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Clinical Toxicology Volume 53, 2015 - Issue 1
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Critical Care

Comparison of F(ab’)2 versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial

Sean P. BushEast Carolina University Brody School of Medicine/Vidant Medical Center, Greenville, NC, USACorrespondence[email protected]
,
Anne-Michelle RuhaBanner Good Samaritan Medical Center, Phoenix, AZ, USA
,
Steven A. SeifertUniversity of New Mexico Health Sciences Center, Albuquerque, NM, USA
,
David L. MorganScott and White Memorial Hospital, Temple, TX, USA
,
Brandon J. LewisSaint Josephs Hospital, Bryan, TX, USA
,
Thomas C. ArnoldLouisiana State University Health Sciences Center, Shreveport, LA, USA
,
Richard F. ClarkUniversity of California Medical Center, San Diego, CA, USA
,
William J. MeggsEast Carolina University Brody School of Medicine/Vidant Medical Center, Greenville, NC, USA
,
Eric A. ToschlogEast Carolina University Brody School of Medicine/Vidant Medical Center, Greenville, NC, USA
,
Stephen W. BorronPaul L. Foster School of Medicine/Texas Tech University Health Sciences Center, El Paso, TX, USA
,
Gary R. FiggeNorthwest Medical Center, Tucson, AZ, USA
,
Dawn R. SolleeUF Health Jacksonville, Jacksonville, FL, USA
,
Farshad M. ShiraziArizona Poison & Drug Information Center, Tucson, AZ, USA
,
Robert WolkTucson Medical Center, Tucson, AZ, USA
,
Ives de ChazalTucson Medical Center, Tucson, AZ, USA
,
Dan QuanMaricopa Medical Center, Phoenix, AZ, USA
,
Walter García-UbbelohdeInstituto Bioclon, México Distrito Federal, Mexico
,
Alejandro AlagónUNAM, Avenida Universidad 2001, Cuernavaca, Mexico
,
Richard D. GerkinBanner Good Samaritan Medical Center, Phoenix, AZ, USA
&
Leslie V. BoyerUniversity of Arizona Health Sciences Center, Tucson, AZ, USA
 show all
Pages 37-45 | Received 05 Aug 2014, Accepted 04 Oct 2014, Published online: 31 Oct 2014

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Meghan Beth Spyres, Gabriel K. Padilla, Richard D. Gerkin, Christopher O. Hoyte, Brian Joseph Wolk & Anne-Michelle Ruha. (2022) Late hemotoxicity following North American rattlesnake envenomation treated with crotalidae immune F(ab’)2 (equine) antivenom and crotalidae immune polyvalent Fab (ovine) antivenom reported to the North American Snakebite Sub-registry. Clinical Toxicology 60:7, pages 838-842.
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Charles J. Gerardo, Daniel E. Keyler, Malin Rapp-Olson & Richard C. Dart. (2022) Control of venom-induced tissue injury in copperhead snakebite patients: a post hoc sub-group analysis of a clinical trial comparing F(ab’)2 to Fab antivenom. Clinical Toxicology 60:4, pages 521-523.
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B. Z. Wilson, J. Larsen, G. Smelski, S. Dudley & F. M. Shirazi. (2021) Use of Crotalidae equine immune F(ab’)2 antivenom for treatment of an Agkistrodon envenomation. Clinical Toxicology 59:11, pages 1023-1026.
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Thomas Lamb, David Stewart, David A. Warrell, David G. Lalloo, Pardeep Jagpal, Dacia Jones, Ruben Thanacoody, Laurence A. Gray & Michael Eddleston. (2021) Moderate-to-severe Vipera berus envenoming requiring ViperaTAb antivenom therapy in the UK. Clinical Toxicology 59:11, pages 992-1001.
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Sam Ontiveros, Richard F. Clark & Alicia B. Minns. (2021) Acute hypersensitivity reaction from administration of crotalidae immune F(ab’)2 antivenom. Clinical Toxicology 59:7, pages 676-676.
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D. Paniagua, I. Vergara, R. Román, C. Romero, M. Benard-Valle, A. Calderón, L. Jiménez, M. J. Bernas, M. H. Witte, L. V. Boyer & A. Alagón. (2019) Antivenom effect on lymphatic absorption and pharmacokinetics of coral snake venom using a large animal model. Clinical Toxicology 57:8, pages 727-734.
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Eric J Lavonas & Charles J Gerardo. (2019) Letter to the editor: “Safety of nonsteroidal anti-inflammatory drugs in copperhead snakebite patients” by Pham and Mullins, Clin Toxicol 2018 May 18. Clinical Toxicology 57:2, pages 144-145.
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Thomas Lamb, Luc de Haro, Davide Lonati, Miran Brvar & Michael Eddleston. (2017) Antivenom for European Vipera species envenoming. Clinical Toxicology 55:6, pages 557-568.
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Steven A. Seifert. (2017) Clinical toxicology: past and future. Clinical Toxicology 55:5, pages 311-312.
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Charles J. Gerardo, Joao R. Nickenig Vissoci, Michael W. J. Brown & Sean P. Bush. (2017) Coagulation parameters in copperhead compared to other Crotalinae envenomation: secondary analysis of the F(ab’)2 versus Fab antivenom trial. Clinical Toxicology 55:2, pages 109-114.
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Sean P. Bush, Anne-Michelle Ruha, Steven A. Seifert, Dawn R. Sollee & Leslie V. Boyer. (2015) In Reply re: “Comparison of F(ab’)2 versus Fab antivenom for Pit Viper Envenomation: A Prospective, Blinded, Multicenter, Randomized Clinical Trial”. Clinical Toxicology 53:4, pages 414-415.
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Denise Fernandez, Fatema Al Ameri & Mark K. Su. (2015) In response to: Comparison of F(ab’)2 versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial. Clinical Toxicology 53:4, pages 413-413.
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