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Gefitinib, Methotrexate and Methotrexate plus 5-Fluorouracil as palliative treatment in recurrent head and neck squamous cell carcinoma

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Pages 346-351 | Received 05 Jul 2014, Accepted 01 Sep 2014, Published online: 10 Mar 2015

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Akhil Rajendra, Vanita Noronha, Amit Joshi, Vijay Maruti Patil, Nandini Menon & Kumar Prabhash. (2020) Palliative chemotherapy in head and neck cancer: balancing between beneficial and adverse effects. Expert Review of Anticancer Therapy 20:1, pages 17-29.
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H. Boyes, J. Barraclough, R. Ratansi, S.N. Rogers & A. Kanatas. (2018) Structured review of the patient-reported outcome instruments used in clinical trials in head and neck surgery. British Journal of Oral and Maxillofacial Surgery 56:3, pages 161-167.
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Stefan Hartmann, Norbert Neckel, Axel Seher, Grit Mutzbauer, Roman C. Brands, Christian Linz, Alexander C. Kübler & Urs D. A. Müller-Richter. (2015) Erlotinib and gefitinib responsiveness in head and neck cancer cell lines—a comparing analysis with cetuximab. Clinical Oral Investigations 20:4, pages 759-769.
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