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Bustanur Rosidi, Diana Priyatno, Teguh Pribadi Putra & Irawan Yusuf. (2023) Metformin Induces a Caspase 3-Unrelated Apoptosis in Human Colorectal Cancer Cell Lines HCT116 and SW620. Cancer Management and Research 15, pages 475-485.
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Weiling Leng, Juan Jiang, Bing Chen & Qinan Wu. (2021) Metformin and Malignant Tumors: Not Over the Hill. Diabetes, Metabolic Syndrome and Obesity 14, pages 3673-3689.
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Jing Zhang, Liping Wen, Quan Zhou, Kuifeng He & Lisong Teng. (2020) Preventative and Therapeutic Effects of Metformin in Gastric Cancer: A New Contribution of an Old Friend. Cancer Management and Research 12, pages 8545-8554.
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ME Naffaa, V Rosenberg, A Watad, S Tiosano, Y Yavne, G Chodick, H Amital & V Shalev. (2020) Adherence to metformin and the onset of rheumatoid arthritis: a population-based cohort study. Scandinavian Journal of Rheumatology 49:3, pages 173-180.
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Zhuang Luo, Tingting Zhu, Wei Luo, Yuanyuan Lv, Liyan Zhang, Chu Wang, Min Li, Wenjuan Wu & Shaoqing Shi. (2019) Metformin induces apoptotic cytotoxicity depending on AMPK/PKA/GSK-3β-mediated c-FLIPL degradation in non-small cell lung cancer. Cancer Management and Research 11, pages 681-689.
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Yanmin Wang, Yanli Meng, Shijun Zhang, Huancheng Wu, Dawei Yang, Chaohui Nie & Qunliang Hu. (2018) Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo. OncoTargets and Therapy 11, pages 6039-6048.
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Yuanteng Zhang, Zizheng Gao, Zezheng Pan, Huangxi Fu, Feng Jiang, Hao Yan, Bo Yang, Qiaojun He, Peihua Luo, Zhifei Xu & Xiaochun Yang. (2023) Crizotinib induces pulmonary toxicity by blocking autophagy flux in alveolar epithelial cells. Biochemical Pharmacology 215, pages 115636.
Crossref
Crossref
Xiaofang Wang, Hui Wang, Panpan Yi, Coleman Baker, Gonzales Casey, Xuping Xie, Huanle Luo, Jiyang Cai, Xuegong Fan, Lynn Soong, Haitao Hu, Pei-Yong Shi, Yuejin Liang & Jiaren Sun. (2023) Metformin restrains ZIKV replication and alleviates virus-induced inflammatory responses in microglia. International Immunopharmacology 121, pages 110512.
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Crossref
Masafumi Ono, Koji Fujita, Kiyoyuki Kobayashi & Tsutomu Masaki. (2023) Influence of diabetes mellitus and effectiveness of metformin on hepatocellular carcinoma. Hepatology Research 53:7, pages 579-594.
Crossref
Crossref
Long-Yao Zhang, Yu-Hua Yin & Xue-Jian Wang. (2023) Advances in the mechanism of action of metformin in pituitary tumors. World Journal of Meta-Analysis 11:5, pages 144-150.
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Mehdi Sanati, Samaneh Aminyavari, Hamid Mollazadeh, Ali Motamed-Sanaye, Bahram Bibak, Elmira Mohtashami, Yong Teng, Amir R. Afshari & Amirhossein Sahebkar. (2023) The Potential Therapeutic Impact of Metformin in Glioblastoma
Multiforme. Current Medicinal Chemistry 30:7, pages 857-877.
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Reihaneh Fatehi, Marzieh Rashedinia, Amin Reza Akbarizadeh, Mozhdeh zamani & Negar Firouzabadi. (2023) Metformin enhances anti-cancer properties of resveratrol in MCF-7 breast cancer cells via induction of apoptosis, autophagy and alteration in cell cycle distribution. Biochemical and Biophysical Research Communications 644, pages 130-139.
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Rajalakshmi Manikkam, Vijayalakshmi Periyasamy & Indu Sabapathy. 2023. Computational Methods in Drug Discovery and Repurposing for Cancer Therapy. Computational Methods in Drug Discovery and Repurposing for Cancer Therapy
201
222
.
Xiao-yu Wu, Wen-Wen Xu, Xiang-kun Huan, Guan-nan Wu, Gang Li, Yu-Hong Zhou & Masoud Najafi. (2022) Mechanisms of cancer cell killing by metformin: a review on different cell death pathways. Molecular and Cellular Biochemistry 478:1, pages 197-214.
Crossref
Crossref
Marina Leite, Raquel Seruca & Jorge M. Gonçalves. 2023. Hereditary Gastric and Breast Cancer Syndrome. Hereditary Gastric and Breast Cancer Syndrome
281
320
.
Diana Araújo, Eduarda Ribeiro, Irina Amorim & Nuno Vale. (2022) Repurposed Drugs in Gastric Cancer. Molecules 28:1, pages 319.
Crossref
Crossref
Hang Qian, Dong Wang, Binfeng He, Qian Liu, Yu Xu, Di Wu, Chunfa Chen, Wen Zhang, David Tai Leong & Guansong Wang. (2022) Assembling defined DNA nanostructures with anticancer drugs: a metformin/DNA complex nanoplatform with a synergistic antitumor effect for KRAS-mutated lung cancer therapy. NPG Asia Materials 14:1.
Crossref
Crossref
Wen-Hsi Lan, Ting-Yu Lin, Jia-Ai Yeh, Chun-Lung Feng, Jun-Te Hsu, Hwai-Jeng Lin, Chia-Jung Kuo & Chih-Ho Lai. (2022) Mechanism Underlying Metformin Action and Its Potential to Reduce Gastric Cancer Risk. International Journal of Molecular Sciences 23:22, pages 14163.
Crossref
Crossref
Wasita Witayateeraporn, Hien Minh Nguyen, Duc Viet Ho, Hoai Thi Nguyen, Pithi Chanvorachote, Chanida Vinayanuwattikun & Varisa Pongrakhananon. (2022) Aspiletrein A Induces Apoptosis Cell Death via Increasing Reactive Oxygen Species Generation and AMPK Activation in Non-Small-Cell Lung Cancer Cells. International Journal of Molecular Sciences 23:16, pages 9258.
Crossref
Crossref
K. O. Kuznetsov, E. R. Safina, D. V. Gaimakova, Ya. S. Frolova, I. Yu. Oganesyan, A. G. Sadertdinova, K. A. Nazmieva, A. H. Islamgulov, A. R. Karimova, A. M. Galimova & E. V. Rizvanova. (2022) Metformin and malignant neoplasms: a possible mechanism of antitumor action and prospects for use in practice. Problems of Endocrinology 68:5, pages 45-55.
Crossref
Crossref
Ka Shing Cheung, Kit Lam Chung & Wai K. Leung. (2022) Chemopreventive Effect of Metformin on Gastric Cancer Development. Gut and Liver 16:2, pages 147-156.
Crossref
Crossref
Feng Huang, Yuan Xiang, Ting Li, You Huang, Jun Wang, Hui-Min Zhang, Han-Han Li, Zhou-Tong Dai, Jia-Peng Li, Hui Li, Jun Zhou & Xing-Hua Liao. (2022) Metformin and MiR-365 synergistically promote the apoptosis of gastric cancer cells via MiR-365-PTEN-AMPK axis. Pathology - Research and Practice 230, pages 153740.
Crossref
Crossref
Yuying Fan, Xiaoli Ren, Yingxue Wang, Enshuang Xu, Shuang Wang, Ruidong Ge & Yun Liu. (2021)
Metformin inhibits the proliferation of canine mammary gland tumor cells through the AMPK/AKT/mTOR signaling pathway
in vitro
. Oncology Letters 22:6.
Crossref
Crossref
Mennatallah Ghouraba, Razan Masad, Eric Mpingirika, Omnia Abdelraheem, Rached Zeghlache, Aya Alserw & Asma Amleh. (2021) Role of NELF‑B in supporting epithelial‑mesenchymal transition and cell proliferation during hepatocellular carcinoma progression. Oncology Letters 22:5.
Crossref
Crossref
Hui-Hwa Tseng, You-Zuo Chen, Nan-Hua Chou, Yen-Chih Chen, Chao-Chuan Wu, Li-Feng Liu, Yi-Fang Yang, Chung-Yu Yeh, Mei-Lang Kung, Ya-Ting Tu & Kuo-Wang Tsai. (2021) Metformin inhibits gastric cancer cell proliferation by regulation of a novel Loc100506691-CHAC1 axis. Molecular Therapy - Oncolytics 22, pages 180-194.
Crossref
Crossref
Madhuri Shende Warkad, Chea-Ha Kim, Beom-Goo Kang, Soo-Hyun Park, Jun-Sub Jung, Jing-Hui Feng, Gozde Inci, Sung-Chan Kim, Hong-Won Suh, Soon Sung Lim & Jae-Yong Lee. (2021) Metformin-induced ROS upregulation as amplified by apigenin causes profound anticancer activity while sparing normal cells. Scientific Reports 11:1.
Crossref
Crossref
Mohammad rafi Khezri, Hassan Malekinejad, Naime Majidi-Zolbanin & Morteza Ghasemnejad-Berenji. (2021) Anticancer potential of metformin: focusing on gastrointestinal cancers. Cancer Chemotherapy and Pharmacology 87:5, pages 587-598.
Crossref
Crossref
Andrea Giaccari, Anna Solini, Simona Frontoni & Stefano Del Prato. (2021) Metformin Benefits: Another Example for Alternative Energy Substrate Mechanism?. Diabetes Care 44:3, pages 647-654.
Crossref
Crossref
Shenghan Lou, Jian Zhang, Zhao Zhai, Xin Yin, Yimin Wang, Tianyi Fang & Yingwei Xue. (2021) The landscape of alternative splicing reveals novel events associated with tumorigenesis and the immune microenvironment in gastric cancer. Aging 13:3, pages 4317-4334.
Crossref
Crossref
Józef Drzewoski & Markolf Hanefeld. (2021) The Current and Potential Therapeutic Use of Metformin—The Good Old Drug. Pharmaceuticals 14:2, pages 122.
Crossref
Crossref
Jiahong Chen, Yaqiang Huang, Zhenfeng Tang, Maozhang Li, Xiaohui Ling, Jinxian Liao, Xiaobo Zhou, Shumin Fang, Haibo Zhao, Weide Zhong & Xia Yuan. (2021) Genome-Scale CRISPR-Cas9 Transcriptional Activation Screening in Metformin Resistance Related Gene of Prostate Cancer. Frontiers in Cell and Developmental Biology 8.
Crossref
Crossref
Shangze Jiang & Qingjun Lu. (2021) A new contribution for an old drug: Prospect of metformin in colorectal oncotherapy. Journal of Cancer Research and Therapeutics 17:7, pages 1608.
Crossref
Crossref
Mi Hee Cho, Tae Gon Yoo, Su-Min Jeong & Dong Wook Shin. (2021) Association of Aspirin, Metformin, and Statin Use with Gastric Cancer Incidence and Mortality: A Nationwide Cohort Study. Cancer Prevention Research 14:1, pages 95-104.
Crossref
Crossref
Anuradha Kirtonia, Kavita Gala, Stina George Fernandes, Gouri Pandya, Amit Kumar Pandey, Gautam Sethi, Ekta Khattar & Manoj Garg. (2021) Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics. Seminars in Cancer Biology 68, pages 258-278.
Crossref
Crossref
Bahman Moradipoodeh, Ghorban Mohammadzadeh, Davood Neamati, Mahdieh Koushki, Rahim Moradi, Anise Kiashi & Fatemeh Ahmadpour. (2020) Synergistic Effects of Metformin-Lapatinib Combination on the Expression of Bax in SK-BR3 Cells. Jentashapir Journal of Cellular and Molecular Biology 11:4.
Crossref
Crossref
Liangyu Cai, Xin Jin, Jiannan Zhang, Le Li & Jinfeng Zhao. (2020) Metformin suppresses Nrf2-mediated chemoresistance in hepatocellular carcinoma cells by increasing glycolysis. Aging 12:17, pages 17582-17600.
Crossref
Crossref
Y. Shuai, C. Li & X. Zhou. (2020) The effect of metformin on gastric cancer in patients with type 2 diabetes: a systematic review and meta-analysis. Clinical and Translational Oncology 22:9, pages 1580-1590.
Crossref
Crossref
Elham Asa, Rahil Janatifar, Atefeh Verdi, Marzeye Alavisoltani & Masoumeh Janbazi. (2020) Effect of Alpha-Lipoic Acid on Blood Hormonal Parameters and Follicular Fluid Oxidative Stress Factors in Infertile Women with Polycystic Ovary Syndrome Undergoing Intracytoplasmic Sperm Injection. Qom Univ Med Sci J 14:5, pages 49-58.
Crossref
Crossref
Fumihiro Terasaki, Teiichi Sugiura, Yukiyasu Okamura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi & Katsuhiko Uesaka. (2020) Oncological benefit of metformin in patients with pancreatic ductal adenocarcinoma and comorbid diabetes mellitus. Langenbeck's Archives of Surgery 405:3, pages 313-324.
Crossref
Crossref
Jianjun Wang, Yunchun Li, Qianfeng Ma & Jiaxin Huang. (2020) miR‑378 in combination with ultrasonic irradiation and SonoVue microbubbles transfection inhibits hepatoma cell growth. Molecular Medicine Reports.
Crossref
Crossref
Lin Tuo, Jin Xiang, Xuanming Pan, Jieli Hu, Hua Tang, Li Liang, Jie Xia, Yuan Hu, Wenlu Zhang, Ailong Huang, Kai Wang & Ni Tang. (2019) PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27Kip1 axis. Journal of Experimental & Clinical Cancer Research 38:1.
Crossref
Crossref
Xinyu Shao, Zhengwu Cheng, Menglin Xu, Jiading Mao, Junfeng Wang & Chunli Zhou. (2019) Prognosis, Significance and Positive Correlation of Rab1A and p-S6K/Gli1 Expression in Gastric Cancer. Anti-Cancer Agents in Medicinal Chemistry 19:11, pages 1359-1367.
Crossref
Crossref
Xiaoli Sun, Xinwu Zhang, Hongjun Zhai, Di Zhang & Shuangyu Ma. (2019) Chicoric acid (CA) induces autophagy in gastric cancer through promoting endoplasmic reticulum (ER) stress regulated by AMPK. Biomedicine & Pharmacotherapy 118, pages 109144.
Crossref
Crossref
Hao Wang, Ying‑Hua Luo, Gui‑Nan Shen, Xian‑Ji Piao, Wan‑Ting Xu, Yi Zhang, Jia‑Ru Wang, Yu‑Chao Feng, Jin‑Qian Li, Yu Zhang, Tong Zhang, Shi‑Nong Wang, Hui Xue, Hong‑Xing Wang, Chang‑Yuan Wang & Cheng‑Hao Jin. (2019) Two novel 1,4‑naphthoquinone derivatives induce human gastric cancer cell apoptosis and cell cycle arrest by regulating reactive oxygen species‑mediated MAPK/Akt/STAT3 signaling pathways. Molecular Medicine Reports.
Crossref
Crossref
Wanming Li, Shuo Wang, Linlin Zhou, Yajie Cheng & Jin Fang. (2019) An ssDNA aptamer selected by Cell-SELEX for the targeted imaging of poorly differentiated gastric cancer tissue. Talanta 199, pages 634-642.
Crossref
Crossref
Sarah Courtois, Philippe Lehours & Emilie Bessède. (2019) The therapeutic potential of metformin in gastric cancer. Gastric Cancer 22:4, pages 653-662.
Crossref
Crossref
Zhuang Luo, Wei Chen, Wenjuan Wu, Wei Luo, Tingting Zhu, Gang Guo, Liyan Zhang, Chu Wang, Min Li & Shaoqing Shi. (2019) Metformin promotes survivin degradation through AMPK/PKA/GSK‐3β‐axis in non–small cell lung cancer. Journal of Cellular Biochemistry 120:7, pages 11890-11899.
Crossref
Crossref
Jianwen Ye, Lei Qi, Kunlun Chen, Renfeng Li, Shengping Song, Chuang Zhou & Wenlong Zhai. (2019) Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo. International Journal of Oncology.
Crossref
Crossref
Davide Serrano, Bernardo Bonanni & Karen Brown. (2019) Therapeutic cancer prevention: achievements and ongoing challenges – a focus on breast and colorectal cancer. Molecular Oncology 13:3, pages 579-590.
Crossref
Crossref
Dong-Gi Mun, Jinhyuk Bhin, Sangok Kim, Hyunwoo Kim, Jae Hun Jung, Yeonjoo Jung, Ye Eun Jang, Jong Moon Park, Hokeun Kim, Yeonhwa Jung, Hangyeore Lee, Jingi Bae, Seunghoon Back, Su-Jin Kim, Jieun Kim, Heejin Park, Honglan Li, Kyu-Baek Hwang, Young Soo Park, Jeong Hwan Yook, Byung Sik Kim, Sun Young Kwon, Seung Wan Ryu, Do Youn Park, Tae Yong Jeon, Dae Hwan Kim, Jae-Hyuck Lee, Sang-Uk Han, Kyu Sang Song, Dongmin Park, Jun Won Park, Henry Rodriguez, Jaesang Kim, Hookeun Lee, Kwang Pyo Kim, Eun Gyeong Yang, Hark Kyun Kim, Eunok Paek, Sanghyuk Lee, Sang-Won Lee & Daehee Hwang. (2019) Proteogenomic Characterization of Human Early-Onset Gastric Cancer. Cancer Cell 35:1, pages 111-124.e10.
Crossref
Crossref
Li-Dong Zu, Xing-Chun Peng, Zhi Zeng, Jing-Long Wang, Li-Li Meng, Wei-Wei Shen, Chun-Ting Hu, Ye Yang & Guo-Hui Fu. (2018) Gastrin inhibits gastric cancer progression through activating the ERK-P65-miR23a/27a/24 axis. Journal of Experimental & Clinical Cancer Research 37:1.
Crossref
Crossref
Kai Jin, Lunliang Ruan, Jiujun Pu, Ailing Zhong, Fuchao Wang, Song Tan, Hua Huang, Jiamin Mu & Gang Yang. (2018) Metformin suppresses growth and adrenocorticotrophic hormone secretion in mouse pituitary corticotroph tumor AtT20 cells. Molecular and Cellular Endocrinology 478, pages 53-61.
Crossref
Crossref
Jiao Jiao Zhang, Huynh Luong Do, Nisansala Chandimali, Sang Baek Lee, Young Sun Mok, Nameun Kim, Seong Bong Kim, Taeho Kwon & Dong Kee Jeong. (2018) Non-thermal plasma treatment improves chicken sperm motility via the regulation of demethylation levels. Scientific Reports 8:1.
Crossref
Crossref
Olivia Lacroix, Alexandra Couttenier, Evelien Vaes, Chris R. Cardwell, Harlinde De Schutter & Annie Robert. (2018) Impact of metformin on gastric adenocarcinoma survival: A Belgian population based study. Cancer Epidemiology 53, pages 149-155.
Crossref
Crossref
Guiju Tang, Jianfeng Guo, Yapei Zhu, Zaiju Huang, Ting Liu, Jing Cai, Lili Yu & Zehua Wang. (2018) Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation. International Journal of Oncology.
Crossref
Crossref
Yue Deng & Weiyuan Ma. (2017) Metformin inhibits HaCaT cell viability via the miR-21/PTEN/Akt signaling pathway. Molecular Medicine Reports.
Crossref
Crossref
Wen-Tsung Huang, Yu-Hsuan Tsai, Shang-Hung Chen, Ching-Wen Kuo, Yao-Lung Kuo, Kuo-Ting Lee, Wen-Chung Chen, Pei Chih Wu, Chun-Yu Chuang, Siao Muk Cheng, Chun-Hui Lin, Euphemia Yee Leung, Yung-Chieh Chang & Chun Hei Antonio Cheung. (2017) HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells. Frontiers in Pharmacology 8.
Crossref
Crossref
Amr Ahmed EL-Arabey. (2017) New insight for metformin against bladder cancer. Genes and Environment 39:1.
Crossref
Crossref
Yong Lei, Yanhua Yi, Yang Liu, Xia Liu, Evan T. Keller, Chao-Nan Qian, Jian Zhang & Yi Lu. (2017) Metformin targets multiple signaling pathways in cancer. Chinese Journal of Cancer 36:1.
Crossref
Crossref
Peiwen Li, Cong Zhang, Peng Gao, Xiaowan Chen, Bin Ma, Dehao Yu, Yongxi Song & Zhenning Wang. (2017) Metformin use and its effect on gastric cancer in patients with type 2 diabetes: A systematic review of observational studies. Oncology Letters.
Crossref
Crossref
Yuki Kunisada, Shingo Eikawa, Nahoko Tomonobu, Shohei Domae, Takenori Uehara, Shohei Hori, Yukihiro Furusawa, Koji Hase, Akira Sasaki & Heiichiro Udono. (2017) Attenuation of CD4+CD25+ Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug. EBioMedicine 25, pages 154-164.
Crossref
Crossref
Brandy M. Heckman-Stoddard, Andrea DeCensi, Vikrant V. Sahasrabuddhe & Leslie G. Ford. (2017) Repurposing metformin for the prevention of cancer and cancer recurrence. Diabetologia 60:9, pages 1639-1647.
Crossref
Crossref
Victor Constante Oliveira, Sarah Alves Rodrigues Constante, Priscila Capelari Orsolin, Júlio César Nepomuceno, Alexandre Azenha Alves de Rezende & Mário Antônio Spanó. (2017) Modulatory effects of metformin on mutagenicity and epithelial tumor incidence in doxorubicin-treated Drosophila melanogaster. Food and Chemical Toxicology 106, pages 283-291.
Crossref
Crossref
Jin-Lai Wei, Min Fang, Zhong-Xue Fu, Shou–Ru Zhang, Jin-Bao Guo, Rong Wang, Zhen-Bing Lv & Yong-Fu Xiong. (2017) Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer. Oncotarget 8:30, pages 49318-49328.
Crossref
Crossref
Feng Wang, Xianfei Ding, Tao Wang, Zhengzheng Shan, Jun Wang, Shaoxuan Wu, Yanyan Chi, Yana Zhang, Zhuan Lv, Liuxing Wang & Qingxia Fan. (2017) Metformin inhibited esophageal squamous cell carcinoma proliferation in vitro and in vivo and enhanced the anti-cancer effect of cisplatin. PLOS ONE 12:4, pages e0174276.
Crossref
Crossref
Mo-Han Zhang, Jing-Zhi Jiang, Ying-Lan Cai, Li-Hua Piao & Zheng Jin. (2017) Significance of dynamic changes in gastric smooth muscle cell apoptosis, PI3K-AKT-mTOR and AMPK-mTOR signaling in a rat model of diabetic gastroparesis. Molecular Medicine Reports 16:2, pages 1530-1536.
Crossref
Crossref
Shan Zhuang, Yong-Mei Jian & Yong-Ning Sun. (2017) Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice. World Journal of Gastroenterology 23:23, pages 4233.
Crossref
Crossref
Eun Ho Kim, Mi-Sook Kim, Yoshiya Furusawa, Akiko Uzawa, Soorim Han, Won-Gyun Jung & Sei Sai. (2016) Metformin enhances the radiosensitivity of human liver cancer cells to γ–rays and carbon ion beams. Oncotarget 7:49.
Crossref
Crossref
Nicole M. A. White-Al Habeeb, Julia Garcia, Neil Fleshner & Bharati Bapat. (2016) Metformin Elicits Antitumor Effects and Downregulates the Histone Methyltransferase Multiple Myeloma SET Domain (MMSET) in Prostate Cancer Cells. The Prostate 76:16, pages 1507-1518.
Crossref
Crossref
Keyan Cheng & Min Hao. (2016) Metformin Inhibits TGF-β1-Induced Epithelial-to-Mesenchymal Transition via PKM2 Relative-mTOR/p70s6k Signaling Pathway in Cervical Carcinoma Cells. International Journal of Molecular Sciences 17:12, pages 2000.
Crossref
Crossref
Hyung Sik Kim, Sam Kacew & Byung Mu Lee. (2016) Genetic and epigenetic cancer chemoprevention on molecular targets during multistage carcinogenesis. Archives of Toxicology 90:10, pages 2389-2404.
Crossref
Crossref
Changqing Su. (2016) Survivin in survival of hepatocellular carcinoma. Cancer Letters 379:2, pages 184-190.
Crossref
Crossref
Chin-Hsiao Tseng. (2016) Metformin reduces gastric cancer risk in patients with type 2 diabetes mellitus. Aging 8:8, pages 1636-1649.
Crossref
Crossref
Kyung-Min Lee, Minju Lee, Jiwoo Lee, Sung Wuk Kim, Hyeong-Gon Moon, Dong-Young Noh & Wonshik Han. (2016) Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer. Oncotarget 7:25, pages 38500-38512.
Crossref
Crossref
Anna Dmoszyńska, Monika Podhorecka & Krzysztof Giannopoulos. (2016) Metformina: stary lek w nowej aplikacji. Acta Haematologica Polonica 47:2, pages 139-145.
Crossref
Crossref
Xinke Zhou, Jitao Chen, Gao Yi, Min Deng, Hao Liu, Min Liang, Boyun Shi, Xin Fu, Yuqin Chen, Liangcai Chen, Zhimin He, Jian Wang & Jifang Liu. (2015) Metformin suppresses hypoxia-induced stabilization of HIF-1α through reprogramming of oxygen metabolism in hepatocellular carcinoma. Oncotarget 7:1, pages 873-884.
Crossref
Crossref
Min Sha, Jun Ye, Zheng-yun Luan, Ting Guo, Bian Wang & Jun-xing Huang. (2015) Celastrol induces cell cycle arrest by MicroRNA-21-mTOR-mediated inhibition p27 protein degradation in gastric cancer. Cancer Cell International 15:1.
Crossref
Crossref
Xu Chen, Chuanzhen Hu, Weibin Zhang, Yuhui Shen, Jun Wang, Fangqiong Hu & Pei Yu. (2015) Metformin inhibits the proliferation, metastasis, and cancer stem-like sphere formation in osteosarcoma MG63 cells in vitro. Tumor Biology 36:12, pages 9873-9883.
Crossref
Crossref
Xinbing Sui, Yinghua Xu, Xian Wang, Weidong Han, Hongming Pan & Mang Xiao. (2015) Metformin: A Novel but Controversial Drug in Cancer Prevention and Treatment. Molecular Pharmaceutics 12:11, pages 3783-3791.
Crossref
Crossref
J.A. Jara & R. López-Muñoz. (2015) Metformin and cancer: Between the bioenergetic disturbances and the antifolate activity. Pharmacological Research 101, pages 102-108.
Crossref
Crossref
Xinqun Chai, Hongpeng Chu, Xuan Yang, Yuanpu Meng, Pengfei Shi & Shanmiao Gou. (2015) Metformin Increases Sensitivity of Pancreatic Cancer Cells to Gemcitabine by Reducing CD133+ Cell Populations and Suppressing ERK/P70S6K Signaling. Scientific Reports 5:1.
Crossref
Crossref