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Research Paper

The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer

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Pages 1284-1289 | Received 06 May 2012, Accepted 08 Aug 2012, Published online: 16 Aug 2012

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Claudio Festuccia. (2013) Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples. International Journal of Oncology.
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