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Research Paper

Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells

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Pages 567-574 | Received 04 Jan 2012, Accepted 20 Feb 2012, Published online: 01 May 2012

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Laurence Booth, Jane L Roberts, Adam Conley, Nichola Cruickshanks, Thomas Ridder, Steven Grant, Andrew Poklepovic & Paul Dent. (2014) HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells. Cancer Biology & Therapy 15:3, pages 305-316.
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Zabi Wardak & Kevin S Choe. (2013) Molecular pathways and potential therapeutic targets in glioblastoma multiforme. Expert Review of Anticancer Therapy 13:11, pages 1307-1318.
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Paul Dent. (2013) The multi-hit hypothesis in basal-like breast cancer. Cancer Biology & Therapy 14:9, pages 778-779.
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Lena Hess, Verena Moos, Arnel A. Lauber, Wolfgang Reiter, Michael Schuster, Natascha Hartl, Daniel Lackner, Thorina Boenke, Anna Koren, Paloma M. Guzzardo, Brigitte Gundacker, Anna Riegler, Petra Vician, Claudia Miccolo, Susanna Leiter, Mahesh B. Chandrasekharan, Terezia Vcelkova, Andrea Tanzer, Jun Qi Jun, James Bradner, Gerald Brosch, Markus Hartl, Christoph Bock, Tilmann Bürckstümmer, Stefan Kubicek, Susanna Chiocca, Srividya Bhaskara & Christian Seiser. (2022) A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation. PLOS Genetics 18:8, pages e1010376.
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Janaki Ramaiah Mekala, PrasannaSrinivasan Ramalingam, Nageswara Rao Moparthi & Vijay Kumar Kutala. 2022. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects 3259 3286 .
Janaki Ramaiah Mekala, PrasannaSrinivasan Ramalingam, Nageswara Rao Moparthi & Vijay Kumar Kutala. 2021. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects 1 28 .
Hyeok Jun Yun, Hee Jun Kim, Jungmin Kim, Sang Yong Kim, Hang-Seok Chang, Cheong Soo Park, Ho-Jin Chang & Ki Cheong Park. (2021) Synergistic Anticancer Activity of N-Hydroxy-7-(2-Naphthylthio) Heptanomide, Sorafenib, and Radiation Therapy in Patient-Derived Anaplastic Thyroid Cancer Models. International Journal of Molecular Sciences 22:2, pages 536.
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Alexandre Perla, Lívia Fratini, Paula S. Cardoso, Carolina Nör, André T. Brunetto, Algemir L. Brunetto, Caroline Brunetto de Farias, Mariane Jaeger & Rafael Roesler. (2020) Histone Deacetylase Inhibitors in Pediatric Brain Cancers: Biological Activities and Therapeutic Potential. Frontiers in Cell and Developmental Biology 8.
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Jane L. Roberts, Andrew Poklepovic, Laurence Booth & Paul Dent. (2020) The multi-kinase inhibitor lenvatinib interacts with the HDAC inhibitor entinostat to kill liver cancer cells. Cellular Signalling 70, pages 109573.
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Jiaqing Yi & Jiang Wu. (2018) Epigenetic regulation in medulloblastoma. Molecular and Cellular Neuroscience 87, pages 65-76.
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Laurence Booth, Jane L. Roberts, Andrew Poklepovic, John Kirkwood & Paul Dent. (2017) HDAC inhibitors enhance the immunotherapy response of melanoma cells. Oncotarget 8:47, pages 83155-83170.
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Laurence Booth, Jane L. Roberts, Cindy Sander, John Lee, John M. Kirkwood, Andrew Poklepovic & Paul Dent. (2017) The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo . Oncotarget 8:10, pages 16367-16386.
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Zhiqiang Zhang, Yunmin Wang, Jiehan Chen, Qijia Tan, Caijun Xie, Cong Li, Wengang Zhan & Mei Wang. (2016) Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity. Cancer Chemotherapy and Pharmacology 78:6, pages 1289-1296.
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Nestor Prieto-Domínguez, Raquel Ordóñez, Anna Fernández, Andres García-Palomo, Jordi Muntané, Javier González-Gallego & José L. Mauriz. (2016) Modulation of Autophagy by Sorafenib: Effects on Treatment Response. Frontiers in Pharmacology 7.
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David Bakhshinyan, Maleeha A. Qazi, Neha Garg, Chitra Venugopal, Nicole McFarlane & Sheila K. Singh. 2015. Principles of Stem Cell Biology and Cancer. Principles of Stem Cell Biology and Cancer 145 167 .
Clara Penas, Vasileios Stathias, Bryce K. Allen & Nagi G. Ayad. 2015. Epigenetic Cancer Therapy. Epigenetic Cancer Therapy 317 337 .
Ana-Maria Marino, Jeroen Frijhoff, Raul Calero, Ninib Baryawno, Arne Östman & John Inge Johnsen. (2014) Effects of epigenetic modificators in combination with small molecule inhibitors of receptor tyrosine kinases on medulloblastoma growth. Biochemical and Biophysical Research Communications 450:4, pages 1600-1605.
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Tobey J. MacDonald, Dolly Aguilera & Robert C. Castellino. (2014) The rationale for targeted therapies in medulloblastoma. Neuro-Oncology 16:1, pages 9-20.
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Carolina N?r, Felipe A. Sassi, Caroline Brunetto de Farias, Gilberto Schwartsmann, Ana Lucia Abujamra, Guido Lenz, Algemir Lunardi Brunetto & Rafael Roesler. (2013) The Histone Deacetylase Inhibitor Sodium Butyrate Promotes Cell Death and Differentiation and Reduces Neurosphere Formation in Human Medulloblastoma Cells. Molecular Neurobiology 48:3, pages 533-543.
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Hossein A. Hamed, Adly Yacoub, Margaret A. Park, Kellie Archer, Swadesh K. Das, Devanand Sarkar, Steven Grant, Paul B. Fisher & Paul Dent. (2013) Histone Deacetylase Inhibitors Interact with Melanoma Differentiation Associated-7/Interleukin-24 to Kill Primary Human Glioblastoma Cells. Molecular Pharmacology 84:2, pages 171-181.
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Nelson S. YeeAbid A. KaziRosemary K. Yee. (2013) Translating Discovery in Zebrafish Pancreatic Development to Human Pancreatic Cancer: Biomarkers, Targets, Pathogenesis, and Therapeutics. Zebrafish 10:2, pages 132-146.
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David T. W. Jones, Paul A. Northcott, Marcel Kool & Stefan M. Pfister. (2013) The Role of Chromatin Remodeling in Medulloblastoma. Brain Pathology 23:2, pages 193-199.
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