Cancer Biology & Therapy, Volume 16, Issue 2 (2015)

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Cancer Biology & Therapy, Volume 16, Issue 2 (2015)

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Letters to the Editor

Letter
Targeting FOXM1 auto-regulation in cancer
Andrei L Gartel
Pages: 185-186
Published online: 10 Mar 2015
CitationforTargeting FOXM1 auto-regulation in cancer | Full Text | References | PDF (44.2 KB)
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Letter
Are there alternative ways to quantify the real benefit of novel agents in oncology? – the ‘death pace’
Vincenzo Formica, Eugenio Montefusco & Mario Roselli
Pages: 187-188
Published online: 10 Mar 2015
CitationforAre there alternative ways to quantify the real benefit of novel agents in oncology? – the ‘death pace’ | Full Text | References | PDF (248.5 KB)
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Review

Beyond the histone tale: HP1α deregulation in breast cancer epigenetics
Johan Vad-Nielsen & Anders Lade Nielsen
Pages: 189-200
Published online: 10 Mar 2015
AbstractforBeyond the histone tale: HP1α deregulation in breast cancer epigenetics | Full Text | References | PDF (536.2 KB)
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Journal Clubs

Article
Enzalutamide for treatment of CRPC: Rationale for sequencing and potential clinical biomarker for resistance
Sarah E Lochrin, William D Figg II & Stephen P Finn
Pages: 201-203
Published online: 10 Mar 2015
AbstractforEnzalutamide for treatment of CRPC: Rationale for sequencing and potential clinical biomarker for resistance | Full Text | References | PDF (59.2 KB)
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Article
Targeted PI3Kδ inhibition by the small molecule idelalisib as a novel therapy in indolent non-Hodgkin lymphoma
Tracy C Okoli, Cody J Peer, Kieron Dunleavy & William D Figg
Pages: 204-206
Published online: 10 Mar 2015
AbstractforTargeted PI3Kδ inhibition by the small molecule idelalisib as a novel therapy in indolent non-Hodgkin lymphoma | Full Text | References | PDF (64.3 KB)
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Article
Dexamethasone may be the most efficacious corticosteroid for use as monotherapy in castration-resistant prostate cancer
S L Holder, J Drabick, J Zhu & M Joshi
Pages: 207-209
Published online: 10 Mar 2015
AbstractforDexamethasone may be the most efficacious corticosteroid for use as monotherapy in castration-resistant prostate cancer | Full Text | References | PDF (59.7 KB)
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Bedside to Bench Reports

Article
Metformin: a modulator of bevacizumab activity in cancer? A case report
Stefano Indraccolo, Giovanni Randon, Elisabetta Zulato, Margherita Nardin, Camillo Aliberti, Fabio Pomerri, Alessandra Casarin & Maria Ornella Nicoletto
Pages: 210-214
Published online: 10 Mar 2015
AbstractforMetformin: a modulator of bevacizumab activity in cancer? A case report | Full Text | References | PDF (417.1 KB)
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Article
Clinical observation of liver cancer patients treated with axitinib and cabozantinib after failed sorafenib treatment: a case report and literature review
Bin Zhang, Xia Zhang, Tao Zhou & Jiwei Liu
Pages: 215-218
Published online: 10 Mar 2015
AbstractforClinical observation of liver cancer patients treated with axitinib and cabozantinib after failed sorafenib treatment: a case report and literature review | Full Text | References | PDF (195.8 KB)
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Clinical Studies

Article
PTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target
Buddha Gurung, Xianxin Hua, Melissa Runske, Bonita Bennett, Virginia LiVolsi, Robert Roses, Douglas A Fraker & David C Metz
Pages: 219-224
Published online: 10 Mar 2015
AbstractforPTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target | Full Text | References | PDF (220.6 KB)
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Article
A phase II trial of biweekly vinorelbine and oxaliplatin in second- or third-line metastatic triple-negative breast cancer
Jian Zhang, Leiping Wang, Zhonghua Wang, Xichun Hu, Biyun Wang, Jun Cao, Fangfang Lv, Chunlei Zhen, Sheng Zhang & Zhimin Shao
Pages: 225-232
Published online: 10 Mar 2015
AbstractforA phase II trial of biweekly vinorelbine and oxaliplatin in second- or third-line metastatic triple-negative breast cancer | Full Text | References | PDF (210.8 KB)
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Research Papers

Article
Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells
Daniel R Premkumar, Esther P Jane & Ian F Pollack
Pages: 233-243
Published online: 10 Mar 2015
AbstractforCucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells | Full Text | References | PDF (1 MB)
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Article
Factor inhibiting HIF1α (FIH-1) functions as a tumor suppressor in human colorectal cancer by repressing HIF1α pathway
Tao Chen, Zhong Ren, Le-Chi Ye, Ping-Hong Zhou, Jian-Min Xu, Qiang Shi, Li-Qing Yao & Yun-Shi Zhong
Pages: 244-252
Published online: 10 Mar 2015
AbstractforFactor inhibiting HIF1α (FIH-1) functions as a tumor suppressor in human colorectal cancer by repressing HIF1α pathway | Full Text | References | PDF (1,017 KB)
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Article
Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer
Satsuki Mashiko, Kazuyuki Kitatani, Masafumi Toyoshima, Atsuhiko Ichimura, Takashi Dan, Toshinori Usui, Masumi Ishibashi, Shogo Shigeta, Satoru Nagase, Toshio Miyata & Nobuo Yaegashi
Pages: 253-260
Published online: 10 Mar 2015
AbstractforInhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer | Full Text | References | PDF (633.4 KB)
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Article
MiR-1204 sensitizes nasopharyngeal carcinoma cells to paclitaxel both in vitro and in vivo
Xiaowei Peng, Peiguo Cao, Jingjing Li, Dong He, Shuang Han, Jianda Zhou, Guolin Tan, Wei Li, Fenghui Yu, Jianjun Yu, Zan Li & Ke Cao
Pages: 261-267
Published online: 10 Mar 2015
AbstractforMiR-1204 sensitizes nasopharyngeal carcinoma cells to paclitaxel both in vitro and in vivo | Full Text | References | PDF (603.1 KB)
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Article
Plasma miR-183 predicts recurrence and prognosis in patients with colorectal cancer
Dawei Yuan, Kang Li, Kun Zhu, Rong Yan & Chengxue Dang
Pages: 268-275
Published online: 10 Mar 2015
AbstractforPlasma miR-183 predicts recurrence and prognosis in patients with colorectal cancer | Full Text | References | PDF (366.7 KB)
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Article
EGFR signaling defines Mcl-1 survival dependency in neuroblastoma
Srilatha Nalluri, Susan K Peirce, Rachel Tanos, Haneen A Abdella, Dipan Karmali, Michael D Hogarty & Kelly C Goldsmith
Pages: 276-286
Published online: 10 Mar 2015
AbstractforEGFR signaling defines Mcl-1 survival dependency in neuroblastoma | Full Text | References | PDF (841.9 KB)
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Article
NDRG2 acts as a negative regulator downstream of androgen receptor and inhibits the growth of androgen-dependent and castration-resistant prostate cancer
Chuigong Yu, Guojun Wu, Ruixiao Li, Lei Gao, Fan Yang, Yi Zhao, Jian Zhang, Rui Zhang, Jing Zhang, Libo Yao, Jianlin Yuan & Xia Li
Pages: 287-296
Published online: 10 Mar 2015
AbstractforNDRG2 acts as a negative regulator downstream of androgen receptor and inhibits the growth of androgen-dependent and castration-resistant prostate cancer | Full Text | References | PDF (1,007.5 KB)
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Article
PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism
Ning Li, Junfang Qin, Lan Lan, Hongyao Zhang, Fang Liu, Zhaozhen Wu, Hong Ni & Yue Wang
Pages: 297-306
Published online: 10 Mar 2015
AbstractforPTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism | Full Text | References | PDF (903.8 KB)
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Article
Involvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT2R agonist effectively attenuates growth of PDAC grafts in mice
Susumu Ishiguro, Kiyoshi Yoshimura, Ryouichi Tsunedomi, Masaaki Oka, Sonshin Takao, Makoto Inui, Atsushi Kawabata, Terrahn Wall, Vassiliki Magafa, Paul Cordopatis, Andreas G Tzakos & Masaaki Tamura
Pages: 307-316
Published online: 10 Mar 2015
AbstractforInvolvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT2R agonist effectively attenuates growth of PDAC grafts in mice | Full Text | References | PDF (624.2 KB) | Supplemental
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Article
Network-based approach to identify prognostic biomarkers for estrogen receptor–positive breast cancer treatment with tamoxifen
Rong Liu, Cheng-Xian Guo & Hong-Hao Zhou
Pages: 317-324
Published online: 10 Mar 2015
AbstractforNetwork-based approach to identify prognostic biomarkers for estrogen receptor–positive breast cancer treatment with tamoxifen | Full Text | References | PDF (392.2 KB) | Supplemental
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Article
Crosstalk between PI3K and Ras pathways via protein phosphatase 2A in human ovarian clear cell carcinoma
Masaaki Takai, Takatoshi Nakagawa, Akiko Tanabe, Yoshito Terai, Masahide Ohmichi & Michio Asahi
Pages: 325-335
Published online: 10 Mar 2015
AbstractforCrosstalk between PI3K and Ras pathways via protein phosphatase 2A in human ovarian clear cell carcinoma | Full Text | References | PDF (833 KB)
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Article
Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma
Yashwanth Subbannayya, Nazia Syed, Mustafa A Barbhuiya, Remya Raja, Arivusudar Marimuthu, Nandini Sahasrabuddhe, Sneha M Pinto, Srikanth Srinivas Manda, Santosh Renuse, HC Manju, Mohammed Abdul Lateef Zameer, Jyoti Sharma, Mariana Brait, Kotteazeth Srikumar, Juan Carlos Roa, M Vijaya Kumar, KV Veerendra Kumar, TS Keshava Prasad, Girija Ramaswamy, Rekha Vijay Kumar, Akhilesh Pandey, Harsha Gowda & Aditi Chatterjee
Pages: 336-345
Published online: 10 Mar 2015
AbstractforCalcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma | Full Text | References | PDF (878.5 KB) | Supplemental
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Reports

Article
Gefitinib, Methotrexate and Methotrexate plus 5-Fluorouracil as palliative treatment in recurrent head and neck squamous cell carcinoma
Vandana Singh Kushwaha, Seema Gupta, Nuzhat Husain, Huma Khan, MPS Negi, Naseem Jamal & Ashim Ghatak
Pages: 346-351
Published online: 10 Mar 2015
AbstractforGefitinib, Methotrexate and Methotrexate plus 5-Fluorouracil as palliative treatment in recurrent head and neck squamous cell carcinoma | Full Text | References | PDF (327.2 KB)
  • 1490 Views
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