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Virulence Volume 6, 2015 - Issue 2
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Research Paper

Synthetic Scrapie Infectivity: Interaction between Recombinant PrP and Scrapie Brain-Derived RNA

Steve SimoneauDivision of Prions and Related Diseases (SEPIA); Institute of Emerging Diseases and Innovative Therapies (iMETI); CEA; Fontenay-aux-Roses, France;Current affiliation: Department of Biological Safety Surveillance; LFB Biomédicaments; Les Ulis, FrancCorrespondence[email protected] [email protected]
,
Achim ThomzigRobert Koch-Institut; ZBS 6 - Proteomics and Spectroscopy, Prions and Prionoids Research Unit; Robert Koch-Institut; Berlin, Germany
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Marie-Madeleine RuchouxDivision of Prions and Related Diseases (SEPIA); Institute of Emerging Diseases and Innovative Therapies (iMETI); CEA; Fontenay-aux-Roses, France
,
Nicolas VignierU974 INSERM, UMRS 7215 CNRS; Institut de Myologie, Hôpital Pitié-Salpêtrière; Paris, France
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Martin L DausRobert Koch-Institut; ZBS 6 - Proteomics and Spectroscopy, Prions and Prionoids Research Unit; Robert Koch-Institut; Berlin, Germany
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Anna PoleggiDepartment of Cell Biology and Neurosciences; Istituto Superiore di Sanità; Roma, Italy
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Pierre LebonLaboratoire de Virologie; Hôpital Cochin-Saint Vincent de Paul, Assistance-Publique-Hôpitaux de Paris; Paris, France
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Sophie FreireDivision of Prions and Related Diseases (SEPIA); Institute of Emerging Diseases and Innovative Therapies (iMETI); CEA; Fontenay-aux-Roses, France
,
Valerie DurandDivision of Prions and Related Diseases (SEPIA); Institute of Emerging Diseases and Innovative Therapies (iMETI); CEA; Fontenay-aux-Roses, France
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Silvia GrazianoDepartment of Cell Biology and Neurosciences; Istituto Superiore di Sanità; Roma, Italy
,
Roberta GalenoDepartment of Cell Biology and Neurosciences; Istituto Superiore di Sanità; Roma, Italy
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Franco CardoneDepartment of Cell Biology and Neurosciences; Istituto Superiore di Sanità; Roma, Italy
,
Emmanuel ComoyDivision of Prions and Related Diseases (SEPIA); Institute of Emerging Diseases and Innovative Therapies (iMETI); CEA; Fontenay-aux-Roses, France
,
Maurizio PocchiariDepartment of Cell Biology and Neurosciences; Istituto Superiore di Sanità; Roma, Italy
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Michael BeekesRobert Koch-Institut; ZBS 6 - Proteomics and Spectroscopy, Prions and Prionoids Research Unit; Robert Koch-Institut; Berlin, Germany
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Jean-Philippe DeslysDivision of Prions and Related Diseases (SEPIA); Institute of Emerging Diseases and Innovative Therapies (iMETI); CEA; Fontenay-aux-Roses, France
&
Jean-Guy FournierDivision of Prions and Related Diseases (SEPIA); Institute of Emerging Diseases and Innovative Therapies (iMETI); CEA; Fontenay-aux-Roses, FranceCorrespondence[email protected] [email protected]
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Pages 132-144 | Received 13 May 2014, Accepted 17 Nov 2014, Published online: 16 Mar 2015

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Sotirios Botsios, Sarah Tittman & Laura Manuelidis. (2015) Rapid chemical decontamination of infectious CJD and scrapie particles parallels treatments known to disrupt microbes and biofilms. Virulence 6:8, pages 787-801.
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Articles from other publishers (10)

Jan P. M. Langeveld, Anne Balkema-Buschmann, Dieter Becher, Achim Thomzig, Romolo Nonno, Olivier Andréoletti, Aart Davidse, Michele A. Di Bari, Laura Pirisinu, Umberto Agrimi, Martin H. Groschup, Michael Beekes & Jason Shih. (2021) Stability of BSE infectivity towards heat treatment even after proteolytic removal of prion protein. Veterinary Research 52:1.
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Mariana J. do Amaral & Yraima Cordeiro. 2021. Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C. Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C 1 43 .
Richard Lathe & Jean-Luc Darlix. (2020) Prion protein PrP nucleic acid binding and mobilization implicates retroelements as the replicative component of transmissible spongiform encephalopathy. Archives of Virology 165:3, pages 535-556.
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Petar Stefanov Kovachev, Mariana P. B. Gomes, Yraima Cordeiro, Natália C. Ferreira, Leticia P. Felix Valadão, Lucas M. Ascari, Luciana P. Rangel, Jerson L. Silva & Suparna Sanyal. (2019) RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction. Scientific Reports 9:1.
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R. N. Mustafin & E. K. Khusnutdinova. (2018) INTERRELATION OF PRIONS WITH NON-CODING RNAS. Vavilov Journal of Genetics and Breeding 22:4, pages 415-424.
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Bruno Macedo & Yraima Cordeiro. (2017) Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids. International Journal of Molecular Sciences 18:5, pages 1023.
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Rona M. Barron, Declan King, Martin Jeffrey, Gillian McGovern, Sonya Agarwal, Andrew C. Gill & Pedro Piccardo. (2016) PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions. Acta Neuropathologica 132:4, pages 611-624.
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Jerson L. Silva & Yraima Cordeiro. (2016) The “Jekyll and Hyde” Actions of Nucleic Acids on the Prion-like Aggregation of Proteins. Journal of Biological Chemistry 291:30, pages 15482-15490.
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Martin Daus. (2016) Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma. Biology 5:1, pages 2.
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Martin L Daus. (2015) Techniques to elucidate the conformation of prions. World Journal of Biological Chemistry 6:3, pages 218.
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