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Research Article

Characterization of the T-dependent antibody response (TDAR) to keyhole limpet hemocyanin (KLH) in the Göttingen minipig

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Pages 376-382 | Received 15 Aug 2013, Accepted 06 Oct 2013, Published online: 12 Nov 2013

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Wenhua Zhong, Penghuan Chang, Lianfang Gan, Lifan Zhong & Zhaoxin Yang. (2022) A T-cell-dependent antibody response (TDAR) method in BALB/c mice based on a cytometric bead array. Journal of Immunotoxicology 19:1, pages 34-40.
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Penghuan Chang, Ling Huang, Mianqing Huang, Shuhong Tian & Zhaoxin Yang. (2019) Improvement and optimization of a T-cell-dependent antibody response (TDAR) method for BALB/c mice using keyhole limpet hemocyanin (KLH) as specific antigen. Journal of Immunotoxicology 16:1, pages 149-154.
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Tatiana Flisikowska, Jerome Egli, Krzysztof Flisikowski, Marlene Stumbaum, Erich Küng, Martin Ebeling, Roland Schmucki, Guy Georges, Thomas Singer, Mayuko Kurome, Barbara Kessler, Valeri Zakhartchenko, Eckhard Wolf, Felix Weber, Angelika Schnieke & Antonio Iglesias. (2022) A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies. Nature Biomedical Engineering 6:11, pages 1248-1256.
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Cathy Nguyen & Lars Petter Jordheim. (2023) Évaluation de l’immunotoxicité en recherche et dans le cadre du développement biomédical. Biologie Aujourd’hui 216:3-4, pages 167-181.
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Jing Xing, Wenjing Liu, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi & Wenbin Zhan. (2021) The Expression of CD28 and Its Synergism on the Immune Response of Flounder (Paralichthys olivaceus) to Thymus-Dependent Antigen. Frontiers in Immunology 12.
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Kaylee E. Hahn, Irina Dahms, Christopher M. Butt, Norman SalemJr.Jr., Vivian Grimshaw, Eileen Bailey, Stephen A. Fleming, Brooke N. Smith & Ryan N. Dilger. (2020) Impact of Arachidonic and Docosahexaenoic Acid Supplementation on Neural and Immune Development in the Young Pig. Frontiers in Nutrition 7.
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János Szebeni & Raj Bawa. (2020) Human Clinical Relevance of the Porcine Model of Pseudoallergic Infusion Reactions. Biomedicines 8:4, pages 82.
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Jinze Li, Mayur S. Mitra & Gautham K. Rao. 2020. Immuno-Oncology. Immuno-Oncology 199 238 .
Jing Xing, Keke Luo, Yue'e Xiao, Xiaoqian Tang & Wenbin Zhan. (2019) Influence of CD4-1+, CD4-2+ and CD8+ T lymphocytes subpopulations on the immune response of B lymphocytes in flounder (Paralichthys olivaceus) immunized with thymus-dependent or thymus-independent antigen. Fish & Shellfish Immunology 84, pages 979-986.
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Jacques Descotes, Linda Allais, Philippe Ancian, Henrik Duelund Pedersen, Claire Friry-Santini, Antonio Iglesias, Tina Rubic-Schneider, Hollie Skaggs & Peter Vestbjerg. (2018) Nonclinical evaluation of immunological safety in Göttingen Minipigs: The CONFIRM initiative. Regulatory Toxicology and Pharmacology 94, pages 271-275.
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X. Wang, A. Coppi & H. Lebrec. 2018. Comprehensive Toxicology. Comprehensive Toxicology 376 398 .
L. Peyton Myers. 2018. Immunotoxicity Testing. Immunotoxicity Testing 15 26 .
Jing Xing, Yue'e Xiao, Xiaoqian Tang, Xiuzhen Sheng & Wenbin Zhan. (2017) Inhibition of Cyclosporine A or rapamycin on T lymphocyte counts and the influence on the immune responses of B lymphocytes in flounder ( Paralichthys olivaceus ). Fish & Shellfish Immunology 66, pages 78-85.
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Tina Rubic-Schneider, Brigitte Christen, Dominique Brees & Michael Kammüller. (2016) Minipigs in Translational Immunosafety Sciences. Toxicologic Pathology 44:3, pages 315-324.
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