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Sadhan Mondal. (2024) Anticancer Potential of Biologically Active Diosgenin and its Derivatives:
An Update. Current Traditional Medicine 10:1.
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Antony Joseph Velanganni Arockiam, Nithya Ganesan & Devan Umapathy. (2023) DIOSGENIN AT THE CELLULAR LEVEL AS A CANCER REMEDIAL AGENT. Indian Drugs 60:04, pages 7-16.
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Wasita Witayateeraporn, Hien Minh Nguyen, Duc Viet Ho, Hoai Thi Nguyen, Pithi Chanvorachote, Chanida Vinayanuwattikun & Varisa Pongrakhananon. (2022) Aspiletrein A Induces Apoptosis Cell Death via Increasing Reactive Oxygen Species Generation and AMPK Activation in Non-Small-Cell Lung Cancer Cells. International Journal of Molecular Sciences 23:16, pages 9258.
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Prabhakar Semwal, Sakshi Painuli, Tareq Abu-Izneid, Abdur Rauf, Anshu Sharma, Sevgi Durna Daştan, Manoj Kumar, Mohammed M. Alshehri, Yasaman Taheri, Rajib Das, Saikat Mitra, Talha Bin Emran, Javad Sharifi-Rad, Daniela Calina & William C. Cho. (2022) Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives. Oxidative Medicine and Cellular Longevity 2022, pages 1-17.
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Lei Li, Libo Yu, Xiansheng Cao, Chao Zhang, Qi Liu & Jun Chen. (2022) Comparative Analysis of Proteomic of Curcumin Reversing Multidrug Resistance in HCT-8/VCR Cells. Journal of Oncology 2022, pages 1-8.
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Shinjini Bandopadhyay, Uttpal Anand, Vijaykumar Shivaji Gadekar, Niraj Kumar Jha, Piyush Kumar Gupta, Tapan Behl, Manoj Kumar, Radha, Mahipal S. Shekhawat & Abhijit Dey. (2021) Dioscin: A review on pharmacological properties and therapeutic values. BioFactors 48:1, pages 22-55.
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Md Afjalus Siraj, Md. Arman Islam, Md. Abdullah Al Fahad, Habiba Rahman Kheya, Jianbo Xiao & Jesus Simal-Gandara. (2021) Cancer Chemopreventive Role of Dietary Terpenoids by Modulating Keap1-Nrf2-ARE Signaling System—A Comprehensive Update. Applied Sciences 11:22, pages 10806.
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Izabella Jastrzebska, Pawel A. Grzes, Katarzyna Niemirowicz-Laskowska & Halina Car. (2021) Selenosteroids - promising hybrid compounds with pleiotropic biological activity: synthesis and biological aspects. The Journal of Steroid Biochemistry and Molecular Biology 213, pages 105975.
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Ruomiao Li, Yan Qi, Qianhui Yuan, Lina Xu, Meng Gao, Youwei Xu, Xu Han, Lianhong Yin & Chuntong Liu. (2021) Protective effects of dioscin against isoproterenol-induced cardiac hypertrophy via adjusting PKCε/ERK-mediated oxidative stress. European Journal of Pharmacology 907, pages 174277.
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Shinya Okubo, Tomoe Ohta, Yukihiro Shoyama & Takuhiro Uto. (2021) Steroidal Saponins Isolated from the Rhizome of Dioscorea tokoro Inhibit Cell Growth and Autophagy in Hepatocellular Carcinoma Cells. Life 11:8, pages 749.
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Dey Parama, Monikongkona Boruah, Kumari Yachna, Varsha Rana, Kishore Banik, Choudhary Harsha, Krishan Kumar Thakur, Uma Dutta, Aditya Arya, Xinliang Mao, Kwang Seok Ahn & Ajaikumar B. Kunnumakkara. (2020) Diosgenin, a steroidal saponin, and its analogs: Effective therapies against different chronic diseases. Life Sciences 260, pages 118182.
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R. Sun, J. L. Gao, H. Chen, S. Liu & Z. Z. Tang. (2020) CbCYP716A261, a New β-Amyrin 28-Hydroxylase Involved in Conyzasaponin Biosynthesis from Conyza blinii. Molecular Biology 54:5, pages 719-729.
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Ze Zhang, Kun Han, Chunying WangChengyan Sun & Ning Jia. (2020) Dioscin Protects against Aβ1–42 Oligomers-Induced Neurotoxicity <i>via</i> the Function of SIRT3 and Autophagy. Chemical and Pharmaceutical Bulletin 68:8, pages 717-725.
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O. Michalak, P. Krzeczyński, M. Cieślak, P. Cmoch, M. Cybulski, K. Królewska-Golińska, J. Kaźmierczak-Barańska, B. Trzaskowski & K. Ostrowska. (2020) Synthesis and anti–tumour, immunomodulating activity of diosgenin and tigogenin conjugates. The Journal of Steroid Biochemistry and Molecular Biology 198, pages 105573.
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Danuta Sobolewska, Agnieszka Galanty, Karolina Grabowska, Justyna Makowska-Wąs, Dagmara Wróbel-Biedrawa & Irma Podolak. (2020) Saponins as cytotoxic agents: an update (2010–2018). Part I—steroidal saponins. Phytochemistry Reviews 19:1, pages 139-189.
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Longfei Yang, Shengnan Ren, Fei Xu, Zhiming Ma, Xin Liu & Lufei Wang. (2019) Recent Advances in the Pharmacological Activities of Dioscin. BioMed Research International 2019, pages 1-13.
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Wei Song, Shan Yan, Yi Li, Shan Feng, Jia-jiao Zhang & Jia-ru Li. (2019) Functional characterization of squalene epoxidase and NADPH-cytochrome P450 reductase in Dioscorea zingiberensis. Biochemical and Biophysical Research Communications 509:3, pages 822-827.
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Xufeng Tao, Lianhong Yin, Lina Xu & Jinyong Peng. (2018) Dioscin: A diverse acting natural compound with therapeutic potential in metabolic diseases, cancer, inflammation and infections. Pharmacological Research 137, pages 259-269.
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Ying-Shuo Zhang, Yi-Long Ma, Kiran Thakur, Sayed Sajid Hussain, Jun Wang, Qi Zhang, Jian-Guo Zhang & Zhao-Jun Wei. (2018) Molecular mechanism and inhibitory targets of dioscin in HepG2 cells. Food and Chemical Toxicology 120, pages 143-154.
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Shu Li, Binbin Cheng, Lixin Hou, Lanwei Huang, Yongkang Cui, Duo Xu, Xiaoping Shen & Shuang Li. (2018) Dioscin inhibits colon cancer cells’ growth by reactive oxygen species-mediated mitochondrial dysfunction and p38 and JNK pathways. Anti-Cancer Drugs 29:3, pages 234-242.
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Reinhard Dammann, Antje Richter, Adriana Jiménez, Michelle Woods, Miriam Küster & Chamindri Witharana. (2017) Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer. International Journal of Molecular Sciences 18:10, pages 2160.
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Lingling Si, Lina Xu, Lianhong Yin, Yan Qi, Xu Han, Youwei Xu, Yanyan Zhao, Kexin Liu & Jinyong Peng. (2017) Potent effects of dioscin against pancreatic cancer via miR-149-3P-mediated inhibition of the Akt1 signalling pathway. British Journal of Pharmacology 174:7, pages 553-568.
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A.A. Hamid, Tanu Kaushal, Raghib Ashraf, Arjun Singh, Amit Chand Gupta, Om Prakash, Jayanta Sarkar, Debabrata Chanda, D.U. Bawankule, Feroz Khan, Karuna Shanker, O.O. Aiyelaagbe & Arvind S. Negi. (2017) (22?,25R)-3?-Hydroxy-spirost-5-en-7-iminoxy-heptanoic acid exhibits anti-prostate cancer activity through caspase pathway. Steroids 119, pages 43-52.
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Chenbo Ding, Xiaobo Fan & Guoqiu Wu. (2017) Peroxiredoxin 1 - an antioxidant enzyme in cancer. Journal of Cellular and Molecular Medicine 21:1, pages 193-202.
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Guangxian Zhang, Xiancheng Zeng, Ren Zhang, Juan Liu, Weici Zhang, Yujun Zhao, Xiaoyuan Zhang, Zhixue Wu, Yuhui Tan, Yingya Wu & Biaoyan Du. (2016) Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3. Phytomedicine 23:12, pages 1329-1336.
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Xiao-Huang Xu, Ting Li, Chi Fong, Xiuping Chen, Xiao-Jia Chen, Yi-Tao Wang, Ming-Qing Huang & Jin-Jian Lu. (2016) Saponins from Chinese Medicines as Anticancer Agents. Molecules 21:10, pages 1326.
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Muhammad Ali Khan, Md. Mahbubur Rahman, Md. Nazmul Sardar, Md. Saiful Islam Arman, Md. Badrul Islam, Md. Jahangir Alam Khandakar, Mamunur Rashid, Golam Sadik & AHM Khurshid Alam. (2016) Comparative investigation of the free radical scavenging potential and anticancer property of Diospyros blancoi (Ebenaceae). Asian Pacific Journal of Tropical Biomedicine 6:5, pages 410-417.
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Xinwei Zhao, Lina Xu, Lingli Zheng, Lianhong Yin, Yan Qi, Xu Han, Youwei Xu & Jinyong Peng. (2016) Potent effects of dioscin against gastric cancer in vitro and in vivo. Phytomedicine 23:3, pages 274-282.
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Lingling Si, Lingli Zheng, Lina Xu, Lianhong Yin, Xu Han, Yan Qi, Youwei Xu, Changyuan Wang & Jinyong Peng. (2016) Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion. European Journal of Pharmacology 774, pages 105-117.
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Pranapda Aumsuwan, Shabana I. Khan, Ikhlas A. Khan, Zulfiqar Ali, Bharathi Avula, Larry A. Walker, Zia Shariat-Madar, William G. Helferich, Benita S. Katzenellenbogen & Asok K. Dasmahapatra. (2016) The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro. Archives of Biochemistry and Biophysics 591, pages 98-110.
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Anastasia Georgantzopoulou, Tommaso Serchi, Sébastien Cambier, Céline C. Leclercq, Jenny Renaut, Jia Shao, Marcin Kruszewski, Esther Lentzen, Patrick Grysan, Santhana Eswara, Jean-Nicolas Audinot, Servane Contal, Johanna Ziebel, Cédric Guignard, Lucien Hoffmann, AlberTinka J. Murk & Arno C. Gutleb. (2016) Effects of silver nanoparticles and ions on a co-culture model for the gastrointestinal epithelium. Particle and Fibre Toxicology 13:1.
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Lianhong Yin, Lingli Zheng, Lina Xu, Deshi Dong, Xu Han, Yan Qi, Yanyan Zhao, Youwei Xu & Jinyong Peng. (2015) In-silico prediction of drug targets, biological activities, signal pathways and regulating networks of dioscin based on bioinformatics. BMC Complementary and Alternative Medicine 15:1.
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Murli Mishra, Hong Jiang, Lisha Wu, Hedy A. Chawsheen & Qiou Wei. (2015) The sulfiredoxin?peroxiredoxin (Srx?Prx) axis in cell signal transduction and cancer development. Cancer Letters 366:2, pages 150-159.
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Hye Lim Lee, Mi Hee Park, Dong Ju Son, Ho Sueb Song, Jung Hyun Kim, Seong Cheol Ko, Min Jong Song, Won Hyoung Lee, Joo Hee Yoon, Young Wan Ham, Sang Bae Han & Jin Tae Hong. (2015) Anti-cancer effect of snake venom toxin through down regulation of AP-1 mediated PRDX6 expression. Oncotarget 6:26, pages 22139-22151.
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He Zhu, Jin-Di Xu, Qian Mao, Hong Shen, Ming Kong, Jian-Ping Chen & Song-Lin Li. (2015) Metabolic profiles of dioscin in rats revealed by ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry. Biomedical Chromatography 29:9, pages 1415-1421.
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Laura L. Romero-Hernández, Penélope Merino-Montiel, Sara Montiel-Smith, Socorro Meza-Reyes, José Luis Vega-Báez, Ibane Abasolo, Simó SchwartzJr.Jr., Óscar López & José G. Fernández-Bolaños. (2015) Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile. European Journal of Medicinal Chemistry 99, pages 67-81.
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Yin Sim Tor, Latifah Saiful Yazan, Jhi Biau Foo, Nurdin Armania, Yoke Kqueen Cheah, Rasedee Abdullah, Mustapha Umar Imam, Norsharina Ismail & Maznah Ismail. (2014) Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa. BMC Complementary and Alternative Medicine 14:1.
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Jing Chen, Hui-min Li, Xue-nong Zhang, Chao-mei Xiong & Jin-lan Ruan. (2014) Dioscin-induced apoptosis of human LNCaP prostate carcinoma cells through activation of caspase-3 and modulation of Bcl-2 protein family. Journal of Huazhong University of Science and Technology [Medical Sciences] 34:1, pages 125-130.
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Weidong Lu, Zhongxue Fu, Hao Wang, Jihong Feng, Jinlai Wei & Jinbao Guo. (2013) Peroxiredoxin 2 is upregulated in colorectal cancer and contributes to colorectal cancer cells? survival by protecting cells from oxidative stress. Molecular and Cellular Biochemistry 387:1-2, pages 261-270.
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Hao Chen, Lina Xu, Lianhong Yin, Youwei Xu, Xu Han, Yan Qi, Yanyan Zhao, Kexin Liu & Jinyong Peng. (2014) iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells. PROTEOMICS 14:1, pages 51-73.
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Tae Yeon Kong, Hye Young Ji, Sang-Zin Choi, Miwon Son & Hye Suk Lee. (2013) Liquid Chromatography-tandem Mass Spectrometry for Quantification of Dioscin in Rat Plasma. Mass Spectrometry Letters 4:3, pages 55-58.
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Yongli Wei, Yousong Xu, Xu Han, Yan Qi, Lina Xu, Youwei Xu, Lianhong Yin, Huijun Sun, Kexin Liu & Jinyong Peng. (2013) Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway. Food and Chemical Toxicology 59, pages 118-128.
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H C Whitaker, D Patel, W J Howat, A Y Warren, J D Kay, T Sangan, J C Marioni, J Mitchell, S Aldridge, H J Luxton, C Massie, A G Lynch & D E Neal. (2013) Peroxiredoxin-3 is overexpressed in prostate cancer and promotes cancer cell survival by protecting cells from oxidative stress. British Journal of Cancer 109:4, pages 983-993.
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Chaohong Liu, Yun Wang, Chunchen Wu, Rongjuan Pei, Jianhua Song, Shiyun Chen & Xinwen Chen. (2013) Dioscin's antiviral effect in vitro. Virus Research 172:1-2, pages 9-14.
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Ha‐Jeong Kwon, Seung‐Hee Choi, Chang‐Seon Yoo, Hwa‐Young Choi, Soo‐Eon Lee & Yong‐Duk Park. (2013) Development of an analytical method for yam saponins using HPLC with pulsed amperometric detection at different column temperatures. Journal of Separation Science 36:4, pages 690-698.
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Ho-Yong Sohn. (2012) Dioscin sensitizes cells to TRAIL-induced apoptosis through downregulation of c-FLIP and Bcl-2. Oncology Reports.
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