2,371
Views
34
CrossRef citations to date
0
Altmetric
Review

How toxic is ibogaine?

&
Pages 297-302 | Received 20 Oct 2015, Accepted 31 Dec 2015, Published online: 25 Jan 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Sarah Kratina & Leah M. Mayo. (2023) Tripping outside the lines: lessons from observational studies of combination psychedelic use beyond regulated clinical contexts. The American Journal of Drug and Alcohol Abuse 49:5, pages 541-545.
Read now
Benjamin J. Malcolm, Martin Polanco & Joseph P. Barsuglia. (2018) Changes in Withdrawal and Craving Scores in Participants Undergoing Opioid Detoxification Utilizing Ibogaine. Journal of Psychoactive Drugs 50:3, pages 256-265.
Read now
Marieke Henstra, Liza Wong, Abdel Chahbouni, Noortje Swart, Cor Allaart & Ferdi Sombogaard. (2017) Toxicokinetics of ibogaine and noribogaine in a patient with prolonged multiple cardiac arrhythmias after ingestion of internet purchased ibogaine. Clinical Toxicology 55:6, pages 600-602.
Read now

Articles from other publishers (31)

Jennifer M. Mitchell & Brian T. Anderson. (2023) Psychedelic therapies reconsidered: compounds, clinical indications, and cautious optimism. Neuropsychopharmacology 49:1, pages 96-103.
Crossref
Boukandou Mounanga Marlaine Michele & Aboughe Angone Sophie. (2023) A review of the mechanisms involved in the neuroprotection and neurotoxicity of Iboga alkaloids. Pharmacological Research - Natural Products 1, pages 100006.
Crossref
Juliana Mendes Rocha, José A. S. Reis, José Carlos Bouso, Jaime E. C. Hallak & Rafael G. dos Santos. (2023) Identifying setting factors associated with improved ibogaine safety: a systematic review of clinical studies. European Archives of Psychiatry and Clinical Neuroscience 273:7, pages 1527-1542.
Crossref
Jonathan E. Dickinson, Jose Adalberto Dominguez Inzunza, Liliana Perez-Villa, Trevor G. Millar & Abhiram P. Pushparaj. (2023) Case report: Ibogaine reduced severe neuropathic pain associated with a case of brachial plexus nerve root avulsion. Frontiers in Pain Research 4.
Crossref
Jasper A. Heinsbroek, Giuseppe GiannottiJoel BonillaDavid E. OlsonJamie Peters. (2023) Tabernanthalog Reduces Motivation for Heroin and Alcohol in a Polydrug Use Model. Psychedelic Medicine 1:2, pages 111-119.
Crossref
Andrea Mastinu, Margrate Anyanwu, Marinella Carone, Giulia Abate, Sara Anna Bonini, Gregorio Peron, Emanuela Tirelli, Mariachiara Pucci, Giovanni Ribaudo, Erika Oselladore, Marika Premoli, Alessandra Gianoncelli, Daniela Letizia Uberti & Maurizio Memo. (2023) The Bright Side of Psychedelics: Latest Advances and Challenges in Neuropharmacology. International Journal of Molecular Sciences 24:2, pages 1329.
Crossref
Abeed Sarker, Nisha Nataraj, Wesley Siu, Sabrina Li, Christopher M. Jones & Steven A. Sumner. (2022) Concerns among people who use opioids during the COVID-19 pandemic: a natural language processing analysis of social media posts. Substance Abuse Treatment, Prevention, and Policy 17:1.
Crossref
Benjamin G. Hearn, Michael D. Brubaker & George Richardson. (2022) Counselors’ attitudes toward psychedelics and their use in therapy. Journal of Counseling & Development 100:4, pages 364-373.
Crossref
Patrick Köck, Katharina Froelich, Marc Walter, Undine Lang & Kenneth M. Dürsteler. (2022) A systematic literature review of clinical trials and therapeutic applications of ibogaine. Journal of Substance Abuse Treatment 138, pages 108717.
Crossref
Nataliya Vorobyeva & Alena A. Kozlova. (2022) Three Naturally-Occurring Psychedelics and Their Significance in the Treatment of Mental Health Disorders. Frontiers in Pharmacology 13.
Crossref
Margarida L. F. Martins, Paniz Heydari, Wenlong Li, Alejandra Martínez-Chávez, Nikkie Venekamp, Maria C. Lebre, Luc Lucas, Jos H. Beijnen & Alfred H. Schinkel. (2022) Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites. Frontiers in Pharmacology 13.
Crossref
María Eva González-Trujano, Felix Krengel, Ricardo Reyes-Chilpa, Benjamín Villasana-Salazar, José David González-Gómez, Fernando Santos-Valencia, Edgar Urbina-Trejo, Adrián Martínez & David Martínez-Vargas. (2022) Tabernaemontana arborea and ibogaine induce paroxysmal EEG activity in freely moving mice: Involvement of serotonin 5-HT1A receptors. NeuroToxicology 89, pages 79-91.
Crossref
Thomas Knuijver, Arnt Schellekens, Maarten Belgers, Rogier Donders, Toon van Oosteren, Kees Kramers & Robbert Verkes. (2021) Safety of ibogaine administration in detoxification of opioid‐dependent individuals: a descriptive open‐label observational study. Addiction 117:1, pages 118-128.
Crossref
Zineb Ibn Lahmar Andaloussi, Wendy Lauer, Simo S. Zulu, Khalid Taghzouti & Oualid Abboussi. (2021) Acute cannabidiol treatment attenuates ethanol-induced place preference and reduces aggressivity in group-housed male rats. Pharmacology Biochemistry and Behavior 211, pages 173290.
Crossref
Nikola Tatalović, Teodora Vidonja Uzelac, Zorana Oreščanin Dušić, Aleksandra Nikolić-Kokić, Mara Bresjanac & Duško Blagojević. (2021) Ibogaine-Mediated ROS/Antioxidant Elevation in Isolated Rat Uterus Is β-Adrenergic Receptors and KATP Channels Mediated. Antioxidants 10:11, pages 1792.
Crossref
Kristin Waters. (2021) Pharmacologic Similarities and Differences Among Hallucinogens. The Journal of Clinical Pharmacology 61:S2.
Crossref
Flávia Zacouteguy Boos, Núbia Broetto & Roberta Bristot Silvestrin. 2021. Psychology of Substance Abuse. Psychology of Substance Abuse 3 21 .
Michaela Barber, John Gardner, Michael Savic & Adrian Carter. (2020) Ibogaine therapy for addiction: Consumer views from online fora. International Journal of Drug Policy 83, pages 102857.
Crossref
Maja KohekMaurice Ohren, Paul HornbyMiguel Ángel Alcázar‐Córcoles & José Carlos Bouso. (2020) The Ibogaine Experience: A Qualitative Study on the Acute Subjective Effects of Ibogaine. Anthropology of Consciousness 31:1, pages 91-119.
Crossref
James Grogan, Roy Gerona, Jerry W. Snow & Louise Kao. (2019) Ibogaine Consumption With Seizure-Like Episodes, QTc-Prolongation, and Captured Cardiac Dysrhythmias. The Journal of Emergency Medicine 57:4, pages e99-e104.
Crossref
Ana R. Silva, Clara Grosso, Cristina Delerue-Matos & João M. Rocha. (2019) Comprehensive review on the interaction between natural compounds and brain receptors: Benefits and toxicity. European Journal of Medicinal Chemistry 174, pages 87-115.
Crossref
Giuseppe Floresta, Maria Dichiara, Davide Gentile, Orazio Prezzavento, Agostino Marrazzo, Antonio Rescifina & Emanuele Amata. (2019) Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands. International Journal of Molecular Sciences 20:3, pages 488.
Crossref
Petr Vesely, Tibor Stracina, Miroslava Hlavacova, Josef Halamek, Jana Kolarova, Veronika Olejnickova, Veronika Mrkvicova, Hana Paulova & Marie Novakova. (2019) Haloperidol affects coupling between QT and RR intervals in guinea pig isolated heart. Journal of Pharmacological Sciences 139:1, pages 23-28.
Crossref
Esther Blessing, Sanya Virani & John Rotrosen. 2020. Substance Use Disorders. Substance Use Disorders 167 202 .
Kenichi Tamama & Michael J. Lynch. 2020. Substance Use Disorders. Substance Use Disorders 463 502 .
Christian Steinberg & Marc W. Deyell. (2018) Cardiac arrest after ibogaine intoxication. Journal of Arrhythmia 34:4, pages 455-457.
Crossref
John Martin Corkery. 2018. Psychedelic Neuroscience. Psychedelic Neuroscience 217 257 .
Joseph P. Barsuglia, Martin Polanco, Robert Palmer, Benjamin J. Malcolm, Benjamin Kelmendi & Tanya Calvey. 2018. Psychedelic Neuroscience. Psychedelic Neuroscience 121 158 .
Clare Wilkins, Rafael G. dos Santos, Jordi Solá, Marc Aixalá, Pep Cura, Estefanía Moreno, Miguel Ángel Alcázar-Córcoles, Jaime E. C. Hallak & José Carlos Bouso. (2017) Detoxification from methadone using low, repeated, and increasing doses of ibogaine: A case report. Journal of Psychedelic Studies 1:1, pages 29-34.
Crossref
Eduardo Ekman Schenberg, Maria Angélica de Castro Comis, João Felipe Morel Alexandre, Bruno Daniel Rasmussen Chaves, Luís Fernando Tófoli & Dartiu Xavier da Silveira. (2017) Treating drug dependence with the aid of ibogaine: A qualitative study. Journal of Psychedelic Studies 1:1, pages 10-19.
Crossref
Rafael G. dos Santos, José Carlos Bouso & Jaime E. C. Hallak. (2017) The antiaddictive effects of ibogaine: A systematic literature review of human studies. Journal of Psychedelic Studies 1:1, pages 20-28.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.