Citations (62)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
Nivedita Hegdekar, Chinmoy Sarkar, Sabrina Bustos, Rodney M. Ritzel, Marie Hanscom, Prarthana Ravishankar, Deepika Philkana, Junfang Wu, David J. Loane & Marta M. Lipinski. (2023) Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes. Autophagy 19:7, pages 2026-2044.
Read now
Read now
Shan-Ying Wu, Hung-Tsung Wu, Yi-Ching Wang, Chih-Jen Chang, Yan-Shen Shan, Shang-Rung Wu, Yen-Chi Chiu, Chia-Lang Hsu, Hsueh-Fen Juan, Kai-Ying Lan, Chi-Wen Chu, Ying-Ray Lee, Sheng-Hui Lan & Hsiao-Sheng Liu. (2023) Secretory autophagy promotes RAB37-mediated insulin secretion under glucose stimulation both in vitro and in vivo. Autophagy 19:4, pages 1239-1257.
Read now
Read now
Vijay Kumar Arruri, Chayanika Gundu, Anil Kumar Kalvala, Bhoomika Sherkhane, Dharmendra Kumar Khatri & Shashi Bala Singh. (2022) Carvacrol abates NLRP3 inflammasome activation by augmenting Keap1/Nrf-2/p62 directed autophagy and mitochondrial quality control in neuropathic pain. Nutritional Neuroscience 25:8, pages 1731-1746.
Read now
Read now
Yujun Xu, Yi Li, Xinghan Liu, Yuchen Pan, Zhiheng Sun, Yaxian Xue, Tingting Wang, Huan Dou & Yayi Hou. (2019) SPIONs enhances IL-10-producing macrophages to relieve sepsis via Cav1-Notch1/HES1-mediated autophagy. International Journal of Nanomedicine 14, pages 6779-6797.
Read now
Read now
Lopa M. Das, Amy M. Binko, Zachary P. Traylor, Han Peng & Kurt Q. Lu. (2019) Vitamin D improves sunburns by increasing autophagy in M2 macrophages. Autophagy 15:5, pages 813-826.
Read now
Read now
Libo Jiang, Fenglai Yuan, Xiaofan Yin & Jian Dong. (2014) Responses and adaptations of intervertebral disc cells to microenvironmental stress: a possible central role of autophagy in the adaptive mechanism. Connective Tissue Research 55:5-6, pages 311-321.
Read now
Read now
Articles from other publishers (56)
Renjie Hu, Huigen Luo, Yuna Ji, Zheng Wang, Pengchao Zheng, Huiya Ouyang, Xinchen Wang, Yun Wang, Baicheng Bao, Guiqing Liao & Baoshan Xu. (2023) Activation of NLRP3 signaling contributes to cadmium-induced bone defects, associated with autophagic flux obstruction. Science of The Total Environment 893, pages 164787.
Crossref
Crossref
Tianming Liu, Qiang Wang, Zhiwei Du, Lu Yin, Jiachen Li, Xianzhi Meng & Dongbo Xue. (2023) The trigger for pancreatic disease: NLRP3 inflammasome. Cell Death Discovery 9:1.
Crossref
Crossref
Emanuella S. A. Sousa, Luiz A. D. Queiroz, João P. T. Guimarães, Kamilla C. Pantoja, Rafael S. Barros, Sabrina Epiphanio & Joilson O. Martins. (2023) The influence of high glucose conditions on macrophages and its effect on the autophagy pathway. Frontiers in Immunology 14.
Crossref
Crossref
Hui Wang, Nivedita Banerjee, Gangduo Wang & M. Firoze Khan. (2023) Autophagy dysregulation in trichloroethene-mediated inflammation and autoimmune response. Toxicology 487, pages 153468.
Crossref
Crossref
Zahra Abedi Kichi, Lucia Natarelli, Saeed Sadeghian, Mohammad ali Boroumand, Mehrdad Behmanesh & Christian Weber. (2022) Orphan GPR26 Counteracts Early Phases of Hyperglycemia-Mediated Monocyte Activation and Is Suppressed in Diabetic Patients. Biomedicines 10:7, pages 1736.
Crossref
Crossref
Jian Zhou, Faxuan Wang, Leina Jia, Ru Chai, Hengquan Wang, Xiaolan Wang, Jiangping Li, Kai Wang, Pengju Zhang & Huifang Yang. (2022)
2,4‐dichlorophenoxyacetic acid induces
ROS
activation in
NLRP3
inflammatory body‐induced autophagy disorder in microglia and the protective effect of
Lycium barbarum
polysaccharide
. Environmental Toxicology 37:5, pages 1136-1151.
Crossref
Crossref
Li-Xiang Wu, Yi-Chuang Xu, Christer Hogstrand, Tao Zhao, Kun Wu, Yi-Huan Xu, Wei Liu & Zhi Luo. (2022) Lipophagy mediated glucose-induced changes of lipid deposition and metabolism via ROS dependent AKT-Beclin1 activation. The Journal of Nutritional Biochemistry 100, pages 108882.
Crossref
Crossref
YanZhi Zhang, Gulimila Aisker, Huaiyang Dong, Gulihaixia Halemahebai, Yan Zhang & Linai Tian. (2021) Urolithin A suppresses glucolipotoxicity-induced ER stress and TXNIP/NLRP3/IL-1β inflammation signal in pancreatic β cells by regulating AMPK and autophagy. Phytomedicine 93, pages 153741.
Crossref
Crossref
Cosimo DE NUNZIO, Simona GIGLIO, Valeria BALDASSARRI, Roberto CIROMBELLA, Giuseppe MALLEL, Antonio NACCHIA, Andrea TUBARO & Andrea VECCHIONE. (2021) Impairment of autophagy may represent the molecular mechanism behind the relationship between obesity and inflammation in patients with BPH and LUTS. Minerva Urology and Nephrology 73:5.
Crossref
Crossref
Ding Yao, Yang GangYi & Wu QiNan. (2021) Autophagic dysfunction of β cell dysfunction in type 2 diabetes, a double-edged sword. Genes & Diseases 8:4, pages 438-447.
Crossref
Crossref
Kang Geng, Xiumei Ma, Zongzhe Jiang, Wei Huang, Chenlin Gao, Yueli Pu, Lifang Luo, Youhua Xu & Yong Xu. (2021) Innate Immunity in Diabetic Wound Healing: Focus on the Mastermind Hidden in Chronic Inflammatory. Frontiers in Pharmacology 12.
Crossref
Crossref
Roberta Gonnella, Maria Saveria Gilardini Montani, Luisa Guttieri, Maria Anele Romeo, Roberta Santarelli & Mara Cirone. (2021) IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation. Biomedicines 9:2, pages 118.
Crossref
Crossref
Karina Ckless & Rajesh Sunasee. 2021. Mitochondrial Dysfunction and Nanotherapeutics. Mitochondrial Dysfunction and Nanotherapeutics
499
524
.
Qi Nan Wu, Ling Zhang & Bing Chen. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
247
253
.
Seung-Ju Yang, A Reum Han, Hye-Rim Choi, Kyouk Hwang, Eun-A Kim, Soo Young Choi & Sung-Woo Cho. (2020)
N
-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neurons
. BMB Reports 53:10, pages 527-532.
Crossref
Crossref
Tongjian Zhao, Jie Ma, Lulu Li, Wenjing Teng, Yafei Tian, Yongjun Ma, Wei Wang, Weiqun Yan & Ping Jiao. (2020) MKP-5 Relieves Lipotoxicity-Induced Islet β-Cell Dysfunction and Apoptosis via Regulation of Autophagy. International Journal of Molecular Sciences 21:19, pages 7161.
Crossref
Crossref
Ying Bai, Xueli Bao, Guangjian Jiang, Dongyu Ge, Weipeng He, Dandan Zhao, Yi Zhang, Ruijuan Dong, Jing Hua, Nan Yang, Fangfang Mo & Sihua Gao. (2020) Jiang Tang Xiao Ke Granule Protects Hepatic Tissue of Diabetic Mice Through Modulation of Insulin and Ras Signaling – A Bioinformatics Analysis of MicroRNAs and mRNAs Network. Frontiers in Pharmacology 11.
Crossref
Crossref
Wei Wang, Fang Zhang, Xin Yan & Qian Tan. (2020) Wnt7a regulates high autophagic and inflammatory response of epidermis in high-glucose environment. Burns 46:1, pages 121-127.
Crossref
Crossref
Pu Hong, Ruo-Nan Gu, Feng-Xian Li, Xiao-Xing Xiong, Wen-Bin Liang, Zhi-Jian You & Hong-Fei Zhang. (2019) NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes. Journal of Neuroinflammation 16:1.
Crossref
Crossref
Ji Hyun Shin & Dong-Hyung Cho. (2019) TMP21 regulates autophagy by modulating ROS production and mTOR activation. Biochemical and Biophysical Research Communications 518:4, pages 746-751.
Crossref
Crossref
J. Moura, P. Madureira, E.C. Leal, A.C. Fonseca & E. Carvalho. (2019) Immune aging in diabetes and its implications in wound healing. Clinical Immunology 200, pages 43-54.
Crossref
Crossref
Sulie L. Chang, Wenfei Huang, Haijun Han & Ilker K. Sariyer. (2019) Binge-Like Exposure to Ethanol Enhances Morphine's Anti-nociception in B6 Mice. Frontiers in Psychiatry 9.
Crossref
Crossref
Arvind Kumar Shukla, Joshua Spurrier, Irina Kuzina & Edward Giniger. (2019) Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5. Cell Reports 26:1, pages 131-144.e4.
Crossref
Crossref
Guang-Jiang Shi, Yan Li, Qiu-Hua Cao, Hong-Xi Wu, Xin-Ying Tang, Xing-Hua Gao, Jian-Qiang Yu, Zhen Chen & Yong Yang. (2019) In vitro and in vivo evidence that quercetin protects against diabetes and its complications: A systematic review of the literature. Biomedicine & Pharmacotherapy 109, pages 1085-1099.
Crossref
Crossref
J. Kosacka, M. Nowicki, S. Paeschke, P. Baum, M. Blüher & N. Klöting. (2018) Up-regulated autophagy: as a protective factor in adipose tissue of WOKW rats with metabolic syndrome. Diabetology & Metabolic Syndrome 10:1.
Crossref
Crossref
Marina Sokolova, Afaf Sahraoui, Merete Høyem, Jonas Øgaard, Egil Lien, Pål Aukrust, Arne Yndestad, Trine Ranheim & Hanne Scholz. (2018) NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction. American Journal of Physiology-Endocrinology and Metabolism 315:5, pages E912-E923.
Crossref
Crossref
Alireza Kazemi, Mohammadreza Sadri, Mohammad Houshmand, Narjes Yazdi, Mahin Nikougoftar Zarif, Ali Anjam-Najmedini, Rezvan Tavakoli, Mohammad Ojaghi, Mansoureh Ajami, Monireh Ajami & Amir Atashi. (2018) The anticancer effects of pharmacological inhibition of autophagy in acute erythroid leukemia cells. Anti-Cancer Drugs 29:10, pages 944-955.
Crossref
Crossref
Wenbin Zheng, Jing Zhou, Shasha Song, Wen Kong, Wenfang Xia, Lulu Chen & Tianshu Zeng. (2018) Dipeptidyl-Peptidase 4 Inhibitor Sitagliptin Ameliorates Hepatic Insulin Resistance by Modulating Inflammation and Autophagy in ob/ob Mice. International Journal of Endocrinology 2018, pages 1-11.
Crossref
Crossref
Suryun Jung, Nayoung Ahn, Jusik Park & Kijin Kim. (2018) Effects of 8 Weeks Calorie Reduction and Resistance Exercise on Traf2-NFkB-mTOR and SIRT1-FoxO1 Signal Expression of Cardiac Muscle in High-fat Induced Obese Middle-Aged Rats. Exercise Science 27:2, pages 126-133.
Crossref
Crossref
Jie Yin, Wenkai Ren, Shuai Chen, Yuying Li, Hui Han, Jing Gao, Gang Liu, Xin Wu, Tiejun Li, Sung Woo Kim & Yulong Yin. (2018) Metabolic Regulation of Methionine Restriction in Diabetes. Molecular Nutrition & Food Research 62:10, pages 1700951.
Crossref
Crossref
Laura M Laiglesia, Silvia Lorente-Cebrián, Miguel López-Yoldi, Raquel Lanas, Neira Sáinz, Jose Alfredo Martínez & Maria J. Moreno-Aliaga. (2018) Maresin 1 inhibits TNF-alpha-induced lipolysis and autophagy in 3T3-L1 adipocytes. Journal of Cellular Physiology 233:3, pages 2238-2246.
Crossref
Crossref
Cosimo De Nunzio, Simona Giglio, Antonella Stoppacciaro, Mauro Gacci, Roberto Cirombella, Emidio Luciani, Andrea Tubaro & Andrea Vecchione. (2017) Autophagy deactivation is associated with severe prostatic inflammation in patients with lower urinary tract symptoms and benign prostatic hyperplasia. Oncotarget 8:31, pages 50904-50910.
Crossref
Crossref
Jai-Sing Yang, Chi-Cheng Lu, Sheng-Chu Kuo, Yuan-Man Hsu, Shih-Chang Tsai, Shih-Yin Chen, Yng-Tay Chen, Ying-Ju Lin, Yu-Chuen Huang, Chao-Jung Chen, Wei-De Lin, Wen-Lin Liao, Wei-Yong Lin, Yu-Huei Liu, Jinn-Chyuan Sheu & Fuu-Jen Tsai. (2017) Autophagy and its link to type II diabetes mellitus. BioMedicine 7:2, pages 8.
Crossref
Crossref
Erin Harberts, Kerry Heitmiller & Anthony A. Gaspari. 2017. Clinical and Basic Immunodermatology. Clinical and Basic Immunodermatology
201
217
.
Jia-Jing Yin, Guangying Xie, Ning Zhang & Yanbo Li. (2016) Inhibiting autophagy promotes endoplasmic reticulum stress and the ROS-induced nod-like receptor 3-dependent proinflammatory response in HepG2 cells. Molecular Medicine Reports 14:4, pages 3999-4007.
Crossref
Crossref
Tianshu Zeng, Jing Zhou, Linzheng He, Juan Zheng, Lulu Chen, Chaodong Wu & Wenfang Xia. (2016) Blocking Nuclear Factor-Kappa B Protects against Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice. PLOS ONE 11:3, pages e0149677.
Crossref
Crossref
Yongeun Kim, Wei Wang, Meshail Okla, Inhae Kang, Regis Moreau & Soonkyu Chung. (2016) Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes. Journal of Lipid Research 57:1, pages 66-76.
Crossref
Crossref
J. Kosacka, M. Kern, N. Klöting, S. Paeschke, A. Rudich, Y. Haim, M. Gericke, H. Serke, M. Stumvoll, I. Bechmann, M. Nowicki & M. Blüher. (2015) Autophagy in adipose tissue of patients with obesity and type 2 diabetes. Molecular and Cellular Endocrinology 409, pages 21-32.
Crossref
Crossref
Linying Shi, Ting Zhang, Xinyu Liang, Qin Hu, Juan Huang, Yong Zhou, Mingliang Chen, Qianyong Zhang, Jundong Zhu & Mantian Mi. (2015) Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway. Molecular and Cellular Endocrinology 409, pages 92-102.
Crossref
Crossref
Helen E. Gruber, Gretchen L. Hoelscher, Jane A. Ingram, Synthia Bethea & Edward N. HanleyJrJr. (2015) Autophagy in the Degenerating Human Intervertebral Disc. Spine 40:11, pages 773-782.
Crossref
Crossref
Min Kim, Ji Seon Lee, Joo En Oh, Jinyan Nan, Hakmo Lee, Hye Seung Jung, Sung Soo Chung & Kyong Soo Park. (2015) SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction. PLOS ONE 10:4, pages e0124744.
Crossref
Crossref
João D. MartinsJoana LiberalAna SilvaIsabel FerreiraBruno Miguel NevesMaria Teresa Cruz. (2015) Autophagy and Inflammasome Interplay. DNA and Cell Biology 34:4, pages 274-281.
Crossref
Crossref
Zhao Yang, Lina Zhong, Shanchuan Zhong, Ronghua Xian & Bangqing Yuan. (2015) Hypoxia induces microglia autophagy and neural inflammation injury in focal cerebral ischemia model. Experimental and Molecular Pathology 98:2, pages 219-224.
Crossref
Crossref
Guanghong Jia & James R. Sowers. (2015) Autophagy: A housekeeper in cardiorenal metabolic health and disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1852:2, pages 219-224.
Crossref
Crossref
Nazira El-Hage, Myosotys Rodriguez, Seth M. Dever, Ruturaj R. Masvekar, David A. Gewirtz & John J. Shacka. (2015) HIV-1 and Morphine Regulation of Autophagy in Microglia: Limited Interactions in the Context of HIV-1 Infection and Opioid Abuse. Journal of Virology 89:2, pages 1024-1035.
Crossref
Crossref
Ying Liu, Rengasamy Palanivel, Esther Rai, Min Park, Tim V. Gabor, Michael P. Scheid, Aimin Xu & Gary Sweeney. (2015) Adiponectin Stimulates Autophagy and Reduces Oxidative Stress to Enhance Insulin Sensitivity During High-Fat Diet Feeding in Mice. Diabetes 64:1, pages 36-48.
Crossref
Crossref
Han Liu, Ming-ming Cao, Yang Wang, Le-chen Li, Li-bo Zhu, Guang-ying Xie & Yan-bo Li. (2015) Endoplasmic reticulum stress is involved in the connection between inflammation and autophagy in type 2 diabetes. General and Comparative Endocrinology 210, pages 124-129.
Crossref
Crossref
Eun-Jung Park, Dong-Hyuk Choi, Younghun Kim, Eun-Woo Lee, Jaewhan Song, Myung-Haing Cho, Jae-Ho Kim & Sang-Wook Kim. (2014) Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells. Toxicology in Vitro 28:8, pages 1402-1412.
Crossref
Crossref
Guanghong Jia, Annayya R. Aroor, Luis A. Martinez-Lemus & James R. Sowers. (2014) Overnutrition, mTOR signaling, and cardiovascular diseases. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 307:10, pages R1198-R1206.
Crossref
Crossref
Jia Liu, Ying Tang, Zhihui Feng, Chen Hou, Hui Wang, Jiong Yan, Jing Liu, Weili Shen, Weijin Zang, Jiankang Liu & Jiangang Long. (2014) Acetylated FoxO1 mediates high-glucose induced autophagy in H9c2 cardiomyoblasts: Regulation by a polyphenol -(−)-epigallocatechin-3-gallate. Metabolism 63:10, pages 1314-1323.
Crossref
Crossref
Wenbin Zhang, Gang Zhao, Xiaona Hu, Min Wang, Hua Li, Yong Ye, Qijun Du, Jin Yao, Zhijun Bao, Wei Hong, Guosheng Fu, Junbo Ge & Zhaohui Qiu. (2014)
Aliskiren‐attenuated myocardium apoptosis
via
regulation of autophagy and connexin‐43 in aged spontaneously hypertensive rats
. Journal of Cellular and Molecular Medicine 18:7, pages 1247-1256.
Crossref
Crossref
Stefan W. Ryter, Ja Kun Koo & Augustine M.K. Choi. (2014) Molecular regulation of autophagy and its implications for metabolic diseases. Current Opinion in Clinical Nutrition and Metabolic Care 17:4, pages 329-337.
Crossref
Crossref
Rosa Lavieri, Patrizia Piccioli, Sonia Carta, Laura Delfino, Patrizia Castellani & Anna Rubartelli. (2014) TLR Costimulation Causes Oxidative Stress with Unbalance of Proinflammatory and Anti-Inflammatory Cytokine Production. The Journal of Immunology 192:11, pages 5373-5381.
Crossref
Crossref
Sheau‐Fang Ng, Ruby C. Y. Lin, Christopher A. Maloney, Neil A. Youngson, Julie A. Owens & Margaret J. Morris. (2014) Paternal high‐fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring. The FASEB Journal 28:4, pages 1830-1841.
Crossref
Crossref
Arnaud François, Faraj Terro, Thierry Janet, Agnès Rioux Bilan, Marc Paccalin & Guylène Page. (2013) Involvement of interleukin-1β in the autophagic process of microglia: relevance to Alzheimer’s disease. Journal of Neuroinflammation 10:1.
Crossref
Crossref
Jae-Min Yuk & Eun-Kyeong Jo. (2013) Crosstalk between Autophagy and Inflammasomes. Molecules and Cells 36:5, pages 393-399.
Crossref
Crossref