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Research Paper

Enhanced antitumor activity of low-dose continuous administration schedules of topotecan in prostate cancer

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Pages 407-420 | Received 21 Jan 2011, Accepted 07 Jun 2011, Published online: 01 Sep 2011

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Mohammad Hassan Hodroj, Achraf Jardaly, Sarah Abi Raad, Annalise Zouein & Sandra Rizk. (2018) Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway. Cancer Management and Research 10, pages 1079-1088.
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Taraswi Mitra Ghosh, Suman Mazumder, Joshua Davis, Jyoti Yadav, Ayuba Akinpelu, Ahmed Alnaim, Harish Kumar, Razan Waliagha, Allison E. Church Bird, Soroush Rais-Bahrami, R. Curtis Bird, Panagiotis Mistriotis, Amarjit Mishra, Clayton C. Yates, Amit K. Mitra & Robert D. Arnold. (2023) Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial–mesenchymal Transition in Aggressive Variant Prostate Cancers. Cancer Research Communications 3:7, pages 1286-1311.
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Joshua T. Davis, Taraswi Mitra Ghosh, Suman Mazumder, Amit Mitra, Richard Curtis Bird & Robert D. Arnold. (2023) Extended Exposure Topotecan Significantly Improves Long-Term Drug Sensitivity by Decreasing Malignant Cell Heterogeneity and by Preventing Epithelial–Mesenchymal Transition. International Journal of Molecular Sciences 24:10, pages 8490.
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Mujibur Khan, Md. Mahmudul Hasan, Anne Barnett, Raziye Piranlioglu, Mohammad Rashid, Ahmet Alptekin & Ali Arbab. (2022) Co-axial electrospraying of injectable multi-cancer drugs nanocapsules with polymer shells for targeting aggressive breast cancers. Cancer Nanotechnology 13:1.
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Taraswi Mitra Ghosh, Teeratas Kansom, Suman Mazumder, Joshua Davis, Ahmed S. Alnaim, Shanese L. Jasper, Chu Zhang, Aedan Bird, Praneet Opanasopit, Amit K. Mitra & Robert D. Arnold. (2022) The Andrographolide Analogue 3A.1 Synergizes with Taxane Derivatives in Aggressive Metastatic Prostate Cancers by Upregulation of Heat Shock Proteins and Downregulation of MAT2A-Mediated Cell Migration and Invasion. Journal of Pharmacology and Experimental Therapeutics 380:3, pages 180-201.
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Taraswi Mitra Ghosh, Jason White, Joshua Davis, Suman Mazumder, Teeratas Kansom, Elena Skarupa, Grafton S. Barnett, Gary A. Piazza, R. Curtis Bird, Amit K. Mitra, Clayton Yates, Brian S. Cummings & Robert D. Arnold. (2021) Identification and Characterization of Key Differentially Expressed Genes Associated With Metronomic Dosing of Topotecan in Human Prostate Cancer. Frontiers in Pharmacology 12.
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Tuba Tarhan, Bilsen Tural & Servet Tural. (2019) Synthesis and characterization of new branched magnetic nanocomposite for loading and release of topotecan anti-cancer drug. Journal of Analytical Science and Technology 10:1.
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Nhat D. Quach, Sukhneeraj Pal Kaur, Matthew W. Eggert, Lishann Ingram, Deepraj Ghosh, Sheela Sheth, Tamas Nagy, Michelle R. Dawson, Robert D. Arnold & Brian S. Cummings. (2019) Paradoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth. Scientific Reports 9:1.
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Maharjan, Pangeni, Jha, Choi, Chang, Choi, Park & Byun. (2019) Anti-Angiogenic Effect of Orally Available Pemetrexed for Metronomic Chemotherapy. Pharmaceutics 11:7, pages 332.
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Teresa Di Desidero, Ping Xu, Shan Man, Guido Bocci & Robert S. Kerbel. (2015) Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer. Oncotarget 6:40, pages 42396-42410.
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Rebecca A. Previs, Guillermo N. Armaiz-Pena, Yvonne G. Lin, Ashley N. Davis, Sunila Pradeep, Heather J. Dalton, Jean M. Hansen, William M. Merritt, Alpa M. Nick, Robert R. Langley, Robert L. Coleman & Anil K. Sood. (2015) Dual Metronomic Chemotherapy with Nab-Paclitaxel and Topotecan Has Potent Antiangiogenic Activity in Ovarian Cancer. Molecular Cancer Therapeutics 14:12, pages 2677-2686.
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Amar Jyoti, Kyle D. Fugit, Pallavi Sethi, Ronald C. McGarry, Bradley D. Anderson & Meenakshi Upreti. (2015) An in vitro assessment of liposomal topotecan simulating metronomic chemotherapy in combination with radiation in tumor-endothelial spheroids. Scientific Reports 5:1.
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Antonio Gnoni, Nicola Silvestris, Antonella Licchetta, Daniele Santini, Mario Scartozzi, Roberto Ria, Salvatore Pisconti, Fausto Petrelli, Angelo Vacca & Vito Lorusso. (2015) Metronomic chemotherapy from rationale to clinical studies: A dream or reality?. Critical Reviews in Oncology/Hematology 95:1, pages 46-61.
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Annabelle Chow, Amy Wong, Giulio Francia, Shan Man, Robert S. Kerbel & Urban Emmenegger. (2013) Preclinical analysis of resistance and cross-resistance to low-dose metronomic chemotherapy. Investigational New Drugs 32:1, pages 47-59.
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J. N. Mock, L. J. Costyn, S. L. Wilding, R. D. Arnold & B. S. Cummings. (2013) Evidence for distinct mechanisms of uptake and antitumor activity of secretory phospholipase A2 responsive liposome in prostate cancer. Integrative Biology 5:1, pages 172-182.
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