2,622
Views
99
CrossRef citations to date
0
Altmetric
Original Article

Sterile intra-amniotic inflammation in asymptomatic patients with a sonographic short cervix: prevalence and clinical significance

, , , , , , , , , , , & show all
Pages 1343-1359 | Received 21 Jul 2014, Accepted 10 Aug 2014, Published online: 24 Sep 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (20)

Roberto Romero, Tinnakorn Chaiworapongsa, Arun Meyyazhagan, Eunjung Jung, Bo Hyun Yoon, David Kmak, Lami Yeo, Jeffrey Johnson & Chaur-Dong Hsu. (2024) Treatment of cervical insufficiency and/or a short cervix with antimicrobial agents can restore cervical length and lead to pregnancy prolongation and term delivery. The Journal of Maternal-Fetal & Neonatal Medicine 37:1.
Read now
Ondrej Soucek, Marian Kacerovsky, Ivana Kacerovska Musilova, Jaroslav Stranik, Rudolf Kukla, Radka Bolehovska & Ctirad Andrys. (2023) Amniotic fluid CD36 in pregnancies complicated by spontaneous preterm delivery: a retrospective cohort study. The Journal of Maternal-Fetal & Neonatal Medicine 36:1.
Read now
Mariachiara Bosco, Roberto Romero, Dahiana M. Gallo, Manaphat Suksai, Francesca Gotsch, Eunjung Jung, Piya Chaemsaithong, Adi L. Tarca, Nardhy Gomez-Lopez, Marcia Arenas-Hernandez, Arun Meyyazhagan, Malek Al Qasem, Massimo P. Franchi, Lawrence I. Grossman, Siddhesh Aras & Tinnakorn Chaiworapongsa. (2023) Evidence for the participation of CHCHD2/MNRR1, a mitochondrial protein, in spontaneous labor at term and in preterm labor with intra-amniotic infection. The Journal of Maternal-Fetal & Neonatal Medicine 36:1.
Read now
Sunil Jaiman, Roberto Romero, Francesca Gotsch, Swarnalata Gowrishankar, Kashif Mohiuddin, Dahiana M. Gallo, Eunjung Jung, Manaphat Suksai & Evita Fernandez. (2022) Fetal sepsis: a cause of stillbirth. The Journal of Maternal-Fetal & Neonatal Medicine 35:25, pages 9966-9970.
Read now
Ondrej Soucek, Marian Kacerovsky, Jaroslav Stranik, Ivana Musilova, Lenka Pliskova, Radka Bolehovska, Jana Matulova & Ctirad Andrys. (2022) Macrophage inflammatory protein-1α in amniotic and cervical fluids in spontaneous preterm labor with intact membranes with respect to intra-amniotic inflammation. The Journal of Maternal-Fetal & Neonatal Medicine 35:25, pages 6770-6778.
Read now
Hana Burckova, Jaroslav Stranik, Ivana Musilova, Jana Matulova, Bo Jacobsson & Marian Kacerovsky. (2022) Intra-amniotic inflammatory complications in preterm prelabor rupture of membranes and long-term neurodevelopmental outcomes of infants: a systematic review. The Journal of Maternal-Fetal & Neonatal Medicine 35:25, pages 5993-5998.
Read now
Lami Yeo, Roberto Romero, Tinnakorn Chaiworapongsa, Robert Para, Jeffrey Johnson, David Kmak, Eunjung Jung, Bo Hyun Yoon & Chaur-Dong Hsu. (2022) Resolution of acute cervical insufficiency after antibiotics in a case with amniotic fluid sludge. The Journal of Maternal-Fetal & Neonatal Medicine 35:25, pages 5416-5426.
Read now
Jaroslav Stranik, Marian Kacerovsky, Ctirad Andrys, Ondrej Soucek, Radka Bolehovska, Magdalena Holeckova, Jana Matulova, Bo Jacobsson & Ivana Musilova. (2022) Intra-amniotic infection and sterile intra-amniotic inflammation are associated with elevated concentrations of cervical fluid interleukin-6 in women with spontaneous preterm labor with intact membranes. The Journal of Maternal-Fetal & Neonatal Medicine 35:25, pages 4861-4869.
Read now
Eun Jung Jung, Roberto Romero, Nardhy Gomez-Lopez, Carmen Paredes, Ramiro Diaz-Primera, Edgar Hernandez-Andrade, Chaur-Dong Hsu & Lami Yeo. (2022) Cervical insufficiency, amniotic fluid sludge, intra-amniotic infection, and maternal bacteremia: the need for a point-of-care test to assess inflammation and bacteria in amniotic fluid. The Journal of Maternal-Fetal & Neonatal Medicine 35:24, pages 4775-4781.
Read now
Marian Kacerovsky, Magdalena Holeckova, Martin Stepan, Miroslav Gregor, Peter Vescicik, Daniel Lesko, Hana Burckova, Lenka Pliskova, Radka Bolehovska, Ctirad Andrys, Bo Jacobsson & Ivana Musilova. (2022) Amniotic fluid glucose level in PPROM pregnancies: a glance at the old friend. The Journal of Maternal-Fetal & Neonatal Medicine 35:12, pages 2247-2259.
Read now
George Schwenkel, Roberto Romero, Rebecca Slutsky, Kenichiro Motomura, Chaur-Dong Hsu & Nardhy Gomez-Lopez. (2021) HSP70: an alarmin that does not induce high rates of preterm birth but does cause adverse neonatal outcomes. The Journal of Maternal-Fetal & Neonatal Medicine 34:24, pages 4110-4118.
Read now
Hassendrini N. Peiris, Roberto Romero, Kanchan Vaswani, Sarah Reed, Nardhy Gomez-Lopez, Adi L. Tarca, Dereje W. Gudicha, Offer Erez, Eli Maymon & Murray D. Mitchell. (2021) Preterm labor is characterized by a high abundance of amniotic fluid prostaglandins in patients with intra-amniotic infection or sterile intra-amniotic inflammation. The Journal of Maternal-Fetal & Neonatal Medicine 34:24, pages 4009-4024.
Read now
Kevin R. Theis, Violetta Florova, Roberto Romero, Andrei B. Borisov, Andrew D. Winters, Jose Galaz & Nardhy Gomez-Lopez. (2021) Sneathia: an emerging pathogen in female reproductive disease and adverse perinatal outcomes. Critical Reviews in Microbiology 47:4, pages 517-542.
Read now
Nardhy Gomez-Lopez, Roberto Romero, Bogdan Panaitescu, Derek Miller, Chengrui Zou, Dereje W. Gudicha, Adi L. Tarca, Robert Para, Percy Pacora, Sonia S. Hassan & Chaur-Dong Hsu. (2021) Gasdermin D: in vivo evidence of pyroptosis in spontaneous labor at term. The Journal of Maternal-Fetal & Neonatal Medicine 34:4, pages 569-579.
Read now
Olga Pustotina. (2020) Effects of antibiotic therapy in women with the amniotic fluid “sludge” at 15–24 weeks of gestation on pregnancy outcomes. The Journal of Maternal-Fetal & Neonatal Medicine 33:17, pages 3016-3027.
Read now
Percy Pacora, Roberto Romero, Offer Erez, Eli Maymon, Bogdan Panaitescu, Juan Pedro Kusanovic, Adi L. Tarca, Chaur-Dong Hsu & Sonia S. Hassan. (2019) The diagnostic performance of the beta-glucan assay in the detection of intra-amniotic infection with Candida species. The Journal of Maternal-Fetal & Neonatal Medicine 32:10, pages 1703-1720.
Read now
Ivana Musilova, Ctirad Andrys, Marcela Drahosova, Ondrej Soucek, Radka Kutova, Lenka Pliskova, Richard Spacek, Piotr Laudanski, Bo Jacobsson & Marian Kacerovsky. (2016) Amniotic fluid calreticulin in pregnancies complicated by the preterm prelabor rupture of membranes. The Journal of Maternal-Fetal & Neonatal Medicine 29:24, pages 3921-3929.
Read now
Sun Min Kim, Roberto Romero, JoonHo Lee, Piya Chaemsaithong, Min-Woo Lee, Noppadol Chaiyasit, Hyo-Jin Lee & Bo Hyun Yoon. (2016) About one-half of early spontaneous preterm deliveries can be identified by a rapid matrix metalloproteinase-8 (MMP-8) bedside test at the time of mid-trimester genetic amniocentesis*. The Journal of Maternal-Fetal & Neonatal Medicine 29:15, pages 2414-2422.
Read now
Piya Chaemsaithong, Roberto Romero, Steven J. Korzeniewski, Alicia Martinez-Varea, Zhong Dong, Bo Hyun Yoon, Sonia S. Hassan, Tinnakorn Chaiworapongsa & Lami Yeo. (2016) A point of care test for interleukin-6 in amniotic fluid in preterm prelabor rupture of membranes: a step toward the early treatment of acute intra-amniotic inflammation/infection. The Journal of Maternal-Fetal & Neonatal Medicine 29:3, pages 360-367.
Read now
Piya Chaemsaithong, Roberto Romero, Steven J. Korzeniewski, Alicia Martinez-Varea, Zhong Dong, Bo Hyun Yoon, Sonia S. Hassan, Tinnakorn Chaiworapongsa & Lami Yeo. (2016) A rapid interleukin-6 bedside test for the identification of intra-amniotic inflammation in preterm labor with intact membranes. The Journal of Maternal-Fetal & Neonatal Medicine 29:3, pages 349-359.
Read now

Articles from other publishers (79)

Marian Kacerovsky, Helena Hornychova, Sunil Jaiman, Ladislava Pavlikova, Magdalena Holeckova, Bo Jacobsson, Panagiotis Tsiartas & Ivana Musilova. (2024) Angiogenic imbalance in pregnancies with preterm prelabor rupture of membranes between 34 and 37 weeks of gestation. Acta Obstetricia et Gynecologica Scandinavica 103:6, pages 1120-1131.
Crossref
Eunjung Jung, Roberto Romero, Manaphat Suksai, Francesca Gotsch, Piya Chaemsaithong, Offer Erez, Agustin Conde-Agudelo, Nardhy Gomez-Lopez, Stanley M. Berry, Arun Meyyazhagan & Bo Hyun Yoon. (2024) Clinical chorioamnionitis at term: definition, pathogenesis, microbiology, diagnosis, and treatment. American Journal of Obstetrics and Gynecology 230:3, pages S807-S840.
Crossref
Enrico R. Barrozo, Maxim D. Seferovic, Mark P. Hamilton, David N. Moorshead, Michael D. Jochum, Trang Do, Derek S. O’Neil, Melissa A. Suter & Kjersti M. Aagaard. (2024) Zika virus co-opts microRNA networks to persist in placental niches detected by spatial transcriptomics. American Journal of Obstetrics and Gynecology 230:2, pages 251.e1-251.e17.
Crossref
Ivana Musilova, Jaroslav Stranik, Bo Jacobsson & Marian Kacerovsky. (2024) Antibiotic treatment reduces the intensity of intraamniotic inflammation in pregnancies with idiopathic vaginal bleeding in the second trimester of pregnancy. American Journal of Obstetrics and Gynecology 230:2, pages 245.e1-245.e14.
Crossref
Valeria Garcia-Flores, Roberto Romero, Adi L. Tarca, Azam PeyvandipourYi XuJose Galaz, Derek Miller, Tinnakorn Chaiworapongsa, Piya ChaemsaithongStanley M. BerryAwoniyi O. Awonuga, David R. Bryant, Roger Pique-Regi & Nardhy Gomez-Lopez. (2024) Deciphering maternal-fetal cross-talk in the human placenta during parturition using single-cell RNA sequencing. Science Translational Medicine 16:729.
Crossref
Jose Galaz, Roberto Romero, Jonathan M. Greenberg, Kevin R. Theis, Marcia Arenas-Hernandez, Yi Xu, Marcelo Farias-Jofre, Derek Miller, Tomi Kanninen, Valeria Garcia-Flores & Nardhy Gomez-Lopez. (2023) Host-microbiome interactions in distinct subsets of preterm labor and birth. iScience 26:12, pages 108341.
Crossref
Marcelo Farias-Jofre, Roberto Romero, Jose Galaz, Yi Xu, Derek Miller, Valeria Garcia-Flores, Marcia Arenas-Hernandez, Andrew D. Winters, Bruce A. Berkowitz, Robert H. Podolsky, Yimin Shen, Tomi Kanninen, Bogdan Panaitescu, Catherine R. Glazier, Roger Pique-Regi, Kevin R. Theis & Nardhy Gomez-Lopez. (2023) Blockade of IL-6R prevents preterm birth and adverse neonatal outcomes. eBioMedicine 98, pages 104865.
Crossref
Jose Galaz, Kenichiro Motomura, Roberto Romero, Zhenjie Liu, Valeria Garcia-Flores, Li Tao, Yi Xu, Bogdan Done, Marcia Arenas-Hernandez, Tomi Kanninen, Marcelo Farias-Jofre, Derek Miller, Adi L. Tarca & Nardhy Gomez-Lopez. (2023) A key role for NLRP3 signaling in preterm labor and birth driven by the alarmin S100B. Translational Research 259, pages 46-61.
Crossref
Enrico R. Barrozo, Maxim D. Seferovic, Eumenia C.C. Castro, Angela M. Major, David N. Moorshead, Michael D. Jochum, Ricardo Ferral Rojas, Cynthia D. Shope & Kjersti M. Aagaard. (2023) SARS-CoV-2 niches in human placenta revealed by spatial transcriptomics. Med 4:9, pages 612-634.e4.
Crossref
Tomi Kanninen, Li Tao, Roberto Romero, Yi Xu, Marcia Arenas-Hernandez, Jose Galaz, Zhenjie Liu, Derek Miller, Dustyn Levenson, Jonathan M. Greenberg, Jonathan Panzer, Justin Padron, Kevin R. Theis & Nardhy Gomez-Lopez. (2023) Thymic stromal lymphopoietin participates in the host response to intra-amniotic inflammation leading to preterm labor and birth. Human Immunology 84:9, pages 450-463.
Crossref
Marian Kacerovsky, Ivana Musilova, Simona Baresova, Klara Kolarova, Jana Matulova, Johanna Wiik, Verena Sengpiel & Bo Jacobsson. (2023) Cervical excisional treatment increases the risk of intraamniotic infection in subsequent pregnancy complicated by preterm prelabor rupture of membranes. American Journal of Obstetrics and Gynecology 229:1, pages 51.e1-51.e13.
Crossref
Kanako Gondo, Fumio Yamasaki, Makoto Nomiyama, Nami Hisamoto, Natsumi Yamashita, Takuya Nakagawa, Masazumi Ikeda, Satoko Tsuda, Masato Ishimatsu, Yuko Oshima, Takeshi Ono, Yutaka Kozuma, Yukiko Nakura, Itaru Yanagihara & Keisuke Tsumura. (2023) Relationship of maternal inflammatory response and fetal inflammatory response to duration and intensity of intra-amniotic infection and inflammation. Placenta 137, pages 23-30.
Crossref
Natalia Cardozo Buitrago, Luisa Fernanda López Torres, Andrea Arias Muñoz, María Nazareth Campo Campo, Jorge Hernán Gutiérrez Marín, José Enrique Sanín Blair & Diana Paola Cuesta Castro. (2023) Desenlaces materno-perinatales en pacientes tratadas con terapia antimicrobiana por sospecha de infección inflamación intraamniótica subclínica. CES Medicina 37:1, pages 29-43.
Crossref
Maria Teresa Gervasi, Roberto Romero, Elisa Cainelli, Paola Veronese, Maria Rosa Tran, Eunjung Jung, Manaphat Suksai, Mariachiara Bosco & Francesca Gotsch. (2023) Intra-amniotic inflammation in the mid-trimester of pregnancy is a risk factor for neuropsychological disorders in childhood. Journal of Perinatal Medicine 51:3, pages 363-378.
Crossref
Anna Kornete, Ludmila Volozonoka, Maksims Zolovs, Adele Rota, Inga Kempa, Linda Gailite, Dace Rezeberga & Anna Miskova. (2023) Management of Pregnancy with Cervical Shortening: Real-Life Clinical Challenges. Medicina 59:4, pages 653.
Crossref
P. Luque González, I.M. Fontán Atalaya & J.C. Mora Palma. (2023) Uso de indometacina y antibioterapia para el manejo de cérvix corto asintomático. Clínica e Investigación en Ginecología y Obstetricia 50:1, pages 100795.
Crossref
Valeria Garcia-Flores, Roberto Romero, Azam Peyvandipour, Jose Galaz, Errile Pusod, Bogdan Panaitescu, Derek Miller, Yi Xu, Li Tao, Zhenjie Liu, Adi L. Tarca, Roger Pique-Regi & Nardhy Gomez-Lopez. (2023) A single-cell atlas of murine reproductive tissues during preterm labor. Cell Reports 42:1, pages 111846.
Crossref
Amanda Roman, Moti Gulersen, Rupsa C. Boelig & Vincenzo Berghella. (2023) Proposed staging criteria for sonographic and physical exam for cervical changes at <24 weeks gestation to predict preterm birth. American Journal of Obstetrics & Gynecology MFM 5:1, pages 100753.
Crossref
Goran AugustinGoran Augustin. 2023. Acute Abdomen During Pregnancy. Acute Abdomen During Pregnancy 75 116 .
M. Sanz Cortes, R. Corroenne, B. Johnson, H. Sangi‐Haghpeykar, G. Mandy, S. VanLoh, A. Nassr, J. Espinoza, R. Donepudi, A. A. Shamshirsaz, W. E. Whitehead & M. Belfort. (2023) Effect of preoperative low–normal cervical length on perinatal outcome after laparotomy‐assisted fetoscopic spina bifida repair. Ultrasound in Obstetrics & Gynecology 61:1, pages 74-80.
Crossref
Jose Galaz, Roberto Romero, Marcia Arenas-Hernandez, Marcelo Farias-Jofre, Kenichiro Motomura, Zhenjie Liu, Naoki Kawahara, Catherine Demery-Poulos, Tzu Ning Liu, Justin Padron, Bogdan Panaitescu & Nardhy Gomez-Lopez. (2022) Clarithromycin prevents preterm birth and neonatal mortality by dampening alarmin-induced maternal–fetal inflammation in mice. BMC Pregnancy and Childbirth 22:1.
Crossref
Piya Chaemsaithong, Waranyu Lertrut, Threebhorn Kamlungkuea, Pitak Santanirand, Arunee Singsaneh, Adithep Jaovisidha, Sasikarn Pakdeeto, Paninee Mongkolsuk & Pisut Pongchaikul. (2022) Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review. BMC Infectious Diseases 22:1.
Crossref
Kyung Joon Oh, Roberto Romero, Hyeon Ji Kim, Eunjung Jung, Francesca Gotsch, Manaphat Suksai & Bo Hyun Yoon. (2022) The role of intraamniotic inflammation in threatened midtrimester miscarriage. American Journal of Obstetrics and Gynecology 227:6, pages 895.e1-895.e13.
Crossref
Jana Matulova, Marian Kacerovsky, Radka Bolehovska, Rudolf Kukla, Pavel Bostik, Klara Kolarova, Simona Frydrychová, Bo Jacobsson & Ivana Musilova. (2022) Intra-amniotic inflammation and birth weight in pregnancies with preterm labor with intact membranes: A retrospective cohort study. Frontiers in Pediatrics 10.
Crossref
Maja Zakošek Pipan, Ožbalt Podpečan & Janko Mrkun. (2022) The fascinating microbes and their impact on neonatal dogs and cats – A review. Acta Veterinaria Hungarica 70:3, pages 175-183.
Crossref
Dereje W. Gudicha, Roberto Romero, Nardhy Gomez-Lopez, Jose Galaz, Gaurav Bhatti, Bogdan Done, Eunjung Jung, Dahiana M. Gallo, Mariachiara Bosco, Manaphat Suksai, Ramiro Diaz-Primera, Piya Chaemsaithong, Francesca Gotsch, Stanley M. Berry, Tinnakorn Chaiworapongsa & Adi L. Tarca. (2022) The amniotic fluid proteome predicts imminent preterm delivery in asymptomatic women with a short cervix. Scientific Reports 12:1.
Crossref
Derek Miller, Roberto Romero, Marian Kacerovsky, Ivana Musilova, Jose Galaz, Valeria Garcia-Flores, Yi Xu, Errile Pusod, Catherine Demery-Poulos, Pedro Gutierrez-Contreras, Tzu Ning Liu, Eunjung Jung, Kevin R. Theis, Lanetta A. Coleman & Nardhy Gomez-Lopez. (2022) Defining a role for Interferon Epsilon in normal and complicated pregnancies. Heliyon 8:7, pages e09952.
Crossref
Meyer Gershater, Roberto Romero, Marcia Arenas-Hernandez, Jose Galaz, Kenichiro Motomura, Li Tao, Yi Xu, Derek Miller, Roger Pique-Regi, Gregorio MartinezIIIIII, Yesong Liu, Eunjung Jung, Robert Para & Nardhy Gomez-Lopez. (2022) IL-22 Plays a Dual Role in the Amniotic Cavity: Tissue Injury and Host Defense against Microbes in Preterm Labor. The Journal of Immunology 208:7, pages 1595-1615.
Crossref
Marian Kacerovsky, Jaroslav Stranik, Jana Matulova, Martina Chalupska, Jan Mls, Tomáš Faist, Helena Hornychova, Rudolf Kukla, Radka Bolehovska, Pavel Bostik, Bo Jacobsson & Ivana Musilova. (2022) Clinical characteristics of colonization of the amniotic cavity in women with preterm prelabor rupture of membranes, a retrospective study. Scientific Reports 12:1.
Crossref
Andrew D. Winters, Roberto Romero, Jonathan M. Greenberg, Jose Galaz, Zachary D. Shaffer, Valeria Garcia-Flores, David J. Kracht, Nardhy Gomez-Lopez & Kevin R. Theis. (2022) Does the Amniotic Fluid of Mice Contain a Viable Microbiota?. Frontiers in Immunology 13.
Crossref
Erin E. Bolte, David Moorshead & Kjersti M. Aagaard. (2022) Maternal and early life exposures and their potential to influence development of the microbiome. Genome Medicine 14:1.
Crossref
Viral G. Jain, Kent A. Willis, Alan Jobe & Namasivayam Ambalavanan. (2021) Chorioamnionitis and neonatal outcomes. Pediatric Research 91:2, pages 289-296.
Crossref
Maria Orsaria, Stefania Liviero, Emma Rossetti, Carla Pittini, Lorenza Driul, Ambrogio P. Londero & Laura Mariuzzi. (2021) Placental acute inflammation infiltrates and pregnancy outcomes: a retrospective cohort study. Scientific Reports 11:1.
Crossref
Young Min Hur, Mi Na Kang & Young Ju Kim. (2021) Vaginal health in women and the possibility of predicting preterm birth through microbiome analysis. Journal of the Korean Medical Association 64:12, pages 833-840.
Crossref
Eunjung Jung, Roberto Romero, Bo Hyun Yoon, Kevin R. Theis, Dereje W. Gudicha, Adi L. Tarca, Ramiro Diaz-Primera, Andrew D. Winters, Nardhy Gomez-Lopez, Lami Yeo & Chaur-Dong Hsu. (2021) Bacteria in the amniotic fluid without inflammation: early colonization vs. contamination. Journal of Perinatal Medicine 49:9, pages 1103-1121.
Crossref
Pei F. Lai, Kaiyu Lei, Xiaoyu Zhan, Gavin Sooranna, Jonathan K. H. Li, Ektoras X. Georgiou, Ananya Das, Natasha Singh, Qiye Li, Zachary Stanfield, Guojie Zhang, Rachel M. Tribe, Sam Mesiano & Mark R. Johnson. (2021) Labour classified by cervical dilatation & fetal membrane rupture demonstrates differential impact on RNA-seq data for human myometrium tissues. PLOS ONE 16:11, pages e0260119.
Crossref
Amanda Brosius Lutz, Salwan Al-Nasiry, Boris W. Kramer & Martin Mueller. (2021) Understanding Host-Pathogen Interactions in Acute Chorioamnionitis Through the Use of Animal Models. Frontiers in Cellular and Infection Microbiology 11.
Crossref
V. F. Dolgushina, E. S. Alikhanova, I. V. Kurnosenko & T. V. Nadvikova. (2021) Isthmico-cervical insufficiency associated with cervicovaginal infections: features of the course of pregnancy and perinatal outcomes. Ural Medical Journal 20:1, pages 23-29.
Crossref
Karen Van Mechelen, Marisse Meeus, Veerle Matheeussen, Gilbert Donders, Yves Jacquemyn & Ludo Mahieu. (2020) Association between maternal cervicovaginal swab positivity for Ureaplasma spp. or other microorganisms and neonatal respiratory outcome and mortality. Journal of Perinatology 41:6, pages 1-11.
Crossref
Kenichiro Motomura, Roberto Romero, Jose Galaz, Adi L. Tarca, Bogdan Done, Yi Xu, Yaozhu Leng, Valeria Garcia-Flores, Marcia Arenas-Hernandez, Kevin R. Theis, Meyer Gershater, Eunjung Jung, Chaur-Dong Hsu & Nardhy Gomez-Lopez. (2021) RNA Sequencing Reveals Distinct Immune Responses in the Chorioamniotic Membranes of Women with Preterm Labor and Microbial or Sterile Intra-amniotic Inflammation. Infection and Immunity 89:5.
Crossref
Roberto Romero, Percy Pacora, Juan Pedro Kusanovic, Eunjung Jung, Bogdan Panaitescu, Eli Maymon, Offer Erez, Susan Berman, David R. Bryant, Nardhy Gomez-Lopez, Kevin R. Theis, Gaurav Bhatti, Chong Jai Kim, Bo Hyun Yoon, Sonia S. Hassan, Chaur-Dong Hsu, Lami Yeo, Ramiro Diaz-Primera, Julio Marin-Concha, Kia Lannaman, Ali Alhousseini, Hunter Gomez-Roberts, Aneesha Varrey, Angel Garcia-Sanchez & Maria Teresa Gervasi. (2021) Clinical chorioamnionitis at term X: microbiology, clinical signs, placental pathology, and neonatal bacteremia – implications for clinical care. Journal of Perinatal Medicine 49:3, pages 275-298.
Crossref
Jaroslav Stranik, Marian Kacerovsky, Ondrej Soucek, Martina Kolackova, Ivana Musilova, Lenka Pliskova, Radka Bolehovska, Pavel Bostik, Jana Matulova, Bo Jacobsson & Ctirad Andrys. (2021) IgGFc-binding protein in pregnancies complicated by spontaneous preterm delivery: a retrospective cohort study. Scientific Reports 11:1.
Crossref
Dereje W. Gudicha, Roberto Romero, Doron Kabiri, Edgar Hernandez-Andrade, Percy Pacora, Offer Erez, Juan Pedro Kusanovic, Eunjung Jung, Carmen Paredes, Stanley M. Berry, Lami Yeo, Sonia S. Hassan, Chaur-Dong Hsu & Adi L. Tarca. (2021) Personalized assessment of cervical length improves prediction of spontaneous preterm birth: a standard and a percentile calculator. American Journal of Obstetrics and Gynecology 224:3, pages 288.e1-288.e17.
Crossref
Alessandra Coscia, Flaminia Bardanzellu, Elisa Caboni, Vassilios Fanos & Diego Giampietro Peroni. (2021) When a Neonate Is Born, So Is a Microbiota. Life 11:2, pages 148.
Crossref
Matthew S. Payne, John P. Newnham, Dorota A. Doherty, Lucy L. Furfaro, Narisha L. Pendal, Diane E. Loh & Jeffrey A. Keelan. (2021) A specific bacterial DNA signature in the vagina of Australian women in midpregnancy predicts high risk of spontaneous preterm birth (the Predict1000 study). American Journal of Obstetrics and Gynecology 224:2, pages 206.e1-206.e23.
Crossref
L.A. Dal’nikovskaya, S.V. Novikova, T.S. Budykina, N.V. Biryukova, I.V. Klimova & I.R. Isubova. (2021) The value of the biochemical markers’ study for the diagnosis and prognosis of premature birth in women with a shortened cervix. Rossiiskii vestnik akushera-ginekologa 21:4, pages 14.
Crossref
Martina Chalupska, Marian Kacerovsky, Jaroslav Stranik, Miroslav Gregor, Jan Maly, Bo Jacobsson & Ivana Musilova. (2021) Intra-Amniotic Infection and Sterile Intra-Amniotic Inflammation in Cervical Insufficiency with Prolapsed Fetal Membranes: Clinical Implications. Fetal Diagnosis and Therapy 48:1, pages 58-69.
Crossref
Violetta Florova, Roberto Romero, Adi L. Tarca, Jose Galaz, Kenichiro Motomura, Madison M. Ahmad, Chaur-Dong Hsu, Richard Hsu, Anna Tong, Jacques Ravel, Kevin R. Theis & Nardhy Gomez-Lopez. (2021) Vaginal host immune-microbiome interactions in a cohort of primarily African-American women who ultimately underwent spontaneous preterm birth or delivered at term. Cytokine 137, pages 155316.
Crossref
Adi L. Tarca, Roberto Romero, Roger Pique-Regi, Percy Pacora, Bogdan Done, Marian Kacerovsky, Gaurav Bhatti, Sunil Jaiman, Sonia S. Hassan, Chaur-Dong Hsu & Nardhy Gomez-Lopez. (2020) Amniotic fluid cell-free transcriptome: a glimpse into fetal development and placental cellular dynamics during normal pregnancy. BMC Medical Genomics 13:1.
Crossref
Felicia Viklund, Maria Hallingström, Marian Kacerovsky, Teresa Cobo, Kristin Skogstrand, David M. Hougaard, Karin Sävman, Ylva Carlsson, Panagiotis Tsiartas, Julius Juodakis, Staffan Nilsson & Bo Jacobsson. (2020) Protein Concentrations of Thrombospondin-1, MIP-1β, and S100A8 Suggest the Reflection of a Pregnancy Clock in Mid-Trimester Amniotic Fluid. Reproductive Sciences 27:12, pages 2146-2157.
Crossref
Jose Galaz, Roberto Romero, Yi Xu, Derek Miller, Dustyn Levenson, Robert Para, Aneesha Varrey, Richard Hsu, Anna Tong, Sonia S. Hassan, Chaur-Dong Hsu & Nardhy Gomez-Lopez. (2020) Cellular immune responses in amniotic fluid of women with a sonographic short cervix. Journal of Perinatal Medicine 48:7, pages 665-676.
Crossref
Luis A. Monsivais, Samantha Sheller‐Miller, William Russell, George R. Saade, Christopher L. Dixon, Rheanna Urrabaz‐Garza & Ramkumar Menon. (2020) Fetal membrane extracellular vesicle profiling reveals distinct pathways induced by infection and inflammation in vitro. American Journal of Reproductive Immunology 84:3.
Crossref
K Motomura, R Romero, V Garcia-Flores, Y Leng, Y Xu, J Galaz, R Slutsky, D Levenson & N Gomez-Lopez. (2020) The alarmin interleukin-1α causes preterm birth through the NLRP3 inflammasome. Molecular Human Reproduction 26:9, pages 712-726.
Crossref
Courtney M. Jackson, Shibabrata Mukherjee, Adrienne N. Wilburn, Chris Cates, Ian P. Lewkowich, Hitesh Deshmukh, William J. Zacharias & Claire A. Chougnet. (2020) Pulmonary Consequences of Prenatal Inflammatory Exposures: Clinical Perspective and Review of Basic Immunological Mechanisms. Frontiers in Immunology 11.
Crossref
Russell G. Witt, Lily Blair, Michela Frascoli, Michael J. Rosen, Quoc-Hung Nguyen, Sivan Bercovici, Simona Zompi, Roberto Romero & Tippi C. Mackenzie. (2020) Detection of microbial cell-free DNA in maternal and umbilical cord plasma in patients with chorioamnionitis using next generation sequencing. PLOS ONE 15:4, pages e0231239.
Crossref
Sunil Jaiman, Roberto Romero, Percy Pacora, Eunjung Jung, Gaurav Bhatti, Lami Yeo, Yeon Mee Kim, Bomi Kim, Chong Jai Kim, Jung-Sun Kim, Faisal Qureshi, Suzanne M. Jacques, Offer Erez, Nardhy Gomez-Lopez & Chaur-Dong Hsu. (2020) Disorders of placental villous maturation in fetal death. Journal of Perinatal Medicine 0:0.
Crossref
Kevin R. Theis, Roberto Romero, Kenichiro Motomura, Jose Galaz, Andrew D. Winters, Percy Pacora, Derek Miller, Rebecca Slutsky, Violetta Florova, Dustyn Levenson, Robert Para, Aneesha Varrey, Marian Kacerovsky, Chaur-Dong Hsu & Nardhy Gomez-Lopez. (2020) Microbial burden and inflammasome activation in amniotic fluid of patients with preterm prelabor rupture of membranes. Journal of Perinatal Medicine 48:2, pages 115-131.
Crossref
Gaurav Bhatti, Roberto Romero, Gregory Edward Rice, Wendy Fitzgerald, Percy Pacora, Nardhy Gomez-Lopez, Mahendra Kavdia, Adi L. Tarca & Leonid Margolis. (2020) Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor. PLOS ONE 15:1, pages e0227881.
Crossref
S.V. Novikova, L.A. Dal’nikovskaya, T.S. Budykina, N.V. Biryukova & I.V. Klimova. (2020) Diagnostic and prognostic value of the study of biochemical markers of the threat of abortion in women with a short cervix. Rossiiskii vestnik akushera-ginekologa 20:4, pages 18.
Crossref
Nardhy Gomez‐Lopez, Roberto Romero, Adi L. Tarca, Derek Miller, Bogdan Panaitescu, George Schwenkel, Dereje W. Gudicha, Sonia S. Hassan, Percy Pacora, Eunjung Jung & Chaur‐Dong Hsu. (2019) Gasdermin D: Evidence of pyroptosis in spontaneous preterm labor with sterile intra‐amniotic inflammation or intra‐amniotic infection. American Journal of Reproductive Immunology 82:6.
Crossref
Nardhy Gomez-Lopez, Roberto Romero, Yaozhu Leng, Yi Xu, Rebecca Slutsky, Dustyn Levenson, Percy Pacora, Eunjung Jung, Bogdan Panaitescu & Chaur-Dong Hsu. (2019) The origin of amniotic fluid monocytes/macrophages in women with intra-amniotic inflammation or infection. Journal of Perinatal Medicine 47:8, pages 822-840.
Crossref
Bo Hyun Yoon, Roberto Romero, Jee Yoon Park, Kyung Joon Oh, JoonHo Lee, Agustin Conde-Agudelo & Joon-Seok Hong. (2019) Antibiotic administration can eradicate intra-amniotic infection or intra-amniotic inflammation in a subset of patients with preterm labor and intact membranes. American Journal of Obstetrics and Gynecology 221:2, pages 142.e1-142.e22.
Crossref
Kyung Joon Oh, Roberto Romero, Jee Yoon Park, Joon-Seok Hong & Bo Hyun Yoon. (2019) The earlier the gestational age, the greater the intensity of the intra-amniotic inflammatory response in women with preterm premature rupture of membranes and amniotic fluid infection by Ureaplasma species . Journal of Perinatal Medicine 47:5, pages 516-527.
Crossref
Yaozhu Leng, Roberto Romero, Yi Xu, Jose Galaz, Rebecca Slutsky, Marcia Arenas‐Hernandez, Valeria Garcia‐Flores, Kenichiro Motomura, Sonia S. Hassan, Andrea Reboldi & Nardhy Gomez‐Lopez. (2019) Are B cells altered in the decidua of women with preterm or term labor?. American Journal of Reproductive Immunology 81:5.
Crossref
Nardhy Gomez-Lopez, Roberto Romero, Valeria Garcia-Flores, Yaozhu Leng, Derek Miller, Sonia S Hassan, Chaur-Dong Hsu & Bogdan Panaitescu. (2019) Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes†. Biology of Reproduction 100:5, pages 1306-1318.
Crossref
Kyung Joon Oh, Roberto Romero, Jee Yoon Park, Jihyun Kang, Joon-Seok Hong & Bo Hyun Yoon. (2019) A high concentration of fetal fibronectin in cervical secretions increases the risk of intra-amniotic infection and inflammation in patients with preterm labor and intact membranes. Journal of Perinatal Medicine 47:3, pages 288-303.
Crossref
Nardhy Gomez-LopezRoberto Romero, Eli Maymon, Juan Pedro Kusanovic, Bogdan Panaitescu, Derek Miller, Percy Pacora, Adi L. Tarca, Kenichiro Motomura, Offer Erez, Eunjung Jung, Sonia S. Hassan & Chaur-Dong Hsu. (2019) Clinical chorioamnionitis at term IX: in vivo evidence of intra-amniotic inflammasome activation . Journal of Perinatal Medicine 47:3, pages 276-287.
Crossref
Kevin R. Theis, Roberto Romero, Andrew D. Winters, Jonathan M. Greenberg, Nardhy Gomez-Lopez, Ali Alhousseini, Janine Bieda, Eli Maymon, Percy Pacora, Jennifer M. Fettweis, Gregory A. Buck, Kimberly K. Jefferson, Jerome F. StraussIIIIII, Offer Erez & Sonia S. Hassan. (2019) Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics. American Journal of Obstetrics and Gynecology 220:3, pages 267.e1-267.e39.
Crossref
E. Merlot, H. Pastorelli, A. Prunier, M.-C. Père, I. Louveau, L. Lefaucheur, M.-H. Perruchot, M.C. Meunier-Salaün, D. Gardan-Salmon, F. Gondret & H. Quesnel. (2019) Sow environment during gestation: part I. Influence on maternal physiology and lacteal secretions in relation with neonatal survival. Animal 13:7, pages 1432-1439.
Crossref
Efrem S. Lim, Cynthia Rodriguez & Lori R. Holtz. (2018) Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community. Microbiome 6:1.
Crossref
Derek Miller, Kenichiro Motomura, Valeria Garcia-Flores, Roberto Romero & Nardhy Gomez-Lopez. (2018) Innate Lymphoid Cells in the Maternal and Fetal Compartments. Frontiers in Immunology 9.
Crossref
Aneesha Varrey, Roberto Romero, Bogdan Panaitescu, Derek Miller, Tinnakorn Chaiworapongsa, Manasi Patwardhan, Jonathan Faro, Percy Pacora, Sonia S. Hassan, Chaur‐Dong Hsu & Nardhy Gomez‐Lopez. (2018) Human β‐defensin‐1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra‐amniotic infection. American Journal of Reproductive Immunology 80:4.
Crossref
Goran AugustinGoran Augustin. 2018. Acute Abdomen During Pregnancy. Acute Abdomen During Pregnancy 789 819 .
Kia Lannaman, Roberto Romero, Tinnakorn Chaiworapongsa, Yeon Mee Kim, Steven J. Korzeniewski, Eli Maymon, Nardhy Gomez-Lopez, Bogdan Panaitescu, Sonia S. Hassan, Lami Yeo, Bo Hyun Yoon, Chong Jai Kim & Offer Erez. (2017) Fetal death: an extreme manifestation of maternal anti-fetal rejection. Journal of Perinatal Medicine 45:7, pages 851-868.
Crossref
Iben Sundtoft, Jens Langhoff‐Roos, Puk Sandager, Steffen Sommer & Niels Uldbjerg. (2017) Cervical collagen is reduced in non‐pregnant women with a history of cervical insufficiency and a short cervix. Acta Obstetricia et Gynecologica Scandinavica 96:8, pages 984-990.
Crossref
Kirstine Sneider, Ole Bjarne Christiansen, Iben Blaabjerg Sundtoft & Jens Langhoff-Roos. (2017) Recurrence rates after abdominal and vaginal cerclages in women with cervical insufficiency: a validated cohort study. Archives of Gynecology and Obstetrics 295:4, pages 859-866.
Crossref
Nardhy Gomez-Lopez, Roberto Romero, Yaozhu Leng, Valeria Garcia-Flores, Yi Xu, Derek Miller & Sonia S. Hassan. (2017) Neutrophil extracellular traps in acute chorioamnionitis: A mechanism of host defense. American Journal of Reproductive Immunology 77:3, pages e12617.
Crossref
A. M. Vintzileos & G. H. A. Visser. (2017) Interventions for women with mid‐trimester short cervix: which ones work?. Ultrasound in Obstetrics & Gynecology 49:3, pages 295-300.
Crossref
Meital Nuriel-Ohayon, Hadar Neuman & Omry Koren. (2016) Microbial Changes during Pregnancy, Birth, and Infancy. Frontiers in Microbiology 7.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.