673
Views
164
CrossRef citations to date
0
Altmetric
Original Article

Enhanced tendon healing with GDF 5 and 6

&
Pages 51-54 | Received 30 May 1998, Accepted 13 Nov 1998, Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Stephen P. Berasi, Usha Varadarajan, Joanne Archambault, Michael Cain, Tatyana A. Souza, Abe Abouzeid, Jian Li, Christopher T. Brown, Andrew J. Dorner, Howard J. Seeherman & Scott A. Jelinsky. (2011) Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities. Growth Factors 29:4, pages 128-139.
Read now
Thomas C. Keller, MaCalus V. Hogan, Girish Kesturu, Roshan James, Gary Balian & A. Bobby Chhabra. (2011) Growth/differentiation factor-5 modulates the synthesis and expression of extracellular matrix and cell-adhesion-related molecules of rat Achilles tendon fibroblasts. Connective Tissue Research 52:4, pages 353-364.
Read now
Joshua S. Dines, Michael B. Cross, David Dines, Christina Pantazopoulos, Han Jo Kim, Pasquale Razzano & Daniel Grande. (2011) In vitro analysis of an rhGDF-5 suture coating process and the effects of rhGDF-5 on rat tendon fibroblasts. Growth Factors 29:1, pages 1-7.
Read now
Meike Haddad-Weber, Patrick Prager, Manuela Kunz, Lothar Seefried, Franz Jakob, Martha M. Murray, Christopher H. Evans, Ulrich Nöth & Andre F. Steinert. (2010) BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells. Cytotherapy 12:4, pages 505-513.
Read now
Yoshinori Sumita, Masaki J. Honda, Minoru Ueda, Izumi Asahina & Hideaki Kagami. (2010) Differential effects of growth differentiation factor-5 on porcine dental papilla- and follicle-derived cells. Growth Factors 28:1, pages 56-65.
Read now
Pernilla Eliasson, Therese Andersson, Jana Kulas, Petra Seemann & Per Aspenberg. (2009) Myostatin in tendon maintenance and repair. Growth Factors 27:4, pages 247-254.
Read now
Markus Rickert, Haili Wang, Peter Wieloch, Helga Lorenz, Eric Steck, Desiderius Sabo & Wiltrud Richter. (2005) Adenovirus-Mediated Gene Transfer of Growth and Differentiation Factor-5 into Tenocytes and the Healing Rat Achilles Tendon. Connective Tissue Research 46:4-5, pages 175-183.
Read now
Per Aspenberg & Olena Virchenko. (2004) Platelet concentrate injection improves Achilles tendon repair in rats. Acta Orthopaedica Scandinavica 75:1, pages 93-99.
Read now
Markus Rickert, Martin Jung, Melki Adiyaman, Wiltrud Richter & Hans Georg Simank. (2001) A Growth and Differentiation Factor-5 (GDF-5)-coated Suture Stimulates Tendon Healing in an Achilles Tendon Model in Rats. Growth Factors 19:2, pages 115-126.
Read now
Randall T. Clark, Tiffany L. Johnson, Benjamin J. Schalet, Lonnie Davis, Veronique Gaschen, Ernst B. Hunziker, Åke Oldberg & Borjana Mikic. (2001) GDF-5 Deficiency in Mice Leads to Disruption of Tail Tendon Form and Function. Connective Tissue Research 42:3, pages 175-186.
Read now

Articles from other publishers (153)

Domiziano Tarantino, Rosita Mottola, Giuseppina Resta, Rossana Gnasso, Stefano Palermi, Bruno Corrado, Felice Sirico, Carlo Ruosi & Rocco Aicale. (2023) Achilles Tendinopathy Pathogenesis and Management: A Narrative Review. International Journal of Environmental Research and Public Health 20:17, pages 6681.
Crossref
Ke Li, Xu Zhang, Dan Wang, Rocky S. Tuan & Dai Fei Elmer Ker. (2023) Synergistic effects of growth factor-based serum-free medium and tendon-like substrate topography on tenogenesis of mesenchymal stem cells. Biomaterials Advances 146, pages 213316.
Crossref
Zhi Jie Li, Qian Qian Yang & You Lang Zhou. (2023) Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing. Stem Cells International 2023, pages 1-14.
Crossref
Yanwei Cao, Zhijun Zhang, Guanyang Song, Qiankun Ni, Tong Zheng & Yue Li. (2022) Biological enhancement methods may be a viable option for ACL arthroscopic primary repair – A systematic review. Orthopaedics & Traumatology: Surgery & Research 108:3, pages 103227.
Crossref
Wataru Morita, Sarah J.B. Snelling, Kim Wheway, Bridget Watkins, Louise Appleton, Richard J. Murphy, Andrew J. Carr & Stephanie G. Dakin. (2021) Comparison of Cellular Responses to TGF-β1 and BMP-2 Between Healthy and Torn Tendons. The American Journal of Sports Medicine 49:7, pages 1892-1903.
Crossref
Dan Wang, Xu Zhang, Shuting Huang, Yang Liu, Bruma Sai-chuen Fu, Kingston King-lun Mak, Anna Maria Blocki, Patrick Shu-hang Yung, Rocky S. Tuan & Dai Fei Elmer Ker. (2021) Engineering multi-tissue units for regenerative Medicine: Bone-tendon-muscle units of the rotator cuff. Biomaterials 272, pages 120789.
Crossref
Jennifer H. Roberts & Jaroslava Halper. 2021. Progress in Heritable Soft Connective Tissue Diseases. Progress in Heritable Soft Connective Tissue Diseases 139 159 .
Thomas Nau & Andreas Teuschl. 2021. Organ Tissue Engineering. Organ Tissue Engineering 489 506 .
Shabnam Javanshir, Fatemeh Younesi Soltani, Gholamreza Dowlati, Abbas Parham & Hojjat Naderi-Meshkin. (2020) Induction of tenogenic differentiation of equine adipose-derived mesenchymal stem cells by platelet-derived growth factor-BB and growth differentiation factor-6. Molecular Biology Reports 47:9, pages 6855-6862.
Crossref
Thomas Nau & Andreas Teuschl. 2020. Organ Tissue Engineering. Organ Tissue Engineering 1 18 .
Héctor Capella-Monsonís, Salomé Guillaumin, Sofia Ribeiro, Stefanie Korntner, Yves Bayon & Dimitrios I. Zeugolis. 2019. Handbook of Tissue Engineering Scaffolds: Volume One. Handbook of Tissue Engineering Scaffolds: Volume One 259 298 .
Graeme P. Whyte, Ignacio Dallo, Katarzyna Herman & Alberto Gobbi. 2019. Complex Knee Ligament Injuries. Complex Knee Ligament Injuries 201 209 .
Piero Volpi & Gian Nicola BisciottiPiero Volpi & Gian Nicola Bisciotti. 2019. Muscle Injury in the Athlete. Muscle Injury in the Athlete 53 72 .
Alberto Gobbi & Graeme P. Whyte. (2018) Long-term Outcomes of Primary Repair of the Anterior Cruciate Ligament Combined With Biologic Healing Augmentation to Treat Incomplete Tears. The American Journal of Sports Medicine 46:14, pages 3368-3377.
Crossref
Pilar M. de Albornoz, Rocco Aicale, Francisco Forriol & Nicola Maffulli. (2018) Cell Therapies in Tendon, Ligament, and Musculoskeletal System Repair. Sports Medicine and Arthroscopy Review 26:2, pages 48-58.
Crossref
Tanujan Thangarajah, Anita Sanghani-Kerai, Frederick Henshaw, Simon M. Lambert, Catherine J. Pendegrass & Gordon W. Blunn. (2017) Application of a Demineralized Cortical Bone Matrix and Bone Marrow–Derived Mesenchymal Stem Cells in a Model of Chronic Rotator Cuff Degeneration. The American Journal of Sports Medicine 46:1, pages 98-108.
Crossref
Alberto Gobbi, Georgios Karnatzikos & Abhishek Mudhigere. 2018. The Anterior Cruciate Ligament. The Anterior Cruciate Ligament 382 385.e2 .
Weronika Zarychta-Wiśniewska, Anna Burdzinska, Agnieszka Kulesza, Kamila Gala, Beata Kaleta, Katarzyna Zielniok, Katarzyna Siennicka, Marek Sabat & Leszek Paczek. (2017) Bmp-12 activates tenogenic pathway in human adipose stem cells and affects their immunomodulatory and secretory properties. BMC Cell Biology 18:1.
Crossref
T.K.H. Teh & J.C.H. Goh. 2017. Comprehensive Biomaterials II. Comprehensive Biomaterials II 194 215 .
Graeme P. Whyte, Alberto Gobbi & Dawid Szwedowski. 2017. Bio-orthopaedics. Bio-orthopaedics 665 670 .
Alberto Gobbi & Graeme P. Whyte. 2017. Bio-orthopaedics. Bio-orthopaedics 325 335 .
Alberto Gobbi & Graeme P. Whyte. 2017. Bio-orthopaedics. Bio-orthopaedics 313 324 .
Alberto Gobbi, Graeme P. Whyte & Georgios Karnatzikos. 2017. Controversies in the Technical Aspects of ACL Reconstruction. Controversies in the Technical Aspects of ACL Reconstruction 135 144 .
Ian R. Sigal, Daniel A. Grande, David M. Dines, Joshua Dines & Mark Drakos. (2016) Biologic and Tissue Engineering Strategies for Tendon Repair. Regenerative Engineering and Translational Medicine 2:3-4, pages 107-125.
Crossref
Burak Kaymaz, Umut Hatay G?lge, Gulzade Ozyalvacl?Erkam K?m?rc?Ferdi Goksel, Musa Ugur Mermerkaya & Mahmut Nedim Doral. (2015) Effects of boric acid on the healing of Achilles tendons of rats. Knee Surgery, Sports Traumatology, Arthroscopy 24:12, pages 3738-3744.
Crossref
Gian Nicola Bisciotti & Piero Volpi. 2016. The Lower Limb Tendinopathies. The Lower Limb Tendinopathies 21 40 .
Jon-Michael E. Caldwell, Xinzhi Zhang, Helen H. Lu & William N. Levine. 2016. Elite Techniques in Shoulder Arthroscopy. Elite Techniques in Shoulder Arthroscopy 193 210 .
Siddharth Banka, Stuart A Cain, Sabrya Carim, Sarah B Daly, Jill E Urquhart, G?nhan Erdem, Jade Harris, Michelle Bottomley, Dian Donnai, Bronwyn Kerr, Helen Kingston, Andreas Superti-Furga, Sheila Unger, Holly Ennis, Jane Worthington, Ariane L Herrick, Catherine L R Merry, Wyatt W Yue, Cay M Kielty & William G Newman. (2015) Leri?s pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis . Annals of the Rheumatic Diseases 74:6, pages 1249-1256.
Crossref
Alberto Gobbi, Dnyanesh G. Lad, Georgios Karnatzikos & Sukeshrao Sankineni. 2015. Sports Injuries. Sports Injuries 1369 1376 .
Joseph D. Lamplot, Michael Angeline, Jovito Angeles, Maureen Beederman, Eric Wagner, Farbod Rastegar, Bryan Scott, Christian Skjong, Daniel Mass, Richard Kang, Sherwin Ho & Lewis L. Shi. (2014) Distinct Effects of Platelet-Rich Plasma and BMP13 on Rotator Cuff Tendon Injury Healing in a Rat Model. The American Journal of Sports Medicine 42:12, pages 2877-2887.
Crossref
Chung-Hsun Chang, Wen-Chung Tsai, Ya-Hui Hsu & Jong-Hwei Pang. (2014) Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts. Molecules 19:11, pages 19066-19077.
Crossref
Yasuhiro Ozasa, Anne Gingery, Andrew R. Thoreson, Kai-Nan An, Chunfeng Zhao & Peter C. Amadio. (2014) A Comparative Study of the Effects of Growth and Differentiation Factor 5 on Muscle-Derived Stem Cells and Bone Marrow Stromal Cells in an In Vitro Tendon Healing Model. The Journal of Hand Surgery 39:9, pages 1706-1713.
Crossref
Sys Hasslund, Tulin Dadali, Michael Ulrich-Vinther, Kjeld Søballe, Edward M Schwarz & Hani A Awad. (2014) Freeze-dried allograft-mediated gene or protein delivery of growth and differentiation factor 5 reduces reconstructed murine flexor tendon adhesions. Journal of Tissue Engineering 5, pages 204173141452873.
Crossref
O. A. Branford, B. R. Klass, A. O. Grobbelaar & K. J. Rolfe. (2013) The growth factors involved in flexor tendon repair and adhesion formation. Journal of Hand Surgery (European Volume) 39:1, pages 60-70.
Crossref
Jaroslava Halper. 2014. Progress in Heritable Soft Connective Tissue Diseases. Progress in Heritable Soft Connective Tissue Diseases 59 76 .
Zafar Ahmad, Fran Henson, John Wardale, Ali Noorani, Graham Tytherleigh-Strong & Neil Rushton. (2013) Review Article: Regenerative Techniques for Repair of Rotator Cuff Tears. Journal of Orthopaedic Surgery 21:2, pages 226-231.
Crossref
Qiang Zhang, Heng?an Ge, Jiaojiao Zhou & Biao Cheng. (2013) Are Platelet-Rich Products Necessary during the Arthroscopic Repair of Full-Thickness Rotator Cuff Tears: A Meta-Analysis. PLoS ONE 8:7, pages e69731.
Crossref
Alberto Gobbi, Georgios Karnatzikos, Sukesh R. Sankineani & Massimo Petrera. (2013) Biological Augmentation of ACL Refixation in Partial Lesions in a Group of Athletes. Techniques in Orthopaedics 28:2, pages 180-184.
Crossref
Julia Zimmer, Elisa Degenkolbe, Britt Wildemann & Petra Seemann. 2013. Bioinformatics. Bioinformatics 1252 1281 .
Julia Zimmer, Elisa Degenkolbe, Britt Wildemann & Petra Seemann. 2013. Medical Advancements in Aging and Regenerative Technologies. Medical Advancements in Aging and Regenerative Technologies 1 30 .
Subhash C Juneja. (2013) Cellular distribution and gene expression profile during flexor tendon graft repair: A novel tissue engineering approach * . Journal of Tissue Engineering 4, pages 204173141349274.
Crossref
Alberto Gobbi, Dnyanesh G. Lad, Georgios Karnatzikos & Sukeshrao Sankineni. 2015. Sports Injuries. Sports Injuries 1 10 .
Mark Young & Michael R. Doran. 2013. Mesenchymal Stem Cell Therapy. Mesenchymal Stem Cell Therapy 117 144 .
Jennifer Lei & Johnna S. Temenoff. 2013. Structural Interfaces and Attachments in Biology. Structural Interfaces and Attachments in Biology 323 349 .
Jonathan B. Albilia, Howard C. Tenenbaum, Cameron M. L. Clokie, David R. Walt, Gerald I. Baker, David J. Psutka, David Backstein & Sean A. F. Peel. (2012) Serum levels of BMP‐2, 4, 7 and AHSG in patients with degenerative joint disease requiring total arthroplasty of the hip and temporomandibular joints. Journal of Orthopaedic Research 31:1, pages 44-52.
Crossref
Masanori Hayashi, Chunfeng Zhao, Kai-Nan An & Peter C. Amadio. (2012) Cell Migration after Synovium Graft Interposition at Tendon Repair Site. HAND 7:4, pages 374-379.
Crossref
Gadi Pelled, Jess G. Snedeker, Ayelet Ben-Arav, Samuela Rigozzi, Yoram Zilberman, Nadav Kimelman-Bleich, Zulma Gazit, Ralph Müller & Dan Gazit. (2012) Smad8/BMP2-engineered mesenchymal stem cells induce accelerated recovery of the biomechanical properties of the achilles tendon. Journal of Orthopaedic Research 30:12, pages 1932-1939.
Crossref
Hamid Namazi. (2012) Letter Regarding ?Effect of Platelet-Rich Plasma With Fibrin Matrix on Healing of Intrasynovial Flexor Tendons?. The Journal of Hand Surgery 37:10, pages 2197-2198.
Crossref
Michael E. Angeline & Scott A. Rodeo. (2012) Biologics in the Management of Rotator Cuff Surgery. Clinics in Sports Medicine 31:4, pages 645-663.
Crossref
Bryan T. Leek, James P. Tasto, Lisa M. Tibor, Robert M. Healey, Anthony Freemont, Michael S. Linn, Derek E. Chase & David Amiel. (2012) Augmentation of Tendon Healing With Butyric Acid–Impregnated Sutures. The American Journal of Sports Medicine 40:8, pages 1762-1771.
Crossref
Christian Isaac, Burhan Gharaibeh, Michelle Witt, Vonda J. Wright & Johnny Huard. (2012) Biologic approaches to enhance rotator cuff healing after injury. Journal of Shoulder and Elbow Surgery 21:2, pages 181-190.
Crossref
Asheesh Bedi, Travis Maak, Christopher Walsh, Scott A. Rodeo, Dan Grande, David M. Dines & Joshua S. Dines. (2012) Cytokines in rotator cuff degeneration and repair. Journal of Shoulder and Elbow Surgery 21:2, pages 218-227.
Crossref
Sik-Loo Tan, Raja Elina Ahmad, Tunku Sara Ahmad, Azhar M. Merican, Azlina A. Abbas, Wuey Min Ng & Tunku Kamarul. (2012) Effect of Growth Differentiation Factor 5 on the Proliferation and Tenogenic Differentiation Potential of Human Mesenchymal Stem Cells in vitro. Cells Tissues Organs 196:4, pages 325-338.
Crossref
Chuan Hao Chen, Ya Fang Wu & Jin Bo Tang. 2012. Tendon Surgery of the Hand. Tendon Surgery of the Hand e26 e33 .
Peter C. Amadio. 2012. Tendon Surgery of the Hand. Tendon Surgery of the Hand 16 23 .
Anna L. Stevens, Burhan Gharaibeh, Kurt R. Weiss, Freddie H. Fu & Johnny Huard. 2012. Insall &amp Scott Surgery of the Knee. Insall &amp Scott Surgery of the Knee e4-1 e4-31 .
Lawrence V. Gulotta & Scott A. Rodeo. (2010) Emerging Ideas: Evaluation of Stem Cells Genetically Modified with Scleraxis to Improve Rotator Cuff Healing. Clinical Orthopaedics and Related Research® 469:10, pages 2977-2980.
Crossref
Scott A. Jelinsky, Li Li, Debra Ellis, Joanne Archambault, Jian Li, Michael St. Andre, Carl Morris & Howard Seeherman. (2011) Treatment with rhBMP12 or rhBMP13 increase the rate and the quality of rat Achilles tendon repair. Journal of Orthopaedic Research 29:10, pages 1604-1612.
Crossref
P. P. Y. Lui, Y. F. Rui, M. Ni & K. M. Chan. (2011) Tenogenic differentiation of stem cells for tendon repair-what is the current evidence?. Journal of Tissue Engineering and Regenerative Medicine 5:8, pages e144-e163.
Crossref
M. Hayashi, C. Zhao, K.-N. An & P. C. Amadio. (2017) The effects of growth and differentiation factor 5 on bone marrow stromal cell transplants in an in vitro tendon healing model. Journal of Hand Surgery (European Volume) 36:4, pages 271-279.
Crossref
Chung-Hsun Chang, Wen-Chung Tsai, Miao-Sui Lin, Ya-Hui Hsu & Jong-Hwei Su Pang. (2011) The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology 110:3, pages 774-780.
Crossref
Stefan Buchmann, Lars Walz, Gunther H. Sandmann, Henriette Hoppe, Knut Beitzel, Gabriele Wexel, Achim Battmann, Stephan Vogt, Stefan Hinterwimmer & Andreas B. Imhoff. (2010) Rotator cuff changes in a full thickness tear rat model: verification of the optimal time interval until reconstruction for comparison to the healing process of chronic lesions in humans. Archives of Orthopaedic and Trauma Surgery 131:3, pages 429-435.
Crossref
Macalus Hogan, Kesturu Girish, Roshan James, Gary Balian, Shepard Hurwitz & A. B. Chhabra. (2011) Growth differentiation factor-5 regulation of extracellular matrix gene expression in murine tendon fibroblasts. Journal of Tissue Engineering and Regenerative Medicine 5:3, pages 191-200.
Crossref
Graham Riley. 2011. Rheumatology. Rheumatology 83 89.e1 .
Peter C. Amadio. 2011. Rehabilitation of the Hand and Upper Extremity, 2-Volume Set. Rehabilitation of the Hand and Upper Extremity, 2-Volume Set 439 444.e5 .
Naofumi Okamoto, Taketoshi Kushida, Kenichi Oe, Masayuki Umeda, Susumu Ikehara & Hirokazu Iida. (2010) Treating Achilles Tendon Rupture in Rats with Bone-Marrow-Cell Transplantation Therapy. Journal of Bone and Joint Surgery 92:17, pages 2776-2784.
Crossref
R. Frank HennIIIIII, Christina E. Kuo, Michael W. Kessler, Pasquale Razzano, Daniel P. Grande & Scott W. Wolfe. (2010) Augmentation of Zone II Flexor Tendon Repair Using Growth Differentiation Factor 5 in a Rabbit Model. The Journal of Hand Surgery 35:11, pages 1825-1832.
Crossref
Haron Obaid & David Connell. (2010) Cell Therapy in Tendon Disorders. The American Journal of Sports Medicine 38:10, pages 2123-2132.
Crossref
Andrew ParkMaCalus V. HoganGirish S. KesturuRoshan JamesGary BalianAbhinav Bobby Chhabra. (2010) Adipose-Derived Mesenchymal Stem Cells Treated with Growth Differentiation Factor-5 Express Tendon-Specific Markers. Tissue Engineering Part A 16:9, pages 2941-2951.
Crossref
Borjana Mikic, Kerri Rossmeier & LouAnn Bierwert. (2009) Sexual dimorphism in the effect of GDF‐6 deficiency on murine tendon. Journal of Orthopaedic Research 27:12, pages 1603-1611.
Crossref
Borjana Mikic, Kerri Rossmeier & Louann Bierwert. (2009) Identification of a Tendon Phenotype in GDF6 Deficient Mice. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology 292:3, pages 396-400.
Crossref
P.C. Bessa, M.T. Cerqueira, T. Rada, M.E. Gomes, N.M. Neves, A. Nobre, R.L. Reis & M. Casal. (2009) Expression, purification and osteogenic bioactivity of recombinant human BMP-4, -9, -10, -11 and -14. Protein Expression and Purification 63:2, pages 89-94.
Crossref
Suna Ömeroğlu, Tuncay Peker, Nurten Türközkan & Hakan Ömeroğlu. (2008) High-dose vitamin C supplementation accelerates the Achilles tendon healing in healthy rats. Archives of Orthopaedic and Trauma Surgery 129:2, pages 281-286.
Crossref
Laurent Dupoirieux, Jens Pohl, Michael Hanke & Didier Pourquier. (2009) A preliminary report on the effect of dimeric rhGDF-5 and its monomeric form rhGDF-5C465A on bone healing of rat cranial defects. Journal of Cranio-Maxillofacial Surgery 37:1, pages 30-35.
Crossref
Lawrence V. Gulotta & Scott A. Rodeo. (2009) Growth Factors for Rotator Cuff Repair. Clinics in Sports Medicine 28:1, pages 13-23.
Crossref
Jeremy J. Lim & Johnna S. Temenoff. 2009. Fundamentals of Tissue Engineering and Regenerative Medicine. Fundamentals of Tissue Engineering and Regenerative Medicine 255 269 .
Shelly E. Sakiyama-Elbert, Rosalina Das, Richard H. Gelberman, Fredrick Harwood, David Amiel & Stavros Thomopoulos. (2008) Controlled-Release Kinetics and Biologic Activity of Platelet-Derived Growth Factor-BB for Use in Flexor Tendon Repair. The Journal of Hand Surgery 33:9, pages 1548-1557.
Crossref
Howard J Seeherman, Joanne M Archambault, Scott A Rodeo, A Simon Turner, Lisa Zekas, Darren D?Augusta, X Jian Li, Erica Smith & John M Wozney. (2008) rhBMP-12 Accelerates Healing of Rotator Cuff Repairs in a Sheep Model. The Journal of Bone and Joint Surgery-American Volume 90:10, pages 2206-2219.
Crossref
LeAnn M. Dourte, Andrew F. Kuntz & Louis J. Soslowsky. (2008) Twenty‐five years of tendon and ligament research. Journal of Orthopaedic Research 26:10, pages 1297-1305.
Crossref
Lee-Chuan C. Yeh, Alicia D. Tsai & John C. Lee. (2008) Bone morphogenetic protein-7 regulates differentially the mRNA expression of bone morphogenetic proteins and their receptors in rat achilles and patellar tendon cell cultures. Journal of Cellular Biochemistry 104:6, pages 2107-2122.
Crossref
Eugene Farng, Alfonso R. Urdaneta, David Barba, Sean Esmende & David R. McAllister. (2008) The Effects of GDF-5 and Uniaxial Strain on Mesenchymal Stem Cells in 3-D Culture. Clinical Orthopaedics and Related Research 466:8, pages 1930-1937.
Crossref
Pernilla Eliasson, Anna Fahlgren & Per Aspenberg. (2008) Mechanical Load and BMP Signaling During Tendon Repair: A Role for Follistatin?. Clinical Orthopaedics and Related Research 466:7, pages 1592-1597.
Crossref
Borjana Mikic, Rachel Entwistle, Kerri Rossmeier & LouAnn Bierwert. (2008) Effect of GDF‐7 deficiency on tail tendon phenotype in mice. Journal of Orthopaedic Research 26:6, pages 834-839.
Crossref
Sys Hasslund, Justin A. Jacobson, Tulin Dadali, Patrick Basile, Michael Ulrich‐Vinther, Kjeld Søballe, Edward M. Schwarz, Regis J. O'Keefe, David J. Mitten & Hani A. Awad. (2008) Adhesions in a murine flexor tendon graft model: Autograft versus allograft reconstruction. Journal of Orthopaedic Research 26:6, pages 824-833.
Crossref
David Kovacevic & Scott A. Rodeo. (2008) Biological Augmentation of Rotator Cuff Tendon Repair. Clinical Orthopaedics & Related Research 466:3, pages 622-633.
Crossref
Hadi Aslan, Nadav Kimelman-Bleich, Gadi Pelled & Dan Gazit. (2008) Molecular targets for tendon neoformation. Journal of Clinical Investigation 118:2, pages 439-444.
Crossref
Per Aspenberg. (2007) Stimulation of tendon repair: mechanical loading, GDFs and platelets. A mini-review. International Orthopaedics 31:6, pages 783-789.
Crossref
Andrea Hoffmann & Gerhard Gross. (2007) Tendon and ligament engineering in the adult organism: mesenchymal stem cells and gene-therapeutic approaches. International Orthopaedics 31:6, pages 791-797.
Crossref
Lucy E. Richardson, Jayesh Dudhia, Peter D. Clegg & Roger Smith. (2007) Stem cells in veterinary medicine – attempts at regenerating equine tendon after injury. Trends in Biotechnology 25:9, pages 409-416.
Crossref
Scott A. Rodeo. (2007) Biologic augmentation of rotator cuff tendon repair. Journal of Shoulder and Elbow Surgery 16:5, pages S191-S197.
Crossref
Joshua S. Dines, Daniel A. Grande & David M. Dines. (2007) Tissue engineering and rotator cuff tendon healing. Journal of Shoulder and Elbow Surgery 16:5, pages S204-S207.
Crossref
Joshua S. Dines, Lawrence Weber, Pasquale Razzano, Rita Prajapati, Mark Timmer, Steven Bowman, Lawrence Bonasser, David M. Dines & Daniel P. Grande. (2007) The effect of growth differentiation factor-5–coated sutures on tendon repair in a rat model. Journal of Shoulder and Elbow Surgery 16:5, pages S215-S221.
Crossref
J.M.G.Th. JennerF. van EijkD.B.F. SarisW.J. WillemsW.J.A. DhertLaura B. Creemers. (2007) Effect of Transforming Growth Factor-Beta and Growth Differentiation Factor-5 on Proliferation and Matrix Production by Human Bone Marrow Stromal Cells Cultured on Braided Poly Lactic-Co-Glycolic Acid Scaffolds for Ligament Tissue Engineering. Tissue Engineering 13:7, pages 1573-1582.
Crossref
Patrick Bolt, Avnish Neil Clerk, Hue H. Luu, Quan Kang, Jennifer L. Kummer, Zhong-Liang Deng, Kirstina Olson, Frank Primus, Anthony G. Montag, Tong-Chuan He, Rex C. Haydon & Brian C. Toolan. (2007) BMP-14 Gene Therapy Increases Tendon Tensile Strength in a Rat Model of Achilles Tendon Injury. The Journal of Bone & Joint Surgery 89:6, pages 1315-1320.
Crossref
Patrick Bolt, Avnish Neil Clerk, Hue H. Luu, Quan Kang, Jennifer L. Kummer, Zhong-Liang Deng, Kirstina Olson, Frank Primus, Anthony G. Montag, Tong-Chuan He, Rex C. Haydon & Brian C. Toolan. (2007) BMP-14 Gene Therapy Increases Tendon Tensile Strength in a Rat Model of Achilles Tendon Injury. The Journal of Bone and Joint Surgery-American Volume 89:6, pages 1315-1320.
Crossref
MM Ito, K Murase, S Tanaka & T Matsushita. (2016) Promotion of Medial Collateral Ligament Healing Using a High-Voltage Electrical Field. Journal of Orthopaedic Surgery 15:1, pages 22-26.
Crossref
Joshua S. Dines, Daniel A. Grande, Neal ElAttrache & David M. Dines. (2007) Biologics in Shoulder Surgery: Suture Augmentation and Coating to Enhance Tendon Repair. Techniques in Orthopaedics 22:1, pages 20-25.
Crossref
Scott A. Rodeo. (2007) The Role of Bone Morphogenetic Proteins in Rotator Cuff Tendon Repair. Techniques in Orthopaedics 22:1, pages 10-13.
Crossref
Douglas H. Murray, Erik N. Kubiak, Laith M. Jazrawi, Arash Araghi, Frederick Kummer, Mark I. Loebenberg & Joseph D. Zuckerman. (2007) The effect of cartilage-derived morphogenetic protein 2 on initial healing of a rotator cuff defect in a rat model. Journal of Shoulder and Elbow Surgery 16:2, pages 251-254.
Crossref
Matthew B. Werd. (2007) Achilles Tendon Sports Injuries. Journal of the American Podiatric Medical Association 97:1, pages 37-48.
Crossref
Shalaw Fawzi-Grancher, Natalia De Isla, Gilbert Faure, Jean François Stoltz & Sylvaine Muller. (2006) Optimisation of Biochemical Condition and Substrates In Vitro for Tissue Engineering of Ligament. Annals of Biomedical Engineering 34:11, pages 1767-1777.
Crossref
Takanobu Nakase & Hideki Yoshikawa. (2006) Potential roles of bone morphogenetic proteins (BMPs) in skeletal repair and regeneration. Journal of Bone and Mineral Metabolism 24:6, pages 425-433.
Crossref
Deqing Huang, Gary Balian & A. Bobby Chhabra. (2006) Tendon Tissue Engineering and Gene Transfer: The Future of Surgical Treatment. The Journal of Hand Surgery 31:5, pages 693-704.
Crossref
Frank A. Petrigliano, David R. McAllister & Benjamin M. Wu. (2006) Tissue Engineering for Anterior Cruciate Ligament Reconstruction: A Review of Current Strategies. Arthroscopy: The Journal of Arthroscopic & Related Surgery 22:4, pages 441-451.
Crossref
Borjana Mikic, LouAnn Bierwert & Danielle Tsou. (2006) Achilles Tendon characterization in GDF-7 deficient mice. Journal of Orthopaedic Research 24:4, pages 831-841.
Crossref
Tony W. Lin, Luis Cardenas, David L. Glaser & Louis J. Soslowsky. (2006) Tendon healing in interleukin-4 and interleukin-6 knockout mice. Journal of Biomechanics 39:1, pages 61-69.
Crossref
Toshiyuki Tashiro, Hisatada Hiraoka, Yasuko Ikeda, Toshiyuki Ohnuki, Ryuji Suzuki, Takahiro Ochi, Kozo Nakamura & Naoshi Fukui. (2005) Effect of GDF‐5 on ligament healing. Journal of Orthopaedic Research 24:1, pages 71-79.
Crossref
Keith Baar. (2005) New dimensions in tissue engineering: possible models for human physiology. Experimental Physiology 90:6, pages 799-806.
Crossref
Kenton D. Fong, Michael C. Trindade, Zhen Wang, Randall P. Nacamuli, Hung Pham, Tony D. Fang, Hanjoon M. Song, R Lane Smith, Michael T. Longaker & James Chang. (2005) Microarray Analysis of Mechanical Shear Effects on Flexor Tendon Cells. Plastic and Reconstructive Surgery 116:5, pages 1393-1404.
Crossref
Aideen M. Sullivan & Gerard W. O'Keeffe. (2005) The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson's disease treatment. Journal of Anatomy 207:3, pages 219-226.
Crossref
Myron Spector & Changming Guo. 2005. Scaffolding In Tissue Engineering. Scaffolding In Tissue Engineering 385 411 .
Howard Seeherman & John M. Wozney. (2005) Delivery of bone morphogenetic proteins for orthopedic tissue regeneration. Cytokine & Growth Factor Reviews 16:3, pages 329-345.
Crossref
Lee‐Chuan C. Yeh, Alicia D. Tsai & John C. Lee. (2005) Cartilage‐derived morphogenetic proteins induce osteogenic gene expression in the C2C12 mesenchymal cell line. Journal of Cellular Biochemistry 95:1, pages 173-188.
Crossref
Vishal Mehta & Daniel Mass. (2005) The Use of Growth Factors on Tendon Injuries. Journal of Hand Therapy 18:2, pages 87-92.
Crossref
Boris A. Zelle, Christian Lattermann, Anikar Chhabra, Freddie H. Fu & Johnny Huard. (2005) Biological considerations of tendon graft incorporation within the bone tunnel. Operative Techniques in Orthopaedics 15:1, pages 36-42.
Crossref
Vishal Mehta, Quan Kang, Jeffrey Luo, Tong-Chuan He, Rex C. Haydon & Daniel P. Mass. (2005) Characterization of adenovirus-mediated gene transfer in rabbit flexor tendons. The Journal of Hand Surgery 30:1, pages 136-141.
Crossref
Per Renström & Thomas Hach. 2005. Tendon Injuries. Tendon Injuries 70 85 .
Daniel H. Kim, Tae A. Jahng, Tsai-Sheng Fu, Ho-Yeol Zhang & Shannon A. Novak. (2004) Evaluation of HealosMP52 Osteoinductive Bone Graft for Instrumented Lumbar Intertransverse Process Fusion in Sheep. Spine 29:24, pages 2800-2808.
Crossref
Lee‐Chuan C. Yeh, Alicia D. Tsai, Michelle C. Zavala & John C. Lee. (2004) Cartilage‐derived morphogenetic proteins enhance the osteogenic protein‐1‐induced osteoblastic cell differentiation of C2C12 cells. Journal of Cellular Physiology 201:3, pages 401-408.
Crossref
Mehmet Halici, Sinan Karaoglu, Ozlem Canoz, Sevki Kabak & Ali Baktir. (2004) Sodium hyaluronate regulating angiogenesis during Achilles tendon healing. Knee Surgery, Sports Traumatology, Arthroscopy 12:6, pages 562-567.
Crossref
Xudong Li, Brian M. Leo, Gina Beck, Gary Balian & Greg D. Anderson. (2004) Collagen and Proteoglycan Abnormalities in the GDF-5-Deficient Mice and Molecular Changes When Treating Disk Cells With Recombinant Growth Factor. Spine 29:20, pages 2229-2234.
Crossref
Michael J. DeFranco, Kathleen Derwin & Joseph P. Iannotti. (2004) New Therapies in Tendon Reconstruction. Journal of the American Academy of Orthopaedic Surgeons 12:5, pages 298-304.
Crossref
Arnulf Pascher, Andre F. Steinert, Glyn D. Palmer, Oliver Betz, Jean-Noel Gouze, Elvire Gouze, Carmencita Pilapil, Stephen C. Ghivizzani, Christopher H. Evans & Martha Meaney Murray. (2004) Enhanced Repair of the Anterior Cruciate Ligament by in Situ Gene Transfer: Evaluation in an in Vitro Model. Molecular Therapy 10:2, pages 327-336.
Crossref
Tony W. Lin, Luis Cardenas & Louis J. Soslowsky. (2004) Biomechanics of tendon injury and repair. Journal of Biomechanics 37:6, pages 865-877.
Crossref
Martina Lovric-Bencic, Predrag Sikiric, Jadranka S. Hanzevacki, Sven Seiwerth, Dunja Rogic, Vesna Kusec, Gorana Aralica, Pasko Konjevoda, Lovorka Batelja & Alenka B. Blagaic. (2004) Doxorubicine-Congestive Heart Failure-Increased Big Endothelin-1 Plasma Concentration: Reversal by Amlodipine, Losartan, and Gastric Pentadecapeptide BPC157 in Rat and Mouse. Journal of Pharmacological Sciences 95:1, pages 19-26.
Crossref
Frank P. Luyten, Rik Lories, Dirk De Valck, Cosimo De Bari & Francesco Dell’Accio. 2004. Bone Morphogenetic Proteins: Regeneration of Bone and Beyond. Bone Morphogenetic Proteins: Regeneration of Bone and Beyond 187 212 .
Toshiaki Nakamura, Matsuo Yamamoto, Masato Tamura & Yuichi Izumi. (2003) Effects of growth/differentiation factor-5 on human periodontal ligament cells. Journal of Periodontal Research 38:6, pages 597-605.
Crossref
M. Staresinic, B. Sebecic, L. Patrlj, S. Jadrijevic, S. Suknaic, D. Perovic, G. Aralica, N. Zarkovic, S. Borovic, M. Srdjak, K. Hajdarevic, M. Kopljar, L. Batelja, A. Boban‐Blagaic, I. Turcic, T. Anic, S. Seiwerth & P. Sikiric. (2006) Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth. Journal of Orthopaedic Research 21:6, pages 976-983.
Crossref
Alicia D. Tsai, Lee‐Chuan C. Yeh & John C. Lee. (2003) Effects of osteogenic protein‐1 (OP‐1, BMP‐7) on gene expression in cultured medial collateral ligament cells. Journal of Cellular Biochemistry 90:4, pages 777-791.
Crossref
A. Chhabra, D. Tsou, R. T. Clark, V. Gaschen, E. B. Hunziker & B. Mikic. (2006) GDF‐5 deficiency in mice delays Achilles tendon healing. Journal of Orthopaedic Research 21:5, pages 826-835.
Crossref
James Cho-Hong Goh, Hong-Wei Ouyang, Swee-Hin Teoh, Casey K.C. Chan & Eng-Hin Lee. (2003) Tissue-Engineering Approach to the Repair and Regeneration of Tendons and Ligaments. Tissue Engineering 9:supplement 1, pages 31-44.
Crossref
Hiroya Kuniyasu, Yukito Hirose, Morio Ochi, Akihiro Yajima, Kunihiko Sakaguchi, Masaru Murata & Jens Pohl. (2003) Bone augmentation using rhGDF‐5–collagen composite. Clinical Oral Implants Research 14:4, pages 490-499.
Crossref
Carina Forslund, David Rueger & Per Aspenberg. (2003) A comparative dose–response study of cartilage-derived morphogenetic protein (CDMP)-1, -2 and -3 for tendon healing in rats. Journal of Orthopaedic Research 21:4, pages 617-621.
Crossref
Marc Jayankura, Christophe Boggione, Charlotte Frisén, Olivier Boyer, Pierre Fouret, Gérard Saillant & David Klatzmann. (2003) In situ gene transfer into animal tendons by injection of naked DNA and electrotransfer . The Journal of Gene Medicine 5:7, pages 618-624.
Crossref
Sai Chuen Fu, Yim Ping Wong, Barbara Pui Chan, Hon Man Pau, Yau Chuk Cheuk, Kwong Man Lee & Kai-Ming Chan. (2003) The roles of bone morphogenetic protein (BMP) 12 in stimulating the proliferation and matrix production of human patellar tendon fibroblasts. Life Sciences 72:26, pages 2965-2974.
Crossref
Carina Forslund & Per Aspenberg. (2017) Improved Healing of Transected Rabbit Achilles Tendon after a Single Injection of Cartilage-Derived Morphogenetic Protein-2. The American Journal of Sports Medicine 31:4, pages 555-559.
Crossref
K. SenaY. MorotomeO. BabaT. TerashimaY. TakanoI. Ishikawa. (2016) Gene Expression of Growth Differentiation Factors in the Developing Periodontium of Rat Molars. Journal of Dental Research 82:3, pages 166-171.
Crossref
M. Rickert, M. Jung, M. Adiyaman, W. Richter & H. G. Simank. 2003. Tissue Engineering. Tissue Engineering 177 188 .
Carina Forslund & Per Aspenberg. (2006) CDMP‐2 induces bone or tendon‐like tissue depending on mechanical stimulation. Journal of Orthopaedic Research 20:6, pages 1170-1174.
Crossref
T. J. Ivie, R. C. Bray & P. T. Salo. (2006) Denervation impairs healing of the rabbit medial collateral ligament. Journal of Orthopaedic Research 20:5, pages 990-995.
Crossref
Tord D. Alden, Peter Varady, David F. Kallmes, John A. JaneJr.,Jr., & Gregory A. Helm. (2002) Bone Morphogenetic Protein Gene Therapy. Spine 27:Supplement, pages S87-S93.
Crossref
Takanobu Nakase, Kazuomi Sugamoto, Takashi Miyamoto, Noriyuki Tsumaki, Frank P. Luyten, Hiroaki Inui, Akira Myoui, Tetsuya Tomita & Hideki Yoshikawa. (2002) Activation of Cartilage-Derived Morphogenetic Protein-1 in Torn Rotator Cuff. Clinical Orthopaedics and Related Research 399, pages 140-145.
Crossref
B Mikic, T.C Battaglia, E.A Taylor & R.T Clark. (2002) The effect of growth/differentiation factor-5 deficiency on femoral composition and mechanical behavior in mice. Bone 30:5, pages 733-737.
Crossref
Anthony A. Schepsis, Hugh Jones & Andrew L. Haas. (2017) Achilles Tendon Disorders in Athletes. The American Journal of Sports Medicine 30:2, pages 287-305.
Crossref
K. P. Spindler, J. M. Dawson, G. C. Stahlman, J. M. Davidson & L. B. Nanney. (2006) Collagen expression and biomechanical response to human recombinant transforming growth factor beta (rhTGF‐β2) in the healing rabbit MCL. Journal of Orthopaedic Research 20:2, pages 318-324.
Crossref
Frank P. Luyten, Rik Lories, Dirk De Valck, Cosimo De Bari & Francesco Dell’Accio. 2002. Bone Morphogenetic Proteins. Bone Morphogenetic Proteins 223 248 .
V. Denaro, F. Forriol, A. Di Martino, L. Denaro, R. Papalia & G. Caione. (2001) Effect of a mucolytic agent on collagen fibres: An optical and polarized light histological study. European Journal of Orthopaedic Surgery & Traumatology 11:4, pages 209-212.
Crossref
Gregory A. Helm, Jin Zhong Li, Tord D. Alden, Sarah B. Hudson, Elisa J. Beres, Mary Cunningham, Mark M. Mikkelsen, Debra D. Pittman, Kelvin M. Kerns & David F. Kallmes. (2001) A light and electron microscopic study of ectopic tendon and ligament formation induced by bone morphogenetic protein—13 adenoviral gene therapy. Journal of Neurosurgery 95:2, pages 298-307.
Crossref
Borjana Mikic, Benjamin J. Schalet, Randall T. Clark, Veronique Gaschen & Ernst B. Hunziker. (2006) GDF‐5 deficiency in mice alters the ultrastructure, mechanical properties and composition of the Achilles tendon. Journal of Orthopaedic Research 19:3, pages 365-371.
Crossref
Aaron Daluiski, Soyun E. Yi & Karen M. Lyons. (2001) The molecular control of upper extremity development: Implications for congenital hand anomalies. The Journal of Hand Surgery 26:1, pages 8-22.
Crossref
Fabio Quatra, Michele R. Colonna & Maria Rosaria Galeano. (2000) Exogenous Growth Factors and Cytokines in Tendon Surgery. Plastic & Reconstructive Surgery 106:2, pages 502.
Crossref
Gregory A. Helm, Tord D. Alden, Jason P. Sheehan & David Kallmes. (2000) Bone Morphogenetic Proteins and Bone Morphogenetic Protein Gene Therapy in Neurological Surgery: A Review. Neurosurgery 46:5, pages 1213-1222.
Crossref
Gregory A. Helm, Jin Zhong Li, Tord D. Alden, Sarah A. Hudson, Elisa J. Beres, Mary Cunningham, Mark M. Mikkelsen, Debra D. Pittman, Kelvin M. Kerns & David F. Kallmes. (2000) A light and electron microscopic study of ectopic tendon and ligament formation induced by bone morphogenetic protein–13 adenoviral gene therapy. Neurosurgical Focus 8:4, pages 1-8.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.