Citations (31)
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Koen Augustyns, Pieter Van der Veken, Kristel Senten & Achiel Haemers. (2003) Dipeptidyl peptidase IV inhibitors as new therapeutic agents for the treatment of Type 2 diabetes. Expert Opinion on Therapeutic Patents 13:4, pages 499-510.
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Anne-Marie Lambeir, Christine Durinx, Simon Scharpé & Ingrid De Meester. (2003) Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV. Critical Reviews in Clinical Laboratory Sciences 40:3, pages 209-294.
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Torsten Steinmetzer, Jerzy Silberring, Carmen Mrestani-Klaus, Siegfried Fittkau, Alfred Barth & Hans-Ulrich Demuth. (1993) Peptidyl Ammonium Methyl Ketones as Substrate Analog Inhibitors of Proline-Specific Peptidases. Journal of Enzyme Inhibition 7:2, pages 77-85.
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U. Neumann, T. Steinmetzer, A. Barth & H.-U. Demuth. (1991) Reaction of Dipeptidylpeptidase IV with Substrate-Analogous Azapeptides. Journal of Enzyme Inhibition 4:3, pages 213-226.
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Hans-Ulrich Demuth, Jerzy Silberring & Fred Nyberg. (1991) Inhibition of Proteases with Enkephalin-Analogue Inhibitors. Journal of Enzyme Inhibition 4:4, pages 289-298.
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Hans-Ulrich Demuth. (1990) Recent Developments in Inhibiting Cysteine and Serine Proteases. Journal of Enzyme Inhibition 3:4, pages 249-278.
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Articles from other publishers (25)
Dibyendu Dana & Sanjai K. Pathak. (2020) A Review of Small Molecule Inhibitors and Functional Probes of Human Cathepsin L. Molecules 25:3, pages 698.
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Jens-Uwe Peters & Patrizio Mattei. 2010. Analogue-Based Drug Discovery II. Analogue-Based Drug Discovery II
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134
.
Michael Engel, Torsten Hoffmann, Susanne Manhart, Ulrich Heiser, Sylvie Chambre, Robert Huber, Hans-Ulrich Demuth & Wolfram Bode. (2006) Rigidity and Flexibility of Dipeptidyl Peptidase IV: Crystal Structures of and Docking Experiments with DPIV. Journal of Molecular Biology 355:4, pages 768-783.
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M. Jenzsch, M. Lange, J. Bär, J.-U. Rahfeld & A. Lübbert. (2004) Bioreactor Retrofitting to Avoid Aeration with Oxygen in Pichia Pastoris Cultivation Processes for Recombinant Protein Production. Chemical Engineering Research and Design 82:9, pages 1144-1152.
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Michael Engel, Torsten Hoffmann, Leona Wagner, Michael Wermann, Ulrich Heiser, Reiner Kiefersauer, Robert Huber, Wolfram Bode, Hans-Ulrich Demuth & Hans Brandstetter. (2003) The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism. Proceedings of the National Academy of Sciences 100:9, pages 5063-5068.
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J. Bär, A. Weber, T. Hoffmann, J. Stork, M. Wermann, L. Wagner, S. Aust, B. Gerhartz & H.-U. Demuth. (2003) Characterisation of Human Dipeptidyl Peptidase IV Expressed in Pichia pastoris. A Structural and Mechanistic Comparison between the Recombinant Human and the Purified Porcine Enzyme. Biological Chemistry 384:12.
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Kake Zhao, Dong Sung Lim, Takashi Funaki & John T. Welch. (2003) Inhibition of dipeptidyl peptidase IV (DPP IV) by 2-(2-amino-1-fluoro-propylidene)-cyclopentanecarbonitrile, a fluoroolefin containing peptidomimetic. Bioorganic & Medicinal Chemistry 11:2, pages 207-215.
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Ingo Schulz, Bernd Gerhartz, Antje Neubauer, Andreas Holloschi, Ulrich Heiser, Mathias Hafner & Hans‐Ulrich Demuth. (2002) Modulation of inositol 1,4,5‐triphosphate concentration by prolyl endopeptidase inhibition. European Journal of Biochemistry 269:23, pages 5813-5820.
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Wolfgang Brandt. 2002. Cellular Peptidases in Immune Functions and Diseases 2. Cellular Peptidases in Immune Functions and Diseases 2
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Jian Lin, Paul J. Toscano & John T. Welch. (1998)
Inhibition of dipeptidyl peptidase IV by fluoroolefin-containing
N
-peptidyl-
O
-hydroxylamine peptidomimetics
. Proceedings of the National Academy of Sciences 95:24, pages 14020-14024.
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K.J.L. Augustyns, A.M. Lambeir, M Borloo, I De Meester, I Vedernikova, G Vanhoof, D Hendriks, S Scharpé & A Haemers. (1997) Pyrrolidides: synthesis and structure-activity relationship as inhibitors of dipeptidyl peptidase IV. European Journal of Medicinal Chemistry 32:4, pages 301-309.
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Hans-Ulrich Demuth, Angelika Schierhorn, Philip Bryan, Ralph Höfke, Heidrun Kirschke & Dieter Brömme. (1996) N-peptidyl, O-acyl hydroxamates: comparison of the selective inhibition of serine and cysteine proteinases. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1295:2, pages 179-186.
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A Lambeir. (1996) Dipeptide-derived diphenyl phosphonate esters: mechanism-based inhibitors of dipeptidyl peptidase IV. Biochimica et Biophysica Acta (BBA) - General Subjects 1290:1, pages 76-82.
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John T. Welch & Jian Lin. (1996) Fluoroolefin containing dipeptide isosteres as inhibitors of dipeptidyl peptidase IV(CD26). Tetrahedron 52:1, pages 291-304.
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Roger J. Snow & William W. Bachovchin. 1995.
149
177
.
Anke C. U. Steinmetz, Hans-Ulrich Demuth & Dagmar Ringe. (2002) Inactivation of Subtilisin Carlsberg by N-((tert-Butoxycarbonyl)alanylprolylphenylalanyl)-O-benzoyl Hydroxylamine: Formation of a Covalent Enzyme-Inhibitor Linkage in the Form of a Carbamate Derivative. Biochemistry 33:34, pages 10535-10544.
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Dieter Bromme & Hans-Ulrich Demuth. 1994. Proteolytic Enzymes: Serine and Cysteine Peptidases. Proteolytic Enzymes: Serine and Cysteine Peptidases
671
685
.
Martin Hegen, Hans-Willi Mittr?cker, Rosula Hug, Hans-Ulrich Demuth, Klaus Neubert, Alfred Barth & Bernhard Fleischer. (1993) Enzymatic Activity of CD26 (Dipeptidylpeptidase IV) is not Required for Its Signalling Function in T Cells. Immunobiology 189:5, pages 483-493.
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Dieter Brömme, Ulf Neumann, Heidrun Kirschke & Hans-Ulrich Demuth. (1993) Novel N-peptidyl-O-acyl hydroxamates: selective inhibitors of cysteine proteinases. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1202:2, pages 271-276.
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H.-U. Demuth, A. St?ckel, A. Schierhorn, S. Fittkau, H. Kirschke & D. Br?mme. (1993) Inhibition of aminopeptidases by N-aminoacyl-O-4-nitrobenzoyl hydroxamates. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1202:2, pages 265-270.
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Nigel M. Hooper. 1993. Biological Barriers to Protein Delivery. Biological Barriers to Protein Delivery
23
50
.
Ingrid De Meester, Greet Vanhoof, Dirk Hendriks, Hans-Ulrich Demuth, Arieh Yaron & Simon Scharp?. (1992) Characterization of dipeptidyl peptidase IV (CD26) from human lymphocytes. Clinica Chimica Acta 210:1-2, pages 23-34.
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Greet Vanhoof, Ingrid de Meester, Filip Goossens, Dirk Hendriks, Simon Scharp?Arieh Yaron. (1992) Kininase activity in human platelets: Cleavage of the Arg1-Pro2 bond of bradykinin by aminopeptidase P. Biochemical Pharmacology 44:3, pages 479-487.
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Ekkehard SCH?N, Ilona BORN, Hans-Ulrich DEMUTH, J?rgen FAUST, Klaus NEUBERT, Torsten STEINMETZER, Alfred BARTH & Siegfried ANSORGE. (1991) Dipeptidyl Peptidase IV in the Immune System. Effects of Specific Enzyme Inhibitors on Activity of Dipeptidyl Peptidase IV and Proliferation of Human Lymphocytes. Biological Chemistry Hoppe-Seyler 372:1, pages 305-312.
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Hans-Ulrich Demuth, Christoph Schönlein & Alfred Barth. (1989) Potent and selective inactivation of proteinases with N-peptidyl-O-acylhydroxylamines. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 996:1-2, pages 19-22.
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