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Research Paper

Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors

Pages 773-780 | Published online: 25 May 2005

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Thomas Mikeska, Christoph Bock, Hongdo Do & Alexander Dobrovic. (2012) DNA methylation biomarkers in cancer: progress towards clinical implementation. Expert Review of Molecular Diagnostics 12:5, pages 473-487.
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Articles from other publishers (30)

Keizo Kato. 2022. Inflammation and Oral Cancer. Inflammation and Oral Cancer 79 100 .
Andrea E. Wahner Hendrickson, Daniel W. Visscher, Xiaonan Hou, Krista M. Goergen, Hunter J. Atkinson, Thomas G. Beito, Vivian Negron, Wilma L. Lingle, Amy K. Bruzek, Rachel M. Hurley, Jill M. Wagner, Karen S. Flatten, Kevin L. Peterson, Paula A. Schneider, Melissa C. Larson, Matthew J. Maurer, Kimberly R. Kalli, Ann L. Oberg, S. John Weroha & Scott H. Kaufmann. (2021) CHFR and Paclitaxel Sensitivity of Ovarian Cancer. Cancers 13:23, pages 6043.
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Chao Wu, Zuowei Wu & Bole Tian. (2020) Five gene signatures were identified in the prediction of overall survival in resectable pancreatic cancer. BMC Surgery 20:1.
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Yongjun Cha, Sun Young Kim, Hyun Yang Yeo, Ji Yeon Baek, Moon Ki Choi, Kyung Hae Jung, Seung Myung Dong & Hee Jin Chang. (2019) Association of CHFR Promoter Methylation with Treatment Outcomes of Irinotecan-Based Chemotherapy in Metastatic Colorectal Cancer. Neoplasia 21:1, pages 146-155.
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Di Zhang, Xiao‑Lan Xu, Fei Li, Hai‑Chen Sun, Ye‑Qing Cui, Shuang Liu & Ping‑Yong Xu. (2017) Upregulation of the checkpoint protein CHFR is associated with tumor suppression in pancreatic cancers. Oncology Letters.
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Tianyang Yun, Yang Liu, Dan Gao, Enqiang Linghu, Malcolm V. Brock, Dongtao Yin, Qimin Zhan, James G. Herman & Mingzhou Guo. (2014) Methylation of CHFR sensitizes esophageal squamous cell cancer to docetaxel and paclitaxel. Genes & Cancer 6:1-2, pages 38-48.
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Xi Chen, Jianjun Shen, Xingyu Li, Xi Wang, Min Long, Fang Lin, Junxia Wei, Longfei Yang, Chinglai Yang, Ke Dong & Huizhong Zhang. (2014) Rlim, an E3 ubiquitin ligase, influences the stability of Stathmin protein in human osteosarcoma cells. Cellular Signalling 26:7, pages 1532-1538.
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Arjen H.G. Cleven, Sarah Derks, Muriel X.G. Draht, Kim M. Smits, Veerle Melotte, Leander Van Neste, Benjamin Tournier, Valerie Jooste, Caroline Chapusot, Matty P. Weijenberg, James G. Herman, Adriaan P. de Bruïne & Manon van Engeland. (2014) CHFR Promoter Methylation Indicates Poor Prognosis in Stage II Microsatellite Stable Colorectal Cancer . Clinical Cancer Research 20:12, pages 3261-3271.
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Lorraine Pelosof, Sashidhar R. Yerram, Nita Ahuja, Andrew Delmas, Ludmila Danilova, James G. Herman & Nilofer S. Azad. (2014) CHFR silencing or microsatellite instability is associated with increased antitumor activity of docetaxel or gemcitabine in colorectal cancer . International Journal of Cancer 134:3, pages 596-605.
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Sarah Derks, Arjen H. G. Cleven, Veerle Melotte, Kim M. Smits, Johann C. Brandes, Nilofer Azad, Wim van Criekinge, Adriaan P. de Bruïne, James G. Herman & Manon van Engeland. (2013) Emerging evidence for CHFR as a cancer biomarker: from tumor biology to precision medicine. Cancer and Metastasis Reviews.
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Rathi N. Pillai, Seth A. Brodie, Gabriel L. Sica, You Shaojin, Ge Li, Dana C. Nickleach, Liu Yuan, Vijay A. Varma, Dacian Bonta, James G. Herman, Malcom V. Brock, Maria J.A. Ribeiro, Suresh S. Ramalingam, Taofeek K. Owonikoko, Fadlo R. Khuri & Johann C. Brandes. (2013) CHFR Protein Expression Predicts Outcomes to Taxane-Based First Line Therapy in Metastatic NSCLC. Clinical Cancer Research 19:6, pages 1603-1611.
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Sheru Sanbhnani & Foong May Yeong. (2011) CHFR: a key checkpoint component implicated in a wide range of cancers. Cellular and Molecular Life Sciences 69:10, pages 1669-1687.
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Kouji BannoIori Kisu, Megumi Yanokura, Kenta Masuda, Arisa Ueki, Yusuke Kobayashi, Nobuyuki Susumu & Daisuke Aoki. (2012) Epigenetics and genetics in endometrial cancer: new carcinogenic mechanisms and relationship with clinical practice. Epigenomics 4:2, pages 147-162.
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Lisa Kashima, Masashi Idogawa, Hiroaki Mita, Miki Shitashige, Tesshi Yamada, Kazuhiro Ogi, Hiromu Suzuki, Minoru Toyota, Hiroyoshi Ariga, Yasushi Sasaki & Takashi Tokino. (2012) CHFR Protein Regulates Mitotic Checkpoint by Targeting PARP-1 Protein for Ubiquitination and Degradation. Journal of Biological Chemistry 287:16, pages 12975-12984.
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Aya Fujita, Hidetaka Yamamoto, Masakazu Imamura, Norimoto Nakamura, Yoshihiko Maehara, Masazumi Tsuneyoshi & Yoshinao Oda. (2011) Expression level of the mitotic checkpoint protein and G2?M cell cycle regulators and prognosis in gastrointestinal stromal tumors in the stomach. Virchows Archiv 460:2, pages 163-169.
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Kenta Masuda, Kouji Banno, Megumi Yanokura, Kosuke Tsuji, Iori Kisu, Arisa Ueki, Yusuke Kobayashi, Hiroyuki Nomura, Akira Hirasawa, Nobuyuki Susumu & Daisuke Aoki. 2012. Epigenetics in Human Disease. Epigenetics in Human Disease 471 480 .
Xiaoyun Wang, Yuebo Yang, Chengfang Xu, Lan Xiao, Huimin Shen, Xu Zhang, Tian Li & Xiaomao Li. (2011) CHFR Suppression by Hypermethylation Sensitizes Endometrial Cancer Cells to Paclitaxel. International Journal of Gynecological Cancer 21:6, pages 996-1003.
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Asuka Ono, Iori Kisu, Kouji Banno, Megumi Yanokura, Kenta Masuda, Yusuke Kobayashi, Kosuke Tsuji, Arisa Ueki, Wataru Yamagami, Hiroyuki Nomura, Nobuyuki Susumu & Daisuke Aoki. (2011) Epigenetic Aberrant Hypermethylation of DNA in Endometrial Cancer: Application as a Biomarker. Journal of Cancer Therapy 02:05, pages 610-615.
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Verónica Dávalos & Manel Esteller. 2010. Medicina Personalizada Posgenómica. Conceptos Prácticos Para Clínicos. Medicina Personalizada Posgenómica. Conceptos Prácticos Para Clínicos 301 320 .
Minoru Toyota & Hiromu Suzuki. 2010. Epigenetics and Cancer, Part A. Epigenetics and Cancer, Part A 309 323 .
L Kashima, M Toyota, H Mita, H Suzuki, M Idogawa, K Ogi, Y Sasaki & T Tokino. (2009) CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-κB. Oncogene 28:29, pages 2643-2653.
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Minoru Toyota, Hiromu Suzuki, Toshiharu Yamashita, Koichi Hirata, Kohzoh Imai, Takashi Tokino & Yasuhisa Shinomura. (2009) Cancer epigenomics: Implications of DNA methylation in personalized cancer therapy. Cancer Science 100:5, pages 787-791.
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Hiromu SuzukiTakashi Tokino, Yasuhisa Shinomura, Kohzoh Imai & Minoru Toyota. (2008) DNA methylation and cancer pathways in gastrointestinal tumors. Pharmacogenomics 9:12, pages 1917-1928.
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Lisa M. Privette & Elizabeth M. Petty. (2008) CHFR: A Novel Mitotic Checkpoint Protein and Regulator of Tumorigenesis. Translational Oncology 1:2, pages 57-64.
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Lisa M. Privette, Jingly Fung Weier, Ha Nam Nguyen, Xiaochun Yu & Elizabeth M. Petty. (2008) Loss of CHFR in Human Mammary Epithelial Cells Causes Genomic Instability by Disrupting the Mitotic Spindle Assembly Checkpoint. Neoplasia 10:7, pages 643-652.
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Takashi Imai, Minoru Toyota, Hiromu Suzuki, Kimishige Akino, Kazuhiro Ogi, Yohei Sogabe, Lisa Kashima, Reo Maruyama, Masanori Nojima, Hiroaki Mita, Yasushi Sasaki, Fumio Itoh, Kohzoh Imai, Yasuhisa Shinomura, Hiroyoshi Hiratsuka & Takashi Tokino. (2008) Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma. Cancer Science 99:5, pages 958-966.
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Tomokazu Fukuda, Yasuyuki Kondo & Hitoshi Nakagama. (2008) The Anti-Proliferative Effects of the CHFR Depend on the Forkhead Associated Domain, but not E3 Ligase Activity Mediated by Ring Finger Domain. PLoS ONE 3:3, pages e1776.
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Minoru Toyota, Lisa Kashima & Takashi Tokino. 2008. Checkpoint Responses in Cancer Therapy. Checkpoint Responses in Cancer Therapy 163 176 .
Lisa M. Privette, Maria E. González, Lei Ding, Celina G. Kleer & Elizabeth M. Petty. (2007) Altered Expression of the Early Mitotic Checkpoint Protein, CHFR, in Breast Cancers: Implications for Tumor Suppression. Cancer Research 67:13, pages 6064-6074.
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Rafael RosellMariacarmela SantarpiaTeresa MoranMaria Fernanda Salazar, Diego Lucas KaenJose Luis Ramirez. (2007) Age-related genetic abnormalities: the Achilles’ heel for customizing therapy in elderly lung cancer patients. Personalized Medicine 4:1, pages 59-72.
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