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Research Paper

Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures

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Pages 625-637 | Received 22 Jan 2013, Accepted 07 Apr 2013, Published online: 10 May 2013

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Karina Kristoffersen, Mette Kjølhede Nedergaard, Mette Villingshøj, Rehannah Borup, Helle Broholm, Andreas Kjær, Hans Skovgaard Poulsen & Marie-Thérése Stockhausen. (2014) Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature. Cancer Biology & Therapy 15:7, pages 862-877.
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Marie-Thérése Stockhausen, Karina Kristoffersen, Louise Stobbe & Hans Skovgaard Poulsen. (2014) Differentiation of glioblastoma multiforme stem-like cells leads to downregulation of EGFR and EGFRvIII and decreased tumorigenic and stem-like cell potential. Cancer Biology & Therapy 15:2, pages 216-224.
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