Advanced search
Publication Cover
Cancer Biology & Therapy Volume 4, 2005 - Issue 12
Submit an article Journal homepage
1,049
Views
130
CrossRef citations to date
0
Altmetric
Research Paper

Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors

Mohamed Mokhtar Desouki
,
Mariola Kulawiec
,
Sanjay Bansal
,
Gokul C. Das
&
Keshav K. SinghCorrespondence[email protected]
Pages 1367-1373 | Published online: 18 Oct 2005

Citations (130)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Shashikiran Donthamsetty, Meera Brahmbhatt, Vaishali Pannu, Padmashree Rida, Sujatha Ramarathinam, Angela Ogden, Alice Cheng, Keshav K. Singh & Ritu Aneja. (2014) Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis. Cell Cycle 13:13, pages 2056-2255.
Read now
Mohamad Warda, Hyoung Kyu Kim, Nari Kim, Kyung Soo Ko, Byoung Doo Rhee & Jin Han. (2013) A matter of life, death and diseases: mitochondria from a proteomic perspective. Expert Review of Proteomics 10:1, pages 97-111.
Read now
Gang Cheng, Marcos Lopez, Jacek Zielonka, Andrew D. Hauser, Joy Joseph, Donna McAllister, J. Jordi Rowe, Sonia L. Sugg, Carol L. Williams & Balaraman Kalyanaraman. (2011) Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. Cancer Biology & Therapy 12:8, pages 707-717.
Read now
Kelly A. Graham, Mariola Kulawiec, Kjerstin M. Owens, Xiurong Li, Mohamed M. Desouki, Dhyan Chandra & Keshav K. Singh. (2010) NADPH oxidase 4 is an oncoprotein localized to mitochondria. Cancer Biology & Therapy 10:3, pages 223-231.
Read now
Miroslav Adžić, Ana Nićiforović, Božidarka Zarić, Zora Nešković-Konstantinović, Snežana D. Spasić, David R. Jones & Marija B. Radojčić. (2008) Cell culture conditions potentiate differences in the response to ionising radiation of peripheral blood leukocytes isolated from breast cancer patients and healthy subjects. Redox Report 13:1, pages 17-22.
Read now

Articles from other publishers (125)

Ibolya Czegle, Chelsea Huang, Priscilla Geraldine Soria, Dylan Wesley Purkiss, Andrea Shields & Edina Amalia Wappler-Guzzetta. (2023) The Role of Genetic Mutations in Mitochondrial-Driven Cancer Growth in Selected Tumors: Breast and Gynecological Malignancies. Life 13:4, pages 996.
Crossref
Chao Peng, Xi Li, Feng Ao, Ting Li, Jingpei Guo, Junfeng Liu, Xiaoting Zhang, Jinyan Gu, Junjie Mao & Bin Zhou. (2023) Mitochondrial ROS driven by NOX4 upregulation promotes hepatocellular carcinoma cell survival after incomplete radiofrequency ablation by inducing of mitophagy via Nrf2/PINK1. Journal of Translational Medicine 21:1.
Crossref
Chandrima Gain, Sihyeong Song, Tyler Angtuaco, Sandro Satta & Theodoros Kelesidis. (2023) The role of oxidative stress in the pathogenesis of infections with coronaviruses. Frontiers in Microbiology 13.
Crossref
Mohammad Taghizadieh, Motahareh Seyedi, Sara Azhdari, Fatemeh Dashti, Sayad Mohammad Ali Mirazimi, Hossein Bannazadeh Baghi, Javid Sadri Nahand, Michael Aschner & Hamed Mirzaei. 2023. Gallbladder Cancer. Gallbladder Cancer 3 30 .
Lei Zhu, Yi Zhao, Tongrui Liu, Minglong Chen, Wei Ping Qian, Binghua Jiang, Benjamin G. Barwick, Lumeng Zhang, Toncred M Styblo, Xiaoxian Li & Lily Yang. (2022) Inhibition of NADPH Oxidase-ROS Signal using Hyaluronic Acid Nanoparticles for Overcoming Radioresistance in Cancer Therapy. ACS Nano 16:11, pages 18708-18728.
Crossref
Matthew T. Keeney, Eric K. Hoffman, Kyle Farmer, Christopher R. Bodle, Marco Fazzari, Alevtina Zharikov, Sandra L. Castro, Xiaoping Hu, Amanda Mortimer, Julia K. Kofler, Eugenia Cifuentes-Pagano, Patrick J. Pagano, Edward A. Burton, Teresa G. Hastings, J. Timothy Greenamyre & Roberto Di Maio. (2022) NADPH oxidase 2 activity in Parkinson's disease. Neurobiology of Disease 170, pages 105754.
Crossref
Yao Li, Damir Kračun, Christopher M. DustinMohamed El MassryShuai YuanChristian J. Goossen, Evan R. DeVallanceSanghamitra SahooCynthia St. Hilaire, Aditi U. Gurkar, Toren FinkelAdam C. StraubEugenia Cifuentes-Pagano & Patrick J. Pagano. (2021) Forestalling age-impaired angiogenesis and blood flow by targeting NOX: Interplay of NOX1, IL-6, and SASP in propagating cell senescence. Proceedings of the National Academy of Sciences 118:42.
Crossref
Tomohiko Ishikawa, Takenori Ogawa, Ayako Nakanome, Yasunari Yamauchi, Hajime Usubuchi, Masahiro Shiihara, Takuya Yoshida, Yasunobu Okamura, Kengo Kinoshita, Yukio Katori & Toru Furukawa. (2021) Whole exome sequencing and establishment of an organoid culture of the carcinoma showing thymus-like differentiation (CASTLE) of the parotid gland. Virchows Archiv 478:6, pages 1149-1159.
Crossref
Victor S. Van Laar, Jianming Chen, Alevtina D. Zharikov, Qing Bai, Roberto Di Maio, April A. Dukes, Teresa G. Hastings, Simon C. Watkins, J. Timothy Greenamyre, Claudette M. St Croix & Edward A. Burton. (2020) α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo. Redox Biology 37, pages 101695.
Crossref
Andreas Daiber, Sebastian Steven, Ksenija Vujacic-Mirski, Sanela Kalinovic, Matthias Oelze, Fabio Di Lisa & Thomas Münzel. (2020) Regulation of Vascular Function and Inflammation via Cross Talk of Reactive Oxygen and Nitrogen Species from Mitochondria or NADPH Oxidase—Implications for Diabetes Progression. International Journal of Molecular Sciences 21:10, pages 3405.
Crossref
Maarten P. Rozing, Jon A. Durhuus, Marie Krogh Nielsen, Yousif Subhi, Thomas BL. Kirkwood, Rudi GJ. Westendorp & Torben Lykke Sørensen. (2020) Age-related macular degeneration: A two-level model hypothesis. Progress in Retinal and Eye Research 76, pages 100825.
Crossref
Lixiao Zhang, Xianwei Wang, Ramón Cueto, Comfort Effi, Yuling Zhang, Hongmei Tan, Xuebin Qin, Yong Ji, Xiaofeng Yang & Hong Wang. (2019) Biochemical basis and metabolic interplay of redox regulation. Redox Biology 26, pages 101284.
Crossref
Hugo P. Monteiro, Elaine G. Rodrigues, Adriana K.C. Amorim Reis, Luiz S. LongoJr.Jr., Fernando T. Ogata, Ana I.S. Moretti, Paulo E. da Costa, Ana C.S. Teodoro, Maytê S. Toledo & Arnold Stern. (2019) Nitric oxide and interactions with reactive oxygen species in the development of melanoma, breast, and colon cancer: A redox signaling perspective. Nitric Oxide 89, pages 1-13.
Crossref
Qi-Lin Zhang, Jun Guo, Xian-Yu Deng, Feng Wang, Jun-Yuan Chen & Lian-Bing Lin. (2019) Comparative transcriptomic analysis provides insights into the response to the benzo(a)pyrene stress in aquatic firefly (Luciola leii). Science of The Total Environment 661, pages 226-234.
Crossref
Nirmala Koju, Abdoh Taleb, Jifang Zhou, Ge Lv, Jie Yang, Xian Cao, Hui Lei & Qilong Ding. (2019) Pharmacological strategies to lower crosstalk between nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and mitochondria. Biomedicine & Pharmacotherapy 111, pages 1478-1498.
Crossref
Su Yeon Lee, Min Kyung Ju, Hyun Min Jeon, Yig Ji Lee, Cho Hee Kim, Hye Gyeong Park, Song Iy Han & Ho Sung Kang. (2018) Oncogenic Metabolism Acts as a Prerequisite Step for Induction of Cancer Metastasis and Cancer Stem Cell Phenotype. Oxidative Medicine and Cellular Longevity 2018, pages 1-28.
Crossref
Heera Sharma, Aaron C. Hirko, Michael A. King & Bin Liu. (2018) Role of NADPH oxidase in cooperative reactive oxygen species generation in dopaminergic neurons induced by combined treatment with dieldrin and lindane. Toxicology Letters 299, pages 47-55.
Crossref
Ghassan M. Saed, Robert T. Morris & Nicole M. Fletcher. 2018. Ovarian Cancer - From Pathogenesis to Treatment. Ovarian Cancer - From Pathogenesis to Treatment.
Jennifer N. Moloney & Thomas G. Cotter. (2018) ROS signalling in the biology of cancer. Seminars in Cell & Developmental Biology 80, pages 50-64.
Crossref
Dongya Jia, Jun Park, Kwang Jung, Herbert Levine & Benny Kaipparettu. (2018) Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States. Cells 7:3, pages 21.
Crossref
Peter A. Campochiaro & Tahreem A. Mir. (2018) The mechanism of cone cell death in Retinitis Pigmentosa. Progress in Retinal and Eye Research 62, pages 24-37.
Crossref
Karim Belarbi, Elodie Cuvelier, Alain Destée, Bernard Gressier & Marie-Christine Chartier-Harlin. (2017) NADPH oxidases in Parkinson’s disease: a systematic review. Molecular Neurodegeneration 12:1.
Crossref
Trevor Carden, Bhupendra Singh, Ved Mooga, Prachi Bajpai & Keshav K. Singh. (2017) Epigenetic modification of miR-663 controls mitochondria-to-nucleus retrograde signaling and tumor progression. Journal of Biological Chemistry 292:50, pages 20694-20706.
Crossref
Bhupendra Singh, Josephine S. Modica-Napolitano & Keshav K. Singh. (2017) Defining the momiome: Promiscuous information transfer by mobile mitochondria and the mitochondrial genome. Seminars in Cancer Biology 47, pages 1-17.
Crossref
Aaheli Roy Choudhury & Keshav K. Singh. (2017) Mitochondrial determinants of cancer health disparities. Seminars in Cancer Biology 47, pages 125-146.
Crossref
Chel Hun Choi, Ji-Yoon Ryu, Young-Jae Cho, Hye-Kyung Jeon, Jung-Joo Choi, Kris Ylaya, Yoo-Young Lee, Tae-Joong Kim, Joon-Yong Chung, Stephen M. Hewitt, Byoung-Gie Kim, Duk-Soo Bae & Jeong-Won Lee. (2017) The anti-cancer effects of itraconazole in epithelial ovarian cancer. Scientific Reports 7:1.
Crossref
Andreas Daiber, Fabio Di Lisa, Matthias Oelze, Swenja Kröller-Schön, Sebastian Steven, Eberhard Schulz & Thomas Münzel. (2017) Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function. British Journal of Pharmacology 174:12, pages 1670-1689.
Crossref
A. Cruz-Bermúdez, R. J. Vicente-Blanco, E. Gonzalez-Vioque, M. Provencio, M. Á. Fernández-Moreno & R. Garesse. (2016) Spotlight on the relevance of mtDNA in cancer. Clinical and Translational Oncology 19:4, pages 409-418.
Crossref
Aaron Wilson & Vasily A. Yakovlev. (2016) Cells redox environment modulates BRCA1 expression and DNA homologous recombination repair. Free Radical Biology and Medicine 101, pages 190-201.
Crossref
Kaikai Shen, Fangfang Lu, Jianling Xie, Minfeng Wu, Bo Cai, Yurong Liu, Hong Zhang, Hongsheng Tan, Yingyi Pan & Hongxi Xu. (2016) Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics. Oncotarget 7:31, pages 50596-50611.
Crossref
Lenora Pluchino & Hwa-Chain Wang. 2016. Reactive Oxygen Species in Biology and Human Health. Reactive Oxygen Species in Biology and Human Health 225 241 .
Zhou Xu, Shiling Feng, Shian Shen, Handong Wang, Ming Yuan, Jing Liu, Yan Huang & Chunbang Ding. (2016) The antioxidant activities effect of neutral and acidic polysaccharides from Epimedium acuminatum Franch. on Caenorhabditis elegans. Carbohydrate Polymers 144, pages 122-130.
Crossref
Hezhongrong Nie, Guorong Chen, Jing He, Fengjiao Zhang, Ming Li, Qiufeng Wang, Huaibin Zhou, Jianxin Lyu & Yidong Bai. (2016) Mitochondrial common deletion is elevated in blood of breast cancer patients mediated by oxidative stress. Mitochondrion 26, pages 104-112.
Crossref
Espérance Mukawera, Stefany Chartier, Virginie Williams, Patrick J. Pagano, Réjean Lapointe & Nathalie Grandvaux. (2015) Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines. Redox Biology 6, pages 9-18.
Crossref
Ming Zhan, Hui Wang, Tao Chen, Wei Chen, Linhua Yang, Min He, Sunwang Xu & Jian Wang. (2015) NOX1 mediates chemoresistance via HIF1α/MDR1 pathway in gallbladder cancer. Biochemical and Biophysical Research Communications 468:1-2, pages 79-85.
Crossref
Masami Komiya, Gen Fujii, Shingo Miyamoto, Mami Takahashi, Rikako Ishigamori, Wakana Onuma, Kousuke Ishino, Yukari Totsuka, Kyoko Fujimoto & Michihiro Mutoh. (2015) Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK ‐ A y and Apc mutant Min mice . Cancer Science 106:11, pages 1499-1505.
Crossref
Bhupendra Singh, Kjerstin M. Owens, Prachi Bajpai, Mohamed Mokhtar Desouki, Vinodh Srinivasasainagendra, Hemant K. Tiwari & Keshav K. Singh. (2015) Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties. PLOS ONE 10:10, pages e0139846.
Crossref
Alessandra CastegnaVito Iacobazzi & Vittoria Infantino. (2015) The mitochondrial side of epigenetics. Physiological Genomics 47:8, pages 299-307.
Crossref
Alberto Cruz-Bermúdez, Carmen G. Vallejo, Ramiro J. Vicente-Blanco, María Esther Gallardo, Miguel Ángel Fernández-Moreno, Miguel Quintanilla & Rafael Garesse. (2015) Enhanced tumorigenicity by mitochondrial DNA mild mutations. Oncotarget 6:15, pages 13628-13643.
Crossref
Katharina Bertram, Cristina-Maria Valcu, Michael Weitnauer, Uwe Linne & Agnes Görlach. (2015) NOX1 Supports the Metabolic Remodeling of HepG2 Cells. PLOS ONE 10:3, pages e0122002.
Crossref
Dong-Hee Choi, Ji-Hye Kim, Kyoung-Hee Lee, Hahn-Young Kim, Yoon-Seong Kim, Wahn Soo Choi & Jongmin Lee. (2015) Role of Neuronal NADPH Oxidase 1 in the Peri-Infarct Regions after Stroke. PLOS ONE 10:1, pages e0116814.
Crossref
Igor Afanas’ev. (2015) Mechanisms of Superoxide Signaling in Epigenetic Processes: Relation to Aging and Cancer. Aging and disease 6:3, pages 216.
Crossref
Dong-Hee Choi, Ji-Hye Kim, Joo-Ha Seo, Jongmin Lee, Wahn Soo Choi & Yoon-Seong Kim. (2014) Matrix Metalloproteinase-3 Causes Dopaminergic Neuronal Death through Nox1-Regenerated Oxidative Stress. PLoS ONE 9:12, pages e115954.
Crossref
Daniel T. Shaughnessy, Kimberly McAllister, Leroy Worth, Astrid C. Haugen, Joel N. Meyer, Frederick E. Domann, Bennett Van Houten, Raul Mostoslavsky, Scott J. Bultman, Andrea A. Baccarelli, Thomas J. Begley, Robert W. Sobol, Matthew D. Hirschey, Trey Ideker, Janine H. Santos, William C. Copeland, Raymond R. Tice, David M. Balshaw & Frederick L. Tyson. (2014) Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress. Environmental Health Perspectives 122:12, pages 1271-1278.
Crossref
Philippe Becuwe, Marie Ennen, Rémi Klotz, Claire Barbieux & Stéphanie Grandemange. (2014) Manganese superoxide dismutase in breast cancer: From molecular mechanisms of gene regulation to biological and clinical significance. Free Radical Biology and Medicine 77, pages 139-151.
Crossref
Hengshan Zhang & Keshav K. Singh. (2014) Global Genetic Determinants of Mitochondrial DNA Copy Number. PLoS ONE 9:8, pages e105242.
Crossref
Ian P Harrison & Stavros Selemidis. (2014) Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets. Clinical and Experimental Pharmacology and Physiology 41:8, pages 533-542.
Crossref
Anna KoniorAgata SchrammMarta Czesnikiewicz-GuzikTomasz J. Guzik. (2014) NADPH Oxidases in Vascular Pathology. Antioxidants & Redox Signaling 20:17, pages 2794-2814.
Crossref
Seila Pandur, Chandra Ravuri, Ugo Moens & Nils-Erik Huseby. (2013) Combined incubation of colon carcinoma cells with phorbol ester and mitochondrial uncoupling agents results in synergic elevated reactive oxygen species levels and increased γ-glutamyltransferase expression. Molecular and Cellular Biochemistry 388:1-2, pages 149-156.
Crossref
Shambhunath Choudhary, Shilpa Sood & Hwa-Chain Robert Wang. (2014) Dipyridamole intervention of breast cell carcinogenesis. Molecular Carcinogenesis 53:3, pages 243-252.
Crossref
Chia-Jung Hsieh, Po-Lin Kuo, Ying-Chan Hsu, Ya-Fang Huang, Eing-Mei Tsai & Ya-Ling Hsu. (2014) Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation. Free Radical Biology and Medicine 67, pages 159-170.
Crossref
Eberhard SchulzPhilip WenzelThomas MünzelAndreas Daiber. (2014) Mitochondrial Redox Signaling: Interaction of Mitochondrial Reactive Oxygen Species with Other Sources of Oxidative Stress. Antioxidants & Redox Signaling 20:2, pages 308-324.
Crossref
Apsorn Sattayakhom, Warangkana Chunglok, Wanida Ittarat & Walee Chamulitrat. (2014) Study designs to investigate Nox1 acceleration of neoplastic progression in immortalized human epithelial cells by selection of differentiation resistant cells. Redox Biology 2, pages 140-147.
Crossref
Andy E. Trane & Pascal N. Bernatchez. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants 1537 1554 .
Teresa L. Serafim & Paulo J. Oliveira. 2014. Tumor Metabolome Targeting and Drug Development. Tumor Metabolome Targeting and Drug Development 29 73 .
M.L. Green, M.M. Pisano, R.A. Prough & T.B. Knudsen. (2013) Release of targeted p53 from the mitochondrion as an early signal during mitochondrial dysfunction. Cellular Signalling 25:12, pages 2383-2390.
Crossref
Neelu Yadav & Dhyan Chandra. (2013) Mitochondrial DNA mutations and breast tumorigenesis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1836:2, pages 336-344.
Crossref
Eduardo Cardenas & Rita Ghosh. (2013) Vitamin E: A dark horse at the crossroad of cancer management. Biochemical Pharmacology 86:7, pages 845-852.
Crossref
S. Acharya, A. M. Peters, A. S. Norton, G. K. Murdoch & R. A. Hill. (2013) Change in Nox4 expression is accompanied by changes in myogenic marker expression in differentiating C2C12 myoblasts. Pflügers Archiv - European Journal of Physiology 465:8, pages 1181-1196.
Crossref
Shu-Chen Hung, Chul Hee Choi, Najwane Said-Sadier, Larry Johnson, Kalina Rosenova Atanasova, Hanen Sellami, Özlem Yilmaz & David M. Ojcius. (2013) P2X4 Assembles with P2X7 and Pannexin-1 in Gingival Epithelial Cells and Modulates ATP-induced Reactive Oxygen Species Production and Inflammasome Activation. PLoS ONE 8:7, pages e70210.
Crossref
S Pervin, L Tran, R Urman, M Braga, M Parveen, S A Li, G Chaudhuri & R Singh. (2013) Oxidative stress specifically downregulates survivin to promote breast tumour formation. British Journal of Cancer 108:4, pages 848-858.
Crossref
N B Nataraj, J Krishnamurthy & B P Salimath. (2013) Treatment with anti-NAP monoclonal antibody reduces disease severity in murine model of novel angiogenic protein-induced or ovalbumin-induced arthritis. Clinical and Experimental Immunology 171:2, pages 155-163.
Crossref
Emily I. Chen. (2012) Mitochondrial dysfunction and cancer metastasis. Journal of Bioenergetics and Biomembranes 44:6, pages 619-622.
Crossref
Boel De Paepe. (2012) Mitochondrial Markers for Cancer: Relevance to Diagnosis, Therapy, and Prognosis and General Understanding of Malignant Disease Mechanisms. ISRN Pathology 2012, pages 1-15.
Crossref
Tuuli Kaambre, Vladimir Chekulayev, Igor Shevchuk, Minna Karu-Varikmaa, Natalja Timohhina, Kersti Tepp, Jelena Bogovskaja, Riina Kütner, Vahur Valvere & Valdur Saks. (2012) Metabolic control analysis of cellular respiration in situ in intraoperational samples of human breast cancer. Journal of Bioenergetics and Biomembranes 44:5, pages 539-558.
Crossref
Karen Block & Yves Gorin. (2012) Aiding and abetting roles of NOX oxidases in cellular transformation. Nature Reviews Cancer 12:9, pages 627-637.
Crossref
Stuart G. Jarrett & Michael E. Boulton. (2012) Consequences of oxidative stress in age-related macular degeneration. Molecular Aspects of Medicine 33:4, pages 399-417.
Crossref
Ning Lin, Hanbei Chen, Hongmei Zhang, Xiaoyu Wan & Qing Su. (2012) Mitochondrial reactive oxygen species (ROS) inhibition ameliorates palmitate-induced INS-1 beta cell death. Endocrine 42:1, pages 107-117.
Crossref
N. Lin, H. Zhang & Q. Su. (2012) Advanced glycation end-products induce injury to pancreatic beta cells through oxidative stress. Diabetes & Metabolism 38:3, pages 250-257.
Crossref
Mark RinnerthalerSabrina BüttnerPeter LaunGino HeerenThomas K. FelderHarald KlingerMartin WeinbergerKlaus StolzeTomas Grousl, Jiri Hasek, Oldrich Benada, Ivana Frydlova, Andrea KlockerBirgit Simon-NobbeBettina JanskoHannelore Breitenbach-KollerTobias EisenbergCampbell W. Gourlay, Frank MadeoWilliam C. BurhansMichael Breitenbach. (2012) Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast. Proceedings of the National Academy of Sciences 109:22, pages 8658-8663.
Crossref
Dong-Hee ChoiAna Clara CristóvãoSubhrangshu GuhathakurtaJongmin LeeTong H. JohM. Flint BealYoon-Seong Kim. (2012) NADPH Oxidase 1-Mediated Oxidative Stress Leads to Dopamine Neuron Death in Parkinson's Disease. Antioxidants & Redox Signaling 16:10, pages 1033-1045.
Crossref
Vivian Chen, Richard E. Staub, Sylvia Fong, Mary Tagliaferri, Isaac Cohen & Emma Shtivelman. (2012) Bezielle Selectively Targets Mitochondria of Cancer Cells to Inhibit Glycolysis and OXPHOS. PLoS ONE 7:2, pages e30300.
Crossref
Peter R. Kvietys & D. Neil Granger. (2012) Role of reactive oxygen and nitrogen species in the vascular responses to inflammation. Free Radical Biology and Medicine 52:3, pages 556-592.
Crossref
Yoon Kyung Choi, Elaine D. Por, Young-Guen Kwon & Young-Myeong Kim. (2012) Regulation of ROS Production and Vascular Function by Carbon Monoxide. Oxidative Medicine and Cellular Longevity 2012, pages 1-17.
Crossref
Stuart G. Jarrett, Alfred S. Lewin & Michael E. Boulton. 2012. Studies on Retinal and Choroidal Disorders. Studies on Retinal and Choroidal Disorders 203 239 .
Sergey Dikalov. (2011) Cross talk between mitochondria and NADPH oxidases. Free Radical Biology and Medicine 51:7, pages 1289-1301.
Crossref
Yaw L. Siow, Lindsei Sarna & Karmin O. (2011) Redox regulation in health and disease — Therapeutic potential of berberine. Food Research International 44:8, pages 2409-2417.
Crossref
Vanniarajan Ayyasamy, Kjerstin M. Owens, Mohamed Mokhtar Desouki, Ping Liang, Andrei Bakin, Kumarasamy Thangaraj, Donald J. Buchsbaum, Albert F. LoBuglio & Keshav K. Singh. (2011) Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin. PLoS ONE 6:9, pages e24792.
Crossref
Youxue WangQun S. ZangZijuan LiuQian WuDavid MaassGenevieve DulanPhilip W. ShaulLisa Melito, Doug E. Frantz, Jessica A. Kilgore, Noelle S. Williams, Lance S. Terada & Fiemu E. Nwariaku. (2011) Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species. American Journal of Physiology-Cell Physiology 301:3, pages C695-C704.
Crossref
Kjerstin M. Owens, Mariola Kulawiec, Mohamad Mokhtar Desouki, Ayyasamy Vanniarajan & Keshav K. Singh. (2011) Impaired OXPHOS Complex III in Breast Cancer. PLoS ONE 6:8, pages e23846.
Crossref
David M Krzywanski, Douglas R Moellering, Jessica L Fetterman, Kimberly J Dunham-Snary, Melissa J Sammy & Scott W Ballinger. (2011) The mitochondrial paradigm for cardiovascular disease susceptibility and cellular function: a complementary concept to Mendelian genetics. Laboratory Investigation 91:8, pages 1122-1135.
Crossref
Zhongliang Jiang, Nicole M. Fletcher, Rouba Ali-Fehmi, Michael P. Diamond, Husam M. Abu-Soud, Adnan R. Munkarah & Ghassan M. Saed. (2011) Modulation of redox signaling promotes apoptosis in epithelial ovarian cancer cells. Gynecologic Oncology 122:2, pages 418-423.
Crossref
Han Wei, Dan Wei, Shuo Yi, Fang Zhang Wenjun Ding. (2010) Oxidative stress induced by urban fine particles in cultured EA.hy926 cells. Human & Experimental Toxicology 30:7, pages 579-590.
Crossref
Jennifer Permuth-Wey, Y. Ann Chen, Ya-Yu Tsai, Zhihua Chen, Xiaotao Qu, Johnathan M. Lancaster, Heather Stockwell, Getachew Dagne, Edwin Iversen, Harvey Risch, Jill Barnholtz-Sloan, Julie M. Cunningham, Robert A. Vierkant, Brooke L. Fridley, Rebecca Sutphen, John McLaughlin, Steven A. Narod, Ellen L. Goode, Joellen M. Schildkraut, David Fenstermacher, Catherine M. Phelan & Thomas A. Sellers. (2011) Inherited Variants in Mitochondrial Biogenesis Genes May Influence Epithelial Ovarian Cancer Risk. Cancer Epidemiology, Biomarkers & Prevention 20:6, pages 1131-1145.
Crossref
A Silva, A Gírio, I Cebola, C I Santos, F Antunes & J T Barata. (2011) Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells. Leukemia 25:6, pages 960-967.
Crossref
Dhyan Chandra & Keshav K. Singh. (2011) Genetic insights into OXPHOS defect and its role in cancer. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1807:6, pages 620-625.
Crossref
Rong Wang, Wan-Mohaiza Dashwood, Hui Nian, Christiane V. Löhr, Kay A. Fischer, Naoto Tsuchiya, Hitoshi Nakagama, Hassan Ashktorab & Roderick H. Dashwood. (2011) NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). International Journal of Cancer 128:11, pages 2581-2590.
Crossref
W Michael Zawada, Gregg P Banninger, Jennifer Thornton, Beth Marriott, David Cantu, Angela L Rachubinski, Mita Das, W Sue T Griffin & Susan M Jones. (2011) Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade. Journal of Neuroinflammation 8:1, pages 129.
Crossref
Dora Il’yasova, Kelly Kennedy, Ivan Spasojevic, Frances Wang, Adviye A. Tolun, Karel Base, Sarah P. Young, P. Kelly Marcom, Jeffrey Marks, David S. Millington & Mark W. Dewhirst. (2010) Individual responses to chemotherapy-induced oxidative stress. Breast Cancer Research and Treatment 125:2, pages 583-589.
Crossref
Yang Wang, Shelley X.L. Zhang & David Gozal. (2010) Reactive oxygen species and the brain in sleep apnea. Respiratory Physiology & Neurobiology 174:3, pages 307-316.
Crossref
Jerry A. Saunders, LeAnn C. Rogers, Chananat Klomsiri, Leslie B. Poole & Larry W. Daniel. (2010) Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells. Free Radical Biology and Medicine 49:12, pages 2058-2067.
Crossref
Ekaterina N. PopovaOlga Y. PletjushkinaVera B. DuginaLidia V. DomninaOlga Y. IvanovaDenis S. IzyumovVladimir P. SkulachevBoris V. Chernyak. (2010) Scavenging of Reactive Oxygen Species in Mitochondria Induces Myofibroblast Differentiation. Antioxidants & Redox Signaling 13:9, pages 1297-1307.
Crossref
Jianmin LiHuaqing ZhuE ShenLi WanJ. Malcolm O. ArnoldTianqing Peng. (2010) Deficiency of Rac1 Blocks NADPH Oxidase Activation, Inhibits Endoplasmic Reticulum Stress, and Reduces Myocardial Remodeling in a Mouse Model of Type 1 Diabetes. Diabetes 59:8, pages 2033-2042.
Crossref
Amadou K.S. CamaraEdward J. LesnefskyDavid F. Stowe. (2010) Potential Therapeutic Benefits of Strategies Directed to Mitochondria. Antioxidants & Redox Signaling 13:3, pages 279-347.
Crossref
Mayumi KajimuraRyo FukudaRyon M. BatemanTakehiro YamamotoMakoto Suematsu. (2010) Interactions of Multiple Gas-Transducing Systems: Hallmarks and Uncertainties of CO, NO, and H 2 S Gas Biology . Antioxidants & Redox Signaling 13:2, pages 157-192.
Crossref
Elena A. Ostrakhovitch & Shawn S. C. Li. (2009) NIP1/DUOXA1 expression in epithelial breast cancer cells: regulation of cell adhesion and actin dynamics. Breast Cancer Research and Treatment 119:3, pages 773-786.
Crossref
Isabelle Gorenne & Martin R. Bennett. 2010. Aging and Age-Related Disorders. Aging and Age-Related Disorders 211 235 .
Mariola Kulawiec, Kjerstin M Owens & Keshav K Singh. (2009) mtDNA G10398A variant in African-American women with breast cancer provides resistance to apoptosis and promotes metastasis in mice. Journal of Human Genetics 54:11, pages 647-654.
Crossref
E. ShenYanwen LiYing LiLimei ShanHuaqing ZhuQingping FengJ. Malcolm O. ArnoldTianqing Peng. (2009) Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia. Diabetes 58:10, pages 2386-2395.
Crossref
Ana Clara CristóvãoDong-Hee ChoiGraça BaltazarM. Flint BealYoon-Seong Kim. (2009) The Role of NADPH Oxidase 1–Derived Reactive Oxygen Species in Paraquat-Mediated Dopaminergic Cell Death. Antioxidants & Redox Signaling 11:9, pages 2105-2118.
Crossref
Keshav K Singh, Vanniarajan Ayyasamy, Kjerstin M Owens, Manika Sapru Koul & Marija Vujcic. (2009) Mutations in mitochondrial DNA polymerase-γ promote breast tumorigenesis. Journal of Human Genetics 54:9, pages 516-524.
Crossref
Alicia Guemez-Gamboa & Julio Morán. (2009) NOX2 mediates apoptotic death induced by staurosporine but not by potassium deprivation in cerebellar granule neurons. Journal of Neuroscience Research 87:11, pages 2531-2540.
Crossref
Halley Caixeta Oliveira, Elzira Elisabeth Saviani & Ione Salgado. (2009) NAD(P)H- and superoxide-dependent nitric oxide degradation by rat liver mitochondria. FEBS Letters 583:13, pages 2276-2280.
Crossref
Igor Afanas'ev. 2009. Signaling Mechanisms of Oxygen and Nitrogen Free Radicals. Signaling Mechanisms of Oxygen and Nitrogen Free Radicals 5 54 .
João WosniakJr.Jr., Célio X. C. SantosAlicia J. KowaltowskiFrancisco R. M. Laurindo. (2009) Cross-Talk Between Mitochondria and NADPH Oxidase: Effects of Mild Mitochondrial Dysfunction on Angiotensin II-Mediated Increase in Nox Isoform Expression and Activity in Vascular Smooth Muscle Cells. Antioxidants & Redox Signaling 11:6, pages 1265-1278.
Crossref
Keshav K. Singh & Mariola Kulawiec. 2009. Cancer Epidemiology. Cancer Epidemiology 291 303 .
Kjerstin M. Owens, J. S. Modica-Napolitano & Keshav K. Singh. 2009. Mitochondria and Cancer. Mitochondria and Cancer 1 21 .
João Jr Wosniak, Celio X.C. Santos, Alícia Juliana Kowaltowski & Francisco Laurindo. (2008) Cross-talk between mitochondria and NADPH oxidase: Effects of mild mitochondrial dysfunction on angiotensin II mediated increase in Nox isoform expression and activity in vascular smooth muscle cells. Antioxidants & Redox Signaling, pages 110306091003087.
Crossref
Angélica Coyoy, Antonio Valencia, Alicia Guemez-Gamboa & Julio Morán. (2008) Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons. Free Radical Biology and Medicine 45:8, pages 1056-1064.
Crossref
Miryam Calvino-Fernández, Selma Benito-Martínez & Trinidad Parra-Cid. (2008) Oxidative stress by Helicobacter pylori causes apoptosis through mitochondrial pathway in gastric epithelial cells. Apoptosis 13:10, pages 1267-1280.
Crossref
Smita S. Matkar, Lisa A. Wrischnik & Utha Hellmann-Blumberg. (2008) Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis. Archives of Biochemistry and Biophysics 477:1, pages 43-52.
Crossref
Masuko Ushio-Fukai & Yoshimasa Nakamura. (2008) Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy. Cancer Letters 266:1, pages 37-52.
Crossref
Mohamad Warda & Jin Han. (2008) Retracted: Mitochondria, the missing link between body and soul: Proteomic prospective evidence. PROTEOMICS 8:3, pages I-XXIII.
Crossref
Jorge D. ErusalimskySalvador Moncada. (2007) Nitric Oxide and Mitochondrial Signaling. Arteriosclerosis, Thrombosis, and Vascular Biology 27:12, pages 2524-2531.
Crossref
Mathieu DesmardJorge BoczkowskiJuan PoderosoRoberto Motterlini. (2007) Mitochondrial and Cellular Heme-Dependent Proteins as Targets for the Bioactive Function of the Heme Oxygenase/Carbon Monoxide System. Antioxidants & Redox Signaling 9:12, pages 2139-2156.
Crossref
Linda A. Tephly & A. Brent Carter. (2007) Constitutive NADPH oxidase and increased mitochondrial respiratory chain activity regulate chemokine gene expression. American Journal of Physiology-Lung Cellular and Molecular Physiology 293:5, pages L1143-L1155.
Crossref
María P. Pérez de Obanos, María J. López-Zabalza, Elena Arriazu, Teresa Modol, Jesús Prieto, María T. Herraiz & María J. Iraburu. (2007) Reactive oxygen species (ROS) mediate the effects of leucine on translation regulation and type I collagen production in hepatic stellate cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773:11, pages 1681-1688.
Crossref
Julian D. WidderTomasz J. GuzikCornelius F.H. MuellerRoza E. ClempusHarald H.H.W. SchmidtSergey I. DikalovKathy K. GriendlingDean P. JonesDavid G. Harrison. (2007) Role of the Multidrug Resistance Protein-1 in Hypertension and Vascular Dysfunction Caused by Angiotensin II. Arteriosclerosis, Thrombosis, and Vascular Biology 27:4, pages 762-768.
Crossref
Karl-Heinz Krause. (2007) Aging: A revisited theory based on free radicals generated by NOX family NADPH oxidases. Experimental Gerontology 42:4, pages 256-262.
Crossref
Haifeng Zhang, Yan Luo, Wei Zhang, Yun He, Shengchuan Dai, Rong Zhang, Yan Huang, Pascal Bernatchez, Frank J. Giordano, Gerald Shadel, William C. Sessa & Wang Min. (2007) Endothelial-Specific Expression of Mitochondrial Thioredoxin Improves Endothelial Cell Function and Reduces Atherosclerotic Lesions. The American Journal of Pathology 170:3, pages 1108-1120.
Crossref
Jorge Boczkowski, Juan J. Poderoso & Roberto Motterlini. (2006) CO–metal interaction: vital signaling from a lethal gas. Trends in Biochemical Sciences 31:11, pages 614-621.
Crossref
Jessica GutierrezScott W. BallingerVictor M. Darley-UsmarAimee Landar. (2006) Free Radicals, Mitochondria, and Oxidized Lipids. Circulation Research 99:9, pages 924-932.
Crossref
Stephanie Carnesecchi, Jean-Louis Carpentier, Michelangelo Foti & Ildiko Szanto. (2006) Insulin-induced vascular endothelial growth factor expression is mediated by the NADPH oxidase NOX3. Experimental Cell Research 312:17, pages 3413-3424.
Crossref
Maria Carolina GongoraZhenyu QinKarine LaudeHa Won KimLouise McCannJ. Rodney FolzSergey DikalovTohru FukaiDavid G. Harrison. (2006) Role of Extracellular Superoxide Dismutase in Hypertension. Hypertension 48:3, pages 473-481.
Crossref
Kazuhito RokutanTsukasa KawaharaYuki KuwanoKumiko TominagaAtsuo SekiyamaShigetada Teshima-Kondo. (2006) NADPH Oxidases in the Gastrointestinal Tract: A Potential Role of Nox1 in Innate Immune Response and Carcinogenesis. Antioxidants & Redox Signaling 8:9-10, pages 1573-1582.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.