Advanced search
Publication Cover
Autophagy Volume 9, 2013 - Issue 1
Submit an article Journal homepage
1,326
Views
40
CrossRef citations to date
0
Altmetric
Autophagic Punctum

Reactivation of autophagy ameliorates LMNA cardiomyopathy

Jason C. Choi Department of Medicine and Department of Pathology and Cell Biology; College of Physicians and Surgeons; Columbia University; New York, NY USA
&
Howard J. Worman Department of Medicine and Department of Pathology and Cell Biology; College of Physicians and Surgeons; Columbia University; New York, NY USACorrespondence[email protected]
Pages 110-111 | Received 13 Sep 2012, Accepted 28 Sep 2012, Published online: 08 Oct 2012

Citations (40)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Deling Jiao, Zhen Yang, Lulu Wang, Binyue Hu, Jing Wang, Anyong Xu, Wenmin Cheng, Baoyu Jia, Yubo Qing, Hong-Ye Zhao & Hong-Jiang Wei. (2019) Endogenous leptin promotes autophagy in EBSS-induced PFCs. Animal Cells and Systems 23:5, pages 318-325.
Read now
Stephanie J. Davies, James Ryan, Patrick B. F. O'Connor, Elaine Kenny, Derek Morris, Pavel V. Baranov, Rosemary O'Connor & Tommie V. McCarthy. (2017) Itm2a silencing rescues lamin A mediated inhibition of 3T3-L1 adipocyte differentiation. Adipocyte 6:4, pages 259-276.
Read now
Wanyun Zhu, Hao Qu, Kaixiang Xu, Baoyu Jia, Haifeng Li, Yimin Du, Guangming Liu, Hong-Jiang Wei & Hong-Ye Zhao. (2017) Differences in the starvation-induced autophagy response in MDA-MB-231 and MCF-7 breast cancer cells. Animal Cells and Systems 21:3, pages 190-198.
Read now
Giovanna Lattanzi, Sara Benedetti, Maria Rosaria D’Apice, Lorenzo Maggi, Nicola Carboni, Emanuela Scarano & Luisa Politano. (2016) Emerging perspectives on laminopathies. Cell Health and Cytoskeleton 8, pages 25-35.
Read now
Eivind Lund & Philippe Collas. (2013) Nuclear lamins. Nucleus 4:6, pages 424-430.
Read now

Articles from other publishers (35)

Fatima D. Elzamzami, Arushi Samal, Adith S. Arun, Tejas Dharmaraj, Neeti R. Prasad, Alex Rendon-Jonguitud, Lauren DeVine, Jeremy D. Walston, Robert N. Cole & Katherine L. Wilson. (2023) Native lamin A/C proteomes and novel partners from heart and skeletal muscle in a mouse chronic inflammation model of human frailty. Frontiers in Cell and Developmental Biology 11.
Crossref
Sophie L.V.M. Stroeks, Ida G. Lunde, Debby M.E.I. HellebrekersGodelieve R.F. Claes, Hiroko Wakimoto, Joshua Gorham, Ingrid P.C. Krapels, Els K. Vanhoutte, Arthur van den WijngaardMichiel T.H.M. Henkens, Anne G. Raafs, Maurits A. SikkingJos L.V. BroersMiranda NabbenElizabeth A.V. Jones, Stephane R.B. Heymans, Han G. Brunner & Job A.J. Verdonschot. (2023) Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy. Circulation: Genomic and Precision Medicine 16:2.
Crossref
Olesya Golubeva, Alina Pogorelova & Viktor Ilchenko. 2023. Networked Control Systems for Connected and Automated Vehicles. Networked Control Systems for Connected and Automated Vehicles 1353 1362 .
Xiaoyue Wen, Bing Xie, Shiying Yuan & Jiancheng Zhang. (2022) The “Self-Sacrifice” of ImmuneCells in Sepsis. Frontiers in Immunology 13.
Crossref
Jiajia Yang, Mariana A. Argenziano, Mariana Burgos Angulo, Alexander Bertalovitz, Maliheh Najari Beidokhti & Thomas V. McDonald. (2021) Phenotypic Variability in iPSC-Induced Cardiomyocytes and Cardiac Fibroblasts Carrying Diverse LMNA Mutations. Frontiers in Physiology 12.
Crossref
Karl P. Schlingmann, François Jouret, Kuang Shen, Anukrati Nigam, Francisco J. Arjona, Claudia Dafinger, Pascal Houillier, Deborah P. Jones, Felix Kleinerüschkamp, Jun Oh, Nathalie Godefroid, Mehmet Eltan, Tülay Güran, Stéphane Burtey, Marie-Christine Parotte, Jens König, Alina Braun, Caro Bos, Maria Ibars Serra, Holger Rehmann, Fried J.T. Zwartkruis, Kirsten Y. Renkema, Karin Klingel, Eric Schulze-Bahr, Bernhard Schermer, Carsten Bergmann, Janine Altmüller, Holger Thiele, Bodo B. Beck, Karin Dahan, David Sabatini, Max C. Liebau, Rosa Vargas-Poussou, Nine V.A.M. Knoers, Martin Konrad & Jeroen H.F. de Baaij. (2021) mTOR-Activating Mutations in RRAGD Are Causative for Kidney Tubulopathy and Cardiomyopathy. Journal of the American Society of Nephrology 32:11, pages 2885-2899.
Crossref
Hai-Peng Li, Ji-Ting Liu, Yuan-Xiu Chen, Wen-Bin Wang, Yue Han, Qing-Ping Yao & Ying-Xin Qi. (2021) Suppressed nuclear envelope proteins activate autophagy of vascular smooth muscle cells during cyclic stretch application. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868:1, pages 118855.
Crossref
Milton Packer. (2020) Longevity genes, cardiac ageing, and the pathogenesis of cardiomyopathy: implications for understanding the effects of current and future treatments for heart failure. European Heart Journal 41:39, pages 3856-3861.
Crossref
Milton Packer. (2020) Molecular, Cellular, and Clinical Evidence That Sodium‐Glucose Cotransporter 2 Inhibitors Act as Neurohormonal Antagonists When Used for the Treatment of Chronic Heart Failure. Journal of the American Heart Association 9:16.
Crossref
Yuan Gao, Zhonglin Han, Xiang Wu, Rongfang Lan, Xinlin Zhang, Wenzhi Shen, Yu Liu, Xuehua Liu, Xi Lan, Biao Xu & Wei Xu. (2020) Next-generation sequencing identifies a novel heterozygous I229T mutation on LMNA associated with familial cardiac conduction disease. Medicine 99:34, pages e21797.
Crossref
Yuxin Zheng, Lizhu Ma, Ning Liu, Xiaorong Tang, Shun Guo, Bin Zhang & Zhongliang Jiang. (2019) Autophagy and Apoptosis of Porcine Ovarian Granulosa Cells During Follicular Development. Animals 9:12, pages 1111.
Crossref
Rachel M. Stewart, Elisa C. Rodriguez & Megan C. King. (2019) Ablation of SUN2-containing LINC complexes drives cardiac hypertrophy without interstitial fibrosis. Molecular Biology of the Cell 30:14, pages 1664-1675.
Crossref
Francesca Chiarini, Camilla Evangelisti, Vittoria Cenni, Antonietta Fazio, Francesca Paganelli, Alberto Martelli & Giovanna Lattanzi. (2019) The Cutting Edge: The Role of mTOR Signaling in Laminopathies. International Journal of Molecular Sciences 20:4, pages 847.
Crossref
Dan Simon, Amanda Wriston, Qiong Fan, Jeffrey Shabanowitz, Alyssa Florwick, Tejas Dharmaraj, Sherket Peterson, Yosef Gruenbaum, Cathrine Carlson, Line Grønning-Wang, Donald Hunt & Katherine Wilson. (2018) OGT (O-GlcNAc Transferase) Selectively Modifies Multiple Residues Unique to Lamin A. Cells 7:5, pages 44.
Crossref
Graham F. Brady, Raymond Kwan, Juliana Bragazzi Cunha, Jared S. Elenbaas & M. Bishr Omary. (2018) Lamins and Lamin-Associated Proteins in Gastrointestinal Health and Disease. Gastroenterology 154:6, pages 1602-1619.e1.
Crossref
Amanda J. DuBoseStephen T. LichtensteinNoreen M. PetrashMichael R. ErdosLeslie B. Gordon & Francis S. Collins. (2018) Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts. Proceedings of the National Academy of Sciences 115:16, pages 4206-4211.
Crossref
Kim Goodsell. (2018) Gaming Aging in the “Omic” Era. Circulation Research 122:5, pages 646-648.
Crossref
Gabriella Captur, Eloisa Arbustini, Gisèle Bonne, Petros Syrris, Kevin Mills, Karim Wahbi, Saidi A Mohiddin, William J McKenna, Stephen Pettit, Carolyn Y Ho, Antoine Muchir, Paul Gissen, Perry M Elliott & James C Moon. (2018) Lamin and the heart. Heart 104:6, pages 468-479.
Crossref
Rachel M. Stewart, Megan C. King & Valerie Horsley. 2018. Epigenetic Regulation of Skin Development and Regeneration. Epigenetic Regulation of Skin Development and Regeneration 263 292 .
Yee-Ki Lee, Yu Jiang, Xin-Ru Ran, Yee-Man Lau, Kwong-Man Ng, Wing-Hon Kevin Lai, Chung-Wah Siu & Hung-Fat Tse. (2016) Recent advances in animal and human pluripotent stem cell modeling of cardiac laminopathy. Stem Cell Research & Therapy 7:1.
Crossref
Peter Meinke & Eric C. Schirmer. (2016) The increasing relevance of nuclear envelope myopathies. Current Opinion in Neurology 29:5, pages 651-661.
Crossref
Lorenzo Maggi, Nicola Carboni & Pia Bernasconi. (2016) Skeletal Muscle Laminopathies: A Review of Clinical and Molecular Features. Cells 5:3, pages 33.
Crossref
Joseph R Tran, Haiyang Chen, Xiaobin Zheng & Yixian Zheng. (2016) Lamin in inflammation and aging. Current Opinion in Cell Biology 40, pages 124-130.
Crossref
Gun West, Josef Gullmets, Laura Virtanen, Song Ping Li, Anni Keinänen, Takeshi Shimi, Monika Mauermann, Tiina Heliö, Maija Kaartinen, Laura Ollila, Johanna Kuusisto, John E. Eriksson, Robert D. Goldman, Harald Herrmann & Pekka Taimen. (2016) Deleterious assembly of mutant p.S143P lamin A/C causes ER stress in familial dilated cardiomyopathy. Journal of Cell Science.
Crossref
Brant M. Webster & C. Patrick Lusk. (2016) Border Safety: Quality Control at the Nuclear Envelope. Trends in Cell Biology 26:1, pages 29-39.
Crossref
Trisha J. Grevengoed, Daniel E. Cooper, Pamela A. Young, Jessica M. Ellis & Rosalind A. Coleman. (2015) Loss of long‐chain acyl‐CoA synthetase isoform 1 impairs cardiac autophagy and mitochondrial structure through mechanistic target of rapamycin complex 1 activation. The FASEB Journal 29:11, pages 4641-4653.
Crossref
Jun Ren & Heinrich Taegtmeyer. (2015) Too much or not enough of a good thing — The Janus faces of autophagy in cardiac fuel and protein homeostasis. Journal of Molecular and Cellular Cardiology 84, pages 223-226.
Crossref
Yosef GruenbaumRoland Foisner. (2015) Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation. Annual Review of Biochemistry 84:1, pages 131-164.
Crossref
Yu Mei, Melissa D. Thompson, Richard A. Cohen & XiaoYong Tong. (2015) Autophagy and oxidative stress in cardiovascular diseases. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1852:2, pages 243-251.
Crossref
Lei Song, Ming Su, Shuiyun Wang, Yubao Zou, Xiaojian Wang, Yilu Wang, Hongli Cui, Peng Zhao, Rutai Hui & Jizheng Wang. (2014) MiR‐451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC 1 . Journal of Cellular and Molecular Medicine 18:11, pages 2266-2274.
Crossref
Xihui XuNathan D. RoeMary C.M. Weiser-EvansJun Ren. (2014) Inhibition of Mammalian Target of Rapamycin With Rapamycin Reverses Hypertrophic Cardiomyopathy in Mice With Cardiomyocyte-Specific Knockout of PTEN. Hypertension 63:4, pages 729-739.
Crossref
Philippe Collas, Eivind G. Lund & Anja R. Oldenburg. (2014) Closing the (nuclear) envelope on the genome: How nuclear lamins interact with promoters and modulate gene expression. BioEssays 36:1, pages 75-83.
Crossref
Marco Sandri, Luisa Coletto, Paolo Grumati & Paolo Bonaldo. (2013) Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies. Journal of Cell Science 126:23, pages 5325-5333.
Crossref
Yanushi Dullewe Wijeyeratne & Elijah R. Behr. (2013) Recent Developments in the Genetics of Cardiomyopathies. Current Genetic Medicine Reports 1:1, pages 21-29.
Crossref
Matt Kaeberlein. (2013) mTOR Inhibition: From Aging to Autism and Beyond. Scientifica 2013, pages 1-17.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.