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Research Article

Synthesis of some novel heterocylic compounds derived from 2-[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol-4-yl]acetohydrazide and investigation of their lipase and α-glucosidase inhibition

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Pages 1002-1009 | Received 06 Jul 2014, Accepted 10 Dec 2014, Published online: 02 Feb 2015

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Yakup Kolcuoglu, Olcay Bekircan, Hilal Fazli, Emine Sahin, Aslı Ture, Atilla Akdemir & Senay Hamarat Sanlier. (2023) Design and synthesis of new heterocyclic compounds containing 5-[(1H-1,2,4-triazol-1-yl)methyl]-3H-1,2,4-triazole-3-thione structure as potent hEGFR inhibitors. Journal of Biomolecular Structure and Dynamics 41:22, pages 12753-12767.
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Elif Ayazoglu Demir, Ahmet Colak, Aylin Kalfa, Ahmet Yasar, Olcay Bekircan & Melike Yildirim Akatin. (2019) Investigation of tyrosinase inhibition by some 1,2,4 triazole derivative compounds: in vitro and in silico mechanisms. Turkish Journal of Biochemistry 44:4, pages 473-481.
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Emre Menteşe, Gülay Akyüz, Fatih Yılmaz, Nimet Baltaş & Mustafa Emirik. (2018) Synthesis of some novel quinazolin‐4(3 H )‐one hybrid molecules as potent urease inhibitors . Archiv der Pharmazie 351:12.
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Ashwani Kumar & Shilpi Chauhan. (2018) Use of Simplified Molecular Input Line Entry System and molecular graph based descriptors in prediction and design of pancreatic lipase inhibitors. Future Medicinal Chemistry 10:13, pages 1603-1622.
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Maciej Wos, Małgorzata Miazga-Karska, Agnieszka A. Kaczor, Katarzyna Klimek, Zbigniew Karczmarzyk, Dorota Kowalczuk, Waldemar Wysocki, Grazyna Ginalska, Zofia Urbanczyk-Lipkowska, Maja Morawiak & Monika Pitucha. (2017) Novel thiosemicarbazide derivatives with 4-nitrophenyl group as multi-target drugs: α-glucosidase inhibitors with antibacterial and antiproliferative activity. Biomedicine & Pharmacotherapy 93, pages 1269-1276.
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