1,132
Views
44
CrossRef citations to date
0
Altmetric
Research Article

Management of intentional superwarfarin poisoning with long-term vitamin K and brodifacoum levels

, &
Pages 385-390 | Received 25 Mar 2011, Accepted 06 May 2011, Published online: 08 Jul 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Daniel G. Nosal, Richard B. van Breemen, John W. Haffner, Israel Rubinstein & Douglas L. Feinstein. (2021) Brodifacoum pharmacokinetics in acute human poisoning: implications for estimating duration of vitamin K therapy. Toxicology Communications 5:1, pages 69-72.
Read now
Jason M. Devgun, Arkady Rasin, Theresa Kim, Mark B. Mycyk, Sean M. Bryant, Michael S. Wahl, Carol DesLauriers, Livia Navon, Erin D. Moritz, Trevonne M. Thompson, Henry D. Swoboda, Jenny Lu & Steven E. Aks. (2020) An outbreak of severe coagulopathy from synthetic cannabinoids tainted with Long-Acting anticoagulant rodenticides. Clinical Toxicology 58:8, pages 821-828.
Read now
Douglas L Feinstein, Daniel G Nosal, Swetha Ramanathan, Jifang Zhou, Luying Chen, Ronald C Hershow, Richard B van Breemen, Erik Wright, John W Hafner & Israel Rubinstein. (2020) Effects of vitamin K1 treatment on plasma concentrations of long-acting anticoagulant rodenticide enantiomers following inhalation of contaminated synthetic cannabinoids. Clinical Toxicology 58:7, pages 716-724.
Read now
Israel Rubinstein, Guy Weinberg, Richard van Breemen, Ronald C. Hershow & Douglas L. Feinstein. (2018) Treatment for long acting anticoagulant rodenticide poisoning – beyond INR monitoring?. Toxicology Communications 2:1, pages 59-61.
Read now
Meiling Wang, Yanfeng Yang, Yiwei Hou, Wenbin Ma, Rui Jia & Jinbo Chen. (2017) Effects of bromadiolone poisoning on the central nervous system. Neuropsychiatric Disease and Treatment 13, pages 2297-2300.
Read now
Hui Yan, Lin Zhu, Xianyi Zhuo, Min Shen & Ping Xiang. (2016) Anticoagulant rodenticide intoxication in east China: a three-year analysis. Forensic Sciences Research 1:1, pages 22-27.
Read now

Articles from other publishers (38)

Alek Q. Adkins. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 261 266 .
Natalie Mathews, Subia Tasneem & Catherine P. M. Hayward. (2023) Rare inherited coagulation and fibrinolytic defects that challenge diagnostic laboratories. International Journal of Laboratory Hematology 45:S2, pages 30-43.
Crossref
Mahvish Haider, Carlos Acevedo-Cajigas, Desiree Ortiz, Christian A Zorrilla & Jorge Perez. (2023) Persistent Coagulopathy After Synthetic Cannabinoid Use. Cureus.
Crossref
Lin Guodong, Wu Jieyi, Peng Xiaobo, Lu Xiaoxia, Liu Zhongying, Pan Zhiguo, Qiu Zewu & Dong Jianguang. (2022) Retrospective analysis of clinical characteristics of and treatment strategies for patients with long‐acting anticoagulant rodenticide poisoning. Basic & Clinical Pharmacology & Toxicology 131:1, pages 74-82.
Crossref
Rami Abi Khalil, Brigitte Barbier, Ambre Fafournoux, Ali Barka Mahamat, Aurélie Marquez, Kevin Poissenot, Matthieu Keller, Amélie Desvars-Larrive, Javier Fernandez-De-Simon, Michael Coeurdassier, Etienne Benoit, Sébastien Lefebvre, Adrien Pinot & Virginie Lattard. (2021) Seasonal diet-based resistance to anticoagulant rodenticides in the fossorial water vole (Arvicola amphibius). Environmental Research 200, pages 111422.
Crossref
Mario Pezzo, Marica Orioli, Mauro Pagani, Simone Caiola, Giancarlo Maria Liumbruno & Massimo Franchini. (2021) Superwarfarin poisoning: a challenging diagnosis. Diagnosis 0:0.
Crossref
Aili Lu, Fang Yuan, Yufei Yao, Wanxin Wen, Hongji Lu, Shibiao Wu & Lixin Wang. (2021) Reversible leukoencephalopathy caused by 2 rodenticides bromadiolone and fluroacetamide. Medicine 100:9, pages e25053.
Crossref
V. V. Voytsekhovskiy, A. V. Pivnik, E. A. Filatova, T. V. Еseninа, K. M. Mishkurova & N. A. Fedorova. (2020) Coagulopathy at intoxication with rodenticides – antagonists of vitamin K. Bulletin Physiology and Pathology of Respiration:78, pages 161-177.
Crossref
Daniel G Nosal, Douglas L Feinstein, Luying Chen & Richard B van Breemen. (2020) Separation and Quantification of Superwarfarin Rodenticide Diastereomers—Bromadiolone, Difenacoum, Flocoumafen, Brodifacoum, and Difethialone—in Human Plasma. Journal of AOAC INTERNATIONAL 103:3, pages 770-778.
Crossref
Luke Yip, Noel V. Stanton & Robert A. Middleberg. (2020) Vitamin K 1 Treatment Duration in Patients with Brodifacoum Poisoning . New England Journal of Medicine 382:18, pages 1764-1765.
Crossref
Ryan Laurence Love, Naveen Sharma & Katie Chong. (2019) Unusual presentation of haemoptysis following accidental inhalation of the ‘superwarfarin’ rodenticide brodifacoum. BMJ Case Reports 12:11, pages e230044.
Crossref
Adrienne Markiewicz, Jennifer McMahon, Pamela Souders, Ann Parks & Sarah Peppard. (2019) Spontaneous Hemorrhage Associated With Synthetic Cannabinoid Use. The Journal for Nurse Practitioners 15:10, pages 749-753.
Crossref
J. H. Gerth, A. Hansch & H. H. Sigusch. (2019) Ungewöhnliche Ursache einer spontanen Makrohämaturie bei einem 19-jährigen MannUnusual cause of spontaneous macrohematuria in a 19-year-old man. Der Nephrologe 14:5, pages 370-373.
Crossref
Yeow-Kuan ChongTony Wing-Lai Mai. (2019) Superwarfarin (Long-Acting Anti-coagulant Rodenticides) Poisoning: from Pathophysiology to Laboratory-Guided Clinical Management. Clinical Biochemist Reviews 40:4, pages 175-185.
Crossref
Miguel A. Escobar. 2019. Consultative Hemostasis and Thrombosis. Consultative Hemostasis and Thrombosis 59 79 .
Matthew Lindeblad, Alexander Lyubimov, Richard van Breemen, Kamil Gierszal, Guy Weinberg, Israel Rubinstein & Douglas L Feinstein. (2018) The Bile Sequestrant Cholestyramine Increases Survival in a Rabbit Model of Brodifacoum Poisoning. Toxicological Sciences 165:2, pages 389-395.
Crossref
Zheng Qiao, Ping Xiang, Baohua Shen, Min Shen & Hui Yan. (2018) Simultaneous Determination of 13 Anticoagulant Rodenticidesin Human Blood by Liquid Chromatography–Tandem Mass Spectrometry and its Application in Three Poisoning Cases. Journal of Forensic Sciences 63:3, pages 784-792.
Crossref
Danielle Reimer, Melissa Smith & Sayed Ali. (2017) Deliberate self-poisoning with long-acting anticoagulant rodenticides. BMJ Case Reports, pages bcr-2017-222170.
Crossref
Valery V. Wojciechowski, Daniela Calina, Konstantinos Tsarouhas, Alexander V. Pivnik, Alexander A. Sergievich, Vladimir V. Kodintsev, Ekaterina A. Filatova, Eren Ozcagli, Anca Oana Docea, Andreea Letitia Arsene, Eliza Gofita, Christina Tsitsimpikou, Aristidis M. Tsatsakis & Kirill S. Golokhvast. (2017) A guide to acquired vitamin K coagulophathy diagnosis and treatment: the Russian perspective. DARU Journal of Pharmaceutical Sciences 25:1.
Crossref
Mingsheng Ma, Mengqi Zhang, Xiaoyan Tang & Zhenghong Li. (2017) Massive neonatal intracranial hemorrhage caused by bromadiolone. Medicine 96:45, pages e8506.
Crossref
Sarah L. Anderson, Robbie S. Kattappuram, Joel C. Marrs & Nicole M. Joseph. (2017) Intentional Brodifacoum Ingestion. The American Journal of Medicine 130:1, pages e27-e28.
Crossref
Chris Kostakis, Peter Harpas & Peter C. Stockham. 2017. Liquid Chromatography. Liquid Chromatography 301 358 .
George Sam Wang. 2017. Critical Care Toxicology. Critical Care Toxicology 1325 1339 .
Jianhai Long, Xiaobo Peng, Yuan Luo, Yawei Sun, Guodong Lin, Yongan Wang & Zewu Qiu. (2016) Treatment of a long-acting anticoagulant rodenticide poisoning cohort with vitamin K1 during the maintenance period. Medicine 95:51, pages e5461.
Crossref
Douglas L. Feinstein, Belinda S. Akpa, Manuela A. Ayee, Anne I. Boullerne, David Braun, Sergey V. Brodsky, David Gidalevitz, Zane Hauck, Sergey Kalinin, Kathy Kowal, Ivan Kuzmenko, Kinga Lis, Natalia Marangoni, Michael W. Martynowycz, Israel Rubinstein, Richard van Breemen, Kyle Ware & Guy Weinberg. (2016) The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures. Annals of the New York Academy of Sciences 1374:1, pages 111-122.
Crossref
D. Nicholas Bateman & Colin B. Page. (2016) Antidotes to coumarins, isoniazid, methotrexate and thyroxine, toxins that work via metabolic processes. British Journal of Clinical Pharmacology 81:3, pages 437-445.
Crossref
George Sam Wang. 2016. Critical Care Toxicology. Critical Care Toxicology 1 16 .
RJ Quy, TJ Gibson, MS Lambert, CT Eason & NG Gregory. (2023) Evaluation of a novel rodenticide: acute sub-lethal effects of a methaemoglobin-inducing agent. Animal Welfare 24:4, pages 427-436.
Crossref
Nathan King & Minh-Ha Tran. (2015) Long-Acting Anticoagulant Rodenticide (Superwarfarin) Poisoning: A Review of Its Historical Development, Epidemiology, and Clinical Management. Transfusion Medicine Reviews 29:4, pages 250-258.
Crossref
S. Bidny, K. Gago, M. David, T. Duong, D. Albertyn & N. Gunja. (2015) A Validated LC-MS-MS Method for Simultaneous Identification and Quantitation of Rodenticides in Blood. Journal of Analytical Toxicology 39:3, pages 219-224.
Crossref
N Othman, Ck Chan & Fl Lau. (2017) The Epidemiology of Household Rodenticides Poisoning in Hong Kong and its Risk Factors for Developing Coagulopathy. Hong Kong Journal of Emergency Medicine 21:6, pages 339-345.
Crossref
Hsin-Ying Yu, Ja-Liang Lin, Jen-Fen Fu, Jui-Hsiang Lin, Shou-Hsuan Liu, Cheng-Hao Weng, Wen-Hung Huang, Kuan-Hsing Chen, Ching-Wei Hsu & Tzung-Hai Yen. (2013) Outcomes of patients with rodenticide poisoning at a far east poison center. SpringerPlus 2:1.
Crossref
Krista M. Mehlhaff, Carmen C. Baxter, Kari Rudinsky & David S. McKenna. (2013) Lethal Neonatal Coagulopathy After Maternal Ingestion of a Superwarfarin. Obstetrics & Gynecology 122:2, pages 500-502.
Crossref
Emily Lovallo, Sarah Patterson, Mitchel Erickson, Cynthia Chin, Paul Blanc & Timur S. Durrani. (2013) When Is “Pseudo–Ludwig’s Angina” Associated With Coagulopathy Also a “Pseudo” Hemorrhage?. Journal of Investigative Medicine High Impact Case Reports 1:2, pages 232470961349250.
Crossref
Jiří Patočka, Georg Petroianu & Kamil Kuča. (2013) TOXIC POTENTIAL OF SUPERWARFARIN: BRODIFACOUM. Military Medical Science Letters 82:1, pages 32-38.
Crossref
Miguel A. Escobar & Harold R. Roberts. 2013. Consultative Hemostasis and Thrombosis. Consultative Hemostasis and Thrombosis 60 78 .
C. Kostakis, P. Harpas & P. Stockham. 2013. Liquid Chromatography. Liquid Chromatography 249 293 .
Jay Lipshitz, Thandavababu Chelliah & Louis Aledort. (2011) A case of factor V inhibitor with complete correction of the PT and aPTT upon mixing. American Journal of Hematology 87:3, pages 313-315.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.