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Review

Retinoid Targets in Cancer Therapy and Chemoprevention

Pages 149-155 | Published online: 01 Mar 2003

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Alfeu Zanotto-Filho, Rafael Schröder & José Cláudio F. Moreira. (2008) Differential effects of retinol and retinoic acid on cell proliferation: A role for reactive species and redox-dependent mechanisms in retinol supplementation. Free Radical Research 42:9, pages 778-788.
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Hui-Ching Chuang, Hung-Yu Lin, Pei-Lin Liao, Chao-Cheng Huang, Li-Ling Lin, Wen-Ming Hsu & Jiin-Haur Chuang. (2020) Immunomodulator polyinosinic-polycytidylic acid enhances the inhibitory effect of 13-cis-retinoic acid on neuroblastoma through a TLR3-related immunogenic-apoptotic response. Laboratory Investigation 100:4, pages 606-618.
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Donghyeok Kim, Bo-hyun Choi, In-geun Ryoo & Mi-Kyoung Kwak. (2018) High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling. Cell Death & Disease 9:9.
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Adel Mahjoub, Jared A. Crasto, Jonathan Mandell, Mitchell S. Fourman, Rashmi Agarwal & Kurt R. Weiss. 2017. Osteosarcoma - Biology, Behavior and Mechanisms. Osteosarcoma - Biology, Behavior and Mechanisms.
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Palwinder Singh, Arun Kumar, Sukhmeet Kaur, Amrinder Singh, Muskan Gupta & Gurcharan Kaur. (2016) Stitching of tyrosine and 10H-acridin-9-one: turn-ON fluorescence in the narrow pH range 7.4–8.5 and intracellular labelling of cancer cells. MedChemComm 7:4, pages 632-635.
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Xia Xu, Shoujie Chai, Pingli Wang, Chenchen Zhang, Yiming Yang, Ying Yang & Kai Wang. (2015) Aldehyde dehydrogenases and cancer stem cells. Cancer Letters 369:1, pages 50-57.
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Mercedes Camacho, Zenaida Piñeiro, Sonia Alcolea, Jacinto García, Josep Balart, Ximena Terra, Francesc-Xavier Avilés-Jurado, Marta Soler, Miquel Quer, Xavier León & Luis Vila. (2015) Prostacyclin-synthase expression in head and neck carcinoma patients and its prognostic value in the response to radiotherapy. The Journal of Pathology 235:1, pages 125-135.
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Petr Chlapek, Jakub Neradil, Martina Redova, Karel Zitterbart, Jaroslav Sterba & Renata Veselska. (2014) The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression. Cancer Cell International 14:1.
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Keita Kanki, Yuji Akechi, Chisa Ueda, Hiroyuki Tsuchiya, Hiroki Shimizu, Naoki Ishijima, Kan Toriguchi, Etsuro Hatano, Kanenori Endo, Yasuaki Hirooka & Goshi Shiota. (2013) Biological and clinical implications of retinoic acid-responsive genes in human hepatocellular carcinoma cells. Journal of Hepatology 59:5, pages 1037-1044.
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M Ying, S Wang, Y Sang, P Sun, B Lal, C R Goodwin, H Guerrero-Cazares, A Quinones-Hinojosa, J Laterra & S Xia. (2011) Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition. Oncogene 30:31, pages 3454-3467.
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Heidi Fritz, Deborah Kennedy, Dean Fergusson, Rochelle Fernandes, Steve Doucette, Kieran Cooley, Andrew Seely, Stephen Sagar, Raimond Wong & Dugald Seely. (2011) Vitamin A and Retinoid Derivatives for Lung Cancer: A Systematic Review and Meta Analysis. PLoS ONE 6:6, pages e21107.
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Mariarita Perri, Attilio Pingitore, Erika Cione, Emma Vilardi, Valentina Perrone & Giuseppe Genchi. (2010) Proliferative and anti-proliferative effects of retinoic acid at doses similar to endogenous levels in Leydig MLTC-1/R2C/TM-3 cells. Biochimica et Biophysica Acta (BBA) - General Subjects 1800:9, pages 993-1001.
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Bogusz Trojanowicz, Carsten Sekulla, Kerstin Lorenz, Josef Köhrle, Rainer Finke, Henning Dralle & Cuong Hoang-Vu. (2010) Proteomic approach reveals novel targets for retinoic acid-mediated therapy of thyroid carcinoma. Molecular and Cellular Endocrinology 325:1-2, pages 110-117.
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Yasushi Toh, Eiji Oki, Kippei Ohgaki, Yasuo Sakamoto, Shuhei Ito, Akinori Egashira, Hiroshi Saeki, Yoshihiro Kakeji, Masaru Morita, Yoshihisa Sakaguchi, Takeshi Okamura & Yoshihiko Maehara. (2010) Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: molecular mechanisms of carcinogenesis. International Journal of Clinical Oncology 15:2, pages 135-144.
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John Patrick Alao. 2009. Checkpoint Controls and Targets in Cancer Therapy. Checkpoint Controls and Targets in Cancer Therapy 123 153 .
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William H. Catherino & Minnie Malik. (2007) Uterine leiomyomas express a molecular pattern that lowers retinoic acid exposure. Fertility and Sterility 87:6, pages 1388-1398.
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Konstantin H. Dragnev, W. Jeffrey Petty, Sumit J. Shah, Lionel D. Lewis, Candice C. Black, Vincent Memoli, William C. Nugent, Thomas Hermann, Andres Negro-Vilar, James R. Rigas & Ethan Dmitrovsky. (2007) A Proof-of-Principle Clinical Trial of Bexarotene in Patients with Non–Small Cell Lung Cancer. Clinical Cancer Research 13:6, pages 1794-1800.
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Konstantin H. Dragnev, Qing Feng, Yan Ma, Sumit J. Shah, Candice Black, Vincent Memoli, William Nugent, James R. Rigas, Sutisak Kitareewan, Sarah Freemantle & Ethan Dmitrovsky. 2007. Cancer Prevention. Cancer Prevention 235 243 .
Stewart Sell. (2006) Cancer Stem Cells and Differentiation Therapy. Tumor Biology 27:2, pages 59-70.
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Shumei Song, Scott M Lippman, Yiyu Zou, Xiaofeng Ye, Jaffer A Ajani & Xiao-chun Xu. (2005) Induction of cyclooxygenase-2 by benzo[a]pyrene diol epoxide through inhibition of retinoic acid receptor-β2 expression. Oncogene 24:56, pages 8268-8276.
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Eun Young Park, Alice Dillard, Elizabeth A. Williams, Erik T. Wilder, M. Reese Pepper & Michelle A. Lane. (2005) Retinol Inhibits the Growth of All-Trans -Retinoic Acid–Sensitive and All-Trans -Retinoic Acid–Resistant Colon Cancer Cells through a Retinoic Acid Receptor–Independent Mechanism . Cancer Research 65:21, pages 9923-9933.
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Basit Javaid & Richard J. Quigg. (2005) Treatment of glomerulonephritis: Will we ever have options other than steroids and cytotoxics?. Kidney International 67:5, pages 1692-1703.
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Ruan Elliott. (2005) Mechanisms of genomic and non-genomic actions of carotenoids. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1740:2, pages 147-154.
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Xiao-chun Xu, J. Jack Lee, Tsung-Teh Wu, Ashraful Hoque, Jeffer A. Ajani & Scott M. Lippman. (2005) Increased Retinoic Acid Receptor-β4 Correlates In vivo with Reduced Retinoic Acid Receptor-β2 in Esophageal Squamous Cell Carcinoma . Cancer Epidemiology, Biomarkers & Prevention 14:4, pages 826-829.
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Masaru Shinozaki, Dave S.B. Hoon, Armando E. Giuliano, Nora M. Hansen, He-Jing Wang, Roderick Turner & Bret Taback. (2005) Distinct Hypermethylation Profile of Primary Breast Cancer Is Associated with Sentinel Lymph Node Metastasis. Clinical Cancer Research 11:6, pages 2156-2162.
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Konstantin H. Dragnev, W. Jeffrey Petty, Yan Ma, James R. Rigas & Ethan Dmitrovsky. (2005) Nonclassical Retinoids and Lung Carcinogenesis. Clinical Lung Cancer 6:4, pages 237-244.
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Chien-Yun Hsiang, Shih-Lu Wu & Tin-Yun Ho. (2004) Activation of Activator Protein 1 and Extracellular Signal-Regulated Kinases in Human Hepatocellular Transformation. Tumor Biology 25:5-6, pages 313-320.
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