318
Views
17
CrossRef citations to date
0
Altmetric
Research Paper

Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity

Pages 1726-1731 | Published online: 01 Nov 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Jian-Ming Feng, Ze-Hong Miao, Yi Jiang, Yi Chen, Jia-Xin Li, Lin-Jiang Tong, Jin Zhang, Yi-Ran Huang & Jian Ding. (2012) Characterization of the conversion between CD133+ and CD133- cells in colon cancer SW620 cell line. Cancer Biology & Therapy 13:14, pages 1396-1406.
Read now
Zakir Ullah, Christelle de Renty & Melvin L. DePamphilis. (2011) Checkpoint Kinase 1 Prevents Cell Cycle Exit Linked to Terminal Cell Differentiation. Molecular and Cellular Biology 31:19, pages 4129-4143.
Read now

Articles from other publishers (15)

Osheen Sahay, Ganesh Kumar Barik, Tanisha Sharma, Ajay D. Pillai, Srikanth Rapole & Manas Kumar Santra. (2022) Damsel in distress calling on her knights: Illuminating the pioneering role of E3 ubiquitin ligases in guarding the genome integrity. DNA Repair 109, pages 103261.
Crossref
Niko Moses, Mu Zhang, Jheng-Yu Wu, Chen Hu, Shengyan Xiang, Xinran Geng, Yue Chen, Wenlong Bai, You-Wei Zhang, Gerold Bepler & Xiaohong Mary Zhang. (2020) HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1. Cells 9:10, pages 2237.
Crossref
Baki Akgül, Matthias Kirschberg, Alan Storey & Martin Hufbauer. (2019) Human papillomavirus type 8 oncoproteins E6 and E7 cooperate in downregulation of the cellular checkpoint kinase-1. International Journal of Cancer 145:3, pages 797-806.
Crossref
Qian-Ting Tian, Chun-Yong Ding, Shan-Shan Song, Ying-Qing Wang, Ao Zhang & Ze-Hong Miao. (2018) New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis. Biochemical Pharmacology 154, pages 255-264.
Crossref
Yingfeng Tu, Hongmei Liu, Xuefei Zhu, Hongyan Shen, Xiaolu Ma, Fengli Wang, Min Huang, Juanjuan Gong, Xiaoling Li, Yun Wang, Caixia Guo & Tie-Shan Tang. (2017) Ataxin-3 promotes genome integrity by stabilizing Chk1. Nucleic Acids Research 45:8, pages 4532-4549.
Crossref
Xiujuan Jiang, Juan Wang, Lingxiao Xing, Haitao Shen, Weiguang Lian, Li Yi, Donghui Zhang, Haiyan Yang, Jianghui Liu & Xianghong Zhang. (2016) Sterigmatocystin-induced checkpoint adaptation depends on Chk1 in immortalized human gastric epithelial cells in vitro. Archives of Toxicology 91:1, pages 259-270.
Crossref
Emma Y. Liu, Naihan Xu, Jim O’Prey, Laurence Y. Lao, Sanket Joshi, Jaclyn S. Long, Margaret O’Prey, Daniel R. Croft, Florian Beaumatin, Alice D. Baudot, Michaela Mrschtik, Mathias Rosenfeldt, Yaou Zhang, David A. Gillespie & Kevin M. Ryan. (2015) Loss of autophagy causes a synthetic lethal deficiency in DNA repair. Proceedings of the National Academy of Sciences 112:3, pages 773-778.
Crossref
Mayumi Kaneko, Daisuke Matsuda, Masaki Ohtawa, Takashi Fukuda, Tohru Nagamitsu, Takao Yamori & Hiroshi Tomoda. (2012) Potentiation of Bleomycin in Jurkat Cells by Fungal Pycnidione. Biological and Pharmaceutical Bulletin 35:1, pages 18-28.
Crossref
Bin Xu, Jian Ding, Kai-Xian Chen, Ze-Hong Miao, He Huang, Hong Liu & Xiao-Min Luo. 2012. Recent Advances in Cancer Research and Therapy. Recent Advances in Cancer Research and Therapy 287 350 .
Yu-Qin Wang, Xiao-Hua Li, Qian He, Yi Chen, Yu-Yuan Xie, Jian Ding, Ze-Hong Miao & Chun-Hao Yang. (2011) Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents. European Journal of Medicinal Chemistry 46:12, pages 5878-5884.
Crossref
Ae Jeong Kim, Hyun-Ju Kim, Hye Jin Jee, Naree Song, Minjee Kim, Yoe-Sik Bae, Jay H. Chung & Jeanho Yun. (2011) Glucose deprivation is associated with Chk1 degradation through the ubiquitin–proteasome pathway and effective checkpoint response to replication blocks. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813:6, pages 1230-1238.
Crossref
William Brazelle, Jenny M. Kreahling, Jennifer Gemmer, Yihong Ma, W. Douglas Cress, Eric Haura & Soner Altiok. (2010) Histone Deacetylase Inhibitors Downregulate Checkpoint Kinase 1 Expression to Induce Cell Death in Non-Small Cell Lung Cancer Cells. PLoS ONE 5:12, pages e14335.
Crossref
Zhao-Li Zhou, Zhi-Guo Luo, Bing Yu, Yi Jiang, Yi Chen, Jian-Ming Feng, Mei Dai, Lin-Jiang Tong, Zheng Li, Yuan-Chao Li, Jian Ding & Ze-Hong Miao. (2010) Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide. Molecular Cancer 9:1.
Crossref
Hong Zhu, Ze-Hong Miao, Min Huang, Jian-Ming Feng, Zhi-Xiang Zhang, Jin-Jian Lu, Yu-Jun Cai, Lin-Jiang Tong, Yu-Fang Xu, Xu-Hong Qian & Jian Ding. (2009) Naphthalimides Induce G2 Arrest Through the ATM-Activated Chk2-Executed Pathway in HCT116 Cells. Neoplasia 11:11, pages 1226-1234.
Crossref
You-Wei Zhang, John Brognard, Chris Coughlin, Zhongsheng You, Marisa Dolled-Filhart, Aaron Aslanian, Gerard Manning, Robert T. Abraham & Tony Hunter. (2009) The F Box Protein Fbx6 Regulates Chk1 Stability and Cellular Sensitivity to Replication Stress. Molecular Cell 35:4, pages 442-453.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.