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Cancer Biology & Therapy Volume 15, 2014 - Issue 6
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Research Paper

Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro

Giulia Marvaso Radiation Oncology; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, Italy
,
Agnese Barone Radiation Oncology; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, Italy
,
Nicola Amodio Medical Oncology Unit; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, Italy
,
Lavinia Raimondi Medical Oncology Unit; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, Italy
,
Valter Agosti Laboratory of Molecular Oncology; Magna Graecia University of Catanzaro; Catanzaro, Italy; CIS for Genomics and Molecular Pathology; Department of Experimental and Clinical Medicine; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, Italy
,
Emanuela Altomare Medical Oncology Unit; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, Italy
,
Valerio Scotti Malzoni Radiosurgery Center; Agropoli; Salerno, Italy
,
Angela Lombardi Department of Biochemistry, Biophysics and General Pathology; Second University of Naples; Naples, Italy
,
Roberto Bianco Department of Molecular and Clinical Endocrinology and Oncology; Biomorphological and Functional Sciences; University “Federico II” of Naples; Naples, Italy
,
Cataldo Bianco Radiation Oncology; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, Italy
,
Michele Caraglia Department of Biochemistry, Biophysics and General Pathology; Second University of Naples; Naples, ItalyCorrespondence[email protected] [email protected]
,
Pierfrancesco Tassone Medical Oncology Unit; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, Italy
&
Pierosandro Tagliaferri Medical Oncology Unit; Magna Graecia University of Catanzaro and T. Campanella Cancer Center; Catanzaro, ItalyCorrespondence[email protected] [email protected]
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Pages 797-805 | Received 02 Feb 2014, Accepted 16 Mar 2014, Published online: 21 Mar 2014

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Jun-Yi Wu, Zhong-Xia Wang, Guang Zhang, Xian Lu, Guang-Hui Qiang, Wei Hu, An-Lai Ji, Jun-Hua Wu & Chun-Ping Jiang. (2018) Targeted co-delivery of Beclin 1 siRNA and FTY720 to hepatocellular carcinoma by calcium phosphate nanoparticles for enhanced anticancer efficacy. International Journal of Nanomedicine 13, pages 1265-1280.
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Tristan Rupp, Solène Debasly, Laurie Genest, Guillaume Froget & Vincent Castagné. (2022) Therapeutic Potential of Fingolimod and Dimethyl Fumarate in Non-Small Cell Lung Cancer Preclinical Models. International Journal of Molecular Sciences 23:15, pages 8192.
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Yi YiWeijie HuWenchang Lv, Chongru Zhao, Mingchen Xiong, Min Wu, Qi Zhang & Yiping Wu. (2021) FTY720 Improves the Survival of Autologous Fat Grafting by Modulating Macrophages Toward M2 Polarization Via STAT3 Pathway. Cell Transplantation 30, pages 096368972110529.
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Tristan Rupp, Océane Pelouin, Laurie Genest, Christophe Legrand, Guillaume Froget & Vincent Castagné. (2021) Therapeutic potential of Fingolimod in triple negative breast cancer preclinical models. Translational Oncology 14:1, pages 100926.
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B. Anu, N.N. Namitha & K.B. Harikumar. 2021. Apoptosis in Health and Disease - Part A. Apoptosis in Health and Disease - Part A 259 274 .
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Rui-zhen Sun, Ying Fan, Xiao Liang, Tian-tian Gong, Qi Wang, Hui Liu, Zhi-yan Shan & Lei Lei. (2018) Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy. BioMed Research International 2018, pages 1-9.
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Antonio Leo, Rita Citraro, Nicola Amodio, Caterina De Sarro, Maria Eugenia Gallo Cantafio, Andrew Constanti, Giovambattista De Sarro & Emilio Russo. (2017) Fingolimod Exerts only Temporary Antiepileptogenic Effects but Longer-Lasting Positive Effects on Behavior in the WAG/Rij Rat Absence Epilepsy Model. Neurotherapeutics 14:4, pages 1134-1147.
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Fen Shi, Xiaoling Cao, Zhicheng Hu, Da Ma, Dong Guo, Jian Zhang, Changlin Zhang, Peng Liu, Shanqiang Qu, Jiayuan Zhu, Wuguo Deng & Bing Tang. (2017) Pleiotropic FTY720 Is a Specific and Potent Therapy for Hypertrophic Scars. Journal of Investigative Dermatology 137:7, pages 1552-1561.
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Dilruba Ahmed, Petra J. de Verdier, Charlotta Ryk, Oscar Lunqe, Per Stål & Jenny Flygare. (2015) FTY 720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib‐mediated cytotoxicity . Pharmacology Research & Perspectives 3:5.
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Heounjeong Go, Pil-Jong Kim, Yoon Kyung Jeon, Yong Mee Cho, Kyungeun Kim, Bong-Hee Park & Ja Yoon Ku. (2015) Sphingosine-1-phosphate receptor 1 (S1PR1) expression in non-muscle invasive urothelial carcinoma: Association with poor clinical outcome and potential therapeutic target. European Journal of Cancer 51:14, pages 1937-1945.
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