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Review Article

Danger, intracellular signaling, and the orchestration of dendritic cell function in skin sensitization

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Pages 223-234 | Received 22 May 2012, Accepted 29 Jun 2012, Published online: 07 Sep 2012

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Hillary L. Shane, Carrie M. Long & Stacey E. Anderson. (2019) Novel cutaneous mediators of chemical allergy. Journal of Immunotoxicology 16:1, pages 13-27.
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Stacey E. Anderson, B. Jean Meade, Carrie M. Long, Ewa Lukomska & Nikki B. Marshall. (2016) Investigations of immunotoxicity and allergic potential induced by topical application of triclosan in mice. Journal of Immunotoxicology 13:2, pages 165-172.
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Articles from other publishers (28)

Mark A. Pemberton & Ian Kimber. (2023) Propylene glycol, skin sensitisation and allergic contact dermatitis: A scientific and regulatory conundrum. Regulatory Toxicology and Pharmacology 138, pages 105341.
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David A. Basketter & Ian Kimber. (2022) Enzymes and sensitization via skin exposure: A critical analysis. Regulatory Toxicology and Pharmacology 129, pages 105112.
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Fateme Nazary Abrbekoh, Leila Salimi, Sepideh Saghati, Hassan Amini, Sonia Fathi Karkan, Keyvan Moharamzadeh, Emel Sokullu & Reza Rahbarghazi. (2022) Application of microneedle patches for drug delivery; doorstep to novel therapies. Journal of Tissue Engineering 13, pages 204173142210853.
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Robin Gradin, Andy Forreryd, Ulrika Mattson, Anders Jerre & Henrik Johansson. (2021) Quantitative assessment of sensitizing potency using a dose–response adaptation of GARDskin. Scientific Reports 11:1.
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Christen Brown & JiaDe Yu. (2021) Pediatric Allergic Contact Dermatitis. Immunology and Allergy Clinics of North America 41:3, pages 393-408.
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Ian Kimber. (2021) The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analyses. Regulatory Toxicology and Pharmacology 119, pages 104821.
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Ana Isabel Sebastião, Isabel Ferreira, Gonçalo Brites, Ana Silva, Bruno Miguel Neves & Maria Teresa Cruz. (2020) NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify. Pharmaceutics 12:9, pages 867.
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Amélie Thélu, Sophie Catoire & Saadia Kerdine-Römer. (2020) Immune-competent in vitro co-culture models as an approach for skin sensitisation assessment. Toxicology in Vitro 62, pages 104691.
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Henrik Johansson, Robin Gradin, Angelica Johansson, Els Adriaens, Amber Edwards, Veronika Zuckerstätter, Anders Jerre, Florence Burleson, Helge Gehrke & Erwin L Roggen. (2019) Validation of the GARD™skin Assay for Assessment of Chemical Skin Sensitizers: Ring Trial Results of Predictive Performance and Reproducibility. Toxicological Sciences 170:2, pages 374-381.
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Ian Kimber. (2019) The activity of methacrylate esters in skin sensitisation test methods: A review. Regulatory Toxicology and Pharmacology 104, pages 14-20.
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Hillary L Shane, Ewa Lukomska, Michael L Kashon & Stacey E Anderson. (2019) Topical Application of the Quaternary Ammonium Compound Didecyldimethylammonium Chloride Activates Type 2 Innate Lymphoid Cells and Initiates a Mixed-Type Allergic Response. Toxicological Sciences 168:2, pages 508-518.
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Nicola Gilmour, Ian Kimber, Jason Williams & Gavin Maxwell. (2018) Skin sensitization: Uncertainties, challenges, and opportunities for improved risk assessment. Contact Dermatitis 80:3, pages 195-200.
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Hanae Kobayashi-Tsukumo, Kanami Oiji, Dan Xie, Yuka Sawada, Kunihiko Yamashita, Shinichi Ogata, Hajime Kojima & Hiroshi Itagaki. (2019) Eliminating the contribution of lipopolysaccharide to protein allergenicity in the human cell-line activation test (h-CLAT). The Journal of Toxicological Sciences 44:4, pages 283-297.
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Michela Mori, Antonella Praticò, Roberta Villa, Alice Buzzella, Riccardo Vicini, Silvia Busoli Badiale, Ornella Pastoris, Claudio Angelinetta & Maurizio Barbieri Carones. (2018) Evaluation of safety and skin tolerability of organic cotton pads in case of irritative vulvitis. Minerva Ginecologica 70:6.
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Ian Kimber, Alan Poole & David A. Basketter. (2018) Skin and respiratory chemical allergy: confluence and divergence in a hybrid adverse outcome pathway. Toxicology Research 7:4, pages 586-605.
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Hanae Tsukumo, Natsumi Matsunari, Kunihiko Yamashita, Hajime Kojima & Hiroshi Itagaki. (2018) Lipopolysaccharide interferes with the use of the human Cell Line Activation Test to determine the allergic potential of proteins. Journal of Pharmacological and Toxicological Methods 92, pages 34-42.
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S.E. Anderson & B.J. Meade. 2018. Comprehensive Toxicology. Comprehensive Toxicology 542 558 .
Joseph S. Ainscough, G. Frank Gerberick, Ian Kimber & Rebecca J. Dearman. (2015) Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin. Journal of Biological Chemistry 290:52, pages 31151-31161.
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Françoise Cottrez, Elodie Boitel, Claude Auriault, Pierre Aeby & Hervé Groux. (2015) Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay. Toxicology in Vitro 29:4, pages 787-802.
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Margarida Gonçalo, João Martins, Ana Silva, Bruno Neves, Américo Figueiredo, Teresa Cruz & Celeste Lopes. (2015) Systemic drugs inducing non-immediate cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells. Journal of Applied Toxicology 35:4, pages 398-406.
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Kerstin Reisinger, Sebastian Hoffmann, Nathalie Alépée, Takao Ashikaga, Joao Barroso, Cliff Elcombe, Nicola Gellatly, Valentina Galbiati, Susan Gibbs, Hervé Groux, Jalila Hibatallah, Donald Keller, Petra Kern, Martina Klaric, Susanne Kolle, Jochen Kuehnl, Nathalie Lambrechts, Malin Lindstedt, Marion Millet, Silvia Martinozzi-Teissier, Andreas Natsch, Dirk Petersohn, Ian Pike, Hitoshi Sakaguchi, Andreas Schepky, Magalie Tailhardat, Marie Templier, Erwin van Vliet & Gavin Maxwell. (2015) Systematic evaluation of non-animal test methods for skin sensitisation safety assessment. Toxicology in Vitro 29:1, pages 259-270.
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Ilona J. Kosten, Jeroen K. Buskermolen, Sander W. Spiekstra, Tanja D. de Gruijl & Susan Gibbs. (2015) Gingiva Equivalents Secrete Negligible Amounts of Key Chemokines Involved in Langerhans Cell Migration Compared to Skin Equivalents. Journal of Immunology Research 2015, pages 1-11.
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Valentina Galbiati, Angela Papale, Corrado L. Galli, Marina Marinovich & Emanuela Corsini. (2014) Role of ROS and HMGB1 in Contact Allergen–Induced IL-18 Production in Human Keratinocytes. Journal of Investigative Dermatology 134:11, pages 2719-2727.
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Ian Kimber & Mark A. Pemberton. (2014) Assessment of the skin sensitising potency of the lower alkyl methacrylate esters. Regulatory Toxicology and Pharmacology 70:1, pages 24-36.
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Ian Kimber, Rebecca J. Dearman, David A. Basketter & Darrell R. Boverhof. (2014) Chemical respiratory allergy: Reverse engineering an adverse outcome pathway. Toxicology 318, pages 32-39.
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Stacey E. AndersonB. Jean Meade. (2014) Potential Health Effects Associated with Dermal Exposure to Occupational Chemicals. Environmental Health Insights 8s1, pages EHI.S15258.
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Emanuela Corsini. 2005. Encyclopedia of Immunotoxicology. Encyclopedia of Immunotoxicology 1 8 .
J.P. McFadden, P. Puangpet, D.A. Basketter, R.J. Dearman & I. Kimber. (2013) Why does allergic contact dermatitis exist?. British Journal of Dermatology 168:4, pages 692-699.
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