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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 31, 2016 - Issue 6
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Research Article

Synthesis and biological activity of ester derivatives of mycophenolic acid and acridines/acridones as potential immunosuppressive agents

Grzegorz CholewinskiDepartment of Organic Chemistry, Gdansk University of Technology, Gdansk, Poland and Correspondence[email protected]
,
Dorota Iwaszkiewicz-GrzesDepartment of Organic Chemistry, Gdansk University of Technology, Gdansk, Poland and
,
Piotr TrzonkowskiDepartment of Clinical Immunology and Transplantology, Medical University of Gdansk, Gdansk, Poland
&
Krystyna DzierzbickaDepartment of Organic Chemistry, Gdansk University of Technology, Gdansk, Poland and
Pages 974-982 | Received 14 Apr 2015, Accepted 21 Jul 2015, Published online: 24 Aug 2015

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Juliusz Maksymilian Walczak, Dorota Iwaszkiewicz-Grześ, Michalina Ziomkowska, Magdalena Śliwka-Kaszyńska, Mateusz Daśko, Piotr Trzonkowski & Grzegorz Cholewiński. (2022) Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2725-2741.
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Chetan P. Shah & Prashant S. Kharkar. (2018) Newer human inosine 5′-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 972-977.
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Articles from other publishers (10)

Tanuja T. Yadav, Maushmi S. Kumar & Mayur YC. (2023) Synthesis, cytotoxicity, and docking based analysis of acridone-N-acetamides as AKT kinase inhibitors. Chemical Papers 77:6, pages 3129-3144.
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Aparna Baliwada, Kalirajan Rajagopal, Potlapati Varakumar, Kannan Raman & Gowramma Byran. (2022) A Review on Acridines as Antiproliferative Agents. Mini-Reviews in Medicinal Chemistry 22:21, pages 2769-2798.
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Magdalena Dolna, Michał Nowacki, Oksana Danylyuk, Artur Brotons-Rufes, Albert Poater & Michał Michalak. (2022) NHC–BIAN–Cu(I)-Catalyzed Friedländer-Type Annulation of 2-Amino-3-(per)fluoroacetylpyridines with Alkynes on Water. The Journal of Organic Chemistry 87:9, pages 6115-6136.
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Narendran Annadurai & Viswanath Das. 2022. Protein Kinase Inhibitors. Protein Kinase Inhibitors 571 596 .
Agnieszka Siebert, Grzegorz Cholewiński, Piotr Trzonkowski & Janusz Rachon. (2020) Immunosuppressive properties of amino acid and peptide derivatives of mycophenolic acid. European Journal of Medicinal Chemistry 189, pages 112091.
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Maria Voura, Parvez Khan, Savvas Thysiadis, Sotiris Katsamakas, Aarfa Queen, Gulam Mustafa Hasan, Sher Ali, Vasiliki Sarli & Md. Imtaiyaz Hassan. (2019) Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones. Scientific Reports 9:1.
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Miroslawa Cichorek, Anna Ronowska, Monika Gensicka-Kowalewska, Milena Deptula, Iwona Pelikant-Malecka & Krystyna Dzierzbicka. (2018) Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma. Journal of Cancer Research and Clinical Oncology 145:1, pages 165-179.
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Chetan P. Shah & Prashant S. Kharkar. (2018) Discovery of novel human inosine 5′-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents. European Journal of Medicinal Chemistry 158, pages 286-301.
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Agnieszka Siebert, Grzegorz Cholewiński, Dorota Garwolińska, Adrian Olejnik, Janusz Rachoń & Jarosław Chojnacki. (2018) The synthesis and structure of a potential immunosuppressant: N-mycophenoyl malonic acid dimethyl ester. Journal of Molecular Structure 1151, pages 218-222.
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Dorota Iwaszkiewicz-Grzes, Grzegorz Cholewinski, Agata Kot-Wasik, Piotr Trzonkowski & Krystyna Dzierzbicka. (2017) Investigations on the immunosuppressive activity of derivatives of mycophenolic acid in immature dendritic cells. International Immunopharmacology 44, pages 137-142.
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