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Cancer Biology & Therapy Volume 15, 2014 - Issue 10
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Research Paper

A novel bisindole-PBD conjugate causes DNA damage induced apoptosis via inhibition of DNA repair pathway

Pranjal Sarma 1 Centre for Chemical Biology; CSIR-Indian Institute of Chemical Technology; Tarnaka, Hyderabad, India; Functional Genomics and Gene Silencing Group; Centre for Cellular and Molecular Biology; Hyderabad, India
,
M Janaki Ramaiah 1 Centre for Chemical Biology; CSIR-Indian Institute of Chemical Technology; Tarnaka, Hyderabad, India
,
Ahmed Kamal Medicinal Chemistry and Pharmacology; CSIR-Indian Institute of Chemical Technology; Tarnaka, Hyderabad, India
,
Utpal Bhadra Functional Genomics and Gene Silencing Group; Centre for Cellular and Molecular Biology; Hyderabad, India
&
Manika Pal Bhadra 1 Centre for Chemical Biology; CSIR-Indian Institute of Chemical Technology; Tarnaka, Hyderabad, IndiaCorrespondence[email protected]
Pages 1320-1332 | Received 10 Jun 2014, Accepted 23 Jun 2014, Published online: 10 Jul 2014

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Pranjal Sarma, Indira Bag, M Janaki Ramaiah, Ahmed Kamal, Utpal Bhadra & Manika Pal Bhadra. (2015) Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis. Cancer Biology & Therapy 16:10, pages 1486-1501.
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Articles from other publishers (4)

Wen Tian, Peng Gao, Da-Peng Zong, Jian-Jun Liu, Meng-Yan Zhang, Cheng-Chen Wang, Zhen-Xing Wang, Jian-Min Wang, You-Ya Niu & Ping Xiang. (2022) The oral bioaccessibility and gingival cytotoxicity of metal(loid)s in wild vegetables from mining areas: Implication for human oral health. Frontiers in Nutrition 9.
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Yue Zhang & Chunhong Hu. (2020) Anticancer activity of bisindole alkaloids derived from natural sources and synthetic bisindole hybrids. Archiv der Pharmazie 353:9, pages 2000092.
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Dongshao Chen, Xiaoting Lin, Jing Gao, Lin Shen, Zhongwu Li, Bin Dong, Cheng Zhang & Xiaotian Zhang. (2018) Wee1 Inhibitor AZD1775 Combined with Cisplatin Potentiates Anticancer Activity against Gastric Cancer by Increasing DNA Damage and Cell Apoptosis. BioMed Research International 2018, pages 1-10.
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Pranjal Sarma, M. Janaki Ramaiah, Dhananjaya Pal, Utpal Bhadra & Manika Pal Bhadra. (2016) A novel bisindole-PBD conjugate inhibits angiogenesis by regulating STAT3 and VEGF in breast cancer cells. Life Sciences 151, pages 264-276.
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