668
Views
52
CrossRef citations to date
0
Altmetric
REVIEW ARTICLE

Amyotrophic lateral sclerosis: A hormonal condition?

, , , , , & show all
Pages 585-588 | Received 30 Mar 2012, Accepted 20 Jun 2012, Published online: 08 Aug 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Corrado Angelini & Gabriele Siciliano. (2021) An updated review on the role of prescribed exercise in the management of Amyotrophic lateral sclerosis. Expert Review of Neurotherapeutics 21:8, pages 871-879.
Read now
Ruth M. Pfeiffer, Bernd Mayer, Ralph W. Kuncl, David P. Check, Elizabeth K. Cahoon, Donna R. Rivera & D. Michal Freedman. (2020) Identifying potential targets for prevention and treatment of amyotrophic lateral sclerosis based on a screen of medicare prescription drugs. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21:3-4, pages 235-245.
Read now
Stéphane Mathis, Philippe Couratier, Adrien Julian, Jean-Michel Vallat, Philippe Corcia & Gwendal Le Masson. (2017) Management and therapeutic perspectives in amyotrophic lateral sclerosis. Expert Review of Neurotherapeutics 17:3, pages 263-276.
Read now
C. Flaherty, J. Kraft, A. Brothers, M. Harrison, R.S. Legro, A. Manni, C. Yang & Z. Simmons. (2017) The relationship between oestrogen and executive functioning in ALS females with emerging Frontotemporal Lobar Degeneration (FTLD) supports a neuroendocrine model of FTLD attenuation. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 18:1-2, pages 74-85.
Read now
Durdane Aksoy, Betul Cevik, Volkan Solmaz & Semiha Gulsum Kurt. (2014) Clinical, demographic and prognostic features of sporadic amyotrophic lateral sclerosis in Northern Turkey. International Journal of Neuroscience 124:1, pages 68-73.
Read now
Philippe Corcia & Paul H Gordon. (2012) Amyotrophic lateral sclerosis and the clinical potential of dexpramipexole. Therapeutics and Clinical Risk Management 8, pages 359-366.
Read now

Articles from other publishers (46)

Ilaria Martinelli, Andrea Ghezzi, Elisabetta Zucchi, Giulia Gianferrari, Laura Ferri, Cristina Moglia, Umberto Manera, Luca Solero, Rosario Vasta, Antonio Canosa, Maurizio Grassano, Maura Brunetti, Letizia Mazzini, Fabiola De Marchi, Cecilia Simonini, Nicola Fini, Marco Vinceti, Marcello Pinti, Adriano Chiò, Andrea Calvo & Jessica Mandrioli. (2023) Predictors for progression in amyotrophic lateral sclerosis associated to SOD1 mutation: insight from two population-based registries. Journal of Neurology 270:12, pages 6081-6092.
Crossref
Mieke DuMont, Alyssa Agostinis, Kiran Singh, Evan Swan, Yvonne Buttle & Daniela Tropea. (2023) Sex representation in neurodegenerative and psychiatric disorders' preclinical and clinical studies. Neurobiology of Disease 184, pages 106214.
Crossref
Sabrina K. Henne, Markus M. NöthenPDPD & Stefanie Heilmann-Heimbach. (2023) Male-pattern hair loss: Comprehensive identification of the associated genes as a basis for understanding pathophysiology. Medizinische Genetik 35:1, pages 3-14.
Crossref
Xu Chen, Lu Zhou, Can Cui & Jiangwei Sun. 2023. 225 246 .
Alessandra Renzini, Eva Pigna, Marco Rocchi, Alessia Cedola, Giuseppe Gigli, Viviana Moresi & Dario Coletti. (2022) Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice. International Journal of Molecular Sciences 24:1, pages 98.
Crossref
Edoardo Parrella, Vanessa Porrini, Ilaria Scambi, Michele M. Gennari, Cristina Gussago, Oluwamolakun Bankole, Marina Benarese, Raffaella Mariotti & Marina Pizzi. (2022) Synergistic association of resveratrol and histone deacetylase inhibitors as treatment in amyotrophic lateral sclerosis. Frontiers in Pharmacology 13.
Crossref
Belén Proaño, Julia Casani-Cubel, María Benlloch, Ana Rodriguez-Mateos, Esther Navarro-Illana, Jose María Lajara-Romance & Jose Enrique de la Rubia Ortí. (2022) Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?. Biomedicines 10:9, pages 2084.
Crossref
Pascual Torres, Carlos Anerillas, Omar Ramírez-Núñez, Anna Fernàndez, Mario Encinas, Mònica Povedano, Pol Andrés-Benito, Isidre Ferrer, Victòria Ayala, Reinald Pamplona & Manuel Portero-Otín. (2022) A motor neuron disease mouse model reveals a non-canonical profile of senescence biomarkers. Disease Models & Mechanisms 15:8.
Crossref
Subhavi De Silva, Bradley J. Turner & Nirma D. Perera. (2022) Metabolic Dysfunction in Motor Neuron Disease: Shedding Light through the Lens of Autophagy. Metabolites 12:7, pages 574.
Crossref
Emily E. Handley, Laura A. Reale, Jyoti A. Chuckowree, Marcus S. Dyer, Grace L. Barnett, Courtney M. Clark, William Bennett, Tracey C. Dickson & Catherine A. Blizzard. (2022) Estrogen Enhances Dendrite Spine Function and Recovers Deficits in Neuroplasticity in the prpTDP-43A315T Mouse Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology 59:5, pages 2962-2976.
Crossref
Jéssica Barletto de Sousa Barros, Kamilla de Faria Santos, Dhiogo da Cruz Pereira Bento, Leandro do Prado Assunção, Rodrigo da Silva Santos & Angela Adamski da Silva Reis. (2021) Influence of GSTP1 rs1695 polymorphism on survival in male patients’ amyotrophic lateral sclerosis: a genetic association study in Brazilian population. Molecular Biology Reports 49:2, pages 1655-1659.
Crossref
Oluwamolakun Bankole, Ilaria Scambi, Edoardo Parrella, Matilde Muccilli, Roberta Bonafede, Ermanna Turano, Marina Pizzi & Raffaella Mariotti. (2022) Beneficial and Sexually Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice. International Journal of Molecular Sciences 23:3, pages 1047.
Crossref
Phan H. Truong, Peter J. Crouch, James B. W. Hilton, Catriona A. McLean, Roberto Cappai & Giuseppe D. Ciccotosto. (2021) Sex-dependent effects of amyloid precursor-like protein 2 in the SOD1-G37R transgenic mouse model of MND. Cellular and Molecular Life Sciences 78:19-20, pages 6605-6630.
Crossref
Agustina Lara, Iván Esperante, Maria Meyer, Philippe Liere, Noelia Di Giorgio, Michael Schumacher, Rachida Guennoun, Gisella Gargiulo-Monachelli, Alejandro Federico De Nicola & Maria Claudia Gonzalez Deniselle. (2021) Neuroprotective Effects of Testosterone in Male Wobbler Mouse, a Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology 58:5, pages 2088-2106.
Crossref
Jéssica Barletto de Sousa Barros, Kamilla de Faria Santos, Rômulo Morais Azevedo, Rayana Pereira Dantas de Oliveira, Ana Carolina Dourado Leobas, Dhiogo da Cruz Pereira Bento, Rodrigo da Silva Santos & Angela Adamski da Silva Reis. (2021) No association of GSTP1 rs1695 polymorphism with amyotrophic lateral sclerosis: A case-control study in the Brazilian population. PLOS ONE 16:2, pages e0247024.
Crossref
Santosh Kumar Singh & Rajesh Singh. 2021. Obesity and Cancer. Obesity and Cancer 301 338 .
Jodie Watkins, Anshua Ghosh, Amy F. A. Keerie, James J. P. Alix, Richard J. Mead & Jemeen Sreedharan. (2020) Female sex mitigates motor and behavioural phenotypes in TDP-43Q331K knock-in mice. Scientific Reports 10:1.
Crossref
Kátia de Vasconcelos, Acary Souza Bulle Oliveira, Luiz Fernando Portugal Fuchs, Ricardo Santos Simões, Manuel de Jesus Simoes, Manoel João Batista Castello Girão, Jose Maria Soares Júnior & Edmund Chada Baracat. (2020) Action of hormonal therapy in amyotrophic lateral sclerosis: a systematic review. Revista da Associação Médica Brasileira 66:11, pages 1589-1594.
Crossref
Victoria M McLeod, Mathew D F Chiam, Chew L Lau, Thusitha W Rupasinghe, Wah C Boon & Bradley J Turner. (2020) Dysregulation of Steroid Hormone Receptors in Motor Neurons and Glia Associates with Disease Progression in ALS Mice. Endocrinology 161:9.
Crossref
Riccardo Cristofani, Valeria Crippa, Maria Elena Cicardi, Barbara Tedesco, Veronica Ferrari, Marta Chierichetti, Elena Casarotto, Margherita Piccolella, Elio Messi, Mariarita Galbiati, Paola Rusmini & Angelo Poletti. (2020) A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases. Frontiers in Aging Neuroscience 12.
Crossref
Elisabetta Vegeto, Alessandro Villa, Sara Della Torre, Valeria Crippa, Paola Rusmini, Riccardo Cristofani, Mariarita Galbiati, Adriana Maggi & Angelo Poletti. (2020) The Role of Sex and Sex Hormones in Neurodegenerative Diseases. Endocrine Reviews 41:2, pages 273-319.
Crossref
Pascual Torres, Daniel Cacabelos, Jèssica Pairada, Kylynda C Bauer, Jordi Boada, Laia Fontdevila, Chiara Rossi, Monica Povedano, Isidre Ferrer, Reinald Pamplona, B. Brett Finlay, Manuel Portero-Otín & Victòria Ayala. (2019) Gender-Specific Beneficial Effects of Docosahexaenoic Acid Dietary Supplementation in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice. Neurotherapeutics 17:1, pages 269-281.
Crossref
Kátia de Vasconcelos, Acary Souza Bulle Oliveira, Luiz Fernando Portugal Fuchs, Ricardo Santos Simões, Manoel João Batista Castello Girão, Jose Maria Soares Júnior & Edmund Chada Baracat. (2019) Estrogens: possible protection against Amyotrophic Lateral Sclerosis?. Revista da Associação Médica Brasileira 65:5, pages 576-577.
Crossref
Jessica R. Morrice, Cheryl Y. Gregory-Evans & Christopher A. Shaw. (2018) Modeling Environmentally-Induced Motor Neuron Degeneration in Zebrafish. Scientific Reports 8:1.
Crossref
Kevin Mouzat, Nicolas Molinari, Jovana Kantar, Anne Polge, Philippe Corcia, Philippe Couratier, Pierre Clavelou, Raul Juntas-Morales, Nicolas Pageot, Jean -Marc A. Lobaccaro, Cedric Raoul, Serge Lumbroso & William Camu. (2017) Liver X Receptor Genes Variants Modulate ALS Phenotype. Molecular Neurobiology 55:3, pages 1959-1965.
Crossref
XiaoQin Yuan, Bei Cao, Ying Wu, YongPing Chen, QianQian Wei, RuWei Ou, Jing Yang, XuePing Chen, Bi Zhao, Wei Song & HuiFang Shang. (2018) Association analysis of SNP rs11868035 in SREBF1 with sporadic Parkinson’s disease, sporadic amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population. Neuroscience Letters 664, pages 128-132.
Crossref
Marius Heitzer, Sarah Kaiser, Mithila Kanagaratnam, Adib Zendedel, Philipp Hartmann, Cordian Beyer & Sonja Johann. (2016) Administration of 17β-Estradiol Improves Motoneuron Survival and Down-regulates Inflammasome Activation in Male SOD1(G93A) ALS Mice. Molecular Neurobiology 54:10, pages 8429-8443.
Crossref
L. Galán, J. Matías-Guiu, J. A. Matias-Guiu, M. Yáñez, V. Pytel, A. Guerrero-Sola, A. Vela-Souto, J. A. Arranz-Tagarro, U. Gómez-Pinedo & A. G. García. (2017) Cerebrospinal fluid cytotoxicity does not affect survival in amyotrophic lateral sclerosis. Acta Neurologica Scandinavica 136:3, pages 212-216.
Crossref
Valentina Pegoraro, Antonio Merico & Corrado Angelini. (2017) Micro-RNAs in ALS muscle: Differences in gender, age at onset and disease duration. Journal of the Neurological Sciences 380, pages 58-63.
Crossref
Ying-xiao Ji, Mei Zhao, Ya-ling Liu, Li-sha Chen, Peng-li Hao & Can Sun. (2017) Expression of aromatase and estrogen receptors in lumbar motoneurons of mice. Neuroscience Letters 653, pages 7-11.
Crossref
José Manuel Matamala, Thanuja Dharmadasa & Matthew C Kiernan. (2017) Prognostic factors in C9orf72 amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery & Psychiatry 88:4, pages 281.2-281.
Crossref
Angela Rosenbohm, Raphael S. Peter, Siegfried Erhardt, Dorothée Lulé, Dietrich Rothenbacher, Albert C. Ludolph & Gabriele Nagel. (2017) Epidemiology of amyotrophic lateral sclerosis in Southern Germany. Journal of Neurology 264:4, pages 749-757.
Crossref
Delin Ma, Jeffrey M. Shuler, Aishwarya Kumar, Quincy R. Stanford, Sudheer Tungtur, Hiroshi Nishimune & John A. Stanford. (2016) Effects of Tongue Force Training on Bulbar Motor Function in the Female SOD1-G93A Rat Model of Amyotrophic Lateral Sclerosis. Neurorehabilitation and Neural Repair 31:2, pages 147-156.
Crossref
Elizabeth B. Moloney, Barbara Hobo, Fred De Winter & Joost Verhaagen. (2017) Expression of a Mutant SEMA3A Protein with Diminished Signalling Capacity Does Not Alter ALS-Related Motor Decline, or Confer Changes in NMJ Plasticity after BotoxA-Induced Paralysis of Male Gastrocnemic Muscle. PLOS ONE 12:1, pages e0170314.
Crossref
Daniel Cacabelos, Omar Ramírez-Núñez, Ana Belén Granado-Serrano, Pascual Torres, Victòria Ayala, Victoria Moiseeva, Mònica Povedano, Isidre Ferrer, Reinald Pamplona, Manuel Portero-Otin & Jordi Boada. (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathologica Communications 4:1.
Crossref
Zhouwei Xu, Robert David Henderson, Michael David & Pamela Ann McCombe. (2016) Neurofilaments as Biomarkers for Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis. PLOS ONE 11:10, pages e0164625.
Crossref
L. Zubeldia‐Brenner, C. E. Roselli, S. E. Recabarren, M. C. Gonzalez Deniselle & H. E. Lara. (2016) Developmental and Functional Effects of Steroid Hormones on the Neuroendocrine Axis and Spinal Cord. Journal of Neuroendocrinology 28:7.
Crossref
Arianna Palmieri, Giovanni Mento, Vincenzo Calvo, Giorgia Querin, Carla D'Ascenzo, Chiara Volpato, Johann Roland Kleinbub, Patrizia Silvia Bisiacchi & Gianni Sorarù. (2015) Female gender doubles executive dysfunction risk in ALS: a case-control study in 165 patients. Journal of Neurology, Neurosurgery & Psychiatry 86:5, pages 574-579.
Crossref
Tanya Aggarwal, Maria J. Polanco, Chiara Scaramuzzino, Anna Rocchi, Carmelo Milioto, Laura Emionite, Emanuela Ognio, Fabio Sambataro, Mariarita Galbiati, Angelo Poletti & Maria Pennuto. (2014) Androgens affect muscle, motor neuron, and survival in a mouse model of SOD1-related amyotrophic lateral sclerosis. Neurobiology of Aging 35:8, pages 1929-1938.
Crossref
Hatice Uenal, Angela Rosenbohm, Johannes Kufeldt, Patrick Weydt, Katharina Goder, Albert Ludolph, Dietrich Rothenbacher & Gabriele Nagel. (2014) Incidence and Geographical Variation of Amyotrophic Lateral Sclerosis (ALS) in Southern Germany – Completeness of the ALS Registry Swabia. PLoS ONE 9:4, pages e93932.
Crossref
G. M. Gargiulo-Monachelli, D. Campos-Melo, C. A. Droppelmann, B. A. Keller, C. Leystra-Lantz, A. F. De Nicola, M. C. Gonzalez Deniselle, K. Volkening & M. J. Strong. (2014) Expression and cellular localization of the classical progesterone receptor in healthy and amyotrophic lateral sclerosis affected spinal cord. European Journal of Neurology 21:2, pages 273-e11.
Crossref
R. Spataro & V. La Bella. (2014) Paraneoplastic motor neuron disease associated with breast cancer. European Journal of Neurology 21:1, pages e5-e6.
Crossref
Monica Bame, Robert E. Grier, Richard Needleman & William S.A. Brusilow. (2014) Amino Acids as biomarkers in the SOD1G93A mouse model of ALS. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1842:1, pages 79-87.
Crossref
Susan K. BaxterWendy O. BairdSue ThompsonStephen M. BianchiStephen J. WaltersEllen LeeSam H. AhmedzaiAlison ProctorPamela J. ShawChristopher J. McDermott. (2013) The Impact on the Family Carer of Motor Neurone Disease and Intervention with Noninvasive Ventilation. Journal of Palliative Medicine 16:12, pages 1602-1609.
Crossref
Matthew B. Harms & Robert H. Baloh. (2013) Clinical Neurogenetics. Neurologic Clinics 31:4, pages 929-950.
Crossref
E. Fondell, K. C. Fitzgerald, G. J. Falcone, E. J. O'Reilly & A. Ascherio. (2013) Early-Onset Alopecia and Amyotrophic Lateral Sclerosis: A Cohort Study. American Journal of Epidemiology 178:7, pages 1146-1149.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.