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Basic Research Paper

Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2

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Pages 361-373 | Received 27 Apr 2012, Accepted 30 Nov 2012, Published online: 04 Jan 2013

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Crossref
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Crossref
Shigeru Shibata, Kenichi Ishizawa, Qin Wang, Ning Xu, Toshiro Fujita, Shunya Uchida & Richard P. Lifton. (2018) ULK1 Phosphorylates and Regulates Mineralocorticoid Receptor. Cell Reports 24:3, pages 569-576.
Crossref
Claudia ManzoniAdamantios MamaisSybille DihanichMarc P.M. SoutarHelene Plun-FavreauRina BandopadhyayRosella AbetiPaola GiuntiJohn HardyMark R. CooksonSharon A. ToozePatrick A. Lewis. (2018) mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Bioscience Reports 38:2.
Crossref
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Crossref
Björn Stork. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 5831 5844 .
Laura E Gallagher, Ohood A Radhi, Mahmud O Abdullah, Anthony G McCluskey, Marie Boyd & Edmond Y W Chan. (2017) Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Cell Death & Disease 8:8, pages e3014-e3014.
Crossref
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Crossref
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Crossref
Daniela Bakula, Amelie J. Müller, Theresia Zuleger, Zsuzsanna Takacs, Mirita Franz-Wachtel, Ann-Katrin Thost, Daniel Brigger, Mario P. Tschan, Tancred Frickey, Horst Robenek, Boris Macek & Tassula Proikas-Cezanne. (2017) WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nature Communications 8:1.
Crossref
Fangfang Jin, Yanbo Wang, Mingzhen Li, Yanan Zhu, Hongwei Liang, Chen Wang, Feng Wang, Chen-Yu Zhang, Ke Zen & Limin Li. (2017) MiR-26 enhances chemosensitivity and promotes apoptosis of hepatocellular carcinoma cells through inhibiting autophagy. Cell Death & Disease 8:1, pages e2540-e2540.
Crossref
Daniel Prantner, Darren J. Perkins & Stefanie N. Vogel. (2017) AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling. Journal of Biological Chemistry 292:1, pages 292-304.
Crossref
M. Vicinanza, M.J. Gratian, M. Bowen & D.C. Rubinsztein. 2017. Molecular Characterization of Autophagic Responses, Part A. Molecular Characterization of Autophagic Responses, Part A 311 330 .
N. Dupont, A.C. Nascimbeni, E. Morel & P. Codogno. 2017. 1 23 .
Olivia C. McKee-Muir & Ryan C. Russell. 2017. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging 231 250 .
Xiao Liu, Haihong Qin & Jinhua Xu. (2016) The role of autophagy in the pathogenesis of systemic lupus erythematosus. International Immunopharmacology 40, pages 351-361.
Crossref
Claudia Manzoni, Adamantios Mamais, Dorien A. Roosen, Sybille Dihanich, Marc P. M. Soutar, Helene Plun-Favreau, Rina Bandopadhyay, John Hardy, Sharon A. Tooze, Mark R. Cookson & Patrick A. Lewis. (2016) mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1. Scientific Reports 6:1.
Crossref
Kay O. Schink, Kia-Wee Tan & Harald Stenmark. (2016) Phosphoinositides in Control of Membrane Dynamics. Annual Review of Cell and Developmental Biology 32:1, pages 143-171.
Crossref
Elizabeth Liu, Yalitza Lopez Corcino, Jose-Andres C. Portillo, Yanling Miao & Carlos S. Subauste. (2016) Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages. Infection and Immunity 84:9, pages 2616-2626.
Crossref
Nicholas T. Ktistakis & Sharon A. Tooze. (2016) Digesting the Expanding Mechanisms of Autophagy. Trends in Cell Biology 26:8, pages 624-635.
Crossref
Mehri Igci, Mehmet Baysan, Remzi Yigiter, Mustafa Ulasli, Sirma Geyik, Recep Bayraktar, İbrahim Bozgeyik, Esra Bozgeyik, Ali Bayram & Ecir Ali Cakmak. (2016) Gene expression profiles of autophagy-related genes in multiple sclerosis. Gene 588:1, pages 38-46.
Crossref
Alf Håkon Lystad & Anne Simonsen. (2016) Phosphoinositide-binding proteins in autophagy. FEBS Letters 590:15, pages 2454-2468.
Crossref
Carla F. BentoMaurizio RennaGhita GhislatClaudia PuriAvraham AshkenaziMariella VicinanzaFiona M. MenziesDavid C. Rubinsztein. (2016) Mammalian Autophagy: How Does It Work?. Annual Review of Biochemistry 85:1, pages 685-713.
Crossref
Laura Gallagher, Leon Williamson & Edmond Chan. (2016) Advances in Autophagy Regulatory Mechanisms. Cells 5:2, pages 24.
Crossref
Mary G Lin & James H Hurley. (2016) Structure and function of the ULK1 complex in autophagy. Current Opinion in Cell Biology 39, pages 61-68.
Crossref
P Fortini, C Ferretti, E Iorio, M Cagnin, L Garribba, D Pietraforte, M Falchi, B Pascucci, S Baccarini, F Morani, S Phadngam, G De Luca, C Isidoro & E Dogliotti. (2016) The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis. Cell Death & Disease 7:3, pages e2168-e2168.
Crossref
Panagiotis Giannogonas, Athanasia Apostolou, Antigoni Manousopoulou, Stamatis Theocharis, Sofia A. Macari, Stelios Psarras, Spiros D. Garbis, Charalabos Pothoulakis & Katia P. Karalis. (2016) Identification of a novel interaction between corticotropin releasing hormone (Crh) and macroautophagy. Scientific Reports 6:1.
Crossref
Benoit Pasquier. (2015) Autophagy inhibitors. Cellular and Molecular Life Sciences 73:5, pages 985-1001.
Crossref
Björn Stork. 2017. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 1 15 .
Jacqueline M. Kimmey, Jeremy P. Huynh, Leslie A. Weiss, Sunmin Park, Amal Kambal, Jayanta Debnath, Herbert W. Virgin & Christina L. Stallings. (2015) Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection. Nature 528:7583, pages 565-569.
Crossref
Sebastian Wesselborg & Björn Stork. (2015) Autophagy signal transduction by ATG proteins: from hierarchies to networks. Cellular and Molecular Life Sciences 72:24, pages 4721-4757.
Crossref
Alfred J. Meijer, Séverine Lorin, Edward F. Blommaart & Patrice Codogno. (2014) Regulation of autophagy by amino acids and MTOR-dependent signal transduction. Amino Acids 47:10, pages 2037-2063.
Crossref
Nobuo N. Noda & Yuko Fujioka. (2015) Atg1 family kinases in autophagy initiation. Cellular and Molecular Life Sciences 72:16, pages 3083-3096.
Crossref
Sung Hwa Shin, Eun Jeoung Lee, Jaesun Chun, Sunghee Hyun & Sang Sun Kang. (2015) ULK2 Ser 1027 Phosphorylation by PKA Regulates Its Nuclear Localization Occurring through Karyopherin Beta 2 Recognition of a PY-NLS Motif. PLOS ONE 10:6, pages e0127784.
Crossref
Jordan WengrodDing WangSarah WeissHua ZhongIman OsmanLawrence B. Gardner. (2015) Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Science Signaling 8:367.
Crossref
Ann-Katrin Thost, Pierre Dönnes, Oliver Kohlbacher & Tassula Proikas-Cezanne. (2015) Fluorescence-based imaging of autophagy progression by human WIPI protein detection. Methods 75, pages 69-78.
Crossref
Quanquan Sun, Tongxin Liu, Yawei Yuan, Zhenli Guo, Guozhu Xie, Shasha Du, Xiaoshan Lin, Zhixin Xu, Minfeng Liu, Wei Wang, Quan Yuan & Longhua Chen. (2015) MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1. International Journal of Cancer 136:5, pages 1003-1012.
Crossref
Qijun Zheng, Kun Zhao, Xuefeng Han, Anna F. Huff, Qin Cui, Sara A. Babcock, Shiqiang Yu & Yingmei Zhang. (2015) Inhibition of AMPK accentuates prolonged caloric restriction-induced change in cardiac contractile function through disruption of compensatory autophagy. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1852:2, pages 332-342.
Crossref
Tassula Proikas-Cezanne, Zsuzsanna Takacs, Pierre Dönnes & Oliver Kohlbacher. (2015) WIPI proteins: essential PtdIns3 P effectors at the nascent autophagosome . Journal of Cell Science.
Crossref
Mariella Vicinanza, Viktor I. Korolchuk, Avraham Ashkenazi, Claudia Puri, Fiona M. Menzies, Jonathan H. Clarke & David C. Rubinsztein. (2015) PI(5)P Regulates Autophagosome Biogenesis. Molecular Cell 57:2, pages 219-234.
Crossref
Junhui Xing, Hongtao Liu, Huabing Yang, Rui Chen, Yuguo Chen & Jian Xu. (2014) Upregulation of Unc-51-Like Kinase 1 by Nitric Oxide Stabilizes SIRT1, Independent of Autophagy. PLoS ONE 9:12, pages e116165.
Crossref
Seung-Hyun Ro, Ian A. Semple, Haewon Park, Haeli Park, Hwan-Woo Park, Myungjin Kim, Jeong Sig Kim & Jun Hee Lee. (2014) Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1. FEBS Journal 281:17, pages 3816-3827.
Crossref
Jayoung Choi, Sunmin Park, Scott B. Biering, Elizabeth Selleck, Catherine Y. Liu, Xin Zhang, Naonobu Fujita, Tatsuya Saitoh, Shizuo Akira, Tamotsu Yoshimori, L. David Sibley, Seungmin Hwang & Herbert W. Virgin. (2014) The Parasitophorous Vacuole Membrane of Toxoplasma gondii Is Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy. Immunity 40:6, pages 924-935.
Crossref
Fengying Yang, Xiaolei Chu, Miaomiao Yin, Xiaolei Liu, Hairui Yuan, Yanmei Niu & Li Fu. (2014) mTOR and autophagy in normal brain aging and caloric restriction ameliorating age-related cognition deficits. Behavioural Brain Research 264, pages 82-90.
Crossref
Wenxian Wu, Weili Tian, Zhe Hu, Guo Chen, Lei Huang, Wen Li, Xingli Zhang, Peng Xue, Changqian Zhou, Lei Liu, Yushan Zhu, Xingliang Zhang, Longxuan Li, Liangqing Zhang, Senfang Sui, Bin Zhao & Du Feng. (2014) ULK 1 translocates to mitochondria and phosphorylates FUNDC 1 to regulate mitophagy . EMBO reports 15:5, pages 566-575.
Crossref
Benjamin S. Padman, Markus Bach & Georg Ramm. (2014) An Improved Procedure for Subcellular Spatial Alignment during Live-Cell CLEM. PLoS ONE 9:4, pages e95967.
Crossref
Aditya Murthy, Yun Li, Ivan Peng, Mike Reichelt, Anand Kumar Katakam, Rajkumar Noubade, Merone Roose-Girma, Jason DeVoss, Lauri Diehl, Robert R. Graham & Menno van Lookeren Campagne. (2014) A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3. Nature 506:7489, pages 456-462.
Crossref
Rossella Titone, Federica Morani, Carlo Follo, Chiara Vidoni, Delia Mezzanzanica & Ciro Isidoro. (2014) Epigenetic Control of Autophagy by MicroRNAs in Ovarian Cancer. BioMed Research International 2014, pages 1-11.
Crossref
Ryan C Russell, Hai-Xin Yuan & Kun-Liang Guan. (2013) Autophagy regulation by nutrient signaling. Cell Research 24:1, pages 42-57.
Crossref
Robin E. Stanley, Michael J. Ragusa & James H. Hurley. (2014) The beginning of the end: how scaffolds nucleate autophagosome biogenesis. Trends in Cell Biology 24:1, pages 73-81.
Crossref
Christopher A. Lamb, Tamotsu Yoshimori & Sharon A. Tooze. (2013) The autophagosome: origins unknown, biogenesis complex. Nature Reviews Molecular Cell Biology 14:12, pages 759-774.
Crossref
Nicolas Dupont & Patrice Codogno. (2013) Non-canonical Autophagy: Facts and Prospects. Current Pathobiology Reports 1:4, pages 263-271.
Crossref
Silvia Ramírez-Peinado, Clara Lucía León-Annicchiarico, Javier Galindo-Moreno, Raffaella Iurlaro, Alfredo Caro-Maldonado, Jochen H.M. Prehn, Kevin M. Ryan & Cristina Muñoz-Pinedo. (2013) Glucose-starved Cells Do Not Engage in Prosurvival Autophagy. Journal of Biological Chemistry 288:42, pages 30387-30398.
Crossref
Rebecca RobertsNicholas T. Ktistakis. (2013) Omegasomes: PI3P platforms that manufacture autophagosomes. Essays in Biochemistry 55, pages 17-27.
Crossref
Laura E. GallagherEdmond Y.W. Chan. (2013) Early signalling events of autophagy. Essays in Biochemistry 55, pages 1-15.
Crossref
Eyal Kalie, Minoo Razi & Sharon A. Tooze. (2013) ULK1 Regulates Melanin Levels in MNT-1 Cells Independently of mTORC1. PLoS ONE 8:9, pages e75313.
Crossref
Yoshinobu Ichimura, Satoshi Waguri, Yu-shin Sou, Shun Kageyama, Jun Hasegawa, Ryosuke Ishimura, Tetsuya Saito, Yinjie Yang, Tsuguka Kouno, Toshiaki Fukutomi, Takayuki Hoshii, Atsushi Hirao, Kenji Takagi, Tsunehiro Mizushima, Hozumi Motohashi, Myung-Shik Lee, Tamotsu Yoshimori, Keiji Tanaka, Masayuki Yamamoto & Masaaki Komatsu. (2013) Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy. Molecular Cell 51:5, pages 618-631.
Crossref
Daniela Bakula, Zsuzsanna Takacs & Tassula Proikas-Cezanne. (2013) WIPI β-propellers in autophagy-related diseases and longevity. Biochemical Society Transactions 41:4, pages 962-967.
Crossref

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