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Research Paper

Concomitant activation of the JAK/STAT3 and ERK1/2 signaling is involved in leptin-mediated proliferation of renal cell carcinoma Caki-2 cells

Pages 1787-1792 | Published online: 01 Nov 2008

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Xue Wang, Yu Ren, Haihui Zhuang, Xiangyu Meng, Shuaishuai Huang, Yanyuan Li, Michael Hehir & Ping Wang. (2015) Decrease of phosphorylated proto-oncogene at Ser 133 site inhibits growth and metastatic activity of renal cell cancer. Expert Opinion on Therapeutic Targets 19:7, pages 985-995.
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Nan Jiang, Rongtong Sun & Qing Sun. (2014) Leptin signaling molecular actions and drug target in hepatocellular carcinoma. Drug Design, Development and Therapy 8, pages 2295-2302.
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Wen-Yong Wu, Hyunchul Kim, Chang-Le Zhang, Xiang-Ling Meng & Zheng-Sheng Wu. (2014) Loss of Suppressors of Cytokine Signaling 3 Promotes Aggressiveness in Hepatocellular Carcinoma. Journal of Investigative Surgery 27:4, pages 197-204.
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Weiqiang Zhou, Yuwang Tian, Hangjun Gong, Shanchun Guo & Chengyu Luo. (2014) Oncogenic role and therapeutic target of leptin signaling in colorectal cancer. Expert Opinion on Therapeutic Targets 18:8, pages 961-971.
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Asma Gati, Soumaya Kouidhi, Raja Marrakchi, Amel El Gaaied, Nadia Kourda, Amine Derouiche, Mohamed Chebil, Anne Caignard & Aurélie Perier. (2014) Obesity and renal cancer. OncoImmunology 3:1.
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Brent J. Tierney, Georgia A. McCann, David E. Cohn, Eric Eisenhauer, Meryl Sudhakar, Periannan Kuppusamy, Kálmán Hideg & Karuppaiyah Selvendiran. (2012) HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells. Cancer Biology & Therapy 13:9, pages 766-775.
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Yucheng Ma, Zhongyu Jian, Liyuan Xiang & Xi Jin. (2022) Higher genetically predicted low‐density lipoprotein levels increase the renal cancer risk independent of triglycerides and high‐density lipoprotein levels: A Mendelian randomization study. International Journal of Cancer 151:4, pages 518-525.
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Anna Gluba-Brzózka, Jacek Rysz, Janusz Ławiński & Beata Franczyk. (2022) Renal Cell Cancer and Obesity. International Journal of Molecular Sciences 23:6, pages 3404.
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Komathi Perumal, Weng Kit Huin, Ning Yi Yap, Teng Aik Ong, Glenda Carolyn Gobe & Retnagowri Rajandram. (2019) Role of leptin as a biomarker for early detection of renal cell carcinoma? No evidence from a systematic review and meta-analysis. Medical Hypotheses 129, pages 109239.
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Xuetao Yan, Xiaoli Cheng, Xianghu He, Wenzhong Zheng, Xiaofang Yuan & Hu Chen. (2018) HO-1 Overexpressed Mesenchymal Stem Cells Ameliorate Sepsis-Associated Acute Kidney Injury by Activating JAK/stat3 Pathway. Cellular and Molecular Bioengineering 11:6, pages 509-518.
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K.L. Ng, S.J. Del Vecchio, H. Samaratunga, C. Morais, R. Rajandram, D.A. Vesey, S.T. Wood & G.C. Gobe. (2018) Leptin and its receptor: can they help to differentiate chromophobe renal cell carcinoma from renal oncocytoma?. Pathology 50:5, pages 504-510.
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Margot P. Cleary & Marta Torroella-Kouri. 2017. Adipocytokines, Energy Balance, and Cancer. Adipocytokines, Energy Balance, and Cancer 39 65 .
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Guiming Zhang, Chengyuan Gu, Yao Zhu, Lei Luo, Dahai Dong, Fangning Wan, Hailiang Zhang, Guohai Shi, Lijiang Sun & Dingwei Ye. (2015) ADIPOQ polymorphism rs182052 is associated with clear cell renal cell carcinoma . Cancer Science 106:6, pages 687-691.
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Gui-Ming Zhang, Yao Zhu & Ding-Wei Ye. (2014) Metabolic syndrome and renal cell carcinoma. World Journal of Surgical Oncology 12:1.
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Hui-Jun Mu, Jian Zou, Ping Xie, Zhuo-Qun Xu, Jun Ruan, Shu-Dong Yang & Ying Yin. (2014) Association of Leptin Receptor Lys109Arg and Gln223Arg Polymorphisms with Increased Risk of Clear Cell Renal Cell Carcinoma. Asian Pacific Journal of Cancer Prevention 15:10, pages 4211-4215.
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Mehdi Hedayati, Parichehr Yaghmaei, Zahra Pooyamanesh, Marjan Zarif Yeganeh & Laleh Hoghooghi Rad. (2011) Leptin: A Correlated Peptide to Papillary Thyroid Carcinoma?. Journal of Thyroid Research 2011, pages 1-5.
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Kin Tak Chan, Kwan Li, Shiu Lam Liu, Kee Hung Chu, Melvin Toh & Wei Dong Xie. (2010) Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562. Cancer Letters 289:1, pages 46-52.
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