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Research Paper

TOFA (5-tetradecyl-oxy-2-furoic acid) reduces fatty acid synthesis, inhibits expression of AR, neuropilin-1 and Mcl-1 and kills prostate cancer cells independent of p53 status

Pages 80-85 | Received 16 Feb 2011, Accepted 02 Apr 2011, Published online: 01 Jul 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Connie C. Qiu, Atilio E. Atencio & Stefania Gallucci. (2019) Inhibition of fatty acid metabolism by etomoxir or TOFA suppresses murine dendritic cell activation without affecting viability. Immunopharmacology and Immunotoxicology 41:3, pages 361-369.
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Chao Wang, Jun Ma, Nan Zhang, Qianlan Yang, Yue Jin & Yu Wang. (2015) The acetyl-CoA carboxylase enzyme: a target for cancer therapy?. Expert Review of Anticancer Therapy 15:6, pages 667-676.
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Natalya V. Guseva, Oskar W. Rokhlin, Rebecca A. Glover & Michael B. Cohen. (2012) P53 and the proteasome regulate androgen receptor activity. Cancer Biology & Therapy 13:7, pages 553-558.
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SHU LI, LIHUA QIU, BUCHU WU, HAORAN SHEN, JING ZHU, LIANG ZHOU, LIYING GU & WEN DI. (2013) TOFA suppresses ovarian cancer cell growth in vitro and in vivo. Molecular Medicine Reports 8:2, pages 373-378.
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