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Clinical Features

Impact of Sodium Glucose Cotransporter 2 Inhibitors on Weight in Patients With Type 2 Diabetes Mellitus

, MD
Pages 92-100 | Published online: 13 Mar 2015

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Read on this site (5)

Kohei Kaku, Kazuhiro Yamamoto, Yumiko Fukushima, Seiko Mizuno & Daisuke Nitta. (2022) Safety and effectiveness of empagliflozin according to body mass index in Japanese patients with type 2 diabetes: a subgroup analysis of a 3-year post-marketing surveillance study. Expert Opinion on Drug Safety 21:11, pages 1411-1422.
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Konstantinos P. Imprialos, Konstantinos Stavropoulos, Michael Doumas, Asterios Karagiannis & Vasilios G. Athyros. (2017) The effect of SGLT2 inhibitors on cardiovascular events and renal function. Expert Review of Clinical Pharmacology 10:11, pages 1251-1261.
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André J. Scheen. (2015) SGLT2 inhibition: efficacy and safety in type 2 diabetes treatment. Expert Opinion on Drug Safety 14:12, pages 1879-1904.
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André J Scheen. (2014) Evaluating SGLT2 inhibitors for type 2 diabetes: pharmacokinetic and toxicological considerations. Expert Opinion on Drug Metabolism & Toxicology 10:5, pages 647-663.
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Articles from other publishers (26)

T. S. Panevin, M. S. Eliseev, A. O. Bobkova, A. E. Dimitreva & M. M. Urumova. (2023) The use of dapaglifl ozin in a comorbid patient: new perspectives. Nephrology (Saint-Petersburg) 27:2, pages 109-115.
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Youn Huh & Young Sik Kim. (2022) Predictors for successful weight reduction during treatment with Dapagliflozin among patients with type 2 diabetes mellitus in primary care. BMC Primary Care 23:1.
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T. S. Panevin, M. S. Eliseev, M. V. Shestakova & E. L. Nasonov. (2020) Advantages of therapy with sodium glucose cotransporter type 2 inhibitors in patients with type 2 diabetes mellitus in combination with hyperuricemia and gout. Terapevticheskii arkhiv 92:5, pages 110-118.
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Konstantinos Imprialos, Konstantinos Stavropoulos & Vasilios Papademetriou. (2019) Sodium-Glucose Cotransporter-2 Inhibitors, Reverse J-Curve Pattern, and Mortality in Heart Failure. Heart Failure Clinics 15:4, pages 519-530.
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Ze Chen & Gerui Li. (2019) Sodium-Glucose Co-Transporter 2 Inhibitors Compared with Sulfonylureas in Patients with Type 2 Diabetes Inadequately Controlled on Metformin: A Meta-Analysis of Randomized Controlled Trials. Clinical Drug Investigation 39:6, pages 521-531.
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Francisco J. Tinahones, Baptist Gallwitz, Matias Nordaby, Sophia Götz, Mario Maldonado-Lutomirsky, Hans J. Woerle & Uli C. Broedl. (2017) Linagliptin as add-on to empagliflozin and metformin in patients with type 2 diabetes: Two 24-week randomized, double-blind, double-dummy, parallel-group trials. Diabetes, Obesity and Metabolism 19:2, pages 266-274.
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Samy Hadjadj, Julio Rosenstock, Thomas Meinicke, Hans J. Woerle & Uli C. Broedl. (2016) Initial Combination of Empagliflozin and Metformin in Patients With Type 2 Diabetes. Diabetes Care 39:10, pages 1718-1728.
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Kun-Ho Yoon, Rimei Nishimura, Jisoo Lee, Susanne Crowe, Afshin Salsali, Thomas Hach & Hans J. Woerle. (2016) Efficacy and safety of empagliflozin in patients with type 2 diabetes from Asian countries: pooled data from four phase III trials. Diabetes, Obesity and Metabolism 18:10, pages 1045-1049.
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Xueying Tan & Jingbo Hu. (2016) Empagliflozin/Linagliptin: Combination therapy in patients with type 2 diabetes. Annales d'Endocrinologie 77:5, pages 557-562.
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André J. Scheen. (2016) SGLT2 Inhibitors: Benefit/Risk Balance. Current Diabetes Reports 16:10.
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Aki Okamoto, Hirohide Yokokawa, Hironobu Sanada & Toshio Naito. (2016) Changes in Levels of Biomarkers Associated with Adipocyte Function and Insulin and Glucagon Kinetics During Treatment with Dapagliflozin Among Obese Type 2 Diabetes Mellitus Patients. Drugs in R&D 16:3, pages 255-261.
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Matthias H. Tschöp, Brian Finan, Christoffer Clemmensen, Vasily Gelfanov, Diego Perez-Tilve, Timo D. Müller & Richard D. DiMarchi. (2016) Unimolecular Polypharmacy for Treatment of Diabetes and Obesity. Cell Metabolism 24:1, pages 51-62.
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Sho-ichi YamagishiTakanori Matsui. (2016) Protective Role of Sodium–Glucose Co-Transporter 2 Inhibition Against Vascular Complications in Diabetes. Rejuvenation Research 19:2, pages 107-114.
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Serena Tonstad, Stephan Rössner, Aila Rissanen & Arne Astrup. (2016) Medical management of obesity in Scandinavia 2016. Obesity Medicine 1, pages 38-44.
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Rachel M. Saroka, Michael P. Kane, Robert S. Busch, Jay. Watsky & Robert A. Hamilton. (2015) SGLT-2 Inhibitor Therapy Added to GLP-1 Agonist Therapy in the Management of T2DM. Endocrine Practice 21:12, pages 1315-1322.
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Xiang-Yang Liu, Ning Zhang, Rui Chen, Jia-Guo Zhao & Pei Yu. (2015) Efficacy and safety of sodium–glucose cotransporter 2 inhibitors in type 2 diabetes: a meta-analysis of randomized controlled trials for 1 to 2 years. Journal of Diabetes and its Complications 29:8, pages 1295-1303.
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Andrew Lewin, Ralph A. DeFronzo, Sanjay PatelDacheng Liu, Renee Kaste, Hans J. Woerle & Uli C. Broedl. (2015) Initial Combination of Empagliflozin and Linagliptin in Subjects With Type 2 Diabetes. Diabetes Care 38:3, pages 394-402.
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Ralph A. DeFronzo, Andrew Lewin, Sanjay PatelDacheng Liu, Renee Kaste, Hans J. Woerle & Uli C. Broedl. (2015) Combination of Empagliflozin and Linagliptin as Second-Line Therapy in Subjects With Type 2 Diabetes Inadequately Controlled on Metformin. Diabetes Care 38:3, pages 384-393.
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Karel Kostev, Juliana Rex, Timo Rockel & Christina Heilmaier. (2015) Effects of selected antidiabetics on weight loss – A retrospective database analysis. Primary Care Diabetes 9:1, pages 74-77.
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André J. Scheen. (2014) Pharmacodynamics, Efficacy and Safety of Sodium–Glucose Co-Transporter Type 2 (SGLT2) Inhibitors for the Treatment of Type 2 Diabetes Mellitus. Drugs 75:1, pages 33-59.
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A.J. Scheen & N. Paquot. (2014) Metabolic effects of SGLT-2 inhibitors beyond increased glucosuria: A review of the clinical evidence. Diabetes & Metabolism 40:6, pages S4-S11.
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Greg L. Plosker. (2014) Dapagliflozin: A Review of Its Use in Patients with Type 2 Diabetes. Drugs 74:18, pages 2191-2209.
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André J Scheen & Luc F Van Gaal. (2014) Combating the dual burden: therapeutic targeting of common pathways in obesity and type 2 diabetes. The Lancet Diabetes & Endocrinology 2:11, pages 911-922.
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Martin Ridderstråle, Knut Robert Andersen, Cordula Zeller, Gabriel Kim, Hans J Woerle & Uli C Broedl. (2014) Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. The Lancet Diabetes & Endocrinology 2:9, pages 691-700.
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Menghan Liu, Magdalene K. Montgomery, Corrine E. Fiveash, Brenna Osborne, Gregory J. Cooney, Kim Bell-Anderson & Nigel Turner. (2014) PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis. Scientific Reports 4:1.
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Greg L. Plosker. (2014) Canagliflozin: A Review of Its Use in Patients with Type 2 Diabetes Mellitus. Drugs 74:7, pages 807-824.
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