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Research Paper

Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells

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Pages 1571-1582 | Received 11 Apr 2014, Accepted 16 Aug 2014, Published online: 16 Dec 2014

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Pavla Röselová, Adam Obr, Aleš Holoubek, Dana Grebeňová & Kateřina Kuželová. (2018) Adhesion structures in leukemia cells and their regulation by Src family kinases. Cell Adhesion & Migration 12:3, pages 286-298.
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Articles from other publishers (15)

Rumeysa Ozyurt & Bulent Ozpolat. (2023) Therapeutic Landscape of AXL Receptor Kinase in Triple-Negative Breast Cancer. Molecular Cancer Therapeutics 22:7, pages 818-832.
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Hao Li, Luqi Li, Xun Qiu, Jing Zhang & Zichun Hua. (2023) The interaction of CFLAR with p130Cas promotes cell migration. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1870:2, pages 119390.
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Sutapa Sinha, Charla R. Secreto, Justin C. Boysen, Connie Lesnick, Zhiquan Wang, Wei Ding, Timothy G. Call, Saad J. Kenderian, Sameer A. Parikh, Steven L. Warner, David J. Bearss, Asish K. Ghosh & Neil E. Kay. (2021) Upregulation of AXL and β-catenin in chronic lymphocytic leukemia cells cultured with bone marrow stroma cells is associated with enhanced drug resistance. Blood Cancer Journal 11:2.
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Tanguy Lechertier, Louise E. Reynolds, Hyojin Kim, Ana Rita Pedrosa, Jesús Gómez-Escudero, José M. Muñoz-Félix, Silvia Batista, Matthew Dukinfield, Fevzi Demircioglu, Ping Pui Wong, Kylie P. Matchett, Neil C. Henderson, Gabriela D’Amico, Maddy Parsons, Catherine Harwood, Pascal Meier & Kairbaan M. Hodivala-Dilke. (2020) Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nature Communications 11:1.
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Markus Lauter, Anja Weber & Robert Torka. (2019) Targeting of the AXL receptor tyrosine kinase by small molecule inhibitor leads to AXL cell surface accumulation by impairing the ubiquitin-dependent receptor degradation. Cell Communication and Signaling 17:1.
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Lilian Zsákai, Anna Sipos, Judit Dobos, Dániel Erős, Csaba Szántai-Kis, Péter Bánhegyi, János Pató, László Őrfi, Zsolt Matula, Gábor Mikala, György Kéri, István Peták & István Vályi-Nagy. (2019) Targeted drug combination therapy design based on driver genes. Oncotarget 10:51, pages 5255-5266.
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Imane Naboulsi, Aziz Aboulmouhajir, Lamfeddal Kouisni, Faouzi Bekkaoui & Abdelaziz Yasri. (2018) Combining a QSAR Approach and Structural Analysis to Derive an SAR Map of Lyn Kinase Inhibition. Molecules 23:12, pages 3271.
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István Szabadkai, Robert Torka, Rita Garamvölgyi, Ferenc Baska, Pál Gyulavári, Sándor Boros, Eszter Illyés, Axel Choidas, Axel Ullrich & László Őrfi. (2018) Discovery of N -[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors . Journal of Medicinal Chemistry 61:14, pages 6277-6292.
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Sai Kundur, Hung Nguyen, Lloyd McKee, Clairissa Cruz, Ponniah Selvakumar & Ashakumary Lakshmikuttyamma. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 2888 2893 .
Rihan El Bezawy, Michelandrea De Cesare, Marzia Pennati, Marcello Deraco, Paolo Gandellini, Valentina Zuco & Nadia Zaffaroni. (2017) Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism. Journal of Hematology & Oncology 10:1.
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Christine Baumann, Axel Ullrich & Robert Torka. (2017) GAS 6‐expressing and self‐sustaining cancer cells in 3D spheroids activate the PDK ‐ RSK ‐ mTOR pathway for survival and drug resistance . Molecular Oncology 11:10, pages 1430-1447.
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Hoin Kang, Jun Gi Rho, Chongtae Kim, Hyosun Tak, Heejin Lee, Eunbyul Ji, Sojin Ahn, A-Ri Shin, Hyun-Il Cho, Yun Hyun Huh, Woo Keun Song, Wook Kim & Eun Kyung Lee. (2017) The miR-24-3p/p130Cas: a novel axis regulating the migration and invasion of cancer cells. Scientific Reports 7:1.
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Sai Kundur, Hung Nguyen, Lloyd McKee, Clairissa Cruz, Ponniah Selvakumar & Ashakumary Lakshmikuttyamma. 2017. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 1 6 .
Ian Dransfield & Sarah Farnworth. 2016. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy 113 132 .
Katia Rea, Patrizia Pinciroli, Marialuisa Sensi, Federica Alciato, Brigitte Bisaro, Ludmila Lozneanu, Francesco Raspagliesi, Floriana Centritto, Sara Cabodi, Paola Defilippi, Gian Carlo Avanzi, Silvana Canevari & Antonella Tomassetti. (2015) Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome. Oncotarget 6:31, pages 30859-30875.
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