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Dialogues in Clinical Neuroscience Volume 19, 2017 - Issue 3
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Basic Research

Animal models of addiction

Modelos animales de adicciones

Modèles animaux d'addiction

Rainer SpanagelInstitute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, GermanyCorrespondence[email protected]
Pages 247-258 | Published online: 01 Apr 2022

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Jana Ruda-Kucerova, Petra Amchova, Filip Siska & Yousef Tizabi. (2021) NBQX attenuates relapse of nicotine seeking but not nicotine and methamphetamine self-administration in rats. The World Journal of Biological Psychiatry 22:10, pages 733-743.
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Rainer Spanagel. (2020) Cannabinoids and the endocannabinoid system in reward processing and addiction: from mechanisms to interventions
. Dialogues in Clinical Neuroscience 22:3, pages 241-250.
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Fiona Kehinde, Opeoluwa Oduyeye & Raihan Mohammed. (2019) Could the link between drug addiction in adulthood and substance use in adolescence result from a blurring of the boundaries between incentive and hedonic processes?. Substance Abuse and Rehabilitation 10, pages 33-46.
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Tatiana Wscieklica, Luciana Le Sueur-Maluf, Leandro Prearo, Rafael Conte, Milena de Barros Viana & Isabel Cristina Céspedes. (2019) Chronic intermittent ethanol administration differentially alters DeltaFosB immunoreactivity in cortical-limbic structures of rats with high and low alcohol preference. The American Journal of Drug and Alcohol Abuse 45:3, pages 264-275.
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Megan R. Greener & Sarah J. Storr. (2023) Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling. Frontiers in Molecular Neuroscience 16.
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Pearl N. Cummins-Beebee, Maggie M. Chvilicek & Adrian Rothenfluh. (2023) The Stage-Based Model of Addiction—Using Drosophila to Investigate Alcohol and Psychostimulant Responses. International Journal of Molecular Sciences 24:13, pages 10909.
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Allyson L. Spence, Courtney M. Keller, Maggie Mott & Kevin S. Murnane. 2023. Substance Use and Addiction Research. Substance Use and Addiction Research 11 22 .
Allyson L. Spence, Ndeloh Fontem & Christine Feltman. 2023. Substance Use and Addiction Research. Substance Use and Addiction Research 3 9 .
Mona A. Raslan. (2022) Natural Products for the Treatment of Drug Addiction: Narrative Review. Chemistry & Biodiversity 19:12.
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Garikoitz Azkona & Rosario Sanchez-Pernaute. (2022) Mice in translational neuroscience: What R we doing?. Progress in Neurobiology 217, pages 102330.
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Oscar V. Torres. (2022) Sex Differences in Psychostimulant Abuse: Implications for Estrogen Receptors and Histone Deacetylases. Genes 13:5, pages 892.
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Crossref
A. Ilari, L. Curti, M. Petrella, N. Cannella, A. La Rocca, G. Ranieri, E. Gerace, D. Iezzi, L. Silvestri, G. Mannaioni, R. Ciccocioppo & A. Masi. (2022) Moderate ethanol drinking is sufficient to alter Ventral Tegmental Area dopamine neurons activity via functional and structural remodeling of GABAergic transmission. Neuropharmacology 203, pages 108883.
Crossref
Kathryn A. Coniglio, Marita Cooper & Edward A. Selby. (2021) Behavioral reinforcement of pathological exercise in anorexia nervosa. International Journal of Eating Disorders 55:2, pages 184-192.
Crossref
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Crossref
Monica Mazzelli. 2022. Encyclopedia of Behavioral Neuroscience, 2nd edition. Encyclopedia of Behavioral Neuroscience, 2nd edition 688 694 .
Elisa Mombelli. 2022. Encyclopedia of Behavioral Neuroscience, 2nd edition. Encyclopedia of Behavioral Neuroscience, 2nd edition 674 681 .
Christine Lalonde & Steven Arnocky. 2022. Encyclopedia of Animal Cognition and Behavior. Encyclopedia of Animal Cognition and Behavior 737 742 .
Florence Allain, Ndeye Aissatou Ndiaye & Anne-Noël Samaha. 2022. Methods for Preclinical Research in Addiction. Methods for Preclinical Research in Addiction 151 172 .
Claire Leroy & Wadad Saba. (2021) Contribution of TSPO imaging in the understanding of the state of gliosis in substance use disorders. European Journal of Nuclear Medicine and Molecular Imaging 49:1, pages 186-200.
Crossref
Marcus W. Meinhardt, Simone PfarrGrégory Fouquet, Cathrin Rohleder, Manuela L. MeinhardtJanet Barroso-Flores, Rebecca HoffmannJérôme Jeanblanc, Elisabeth Paul, Konstantin Wagner, Anita C. HanssonGeorg Köhr, Nils MeierOliver von Bohlen und Halbach, Richard L. Bell, Heike EndepolsBernd Neumaier, Kai Schönig, Dusan Bartsch, Mickaël Naassila, Rainer Spanagel & Wolfgang H. Sommer. (2021) Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism. Science Advances 7:47.
Crossref
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Crossref
Joel Gelernter & Renato Polimanti. (2021) Genetics of substance use disorders in the era of big data. Nature Reviews Genetics 22:11, pages 712-729.
Crossref
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Crossref
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Crossref
Steven J. Nieto, Erica N. Grodin, Claudia G. Aguirre, Alicia Izquierdo & Lara A. Ray. (2021) Translational opportunities in animal and human models to study alcohol use disorder. Translational Psychiatry 11:1.
Crossref
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Crossref
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Crossref
Lucja Kudla & Ryszard Przewlocki. (2021) Influence of G protein-biased agonists of μ-opioid receptor on addiction-related behaviors. Pharmacological Reports 73:4, pages 1033-1051.
Crossref
Darlene Mae Ortiz, Raly James Perez Custodio, Arvie Abiero, Chrislean Jun Botanas, Leandro Val Sayson, Mikyung Kim, Hyun Jun Lee, Hee Jin Kim, Youngdo Jeong, Sulmin Yoon, Yong Sup Lee & Jae Hoon Cheong. (2020) The dopaminergic alterations induced by 4‐F‐PCP and 4‐Keto‐PCP may enhance their drug‐induced rewarding and reinforcing effects: Implications for abuse. Addiction Biology 26:4.
Crossref
Mi Young Lee, Bong Hyo Lee, Hee Young Kim & Chae Ha Yang. (2021) Bidirectional role of acupuncture in the treatment of drug addiction. Neuroscience & Biobehavioral Reviews 126, pages 382-397.
Crossref
Arnavi Patel. (2021) Animal Models of Psychiatric Disorders: A Literature Review. Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal 5:6, pages 1-7.
Crossref
Ayan Ahmed, Manuel J. Ruiz, Kathrin Cohen Kadosh, Robert Patton & Davinia M. Resurrección. (2021) Khat and neurobehavioral functions: A systematic review. PLOS ONE 16:6, pages e0252900.
Crossref
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Crossref
Andrea KingAshley VenaDeborah S. HasinHarriet deWitSean J. O’ConnorDingcai Cao. (2021) Subjective Responses to Alcohol in the Development and Maintenance of Alcohol Use Disorder. American Journal of Psychiatry 178:6, pages 560-571.
Crossref
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Crossref
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Crossref
Mickael Degoulet, Alix Tiran-Cappello, Etienne Combrisson, Christelle Baunez & Yann Pelloux. (2021) Subthalamic low-frequency oscillations predict vulnerability to cocaine addiction. Proceedings of the National Academy of Sciences 118:14.
Crossref
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Crossref
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Crossref
Anna K. Radke, Elizabeth A. Sneddon & Sean C. Monroe. (2021) Studying Sex Differences in Rodent Models of Addictive Behavior. Current Protocols 1:4.
Crossref
L Blazquez-Llorca, M Miguéns, M Montero-Crespo, A Selvas, J Gonzalez-Soriano, E Ambrosio & J DeFelipe. (2021) 3D Synaptic Organization of the Rat CA1 and Alterations Induced by Cocaine Self-Administration. Cerebral Cortex 31:4, pages 1927-1952.
Crossref
Anna Maria Borruto, Serena Stopponi, Hongwu Li, Friedbert Weiss, Marisa Roberto & Roberto Ciccocioppo. (2021) Genetically selected alcohol-preferring msP rats to study alcohol use disorder: Anything lost in translation?. Neuropharmacology 186, pages 108446.
Crossref
Kathryn D. Fischer, Lori A. Knackstedt & Paul A. Rosenberg. (2021) Glutamate homeostasis and dopamine signaling: Implications for psychostimulant addiction behavior. Neurochemistry International 144, pages 104896.
Crossref
Cédric Bertrand, Chloé Deschamps, Kevin Rabiant, Stéphane Peineau, Johann Antol, Margaret Martinetti, Mickael Naassila, Catherine Vilpoux & Olivier Pierrefiche. (2021) Patch‐Clamp Recording of Low Frequency Stimulation‐induced Long‐Term Synaptic Depression in Rat Hippocampus Slices During Early and Late Neurodevelopment. Alcoholism: Clinical and Experimental Research 45:2, pages 351-364.
Crossref
María José Cano‐Cebrián, Sandra Fernández‐Rodríguez, Lucia Hipólito, Luis Granero, Ana Polache & Teodoro Zornoza. (2020) Efficacy of N‐acetylcysteine in the prevention of alcohol relapse‐like drinking: Study in long‐term ethanol‐experienced male rats. Journal of Neuroscience Research 99:2, pages 638-648.
Crossref
Pawel Grochecki, Irena Smaga, Malgorzata Lopatynska-Mazurek, Ewa Gibula-Tarlowska, Ewa Kedzierska, Joanna Listos, Sylwia Talarek, Marta Marszalek-Grabska, Magdalena Hubalewska-Mazgaj, Agnieszka Korga-Plewko, Jaroslaw Dudka, Zbigniew Marzec, Małgorzata Filip & Jolanta H. Kotlinska. (2021) Effects of Mephedrone and Amphetamine Exposure during Adolescence on Spatial Memory in Adulthood: Behavioral and Neurochemical Analysis. International Journal of Molecular Sciences 22:2, pages 589.
Crossref
Yedy Israel, María Elena Quintanilla, Fernando Ezquer, Paola Morales, Daniela Santapau, Pablo Berríos‐Cárcamo, Marcelo Ezquer, Belen Olivares & Mario Herrera‐Marschitz. (2019) Aspirin and N‐acetylcysteine co‐administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation‐oxidative stress self‐perpetuation. Addiction Biology 26:1.
Crossref
Carlos Ibañez, Sergio Vicencio, María Elena Quintanilla & Pedro Maldonado. (2019) Interoception and alcohol addiction: Vagotomy induces long‐lasting suppression of relapse‐type behavior. Addiction Biology 26:1.
Crossref
Yannick Fotio, Anna Maria Borruto, Federica Benvenuti, Gregory Demopulos, George Gaitanaris, Marisa Roberto & Roberto Ciccocioppo. (2020) Activation of peroxisome proliferator-activated receptor γ reduces alcohol drinking and seeking by modulating multiple mesocorticolimbic regions in rats. Neuropsychopharmacology 46:2, pages 360-367.
Crossref
Patrick R. Melugin, Suzanne O. Nolan & Cody A. Siciliano. 2021. Neurobiology of Addiction and Co-Morbid Disorders. Neurobiology of Addiction and Co-Morbid Disorders 371 407 .
Benjamin E. Blass. 2021. Basic Principles of Drug Discovery and Development. Basic Principles of Drug Discovery and Development 371 420 .
Christine Lalonde & Steven Arnocky. 2020. Encyclopedia of Animal Cognition and Behavior. Encyclopedia of Animal Cognition and Behavior 1 6 .
Drielle Feitosa Silva & André Amaral Bravin. 2021. Drugs and Human Behavior. Drugs and Human Behavior 219 230 .
Florence Allain & Anne-Noël Samaha. 2021. The Brain Reward System. The Brain Reward System 209 232 .
Marcos Ucha, David Roura-Martínez, Emilio Ambrosio & Alejandro Higuera-Matas. (2020) The role of the mTOR pathway in models of drug-induced reward and the behavioural constituents of addiction. Journal of Psychopharmacology 34:11, pages 1176-1199.
Crossref
Raly James Perez Custodio, Leandro Val Sayson, Chrislean Jun Botanas, Arvie Abiero, Kyung Yi You, Mikyung Kim, Hyun Jun Lee, Sung Yeun Yoo, Kun Won Lee, Yong Sup Lee, Joung‐Wook Seo, In Soo Ryu, Hee Jin Kim & Jae Hoon Cheong. (2019) 25B‐NBOMe, a novel N ‐2‐methoxybenzyl‐phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: Evidence of abuse potential . Addiction Biology 25:6.
Crossref
Andrew R. Craig, William E. Sullivan, Kate Derrenbacker, Arohan Rimal, Nicole M. DeRosa & Henry S. Roane. (2020) An evaluation of resurgence in mice. Learning and Motivation 72, pages 101671.
Crossref
Romain Icick, Benoît Forget, Isabelle Cloëz-Tayarani, Stéphanie Pons, Uwe Maskos & Morgane Besson. (2020) Genetic susceptibility to nicotine addiction: Advances and shortcomings in our understanding of the CHRNA5/A3/B4 gene cluster contribution. Neuropharmacology 177, pages 108234.
Crossref
Maria E. Burkovetskaya, Qiaoling Liu, Anish K. Vadukoot, Nagsen Gautam, Yazen Alnouti, Sushil Kumar, Klaus Miczek, Shilpa Buch, Corey R. Hopkins & Minglei Guo. (2020) KVA-D-88, a Novel Preferable Phosphodiesterase 4B Inhibitor, Decreases Cocaine-Mediated Reward Properties in Vivo . ACS Chemical Neuroscience 11:15, pages 2231-2242.
Crossref
Marjorie C. Gondré-Lewis, Rosemary Bassey & Kenneth Blum. (2020) Pre-clinical models of reward deficiency syndrome: A behavioral octopus. Neuroscience & Biobehavioral Reviews 115, pages 164-188.
Crossref
Marcus W. Meinhardt, Cansu Güngör, Ivan Skorodumov, Lea J. Mertens & Rainer Spanagel. (2020) Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse. Neuropsychopharmacology 45:8, pages 1316-1322.
Crossref
Jannike M. Andersen, Siri H. Opdal, Christian P. Müller & Fernando Boix. (2020) CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment. Behavioural Brain Research 390, pages 112676.
Crossref
Carolina L. Haass‐Koffler. (2020) Protein Tyrosine Phosphatase β/ζ and Alcohol Use Disorder: A Commentary. Alcoholism: Clinical and Experimental Research 44:6, pages 1189-1191.
Crossref
Michel Engeln, Swarup Mitra, Ramesh Chandra, Utsav Gyawali, Megan E. Fox, David M. Dietz & Mary Kay Lobo. (2020) Sex-Specific Role for Egr3 in Nucleus Accumbens D2-Medium Spiny Neurons Following Long-Term Abstinence From Cocaine Self-administration. Biological Psychiatry 87:11, pages 992-1000.
Crossref
Dorrit Inbar, Shani Gendelis, Shanee Mesner, Shira Menahem & Yonatan M. Kupchik. (2019) Chronic calorie‐dense diet drives differences in motivated food seeking between obesity‐prone and resistant mice. Addiction Biology 25:3.
Crossref
Giulia Zanni, Matthew J. DeSalle, Hannah M. Deutsch, Gordon A. Barr & Amelia J. Eisch. (2020) Female and male rats readily consume and prefer oxycodone to water in a chronic, continuous access, two-bottle oral voluntary paradigm. Neuropharmacology 167, pages 107978.
Crossref
Lee Hogarth. (2020) Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory. Neuropsychopharmacology 45:5, pages 720-735.
Crossref
Udita Datta, Sarah E. Schoenrock, Jason A. Bubier, Molly A. Bogue, James D. Jentsch, Ryan W. Logan, Lisa M. Tarantino & Elissa J. Chesler. (2020) Prospects for finding the mechanisms of sex differences in addiction with human and model organism genetic analysis. Genes, Brain and Behavior 19:3.
Crossref
Andreas Heinz, Falk Kiefer, Michael N. Smolka, Tanja Endrass, Christian Beste, Anne Beck, Shuyan Liu, Alexander Genauck, Lydia Romund, Tobias Banaschewski, Felix Bermpohl, Lorenz Deserno, Raymond J. Dolan, Daniel Durstewitz, Ulrich Ebner‐Priemer, Herta Flor, Anita C. Hansson, Christine Heim, Derik Hermann, Stefan Kiebel, Peter Kirsch, Clemens Kirschbaum, Georgia Koppe, Michael Marxen, Andreas Meyer‐Lindenberg, Wolfgang E. Nagel, Hamid R. Noori, Maximilian Pilhatsch, Josef Priller, Marcella Rietschel, Nina Romanczuk‐Seiferth, Florian Schlagenhauf, Wolfgang H. Sommer, Jan Stallkamp, Andreas Ströhle, Ann‐Kathrin Stock, Georg Winterer, Christine Winter, Henrik Walter, Stephanie Witt, Sabine Vollstädt‐Klein, Michael A. Rapp, Heike Tost & Rainer Spanagel. (2019) Addiction Research Consortium: Losing and regaining control over drug intake (ReCoDe)—From trajectories to mechanisms and interventions. Addiction Biology 25:2.
Crossref
Shahram Zarrabian, Esmail Riahi, Sara Karimi, Yasaman Razavi & Abbas Haghparast. (2020) The potential role of the orexin reward system in future treatments for opioid drug abuse. Brain Research 1731, pages 146028.
Crossref
Elke Humer, Thomas Probst & Christoph Pieh. (2020) Metabolomics in Psychiatric Disorders: What We Learn from Animal Models. Metabolites 10:2, pages 72.
Crossref
Wendy Umberger & Lynn Gaddis. (2020) The Science of Addiction Through the Lens of Opioid Treatment for Chronic Noncancer Pain. Pain Management Nursing 21:1, pages 57-64.
Crossref
Kaj Fried & Per T Hansson. (2020) Animal models of trigeminal neuralgia: A commentary. Molecular Pain 16, pages 174480692098053.
Crossref
Matt Field & Inge Kersbergen. (2019) Are animal models of addiction useful?. Addiction 115:1, pages 6-12.
Crossref
Kari A. Johnson & David M. Lovinger. 2020. From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors. From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors 193 232 .
Kathryn A. Cunningham, Leonard L. Howell & Noelle C. Anastasio. 2020. Handbook of the Behavioral Neurobiology of Serotonin. Handbook of the Behavioral Neurobiology of Serotonin 745 802 .
Brittany N. Kuhn, Peter W. Kalivas & Ana-Clara Bobadilla. (2019) Understanding Addiction Using Animal Models. Frontiers in Behavioral Neuroscience 13.
Crossref
Shane O’Mahony. (2019) From Shebeen’s to supervised injecting centres: The socio-historical construction and portrayal of addiction in modern Ireland. Irish Journal of Sociology 27:2, pages 153-197.
Crossref
Tatiane T. Takahashi, Valentina Vengeliene, Thomas Enkel, Sara Reithofer & Rainer Spanagel. (2019) Pavlovian to Instrumental Transfer Responses Do Not Correlate With Addiction-Like Behavior in Rats. Frontiers in Behavioral Neuroscience 13.
Crossref
Jerome Clifford Foo, Valentina Vengeliene, Hamid Reza Noori, Ikuhiro Yamaguchi, Kenji Morita, Toru Nakamura, Yoshiharu Yamamoto & Rainer Spanagel. (2019) Drinking Levels and Profiles of Alcohol Addicted Rats Predict Response to Nalmefene. Frontiers in Pharmacology 10.
Crossref
Riccardo Avvisati, Inger Lise Bogen, Jannike M. Andersen, Vigdis Vindenes, Jørg Mørland, Aldo Badiani & Fernando Boix. (2019) The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat. Neuropharmacology 150, pages 192-199.
Crossref
Kurt Rasmussen, David A. White & Jane B. Acri. (2018) NIDA’s medication development priorities in response to the Opioid Crisis: ten most wanted. Neuropsychopharmacology 44:4, pages 657-659.
Crossref
Lisa R. Gerak, David R. Maguire & Charles P. France. 2020. Substance Use Disorders. Substance Use Disorders 127 145 .
Jun-Tao Gao, Chloe J. Jordan, Guo-Hua Bi, Yi He, Hong-Ju Yang, Eliot L. Gardner & Zheng-Xiong Xi. (2018) Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats. Neuropsychopharmacology 43:13, pages 2615-2626.
Crossref
Elisa Rodríguez-Ortega & Inmaculada Cubero. (2018) Environmental Enrichment Modulates Drug Addiction and Binge-Like Consumption of Highly Rewarding Substances: A Role for Anxiety and Compulsivity Brain Systems?. Frontiers in Behavioral Neuroscience 12.
Crossref
M. Naassila. (2018) Alcoologie : que peuvent attendre les cliniciens des neurobiologistes ? Que peuvent attendre les neurobiologistes des cliniciens en 2018 ?. French Journal of Psychiatry 1, pages S4.
Crossref
Valentina Vengeliene, Tatiane T. Takahashi, Olga A. Dravolina, Irina Belozertseva, Edwin Zvartau, Anton Y. Bespalov & Rainer Spanagel. (2018) Efficacy and side effects of baclofen and the novel GABAB receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction. Psychopharmacology 235:7, pages 1955-1965.
Crossref
Rainer Spanagel. (2018) Aberrant choice behavior in alcoholism. Science 360:6395, pages 1298-1299.
Crossref

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