971
Views
134
CrossRef citations to date
0
Altmetric
Research Article

Diagnostic timelines and delays in diagnosing amyotrophic lateral sclerosis (ALS)

, , , , , , & show all
Pages 453-456 | Received 24 Dec 2013, Accepted 09 Mar 2014, Published online: 01 Jul 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (19)

Angela Genge & Adriano Chio. (2023) The future of ALS diagnosis and staging: where do we go from here?. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 24:3-4, pages 165-174.
Read now
Stefan Sennfält, Ulf Kläppe, Sebastian Thams, Kristin Samuelsson, Rayomand Press, Fang Fang & Caroline Ingre. (2023) Dying from ALS in Sweden: clinical status, setting, and symptoms. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 24:3-4, pages 237-245.
Read now
Stefan Sennfält, Ulf Kläppe, Sebastian Thams, Kristin Samuelsson, Rayomand Press, Fang Fang & Caroline Ingre. (2023) The path to diagnosis in ALS: delay, referrals, alternate diagnoses, and clinical progression. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 24:1-2, pages 45-53.
Read now
Giacomo Sferruzza, Luca Bosco, Yuri Matteo Falzone, Tommaso Russo, Teuta Domi, Angelo Quattrini, Massimo Filippi & Nilo Riva. (2022) Neurofilament light chain as a biological marker for amyotrophic lateral sclerosis: a meta-analysis study. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 23:5-6, pages 446-457.
Read now
Andrew Hannaford, Steve Vucic, Matthew C Kiernan & Neil G Simon. (2021) Review Article “Spotlight on Ultrasonography in the Diagnosis of Peripheral Nerve Disease: The Evidence to Date”. International Journal of General Medicine 14, pages 4579-4604.
Read now
Ivonne Jericó, Itsaso Elizalde-Beiras, Inmaculada Pagola, Laura Torné, Arkaitz Galbete, Josu Delfrade-Osinaga & Esther Vicente. (2021) Clinical features and incidence trends of amyotrophic lateral sclerosis in Navarre, Spain, 2007–2018: a population-based study. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 22:5-6, pages 401-409.
Read now
Sabrina Paganoni, Fabiola De Marchi, James Chan, Sara K. Thrower, Nathan P. Staff, Neil Datta, Yaz Y. Kisanuki, Vivian Drory, Christina Fournier, Erik P. Pioro, Stephen A. Goutman, Nazem Atassi, Maryangel Jeon, Sarah Caldwell, Timothy Mcdonough, Caroline Gentile, Jianing Liu, Michelle Turner, Carol Denny, Kevin Felice, Misty Green, Stephanie Scarberry, Saad Abu-Saleh, Beatrice Nefussy, Debbie Hastings, Sangri Kim, Blake Swihart, Ximena Arcila-Londono, Daniel S. Newman, Michael Silverman, Angela Genge, Kristiana Salmon, Lauren Elman, Leo Mccluskey, Kelly Almasy, Marc Gotkine, Kimberly Goslin, Arlena Cummings, Eli K. Edwards, Michael Rivner, Kristy Bouchard, Brandy Quarles, Justin Kwan, Matthew Jaffa, Robert Baloh, Peggy Allred, David Walk, Samuel Maiser, Georgios Manousakis, Valerie Ferment, J. Americo M. Fernandes$suffix/text()$suffix/text(), Pariwat Thaisetthawatkul, Deborah Heimes, Melissa Phillips, Laura Sams, Melissa Kahler, Alecia Corcoran, Daniel G. Larriviere, Sadie Chotto & Gracy Juba. (2020) The NEALS primary lateral sclerosis registry. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21:sup1, pages 74-81.
Read now
Hebatallah R. Rashed & Mohamed A. Tork. (2020) Diagnostic delay among ALS patients: Egyptian study. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21:5-6, pages 416-419.
Read now
. (2019) Theme 1 Epidemiology and informatics. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20:sup1, pages 101-113.
Read now
Jaime Raymond, BjÖrn Oskarsson, Paul Mehta & Kevin Horton. (2019) Clinical characteristics of a large cohort of US participants enrolled in the National Amyotrophic Lateral Sclerosis (ALS) Registry, 2010–2015. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20:5-6, pages 413-420.
Read now
Stephen A. Goutman, Masha G. Savelieff, Stacey A. Sakowski & Eva L. Feldman. (2019) Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials. Expert Opinion on Investigational Drugs 28:6, pages 525-543.
Read now
Francesca Palese, Arianna Sartori, Giancarlo Logroscino & Federica Edith Pisa. (2019) Predictors of diagnostic delay in amyotrophic lateral sclerosis: a cohort study based on administrative and electronic medical records data. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20:3-4, pages 176-185.
Read now
. (2018) Theme 5 Epidemiology and informatics. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19:sup1, pages 178-197.
Read now
Anne Hogden, Geraldine Foley, Robert D Henderson, Natalie James & Samar M Aoun. (2017) Amyotrophic lateral sclerosis: improving care with a multidisciplinary approach. Journal of Multidisciplinary Healthcare 10, pages 205-215.
Read now
Robert G. Miller & Stanley H. Appel. (2017) Introduction to supplement: the current status of treatment for ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 18:sup1, pages 1-4.
Read now
Stuart M. Grieve, Parvathi Menon, Mayuresh S. Korgaonkar, Lavier Gomes, Sheryl Foster, Matthew C. Kiernan & Steve Vucic. (2016) Potential structural and functional biomarkers of upper motor neuron dysfunction in ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 17:1-2, pages 85-92.
Read now
. (2015) ALSUntangled No. 30: Methylcobalamin. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 16:7-8, pages 536-539.
Read now
Susana Pinto & Mamede de Carvalho. (2014) Young slow-progressing ALS patients are at higher risk of inappropriate and disease-quickening surgeries. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 15:7-8, pages 621-621.
Read now
Erin N. Smith, Jonghun Lee, Daria Prilutsky, Stephen Zicha, Zemin Wang, Steve Han & Neta Zach. Plasma neurofilament light levels show elevation two years prior to diagnosis of amyotrophic lateral sclerosis in the UK Biobank. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 0:0, pages 1-7.
Read now

Articles from other publishers (115)

Elena Luib, Antonia F. Demleitner, Isabell Cordts, Erica Westenberg, Petra Rau, Dominik Pürner, Bernhard Haller & Paul Lingor. (2023) Reduced tear fluid production in neurological diseases: a cohort study in 708 patients. Journal of Neurology.
Crossref
Elad Yom‐Tov, Indu Navar, Ernest Fraenkel & James D. Berry. (2023) Identifying amyotrophic lateral sclerosis through interactions with an internet search engine. Muscle & Nerve.
Crossref
D. J. L. Stikvoort García, B.T.H.M. Sleutjes, L. J. van Schelven, H. S. Goedee & L. H. van den Berg. (2023) Diagnostic accuracy of nerve excitability and compound muscle action potential scan derived biomarkers in amyotrophic lateral sclerosis. European Journal of Neurology 30:10, pages 3068-3078.
Crossref
Kelly G. Gwathmey, Philippe Corcia, Chris J. McDermott, Angela Genge, Stefan Sennfält, Mamede de Carvalho & Caroline Ingre. (2023) Diagnostic delay in amyotrophic lateral sclerosis. European Journal of Neurology 30:9, pages 2595-2601.
Crossref
Reuven AvidanYaara FainmesserVivian E. Drory, Vera BrilAlon Abraham. (2023) The Sensitivity of Quantitative Sonographic Assessment of Muscle Thickness for Amyotrophic Lateral Sclerosis Diagnosis. Journal of Clinical Neurophysiology 40:6, pages 529-534.
Crossref
Stanisław Maksymowicz & Tomasz Siwek. (2023) Diagnostic odyssey in amyotrophic lateral sclerosis: diagnostic criteria and reality. Neurological Sciences.
Crossref
Cameron G. Thomson, Paul R. Hutchinson & Peter J. Stern. (2023) Misdiagnosis in Amyotrophic Lateral Sclerosis. The Journal of Hand Surgery 48:8, pages 822-826.
Crossref
Silvina Iluț, Adina Stan, Imelda Rahovan, Elian Hapca, Stefan Strilciuc & Dafin Muresanu. (2023) Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview. Balneo and PRM Research Journal 14:Vol.14, no.2, pages 559.
Crossref
Silvina Iluț, Adina Stan, Imelda Rahovan, Elian Hapca, Ioana Zmaranda, Stefan Strilciuc & Dafin F. Muresanu. (2023) Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview. Balneo and PRM Research Journal 14:Vol.14, no.2, pages 559.
Crossref
Priya Treesa Thomas, Manjusha G Warrier, S Arun, B Bhuvaneshwari, Seena Vengalil, Saraswati Nashi, Veeramani Preethish-Kumar, Kiran Polavarapu, Prakashi Rajaram & Atchayaram Nalini. (2022) An individualised psychosocial intervention program for persons with MND/ALS and their families in low resource settings. Chronic Illness 19:2, pages 458-471.
Crossref
Jennifer C Davies, Thanuja Dharmadasa, Alexander G Thompson, Evan C Edmond, Katie Yoganathan, Jiali Gao, Kevin Talbot & Martin R Turner. (2023) Limited value of serum neurofilament light chain in diagnosing amyotrophic lateral sclerosis. Brain Communications 5:3.
Crossref
Maximilian Vidovic, Lars Hendrik Müschen, Svenja Brakemeier, Gerrit Machetanz, Marcel Naumann & Sergio Castro-Gomez. (2023) Current State and Future Directions in the Diagnosis of Amyotrophic Lateral Sclerosis. Cells 12:5, pages 736.
Crossref
Yang-Fan Cheng, Xiao-Jing Gu, Tian-Mi Yang, Qian-Qian Wei, Bei Cao, Yang Zhang, Hui-Fang Shang & Yong-Ping Chen. (2023) Signature of miRNAs derived from the circulating exosomes of patients with amyotrophic lateral sclerosis. Frontiers in Aging Neuroscience 15.
Crossref
Valerie Kiper, Annette Gary & Rebecca Geist. (2023) Navigating ALS. Nursing 53:2, pages 24-30.
Crossref
Maruša Barbo & Metka Ravnik-Glavač. (2023) Extracellular Vesicles as Potential Biomarkers in Amyotrophic Lateral Sclerosis. Genes 14:2, pages 325.
Crossref
Maxim De Schaepdryver, Pegah Masrori, Philip Van Damme & Koen Poesen. (2022) Effect of neurofilament analysis on the diagnostic delay in amyotrophic lateral sclerosis. CNS Neuroscience & Therapeutics 29:1, pages 70-77.
Crossref
Kim A. Staats, David R. Borchelt, Malú Gámez Tansey & James Wymer. (2022) Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis. Molecular Neurodegeneration 17:1.
Crossref
Sara Alquati, Luca Ghirotto, Ludovica De Panfilis, Cristina Autelitano, Elisabetta Bertocchi, Giovanna Artioli, Francesca Sireci, Silvia Tanzi & Simona Sacchi. (2022) Negotiating the Beginning of Care: A Grounded Theory Study of Health Services for Amyotrophic Lateral Sclerosis. Brain Sciences 12:12, pages 1623.
Crossref
Michael Benatar, Volkan Granit, Peter M Andersen, Anne-Laure Grignon, Caroline McHutchison, Stephanie Cosentino, Andrea Malaspina & Joanne Wuu. (2022) Mild motor impairment as prodromal state in amyotrophic lateral sclerosis: a new diagnostic entity. Brain 145:10, pages 3500-3508.
Crossref
Angela Genge, Benjamin Rix Brooks, Björn Oskarsson, Alexander Kalin, Ming Ji, Stephen Apple & Laura Bower. (2022) Analysis of the US Safety Data for Edaravone (Radicava®) From the Third Year After Launch. Drugs in R&D 22:3, pages 205-211.
Crossref
Justin Kwan & Mithila Vullaganti. (2022) Amyotrophic lateral sclerosis mimics. Muscle & Nerve 66:3, pages 240-252.
Crossref
Anjan Bhattarai, Zhaolin Chen, Phyllis Chua, Paul Talman, Susan Mathers, Caron Chapman, James Howe, C. M. Sarah Lee, Yenni Lie, Govinda R. Poudel & Gary F. Egan. (2022) Network diffusion model predicts neurodegeneration in limb-onset Amyotrophic Lateral Sclerosis. PLOS ONE 17:8, pages e0272736.
Crossref
Can Cui, Jiangwei Sun, Kyla A. McKay, Caroline Ingre & Fang Fang. (2022) Medication use and risk of amyotrophic lateral sclerosis—a systematic review. BMC Medicine 20:1.
Crossref
Hugo M. De Oliveira, Matthew Silsby, Stephan R. Jaiser, H. Ming Lai, Nathan Pavey, Matthew C. Kiernan, Tim L. Williams, Steve Vucic & Mark R. Baker. (2022) Electrodiagnostic findings in facial onset sensory motor neuronopathy (FOSMN). Clinical Neurophysiology 140, pages 228-238.
Crossref
Soyoung Kwak. (2022) Pain in amyotrophic lateral sclerosis: a narrative review. Journal of Yeungnam Medical Science 39:3, pages 181-189.
Crossref
Hiroshi Mitsumoto, Edward J. Kasarskis & Zachary Simmons. (2022) Hastening the Diagnosis of Amyotrophic Lateral Sclerosis. Neurology 99:2, pages 60-68.
Crossref
Vinicius Stefani Borghetti, Vívian Pedigone Cintra, Jean de Oliveira Ramos, Vanessa Daccach Marques, Patrícia Toscano Onofre, Victor Augusto Souza Santana, Lua Flora Pereira Bezerra, Pedro José Tomaselli, André Cleriston José dos Santos, Claudia Ferreira da Rosa Sobreira & Wilson Marques Jr. (2022) Misdiagnoses in a Brazilian population with amyotrophic lateral sclerosis. Arquivos de Neuro-Psiquiatria 80:07, pages 676-680.
Crossref
Ton Fang, Goun Je, Peter Pacut, Kiandokht Keyhanian, Jeff Gao & Mehdi Ghasemi. (2022) Gene Therapy in Amyotrophic Lateral Sclerosis. Cells 11:13, pages 2066.
Crossref
Yujiao Yu, Dejiang Pang, Chunyu Li, Xiaojing Gu, Yongping Chen, Ruwei Ou, Qianqian Wei & Huifang Shang. (2022) The expression discrepancy and characteristics of long non-coding RNAs in peripheral blood leukocytes from amyotrophic lateral sclerosis patients. Molecular Neurobiology 59:6, pages 3678-3689.
Crossref
Afaf Shaabi. (2022) Modeling Amyotrophic Lateral Sclerosis Progression: Logic in the Logit. Cureus.
Crossref
Pascal Cintas. 2022. Pathy's Principles and Practice of Geriatric Medicine. Pathy's Principles and Practice of Geriatric Medicine 733 742 .
Giulia Gianferrari, Ilaria Martinelli, Elisabetta Zucchi, Cecilia Simonini, Nicola Fini, Marco Vinceti, Salvatore Ferro, Annalisa Gessani, Elena Canali, Franco Valzania, Elisabetta Sette, Maura Pugliatti, Valeria Tugnoli, Lucia Zinno, Salvatore Stano, Mario Santangelo, Silvia De Pasqua, Emilio Terlizzi, Donata Guidetti, Doriana Medici, Fabrizio Salvi, Rocco Liguori, Veria Vacchiano, Mario Casmiro, Pietro Querzani, Marco Currò Dossi, Alberto Patuelli, Simonetta Morresi, Marco Longoni, Patrizia De Massis, Rita Rinaldi, Annamaria Borghi, Amedeo Amedei & Jessica Mandrioli. (2022) Epidemiological, Clinical and Genetic Features of ALS in the Last Decade: A Prospective Population-Based Study in the Emilia Romagna Region of Italy. Biomedicines 10:4, pages 819.
Crossref
Ilana Heckler & Iswariya Venkataraman. (2022) Phosphorylated neurofilament heavy chain: a potential diagnostic biomarker in amyotrophic lateral sclerosis. Journal of Neurophysiology 127:3, pages 737-745.
Crossref
David Reyes-Leiva, Oriol Dols-Icardo, Sonia Sirisi, Elena Cortés-Vicente, Janina Turon-Sans, Noemi de Luna, Rafael Blesa, Olivia Belbin, Victor Montal, Daniel Alcolea, Juan Fortea, Alberto Lleó, Ricard Rojas-García & Ignacio Illán-Gala. (2022) Pathophysiological Underpinnings of Extra-Motor Neurodegeneration in Amyotrophic Lateral Sclerosis: New Insights From Biomarker Studies. Frontiers in Neurology 12.
Crossref
Miguel A. Rubio, Mireia Herrando-Grabulosa, Roser Velasco, Israel Blasco, Monica Povedano & Xavier Navarro. (2022) TDP-43 Cytoplasmic Translocation in the Skin Fibroblasts of ALS Patients. Cells 11:2, pages 209.
Crossref
Michelle J. Sanfilippo, Mary E. Layshock & Leslie Keniston. (2022) Exploring the association between outcome measures to guide clinical management in patients with amyotrophic lateral sclerosis. Journal of Physical Therapy Science 34:8, pages 532-539.
Crossref
Lauren N. Coffey, Carrie M. Stephan, M.B. Zimmerman, Chyan K. Decker & Katherine D. Mathews. (2021) Diagnostic delay in patients with FKRP-related muscular dystrophy. Neuromuscular Disorders 31:12, pages 1235-1240.
Crossref
Arvin Behzadi, Fani Pujol-Calderón, Anton E. Tjust, Anna Wuolikainen, Kina Höglund, Karin Forsberg, Erik Portelius, Kaj Blennow, Henrik Zetterberg & Peter Munch Andersen. (2021) Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics. Scientific Reports 11:1.
Crossref
Catarina Falcão de Campos, Marta Gromicho, Hilmi Uysal, Julian Grosskreutz, Magdalena Kuzma-Kozakiewicz, Miguel Oliveira Santos, Susana Pinto, Susanne Petri, Michael Swash & Mamede de Carvalho. (2021) Delayed Diagnosis and Diagnostic Pathway of ALS Patients in Portugal: Where Can We Improve?. Frontiers in Neurology 12.
Crossref
Assunta Ingannato, Silvia Bagnoli, Salvatore Mazzeo, Valentina Bessi, Sabrina Matà, Monica Del Mastio, Gemma Lombardi, Camilla Ferrari, Sandro Sorbi & Benedetta Nacmias. (2021) Neurofilament Light Chain and Intermediate HTT Alleles as Combined Biomarkers in Italian ALS Patients. Frontiers in Neuroscience 15.
Crossref
J.F. Vázquez-Costa, M. Martínez-Molina, M. Fernández-Polo, V. Fornés-Ferrer, M. Frasquet-Carrera & T. Sevilla-Mantecón. (2021) Analysis of the diagnostic pathway and delay in patients with amyotrophic lateral sclerosis in the Valencian Community. Neurología (English Edition) 36:7, pages 504-513.
Crossref
J.F. Vázquez-Costa, M. Martínez-Molina, M. Fernández-Polo, V. Fornés-Ferrer, M. Frasquet-Carrera & T. Sevilla-Mantecón. (2021) Análisis del trayecto y retraso diagnóstico de los pacientes con esclerosis lateral amiotrófica en la Comunidad Valenciana. Neurología 36:7, pages 504-513.
Crossref
Steve Vucic, Nathan Pavey, Mouna Haidar, Bradley J. Turner & Matthew C. Kiernan. (2021) Cortical hyperexcitability: Diagnostic and pathogenic biomarker of ALS. Neuroscience Letters 759, pages 136039.
Crossref
Danielle Richards, John A. Morren & Erik P. Pioro. 2021. Amyotrophic Lateral Sclerosis. Amyotrophic Lateral Sclerosis 15 34 .
Hua‐Jun Chen, Zhang‐Yu Zou, Xiao‐Hong Zhang, Jia‐Yan Shi, Nao‐Xin Huang & Yan‐Juan Lin. (2021) Dynamic Changes in Functional Network Connectivity Involving Amyotrophic Lateral Sclerosis and Its Correlation With Disease Severity. Journal of Magnetic Resonance Imaging 54:1, pages 239-248.
Crossref
Luisa Agnello, Tiziana Colletti, Bruna Lo Sasso, Matteo Vidali, Rossella Spataro, Caterina Maria Gambino, Rosaria Vincenza Giglio, Tommaso Piccoli, Giulia Bivona, Vincenzo La Bella & Marcello Ciaccio. (2021) Tau protein as a diagnostic and prognostic biomarker in amyotrophic lateral sclerosis. European Journal of Neurology 28:6, pages 1868-1875.
Crossref
Emily M. Lund, Trisha A. Hostetter, Jeri E. Forster, Claire A. Hoffmire, Kelly A. Stearns‐Yoder, Lisa A. Brenner & Maryam Tahmasbi Sohi. (2021) Suicide among veterans with amyotrophic lateral sclerosis. Muscle & Nerve 63:6, pages 807-811.
Crossref
Sudarshan Ragunathan, Laura C. Bell, Natenael Semmineh, Ashley M. Stokes, Jeremy M. Shefner, Robert Bowser, Shafeeq Ladha & C. Chad Quarles. (2021) Evaluation of Amyotrophic Lateral Sclerosis-Induced Muscle Degeneration Using Magnetic Resonance-Based Relaxivity Contrast Imaging (RCI). Tomography 7:2, pages 169-179.
Crossref
Ileana M. Howard & Kathleen Burgess. (2021) Telehealth for Amyotrophic Lateral Sclerosis and Multiple Sclerosis. Physical Medicine and Rehabilitation Clinics of North America 32:2, pages 239-251.
Crossref
Marie Dreger, Robert Steinbach, Nayana Gaur, Klara Metzner, Beatrice Stubendorff, Otto W. Witte & Julian Grosskreutz. (2021) Cerebrospinal Fluid Neurofilament Light Chain (NfL) Predicts Disease Aggressiveness in Amyotrophic Lateral Sclerosis: An Application of the D50 Disease Progression Model. Frontiers in Neuroscience 15.
Crossref
Philippe-Pierre Robichaud, Michael Arseneault, Colleen O’Connell, Rodney J. Ouellette & Pier Jr Morin. (2021) Circulating cell-free DNA as potential diagnostic tools for amyotrophic lateral sclerosis. Neuroscience Letters 750, pages 135813.
Crossref
Jang Woo Lee, Seong-Woong Kang & Won Ah Choi. (2021) Clinical Course of Amyotrophic Lateral Sclerosis according to Initial Symptoms: An Analysis of 500 Cases. Yonsei Medical Journal 62:4, pages 338.
Crossref
Ahmed Osama Elmehrath, Yousef Tarek Sonbol & Moaz Yahia Farghal. 2021. Role of Exosomes in Biological Communication Systems. Role of Exosomes in Biological Communication Systems 183 206 .
Marina Martínez-Molina, Herminia Argente-Escrig, Margarita F. Polo, David Hervás, Marina Frasquet, Victoria Cortés, Teresa Sevilla & Juan F. Vázquez-Costa. (2020) Early Referral to an ALS Center Reduces Several Months the Diagnostic Delay: A Multicenter-Based Study. Frontiers in Neurology 11.
Crossref
Danielle Richards, John A. Morren & Erik P. Pioro. (2020) Time to diagnosis and factors affecting diagnostic delay in amyotrophic lateral sclerosis. Journal of the Neurological Sciences 417, pages 117054.
Crossref
Donatienne Van Weehaeghe, Martijn Devrome, Georg Schramm, Joke De Vocht, Wies Deckers, Kristof Baete, Philip Van Damme, Michel Koole & Koen Van Laere. (2020) Combined brain and spinal FDG PET allows differentiation between ALS and ALS mimics. European Journal of Nuclear Medicine and Molecular Imaging 47:11, pages 2681-2690.
Crossref
Young Gi Min, Seok-Jin Choi, Yoon-Ho Hong, Sung-Min Kim, Je-Young Shin & Jung-Joon Sung. (2020) Dissociated leg muscle atrophy in amyotrophic lateral sclerosis/motor neuron disease: the ‘split-leg’ sign. Scientific Reports 10:1.
Crossref
Vincent Grollemund, Gaétan Le Chat, Marie-Sonia Secchi-Buhour, François Delbot, Jean-François Pradat-Peyre, Peter Bede & Pierre-François Pradat. (2020) Development and validation of a 1-year survival prognosis estimation model for Amyotrophic Lateral Sclerosis using manifold learning algorithm UMAP. Scientific Reports 10:1.
Crossref
Michael S. Bereman, Kaylie I. Kirkwood, Tharani Sabaretnam, Sarah Furlong, Dominic B. Rowe, Gilles J. Guillemin, Allyson L. Mellinger & David C. Muddiman. (2020) Metabolite Profiling Reveals Predictive Biomarkers and the Absence of β-Methyl Amino- l -alanine in Plasma from Individuals Diagnosed with Amyotrophic Lateral Sclerosis . Journal of Proteome Research 19:8, pages 3276-3285.
Crossref
Bartłomiej Baumert, Anna Sobuś, Monika Gołąb-Janowska, Edyta Paczkowska, Karolina Łuczkowska, Dorota Rogińska, Alicja Zawiślak, Sławomir Milczarek, Bogumiła Osękowska, Wioletta Pawlukowska, Agnieszka Meller, Karolina Machowska-Sempruch, Agnieszka Wełnicka, Krzysztof Safranow, Przemysław Nowacki & Bogusław Machaliński. (2020) Repeated Application of Autologous Bone Marrow-Derived Lineage-Negative Stem/Progenitor Cells—Focus on Immunological Pathways in Patients with ALS. Cells 9:8, pages 1822.
Crossref
Arina Tamborska, James Bashford, Aidan Wickham, Raquel Iniesta, Urooba Masood, Cristina Cabassi, Domen Planinc, Emma Hodson-Tole, Emmanuel Drakakis, Martyn Boutelle, Kerry Mills & Chris Shaw. (2020) Non-invasive measurement of fasciculation frequency demonstrates diagnostic accuracy in amyotrophic lateral sclerosis. Brain Communications 2:2.
Crossref
Martin Matharan, Stéphane Mathis, Sarah Bonabaud, Louis Carla, Antoine Soulages & Gwendal Le Masson. (2020) Minimizing the Diagnostic Delay in Amyotrophic Lateral Sclerosis: The Role of Nonneurologist Practitioners. Neurology Research International 2020, pages 1-8.
Crossref
Shahar Shelly, John R Mills, Jennifer M Martinez-Thompson, Matt M Rofforth, Sean J Pittock, Jay Mandrekar, James Douglas Triplett, Michelle Mauermann, Divyanshu Dubey & C J Klein. (2020) IgM-gammopathy strongly favours immune treatable MMN and MADSAM over ALS. Journal of Neurology, Neurosurgery & Psychiatry 91:3, pages 324-326.
Crossref
Walter H. MoosDouglas V. FallerIoannis P. GlavasDavid N. HarppIphigenia KanaraAnastasios N. MavrakisJulie PernokasMark PernokasCarl A. PinkertWhitney R. PowersKonstantina SampaniKosta SteliouDemetrios G. VavvasRobert J. ZamboniKrishna KodukulaXiaohong Chen. (2020) Klotho Pathways, Myelination Disorders, Neurodegenerative Diseases, and Epigenetic Drugs. BioResearch Open Access 9:1, pages 94-105.
Crossref
Haley Yost, Riya Patel, Anders Kipp & Tanea T. Reed. 2005. Bailey's Industrial Oil and Fat Products. Bailey's Industrial Oil and Fat Products 1 29 .
Bartłomiej Baumert, Anna Sobuś, Monika Gołąb-Janowska, Zofia Ulańczyk, Edyta Paczkowska, Karolina Łuczkowska, Alicja Zawiślak, Sławomir Milczarek, Bogumiła Osękowska, Agnieszka Meller, Karolina Machowska-Sempruch, Agnieszka Wełnicka, Krzysztof Safranow, Przemysław Nowacki & Bogusław Machaliński. (2020) Local and Systemic Humoral Response to Autologous Lineage-Negative Cells Intrathecal Administration in ALS Patients. International Journal of Molecular Sciences 21:3, pages 1070.
Crossref
Tereza Filipi, Zuzana Hermanova, Jana Tureckova, Ondrej Vanatko & Miroslava Anderova. (2020) Glial Cells—The Strategic Targets in Amyotrophic Lateral Sclerosis Treatment. Journal of Clinical Medicine 9:1, pages 261.
Crossref
William R. Swindell, Colin P. S. Kruse, Edward O. List, Darlene E. Berryman & John J. Kopchick. (2019) ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia. Journal of Translational Medicine 17:1.
Crossref
Ana Dolinar, Blaž Koritnik, Damjan Glavač & Metka Ravnik-Glavač. (2019) Circular RNAs as Potential Blood Biomarkers in Amyotrophic Lateral Sclerosis. Molecular Neurobiology 56:12, pages 8052-8062.
Crossref
Jeremy Roy, Daniel Saucier, Colleen O'Connell & Pier Jr Morin. (2019) Extracellular vesicles and their diagnostic potential in amyotrophic lateral sclerosis. Clinica Chimica Acta 497, pages 27-34.
Crossref
Nana Tian, Liyun Zhang, Zunbo Li, Jianjun Liu, Guohua Lei & Yanyan Ma. (2019) Big data of clinical manifestations combined with neuroelectrophysiologic features in the early diagnosis of motor neuron disease. Journal of Ambient Intelligence and Humanized Computing 10:10, pages 3879-3888.
Crossref
Ella Zeldich, Ci-Di Chen, Emma Boden, Bryce Howat, Jason S. Nasse, Dean Zeldich, Anthony G. Lambert, Andrea Yuste, Jonathan D. Cherry, Rebecca M. Mathias, Qicheng Ma, Nelson C. Lau, Ann C. McKee, Theo Hatzipetros & Carmela R. Abraham. (2019) Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS. Journal of Molecular Neuroscience 69:2, pages 264-285.
Crossref
Lisa D. Hobson‐Webb & Zachary Simmons. (2019) ULTRASOUND IN THE DIAGNOSIS AND MONITORING OF AMYOTROPHIC LATERAL SCLEROSIS: A REVIEW. Muscle & Nerve 60:2, pages 114-123.
Crossref
Ryuji Kaji, Takashi Imai, Yasuo Iwasaki, Koichi Okamoto, Masanori Nakagawa, Yasuo Ohashi, Takao Takase, Takahisa Hanada, Hiroki Shimizu, Kunio Tashiro & Shigeki Kuzuhara. (2019) Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study. Journal of Neurology, Neurosurgery & Psychiatry 90:4, pages 451-457.
Crossref
Daniel Saucier, Gabriel Wajnberg, Jeremy Roy, Annie-Pier Beauregard, Simi Chacko, Nicolas Crapoulet, Sébastien Fournier, Anirban Ghosh, Stephen M. Lewis, Alier Marrero, Colleen O'Connell, Rodney J. Ouellette & Pier Jr Morin. (2019) Identification of a circulating miRNA signature in extracellular vesicles collected from amyotrophic lateral sclerosis patients. Brain Research 1708, pages 100-108.
Crossref
Koichi Tsunoda, Mihiro Takazawa, Tonghyo Chong & Yoko Morita. (2019) Slow, slurred speech as an initial complaint in amyotrophic lateral sclerosis. Auris Nasus Larynx 46:2, pages 193-195.
Crossref
Rangariroyashe Hannah Chipika, Eoin Finegan, Stacey Li Hi Shing, Orla Hardiman & Peter Bede. (2019) Tracking a Fast-Moving Disease: Longitudinal Markers, Monitoring, and Clinical Trial Endpoints in ALS. Frontiers in Neurology 10.
Crossref
Roger G. Whittaker, Paola Porcari, Luis Braz, Timothy L. Williams, Ian S. Schofield & Andrew M. Blamire. (2019) Functional magnetic resonance imaging of human motor unit fasciculation in amyotrophic lateral sclerosis. Annals of Neurology 85:3, pages 455-459.
Crossref
Nimeshan GeevasingaJames HowellsParvathi MenonMehdi van den Bos, Kazumoto ShibuyaJosé Manuel MatamalaSusanna B. ParkKaren BythMatthew C. KiernanSteve Vucic. (2019) Amyotrophic lateral sclerosis diagnostic index. Neurology 92:6.
Crossref
Federico Verde, Petra Steinacker, Jochen H Weishaupt, Jan Kassubek, Patrick Oeckl, Steffen Halbgebauer, Hayrettin Tumani, Christine A F von Arnim, Johannes Dorst, Emily Feneberg, Benjamin Mayer, Hans-Peter Müller, Martin Gorges, Angela Rosenbohm, Alexander E Volk, Vincenzo Silani, Albert C Ludolph & Markus Otto. (2019) Neurofilament light chain in serum for the diagnosis of amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery & Psychiatry 90:2, pages 157-164.
Crossref
Koen Poesen & Philip Van Damme. (2019) Diagnostic and Prognostic Performance of Neurofilaments in ALS. Frontiers in Neurology 9.
Crossref
Helder Vieira, Nelson Costa, Tomás Sousa, Sara Reis & Luis Coelho. (2019) Voice-Based Classification of Amyotrophic Lateral Sclerosis: Where Are We and Where Are We Going? A Systematic Review. Neurodegenerative Diseases 19:5-6, pages 163-170.
Crossref
Elmira Agah, Fatemeh Saleh, Hossein Sanjari Moghaddam, Amene Saghazadeh, Abbas Tafakhori & Nima Rezaei. (2018) CSF and blood biomarkers in amyotrophic lateral sclerosis: protocol for a systematic review and meta-analysis. Systematic Reviews 7:1.
Crossref
Montserrat Diaz-AbadJennifer R. BuczynerBrigit R. VenzaSteven M. ScharfJustin Y. KwanBrooke Lubinski & James W. Russell. (2018) Poor Sleep Quality in Patients With Amyotrophic Lateral Sclerosis at the Time of Diagnosis. Journal of Clinical Neuromuscular Disease 20:2, pages 60-68.
Crossref
Ileana M. Howard & Nassim Rad. (2018) Electrodiagnostic Testing for the Diagnosis and Management of Amyotrophic Lateral Sclerosis. Physical Medicine and Rehabilitation Clinics of North America 29:4, pages 669-680.
Crossref
Anne Hogden, Samar M. Aoun & Peter L. Silbert. (2018) Palliative Care in Neurology: Integrating a Palliative Approach to Amyotrophic Lateral Sclerosis Care. EMJ Neurology, pages 68-76.
Crossref
Nassim Rad & Michael D. Weiss. (2018) MicroRNAS: Mapping out the road to amyotrophic lateral sclerosis . Muscle & Nerve 58:2, pages 189-190.
Crossref
Michael Benatar, Joanne Wuu, Peter M. Andersen, Vittoria Lombardi & Andrea Malaspina. (2018) Neurofilament light: A candidate biomarker of presymptomatic amyotrophic lateral sclerosis and phenoconversion. Annals of Neurology 84:1, pages 130-139.
Crossref
Maxim De Schaepdryver, Andreas Jeromin, Benjamin Gille, Kristl G Claeys, Victor Herbst, Britta Brix, Philip Van Damme & Koen Poesen. (2018) Comparison of elevated phosphorylated neurofilament heavy chains in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery & Psychiatry 89:4, pages 367-373.
Crossref
Euna Lee, Fangxu Xing, Sung Ahn, Timothy G. Reese, Ruopeng Wang, Jordan R. Green, Nazem Atassi, Van J. Wedeen, Georges El Fakhri & Jonghye Woo. (2018) Magnetic resonance imaging based anatomical assessment of tongue impairment due to amyotrophic lateral sclerosis: A preliminary study. The Journal of the Acoustical Society of America 143:4, pages EL248-EL254.
Crossref
Raymond Farah, Hayat Haraty, Ziad Salame, Youssef Fares, David M. Ojcius & Najwane Said Sadier. (2018) Salivary biomarkers for the diagnosis and monitoring of neurological diseases. Biomedical Journal 41:2, pages 63-87.
Crossref
Robert J. Stachler, David O. Francis, Seth R. Schwartz, Cecelia C. Damask, German P. Digoy, Helene J. Krouse, Scott J. McCoy, Daniel R. Ouellette, Rita R. Patel, Charles (Charlie) W. Reavis, Libby J. Smith, Marshall Smith, Steven W. Strode, Peak Woo & Lorraine C. Nnacheta. (2018) Clinical Practice Guideline: Hoarseness (Dysphonia) (Update). Otolaryngology–Head and Neck Surgery 158:S1.
Crossref
Said R Beydoun & Jeffrey Rosenfeld. (2018) Edaravone in Amyotrophic Lateral Sclerosis’Lessons from the Clinical Development Program and the Importance of a Strategic Clinical Trial Design. US Neurology 14:1, pages 47.
Crossref
Stephen A. Goutman. (2017) Diagnosis and Clinical Management of Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. CONTINUUM: Lifelong Learning in Neurology 23:5, pages 1332-1359.
Crossref
G. Querin, M. M. El Mendili, T. Lenglet, S. Delphine, V. Marchand‐Pauvert, H. Benali & P.‐F. Pradat. (2017) Spinal cord multi‐parametric magnetic resonance imaging for survival prediction in amyotrophic lateral sclerosis. European Journal of Neurology 24:8, pages 1040-1046.
Crossref
Rui Jia, Stephanie Shepheard, Jiaoting Jin, Fangfang Hu, Xing Zhao, Li Xue, Li Xiang, Huaguang Qi, Qiumin Qu, Feng Guo, Mary-Louise Rogers & Jingxia Dang. (2017) Urinary Extracellular Domain of Neurotrophin Receptor p75 as a Biomarker for Amyotrophic Lateral Sclerosis in a Chinese cohort. Scientific Reports 7:1.
Crossref
James B. Caress. (2017) Optimal muscle selection in amyotrophic lateral sclerosis and the end of the 4-limb EMG. Muscle & Nerve 56:1, pages 4-6.
Crossref
Miriam Galvin, Padhraig Ryan, Sinead Maguire, Mark Heverin, Caoifa Madden, Alice Vajda, Charles Normand & Orla Hardiman. (2017) The path to specialist multidisciplinary care in amyotrophic lateral sclerosis: A population- based study of consultations, interventions and costs. PLOS ONE 12:6, pages e0179796.
Crossref
Angela Rosenbohm, Raphael S. Peter, Siegfried Erhardt, Dorothée Lulé, Dietrich Rothenbacher, Albert C. Ludolph & Gabriele Nagel. (2017) Epidemiology of amyotrophic lateral sclerosis in Southern Germany. Journal of Neurology 264:4, pages 749-757.
Crossref
Nimeshan Geevasinga, Parvathi Menon, P. Hande Özdinler, Matthew C. Kiernan & Steve Vucic. (2016) Pathophysiological and diagnostic implications of cortical dysfunction in ALS. Nature Reviews Neurology 12:11, pages 651-661.
Crossref
Nicole A. Restrepo, Mariusz Butkiewicz, Josephine A. McGrath & Dana C. Crawford. (2016) Shared Genetic Etiology of Autoimmune Diseases in Patients from a Biorepository Linked to De-identified Electronic Health Records. Frontiers in Genetics 7.
Crossref
YongPing Chen, QianQian Wei, XuePing Chen, ChunYu Li, Bei Cao, RuWei Ou, Shinji Hadano & Hui-Fang Shang. (2016) Aberration of miRNAs Expression in Leukocytes from Sporadic Amyotrophic Lateral Sclerosis. Frontiers in Molecular Neuroscience 9.
Crossref
Conceicao Moura Mirian, Rita Carvalho Garbi Novaes Maria, SSP Zago Yuri, Junio Eduardo Emanoel & Augusto Casulari Luiz. (2016) Efficacy and effectiveness of drug treatments in amyotrophic lateral sclerosis: A systematic review with meta-analysis. African Journal of Pharmacy and Pharmacology 10:13, pages 257-269.
Crossref
B. Marin, E. Beghi, C. Vial, E. Bernard, G. Lautrette, P. Clavelou, N. Guy, G. Lemasson, S. Debruxelles, P. Cintas, J. C. Antoine, J. P. Camdessanche, G. Logroscino, P. M. Preux & P. Couratier. (2016) Evaluation of the application of the European guidelines for the diagnosis and clinical care of amyotrophic lateral sclerosis ( ALS ) patients in six French ALS centres . European Journal of Neurology 23:4, pages 787-795.
Crossref
Gali Zimmerman-Moreno, Dafna Ben Bashat, Moran Artzi, Beatrice Nefussy, Vivian Drory, Orna Aizenstein & Hayit Greenspan. (2016) Whole brain fiber-based comparison (FBC)-A tool for diffusion tensor imaging-based cohort studies. Human Brain Mapping 37:2, pages 477-490.
Crossref
E.O. Talbott, A.M. Malek & D. Lacomis. 2016. Neuroepidemiology. Neuroepidemiology 225 238 .
Elena Ratti & James D. Berry. 2016. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry 685 712 .
Angelina Cistaro. 2016. PET-CT and PET-MRI in Neurology. PET-CT and PET-MRI in Neurology 231 246 .
Ji He, Marie Mangelsdorf, Dongsheng Fan, Perry Bartlett & Matthew A. Brown. (2014) Amyotrophic Lateral Sclerosis Genetic Studies. The Neuroscientist 21:6, pages 599-615.
Crossref
Sabrina Paganoni, Chafic Karam, Nanette Joyce, Richard Bedlack & Gregory T. Carter. (2015) Comprehensive rehabilitative care across the spectrum of amyotrophic lateral sclerosis. NeuroRehabilitation 37:1, pages 53-68.
Crossref
Alan B. Sanderson, John C. Novak, Steven M. Nash, Stephen J. Kolb & John T. Kissel. (2015) Laboratory evaluation of suspected motor neuron disease: A survey of physicians. Muscle & Nerve 52:1, pages 83-87.
Crossref
Frank Cloutier, Alier Marrero, Colleen O’Connell & Pier Jr Morin. (2014) MicroRNAs as Potential Circulating Biomarkers for Amyotrophic Lateral Sclerosis. Journal of Molecular Neuroscience 56:1, pages 102-112.
Crossref
Esther Verstraete & Bradley R. Foerster. (2015) Neuroimaging as a New Diagnostic Modality in Amyotrophic Lateral Sclerosis. Neurotherapeutics 12:2, pages 403-416.
Crossref
Katharine A. Nicholson, Merit E. Cudkowicz & James D. Berry. (2015) Clinical Trial Designs in Amyotrophic Lateral Sclerosis: Does One Design Fit All?. Neurotherapeutics 12:2, pages 376-383.
Crossref
Stephen A. Goutman, Kevin S. Chen & Eva L. Feldman. (2015) Recent Advances and the Future of Stem Cell Therapies in Amyotrophic Lateral Sclerosis. Neurotherapeutics 12:2, pages 428-448.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.