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Future Medicinal Chemistry Volume 6, 2014 - Issue 11
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Perspective

The Essential Roles of Chemistry in High-Throughput Screening Triage

Jayme L Dahlin1 Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN55905, USA;2 Medical Scientist Training Program, Mayo Clinic College of Medicine, Rochester, MN55905, USAView further author information
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Michael A Walters3 Institute for Therapeutics Discovery & Development, University of Minnesota, Minneapolis, MN55414, USACorrespondence[email protected]
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Pages 1265-1290 | Published online: 27 Aug 2014

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Vanessa Martins, Lynsey Fazal, Aram Oganesian, Alpesh Shah, Jessie Stow, Hugh Walton & Nicola Wilsher. (2022) A commentary on the use of pharmacoenhancers in the pharmaceutical industry and the implication for DMPK drug discovery strategies. Xenobiotica 52:8, pages 786-796.
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Xiangyan Yi, Lian Xue, Tim Thomas & Jonathan B Baell. (2020) Action Plan for Hit Identification (APHID): KAT6A As a Case Study. Future Medicinal Chemistry 12:5, pages 423-437.
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Olivia Slater & Maria Kontoyianni. (2019) The compromise of virtual screening and its impact on drug discovery. Expert Opinion on Drug Discovery 14:7, pages 619-637.
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Martin Klumpp. (2016) Non-stoichiometric inhibition in integrated lead finding – a literature review. Expert Opinion on Drug Discovery 11:2, pages 149-162.
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Hairong Zhang, Qian Wu & Mikhail Y Berezin. (2015) Fluorescence anisotropy (polarization): from drug screening to precision medicine. Expert Opinion on Drug Discovery 10:11, pages 1145-1161.
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Philip Jones, Stuart McElroy, Angus Morrison & Andrew Pannifer. (2015) The Importance of Triaging in Determining the Quality of Output from High-Throughput Screening. Future Medicinal Chemistry 7:14, pages 1847-1852.
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John Spencer & Hannah Coaker. (2015) Highlights from Selectbio 2015: Academic Drug Discovery Conference, Cambridge, UK, 19–20 May 2015. Future Medicinal Chemistry 7:14, pages 1839-1842.
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