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Research Papers

Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells

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Pages 233-243 | Received 22 Sep 2014, Accepted 09 Nov 2014, Published online: 10 Mar 2015

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Hui Guo, Shan Kuang, Qiao-ling Song, Man Liu, Xiao-xiao Sun & Qiang Yu. (2017) Cucurbitacin I inhibits STAT3, but enhances STAT1 signaling in human cancer cells in vitro through disrupting actin filaments. Acta Pharmacologica Sinica 39:3, pages 425-437.
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Xueqiang Zhu, Hui Huang, Jun Zhang, Hao Liu, Rui Ao, Ming Xiao & Yuelei Wu. (2017) The anticancer effects of Cucurbitacin I inhibited cell growth of human non‑small cell lung cancer through PI3K/AKT/p70S6K pathway. Molecular Medicine Reports.
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Anqun Tang, Keyu Gao, Laili Chu, Rui Zhang, Jing Yang & Junnian Zheng. (2017) Aurora kinases: novel therapy targets in cancers. Oncotarget 8:14, pages 23937-23954.
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Shenlu Qin, Xumeng Wang, Huanwen Wu, Peng Xiao, Hongqiang Cheng, Xue Zhang & Yuehai Ke. (2016) Cell-based phenotypic screening of mast cell degranulation unveils kinetic perturbations of agents targeting phosphorylation. Scientific Reports 6:1.
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E. P. Jane, D. R. Premkumar, J. M. Cavaleri, P. A. Sutera, T. Rajasekar & I. F. Pollack. (2015) Dinaciclib, a Cyclin-Dependent Kinase Inhibitor Promotes Proteasomal Degradation of Mcl-1 and Enhances ABT-737-Mediated Cell Death in Malignant Human Glioma Cell Lines. Journal of Pharmacology and Experimental Therapeutics 356:2, pages 354-365.
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Omar Nunez Lopez, Fredrick J. Bohanon, Xiaofu Wang, Na Ye, Tiziana Corsello, Yesenia Rojas-Khalil, Haijun Chen, Haiying Chen, Jia Zhou & Ravi S. Radhakrishnan. (2016) STAT3 inhibition suppresses hepatic stellate cell fibrogenesis: HJC0123, a potential therapeutic agent for liver fibrosis. RSC Advances 6:102, pages 100652-100663.
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