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Journal of Toxicology: Clinical Toxicology Volume 26, 1988 - Issue 7
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Research Article

Distribution of oral 4-methylpyrazole in the rat: Inhibition of elimination by ethanol

Kenneth E. McMartin Department of Pharmacology Section of Toxicology, Metabolic Alcohol Research Group Louisiana State University Medical Center, Shreveport, Louisiana, 71130-3932
Pages 451-466 | Published online: 25 Sep 2008

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Yvonne E. Lao, Trond Vartdal, Sten Froeyshov, Brian Latimer, Christiane Kvaerner, Marija Mataric, Peter Holm, Siri Foreid, Dag Jacobsen, Kenneth McMartin & Knut Erik Hovda. (2022) Fomepizole dosing during continuous renal replacement therapy – an observational study. Clinical Toxicology 60:4, pages 451-457.
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Rebeca Gracia, Brian Latimer & Kenneth E. McMartin. (2012) Kinetics of fomepizole in pregnant rats. Clinical Toxicology 50:8, pages 743-748.
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Kenneth E. McMartin, C. Simon Sebastian, David Dies & Dag Jacobsen. (2012) Kinetics and metabolism of fomepizole in healthy humans. Clinical Toxicology 50:5, pages 375-383.
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Jeanna Marraffa, Alan Forrest, William Grant, Christine Stork, Kenneth McMartin & Mary Ann Howland. (2008) Oral administration of fomepizole produces similar blood levels as identical intravenous dose. Clinical Toxicology 46:3, pages 181-186.
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Annie St-Pierre, Kannan Krishnan & Robert Tardif. (2005) Characterization of the Metabolic Interaction between Trihalomethanes and Chloroacetic Acids using Rat Liver Microsomes. Journal of Toxicology and Environmental Health, Part A 68:4, pages 287-298.
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Articles from other publishers (9)

Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 1 14 .
Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 2829 2842 .
Kenneth McMartin, Knut Erik Hovda & Dag Jacobsen. 2016. Critical Care Toxicology. Critical Care Toxicology 1 14 .
Mark J. Reimers, Mark E. Hahn & Robert L. Tanguay. (2004) Two Zebrafish Alcohol Dehydrogenases Share Common Ancestry with Mammalian Class I, II, IV, and V Alcohol Dehydrogenase Genes but Have Distinct Functional Characteristics. Journal of Biological Chemistry 279:37, pages 38303-38312.
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Ana Maria Páez, Michael Shannon, Timothy Maher & Lawrence Quang. (2004) Effects of 4-Methylpyrazole on Ethanol Neurobehavioral Toxicity in CD-1 Mice. Academic Emergency Medicine 11:8, pages 820-826.
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Margareta Some, Stefan Svensson, Jan-Olov Höög & Anders Helander. (2000) Studies on the interaction between ethanol and serotonin metabolism in rat, using deuterated ethanol and 4-methylpyrazole. Biochemical Pharmacology 59:4, pages 385-391.
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D. Jacobsen, C. S. Sebastian, D. F. Dies, R. L. Breau, E. G. Spann, S. K. Barron & K. E. McMartin. (2007) Kinetic Interactions Between 4‐Methylpyrazole and Ethanol in Healthy Humans. Alcoholism: Clinical and Experimental Research 20:5, pages 804-809.
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D. Jacobsen, J. Østensen, L. Bredesen, E. Ullstein & K. McMartin. (2016) 4-Methylpyrazole (4-MP) is effectively removed by haemodialysis in the pig model. Human & Experimental Toxicology 15:6, pages 494-496.
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Brigitte Gonthier, André Jeunet & Luc Barret. (1991) Electron spin resonance study of free radicals produced from ethanol and acetaldehyde after exposure to a Fenton system or to brain and liver microsomes. Alcohol 8:5, pages 369-375.
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