, Jordi Blanco, Santiago Garcia-Vallvé, Gerard Pujadas, María José Ojeda-Montes, Aleix Gimeno, Lluís Arola, Luisa Minghetti, Raúl Beltrán-Debón & Miquel Mulero. (2021) Anti-Inflammatory and Immunomodulatory Effects of the Grifola frondosa Natural Compound o-Orsellinaldehyde on LPS-Challenged Murine Primary Glial Cells. Roles of NF-κβ and MAPK. Pharmaceutics 13:6, pages 806.
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Anja Schüffler. 2018. Physiology and Genetics. Physiology and Genetics 231 275 .
Agostinho Lemos, Mariana Leão, Joana Soares, Andreia Palmeira, Madalena Pinto, Lucília Saraiva & Maria Emília Sousa. (2016) Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction. Medicinal Research Reviews 36:5, pages 789-844.
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Wilfried Hess, Mukram M. Mackeen & Holger B. Kramer. 2016. 207 242 .
Debajit Borah, Dhrubajyoti Gogoi & R. N. S. Yadav. (2015) Computer Aided Screening, Docking and ADME Study of Mushroom Derived Compounds as Mdm2 Inhibitor, a Novel Approach. National Academy Science Letters 38:6, pages 469-473.
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Karen S. Bishop, Chi H.J. Kao, Yuanye Xu, Marcus P. Glucina, R. Russell M. Paterson & Lynnette R. Ferguson. (2015) From 2000years of Ganoderma lucidum to recent developments in nutraceuticals. Phytochemistry 114, pages 56-65.
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Tracy L. Nero, Craig J. Morton, Jessica K. Holien, Jerome Wielens & Michael W. Parker. (2014) Oncogenic protein interfaces: small molecules, big challenges. Nature Reviews Cancer 14:4, pages 248-262.
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