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Research Paper

Wild-type and mutant p53 proteins interact with mitochondrial caspase-3

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Pages 740-745 | Received 01 Dec 2010, Accepted 21 Jan 2011, Published online: 15 Apr 2011

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Anneleen Steels, Adriaan Verhelle, Olivier Zwaenepoel & Jan Gettemans. (2018) Intracellular displacement of p53 using transactivation domain (p53 TAD) specific nanobodies. mAbs 10:7, pages 1045-1059.
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Cédric Castrogiovanni, Marie Vandaudenard, Béranger Waterschoot, Olivier De Backer & Patrick Dumont. (2015) Decrease of mitochondrial p53 during late apoptosis is linked to its dephosphorylation on serine 20. Cancer Biology & Therapy 16:9, pages 1296-1307.
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N D Marchenko & U M Moll. (2014) Mitochondrial death functions of p53. Molecular & Cellular Oncology 1:2.
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Jacqueline L.Y. Chee, Suzan Saidin, David P. Lane, Sai Mun Leong, Jacqueline E. Noll, Paul M. Neilsen, Yi Ting Phua, Hani Gabra & Tit Meng Lim. (2013) Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9. Cell Cycle 12:2, pages 278-288.
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Jacob Haagsma, Bart Kolendowski, Adrian Buensuceso, Yudith Ramos Valdes, Gabriel E. DiMattia & Trevor G. Shepherd. (2023) Gain-of-function p53R175H blocks apoptosis in a precursor model of ovarian high-grade serous carcinoma. Scientific Reports 13:1.
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Yali Su, Yingying Sai, Linfeng Zhou, Zeliang Liu, Panyan Du, Jinghua Wu & Jinghua Zhang. (2022) Current insights into the regulation of programmed cell death by TP53 mutation in cancer. Frontiers in Oncology 12.
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Basudeb Das, Swapnil Sahoo & Bibekanand Mallick. (2022) HIWI2 induces G2/M cell cycle arrest and apoptosis in human fibrosarcoma via the ROS/DNA damage/p53 axis. Life Sciences 293, pages 120353.
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Lu Yang, Yun Li, Arup Bhattacharya & Yuesheng Zhang. (2021) Loss of peptidase D binding restores the tumor suppressor functions of oncogenic p53 mutants. Communications Biology 4:1.
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Oleg V. Dolgikh, Dina G. Dianova, Inga N. Alikina & Alexander V. Krivtsov. (2021) The benzene impact on programmed death of sperm cell. Hygiene and sanitation 100:10, pages 1060-1063.
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Yavuz Erden. (2021) Sour black mulberry (Morus nigra L.) causes cell death by decreasing mutant p53 expression in HT-29 human colon cancer cells. Food Bioscience 42, pages 101113.
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Giuseppina Barrera, Marie Angele Cucci, Margherita Grattarola, Chiara Dianzani, Giuliana Muzio & Stefania Pizzimenti. (2021) Control of Oxidative Stress in Cancer Chemoresistance: Spotlight on Nrf2 Role. Antioxidants 10:4, pages 510.
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Qian Hao, Yajie Chen & Xiang Zhou. (2020) The Janus Face of p53-Targeting Ubiquitin Ligases. Cells 9:7, pages 1656.
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Ines Müller, Elwira Strozyk, Sebastian Schindler, Stefan Beissert, Htoo Zarni Oo, Thomas Sauter, Philippe Lucarelli, Sebastian Raeth, Angelika Hausser, Nader Al Nakouzi, Ladan Fazli, Martin E. Gleave, He Liu, Hans-Uwe Simon, Henning Walczak, Douglas R. Green, Jiri Bartek, Mads Daugaard & Dagmar Kulms. (2020) Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28. Molecular Cell 77:5, pages 970-984.e7.
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Giovanni Blandino, Fabio Valenti, Andrea Sacconi & Silvia Di Agostino. (2020) Wild type- and mutant p53 proteins in mitochondrial dysfunction: emerging insights in cancer disease. Seminars in Cell & Developmental Biology 98, pages 105-117.
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Yan Stein, Varda Rotter & Ronit Aloni-Grinstein. (2019) Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis. International Journal of Molecular Sciences 20:24, pages 6197.
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Jessica J. Miller, Anaïs Blanchet, Christophe Orvain, Lucienne Nouchikian, Yasmin Reviriot, Ryan M. Clarke, Diego Martelino, Derek Wilson, Christian Gaiddon & Tim Storr. (2019) Bifunctional ligand design for modulating mutant p53 aggregation in cancer. Chemical Science 10:46, pages 10802-10814.
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Xin-yang Li, Ting-jian Zhang, Mohamed Olounfeh Kamara, Guo-qing Lu, Hai-li Xu, De-pu Wang & Fan-hao Meng. (2019) Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity. Cell Death & Disease 10:7.
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Xiang Zhou, Qian Hao & Hua Lu. (2019) Mutant p53 in cancer therapy—the barrier or the path. Journal of Molecular Cell Biology 11:4, pages 293-305.
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Germana Castelli, Elvira Pelosi & Ugo Testa. (2019) Emerging Therapies for Acute Myelogenus Leukemia Patients Targeting Apoptosis and Mitochondrial Metabolism. Cancers 11:2, pages 260.
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Fiamma Mantovani, Licio Collavin & Giannino Del Sal. (2018) Mutant p53 as a guardian of the cancer cell. Cell Death & Differentiation 26:2, pages 199-212.
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A. I. Stukan, V. A. Porhanov, V. N. Bodnya, O. Yu. Chuhraj, Y. M. Makarova & I. S. Elizbaryan. (2018) Molecular and genetic profile of head and neck squamous cell carcinoma. Medical Herald of the South of Russia 9:3, pages 50-57.
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Yuhong Pan, Pengfei Li, Renyong Jia, Mingshu Wang, Zhongqiong Yin & Anchun Cheng. (2018) Regulation of Apoptosis During Porcine Circovirus Type 2 Infection. Frontiers in Microbiology 9.
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Aaheli Roy Choudhury & Keshav K. Singh. (2017) Mitochondrial determinants of cancer health disparities. Seminars in Cancer Biology 47, pages 125-146.
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Fiamma Mantovani, Dawid Walerych & Giannino Del Sal. (2016) Targeting mutant p53 in cancer: a long road to precision therapy. The FEBS Journal 284:6, pages 837-850.
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Carlotta Giorgi, Massimo Bonora, Sonia Missiroli, Claudia Morganti, Giampaolo Morciano, Mariusz R. Wieckowski & Paolo Pinton. (2016) Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants. Frontiers in Oncology 6.
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Anna Comel, Giovanni Sorrentino, Valeria Capaci & Giannino Del Sal. (2014) The cytoplasmic side of p53's oncosuppressive activities. FEBS Letters 588:16, pages 2600-2609.
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Nadi T. Wickramasekera & Gokul M. Das. (2014) Tumor suppressor p53 and estrogen receptors in nuclear–mitochondrial communication. Mitochondrion 16, pages 26-37.
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Patricia A.J. Muller & Karen H. Vousden. (2014) Mutant p53 in Cancer: New Functions and Therapeutic Opportunities. Cancer Cell 25:3, pages 304-317.
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Zhenhong Zhuang, Daibin Yang, Yaling Huang & Shihua Wang. (2013) Study on the Apoptosis Mechanism Induced by T-2 Toxin. PLoS ONE 8:12, pages e83105.
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Fabiola Porta, Gerda E. M. Lamers, Jess Morrhayim, Antonia Chatzopoulou, Marcel Schaaf, Hans den Dulk, Claude Backendorf, Jeffrey I. Zink & Alexander Kros. (2013) Folic Acid-Modified Mesoporous Silica Nanoparticles for Cellular and Nuclear Targeted Drug Delivery. Advanced Healthcare Materials 2:2, pages 281-286.
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Razmik Mirzayans, Bonnie Andrais, April Scott & David Murray. (2012) New Insights into p53 Signaling and Cancer Cell Response to DNA Damage: Implications for Cancer Therapy. Journal of Biomedicine and Biotechnology 2012, pages 1-16.
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