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Original Article

Tumor Bioelectric Potential and its Possible Exploitation for Tumor Growth Retardation

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Pages 133-149 | Published online: 07 Jul 2009

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Antony K Teresa Infanta. S, Nisshanthini Durairaju, Senthil Raja, Thandeeswaran Murugesan, Anand Raj Dhanapal, Karupannan Natarajan, Ajithkumar Balakrishnan, Hemamalini Vedagiri, Palaniswamy Muthusamy & Angayarkanni Jayaraman. (2023) Pharmacological assessment of Ru(II) complex with GidA protein- A novel topoisomerase II inhibitor towards cancer therapeutics. Journal of Biomolecular Structure and Dynamics 41:9, pages 4143-4153.
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Magdy M. Ghannam, R. H. El-Gebaly, M. H. Gaber & Fadel M. Ali. (2002) INHIBITION OF EHRLICH TUMOR GROWTH IN MICE BY ELECTRIC INTERFERENCE THERAPY (IN VIVO STUDIES). Electromagnetic Biology and Medicine 21:3, pages 255-268.
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J. Berendson & J. M. Olsson. (1998) Bioelectrochemical Aspects of the Treatment of Tissue with Direct Current. Electro- and Magnetobiology 17:1, pages 1-16.
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Damijan Miklavčič, Dejan Šemrov, Vojko Valenčič, Gregor Serša & Lojze Vodovnik. (1997) Tumor Treatment by Direct Electric Current: Computation of Electric Current and Power Density Distribution. Electro- and Magnetobiology 16:2, pages 119-128.
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Bruce C. Towe, Farshad Shirazi & Ali Kakavand. (1996) Investigation of Cancer Tumor Biopotential in Relation to Tumor Ph. Electro- and Magnetobiology 15:1, pages 19-36.
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Damijan Miklavčič & Gregor Serša. (1992) Conflicting Data on Biological Systems Treated with Electrical Direct Current. Electro- and Magnetobiology 11:1, pages 67-69.
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Robert O. Becker. (1992) Effect of Anodally Generated Silver Ions on Fibrosarcoma Cells. Electro- and Magnetobiology 11:1, pages 57-65.
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Damijan Miklavĉiĉ, Lojze Vodovnik, Fedja Bobanovic, Stanislav Reberŝek, Gregor Serŝa, Srdjan Novaković & Rastko Golouh. (1992) Local Treatment of Murine Tumors by Electric Direct Current. Electro- and Magnetobiology 11:2, pages 109-125.
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Silvia Schoch, Simona Braccini, Lorenzo Biancalana, Alessandro Pratesi, Tiziana Funaioli, Stefano Zacchini, Guido Pampaloni, Federica Chiellini & Fabio Marchetti. (2022) When ferrocene and diiron organometallics meet: triiron vinyliminium complexes exhibit strong cytotoxicity and cancer cell selectivity. Inorganic Chemistry Frontiers 9:20, pages 5118-5139.
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Amir Mokhtare, M. Shiv Krishna Reddy, Venoos Amiri Roodan, Edward P. Furlani & Alireza Abbaspourrad. (2019) The role of pH fronts, chlorination and physicochemical reactions in tumor necrosis in the electrochemical treatment of tumors: A numerical study. Electrochimica Acta 307, pages 129-147.
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E. Luján, H. Schinca, N. Olaiz, S. Urquiza, F.V. Molina, P. Turjanski & G. Marshall. (2015) Optimal dose-response relationship in electrolytic ablation of tumors with a one-probe-two-electrode device. Electrochimica Acta 186, pages 494-503.
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Michael I. Webb, Ryan A. Chard, Yaser M. Al-Jobory, Michael R. Jones, Edwin W. Y. Wong & Charles J. Walsby. (2011) Pyridine Analogues of the Antimetastatic Ru(III) Complex NAMI-A Targeting Non-Covalent Interactions with Albumin. Inorganic Chemistry 51:2, pages 954-966.
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A.K. Dubey, K. Balani & B. Basu. 2012. Nanomedicine. Nanomedicine 537 570 .
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A M Hassan & M El-Shenawee. (2010) Modeling Biopotential Signals and Current Densities of Multiple Breast Cancerous Cells. IEEE Transactions on Biomedical Engineering 57:9, pages 2099-2106.
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Andrés Ramírez Aguilera, Luis Enrique Bergues Cabrales, Héctor Manuel Camué Ciria, Yudelmis Soler Pérez, Fidel Gilart González, Maraelys Morales González, Lisset Ortíz Zamora, Fabiola Suárez Palencia, Miriam Fariñas Salas, Nailet Real Bestard, Gustavo Sierra González & Idelisa Bergues Cabrales. (2010) Electric current density distribution in planar solid tumor and its surrounding healthy tissue generated by an electrode elliptic array used in electrotherapy. Mathematics and Computers in Simulation 80:9, pages 1886-1902.
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P. Turjanski, N. Olaiz, P. Abou-Adal, C. Suárez, M. Risk & G. Marshall. (2009) pH front tracking in the electrochemical treatment (EChT) of tumors: Experiments and simulations. Electrochimica Acta 54:26, pages 6199-6206.
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Andrés Ramírez Aguilera, Luis Enrique Bergues Cabrales, Héctor Manuel Camué Ciria, Yudelmis Soler Pérez, Eduardo Roca Oria, Soraida Acosta Brooks & Tamara Rubio González. (2009) Distributions of the potential and electric field of an electrode elliptic array used in tumor electrotherapy: Analytical and numerical solutions. Mathematics and Computers in Simulation 79:7, pages 2091-2105.
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L. Colombo, G. González, G. Marshall, F.V. Molina, A. Soba, C. Suarez & P. Turjanski. (2007) Ion transport in tumors under electrochemical treatment: In vivo, in vitro and in silico modeling. Bioelectrochemistry 71:2, pages 223-232.
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Neva Bešker, Cecilia Coletti, Alessandro Marrone & Nazzareno Re. (2007) Binding of Antitumor Ruthenium Complexes to DNA and Proteins:  A Theoretical Approach. The Journal of Physical Chemistry B 111:33, pages 9955-9964.
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Michael Groessl, Erwin Reisner, Christian G. Hartinger, Rene Eichinger, Olga Semenova, Andrei R. Timerbaev, Michael A. Jakupec, Vladimir B. Arion & Bernhard K. Keppler. (2007) Structure−Activity Relationships for NAMI-A-type Complexes (HL)[ trans -RuCl 4 L( S -dmso)ruthenate(III)] (L = Imidazole, Indazole, 1,2,4-Triazole, 4-Amino-1,2,4-triazole, and 1-Methyl-1,2,4-triazole):  Aquation, Redox Properties, Protein Binding, and Antiproliferative Activity . Journal of Medicinal Chemistry 50:9, pages 2185-2193.
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José Ribamar O. Filho, Welter C. Silva, José Clayston M. Pereira & Douglas W. Franco. (2006) Binding of cysteine and glutathione to Ru(II) and Ru(III) centers: Formation and products reactivities. Inorganica Chimica Acta 359:9, pages 2888-2895.
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