991
Views
86
CrossRef citations to date
0
Altmetric
Review

Modulation of death receptors by cancer therapeutic agents

Pages 163-173 | Published online: 04 Feb 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Nesma A. Abd Elrazik, Mohamed El-Mesery, Amro El-Karef, Laila A. Eissa & Amal M El Gayar. (2022) Sesamol Upregulates Death Receptors and Acts as a Chemosensitizer in Solid Ehrlich Carcinoma Model in Mice. Nutrition and Cancer 74:1, pages 250-264.
Read now
Satoshi Yano, Shusong Wu, Kozue Sakao & De-Xing Hou. (2019) Involvement of ERK1/2-mediated ELK1/CHOP/DR5 pathway in 6-(methylsulfinyl)hexyl isothiocyanate-induced apoptosis of colorectal cancer cells. Bioscience, Biotechnology, and Biochemistry 83:5, pages 960-969.
Read now
VG Minero, D De Stefanis, P Costelli, FM Baccino & G Bonelli. (2015) In vitro and in vivo conditional sensitization of hepatocellular carcinoma cells to TNF-induced apoptosis by Taxol. Cell Cycle 14:7, pages 1090-1102.
Read now
Norma Lynn Fox, Robin Humphreys, Troy A Luster, Jerry Klein & Gilles Gallant. (2010) Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-1 and receptor-2 agonists for cancer therapy. Expert Opinion on Biological Therapy 10:1, pages 1-18.
Read now

Articles from other publishers (82)

Kellsye P. Fabian, Joshua T. Kowalczyk, Sandy T. Reynolds & James W. Hodge. (2022) Dying of Stress: Chemotherapy, Radiotherapy, and Small-Molecule Inhibitors in Immunogenic Cell Death and Immunogenic Modulation. Cells 11:23, pages 3826.
Crossref
Gul-e-Saba Chaudhry, Abdah Md Akim, Yeong Yik Sung & Tengku Sifzizul Tengku Muhammad. 2022. Apoptosis and Cancer. Apoptosis and Cancer 191 210 .
Jean Lemoine, Marco Ruella & Roch Houot. (2021) Overcoming Intrinsic Resistance of Cancer Cells to CAR T-Cell Killing. Clinical Cancer Research 27:23, pages 6298-6306.
Crossref
Kellsye P. Fabian, Benjamin Wolfson & James W. Hodge. (2021) From Immunogenic Cell Death to Immunogenic Modulation: Select Chemotherapy Regimens Induce a Spectrum of Immune-Enhancing Activities in the Tumor Microenvironment. Frontiers in Oncology 11.
Crossref
Ming-Chang HsiehYu-Sheng LoYi-Ching ChuangChia-Chieh LinHsin-Yu HoMing-Ju HsiehJen-Tsun Lin. (2021) Dehydrocrenatidine extracted from Picrasma quassioides induces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways . Oncology Reports 46:2.
Crossref
You-Take Oh & Shi-Yong Sun. (2021) Regulation of Cancer Metastasis by TRAIL/Death Receptor Signaling. Biomolecules 11:4, pages 499.
Crossref
Mamta Kumari, Praveen T. Krishnamurthy, Sai kiran S. S. PinduproluPiyongsola Sola. (2020) DR-5 and DLL-4 mAb Functionalized SLNs of Gamma-Secretase Inhibitors- An Approach for TNBC Treatment. Advanced Pharmaceutical Bulletin 11:4, pages 618-623.
Crossref
Yuko Kojima, Takashi Nishina, Hiroyasu Nakano, Ko Okumura & Kazuyoshi Takeda. (2020) Inhibition of Importin β1 Augments the Anticancer Effect of Agonistic Anti-Death Receptor 5 Antibody in TRAIL-resistant Tumor Cells. Molecular Cancer Therapeutics 19:5, pages 1123-1133.
Crossref
Artem A. Artykov, Dmitry A. Belov, Victoria O. Shipunova, Daria B. Trushina, Sergey M. Deyev, Dmitry A. Dolgikh, Mikhail P. Kirpichnikov & Marine E. Gasparian. (2020) Chemotherapeutic Agents Sensitize Resistant Cancer Cells to the DR5-Specific Variant DR5-B More Efficiently Than to TRAIL by Modulating the Surface Expression of Death and Decoy Receptors. Cancers 12:5, pages 1129.
Crossref
Shao-Min He, Yu-Hua Lei, Jian-Min Wang, Li-Na Geng, Shu-Ping Wang, Juan Zhao & Yi-Fang Hou. (2020) The protective effect of nitronyl nitroxide radical on peroxidation of A549 cell damaged by iron overload. Materials Science and Engineering: C 108, pages 110189.
Crossref
Giovanna C. Cavalcante, Ana Paula Schaan, Gleyce Fonseca Cabral, Mayara Natália Santana-da-Silva, Pablo Pinto, Amanda F. Vidal & Ândrea Ribeiro-dos-Santos. (2019) A Cell’s Fate: An Overview of the Molecular Biology and Genetics of Apoptosis. International Journal of Molecular Sciences 20:17, pages 4133.
Crossref
Rehmat Jan & Gul-e-Saba Chaudhry. (2019) Understanding Apoptosis and Apoptotic Pathways Targeted Cancer Therapeutics. Advanced Pharmaceutical Bulletin 9:2, pages 205-218.
Crossref
Andrew M. Gravett, Angus G. Dalgleish & John Copier. (2019) In vitro culture with gemcitabine augments death receptor and NKG2D ligand expression on tumour cells. Scientific Reports 9:1.
Crossref
Ha-Na Oh, Keon Bong Oh, Mee-Hyun Lee, Ji-Hye Seo, Eunae Kim, Goo Yoon, Seung-Sik Cho, Young Sik Cho, Hyun Woo Choi, Jung-II Chae & Jung-Hyun Shim. (2019) JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma. Phytomedicine 52, pages 60-69.
Crossref
Martin Siegemund, Felix Schneider, Meike Hutt, Oliver Seifert, Ines Müller, Dagmar Kulms, Klaus Pfizenmaier & Roland E. Kontermann. (2018) IgG-single-chain TRAIL fusion proteins for tumour therapy. Scientific Reports 8:1.
Crossref
You-Take Oh, Ping Yue & Shi-Yong Sun. (2017) DR5 suppression induces sphingosine-1-phosphate-dependent TRAF2 polyubiquitination, leading to activation of JNK/AP-1 and promotion of cancer cell invasion. Cell Communication and Signaling 15:1.
Crossref
Alessandra Zingoni, Cinzia Fionda, Cristiana Borrelli, Marco Cippitelli, Angela Santoni & Alessandra Soriani. (2017) Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance. Frontiers in Immunology 8.
Crossref
Michael Krainer & Ahmed El-Gazzar. 2017. Cancer Therapeutic Targets. Cancer Therapeutic Targets 871 880 .
Zhiqiang Ma, Chongxi Fan, Yang Yang, Shouyin Di, Wei Hu, Tian Li, Yifang Zhu, Jing Han, Zhenlong Xin, Guiling Wu, Jing Zhao, Xiaofei Li & Xiaolong Yan. (2016) Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation. Scientific Reports 6:1.
Crossref
Cheng-Chang Yeh, Hui-Hsin Ko, Yu-Ping Hsieh, King-Jean Wu, Mark Yen -Ping Kuo & Yi-Ting Deng. (2016) Phenethyl isothiocyanate enhances TRAIL-induced apoptosis in oral cancer cells and xenografts. Clinical Oral Investigations 20:9, pages 2343-2352.
Crossref
Cui-cui Liu, Ding-jun Hao, Qian Zhang, Jing An, Jing-jing Zhao, Bo Chen, Ling-ling Zhang & Hao Yang. (2016) Application of bee venom and its main constituent melittin for cancer treatment. Cancer Chemotherapy and Pharmacology 78:6, pages 1113-1130.
Crossref
Weilong Yao, You-Take Oh, Jiusheng Deng, Ping Yue, Liang Deng, Henry Huang, Wei Zhou & Shi-Yong Sun. (2016) Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition. Journal of Biological Chemistry 291:41, pages 21694-21702.
Crossref
Jing Wu, Ye Ding, Chuan-Huizhi Chen, Zhongmei Zhou, Chunyong Ding, Haiying Chen, Jia Zhou & Ceshi Chen. (2016) A new oridonin analog suppresses triple-negative breast cancer cells and tumor growth via the induction of death receptor 5. Cancer Letters 380:2, pages 393-402.
Crossref
Jie Zheng, Dong Ju Son, Sun Mi Gu, Ju Rang Woo, Young Wan Ham, Hee Pom Lee, Wun Jae Kim, Jae Kyung Jung & Jin Tae Hong. (2016) Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathway. Scientific Reports 6:1.
Crossref
Jie Zheng, Hye Lim Lee, Young Wan Ham, Ho Sueb Song, Min Jong Song & Jin Tae Hong. (2015) Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B. Oncotarget 6:42, pages 44437-44451.
Crossref
Jie Zheng, Mi Hee Park, Dong Ju Son, Min Gi Choi, Jeong Soon Choi, Kyung Tak Nam, Hae Deun Kim, Kevin Rodriguez, Benjamin Gann, Young Wan Ham, Sang Bae Han & Jin Tae Hong. (2015) (E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice. Oncotarget 6:39, pages 41929-41943.
Crossref
Xianfang Liu, Sen Guo, Xiangguo Liu & Ling Su. (2015) Chaetocin induces endoplasmic reticulum stress response and leads to death receptor 5-dependent apoptosis in human non-small cell lung cancer cells. Apoptosis 20:11, pages 1499-1507.
Crossref
Lele Song, Yuemin Li, Baoming He & Yuan Gong. (2015) Development of Small Molecules Targeting the Wnt Signaling Pathway in Cancer Stem Cells for the Treatment of Colorectal Cancer. Clinical Colorectal Cancer 14:3, pages 133-145.
Crossref
M. E. Gasparian, M. L. Bychkov, A. V. Yagolovich, D. A. Dolgikh & M. P. Kirpichnikov. (2015) Mutations enhancing selectivity of antitumor cytokine TRAIL to DR5 receptor increase its cytotoxicity against tumor cells. Biochemistry (Moscow) 80:8, pages 1080-1091.
Crossref
ZHONGYI CUI, CAIHONG LI, XIANGYONG LI, QUNZHOU ZHANG, YUEFEI ZHANG, JINGJING SHAO & KEYUAN ZHOU. (2015) Sodium selenite (Na2SeO3) induces apoptosis through the mitochondrial pathway in CNE-2 nasopharyngeal carcinoma cells. International Journal of Oncology 46:6, pages 2506-2514.
Crossref
Tianliang Li, Ling Su, Yuanjiu Lei, Xianfang Liu, Yajing Zhang & Xiangguo Liu. (2015) DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer Cells. Journal of Biological Chemistry 290:17, pages 11108-11118.
Crossref
Jiao Li, Qiuyuan Wen, Lina Xu, Weiyuan Wang, Jiadi Luo, Shuzhou Chu, Guiyuan Xie, Lei Shi, Donghai Huang, Jinghe Li & Songqing Fan. (2014) Fatty acid synthase–associated protein with death domain: a prognostic factor for survival in patients with nasopharyngeal carcinoma. Human Pathology 45:12, pages 2447-2452.
Crossref
Maxim L. Bychkov, Marine E. Gasparian, Dmitry A. Dolgikh & Mikhail P. Kirpichnikov. (2014) Combination of TRAIL with Bortezomib Shifted Apoptotic Signaling from DR4 to DR5 Death Receptor by Selective Internalization and Degradation of DR4. PLoS ONE 9:10, pages e109756.
Crossref
Saet-Byul Oh, Chul Ju Hwang, Suk-Young Song, Yu Yeon Jung, Hyung-Mun Yun, Chang Hyun Sok, Ha Chang Sung, Jin-Mu Yi, Dong Hyun Park, Young Wan Ham, Sang Bae Han, Bang Yeon Hwang & Jin Tae Hong. (2014) Anti-cancer effect of tectochrysin in NSCLC cells through overexpression of death receptor and inactivation of STAT3. Cancer Letters 353:1, pages 95-103.
Crossref
Chieh-Lin Jerry Teng, Shao-Min Han, Wei-Cheng Wu, Chi-Mei Hsueh, Jia-Rong Tsai, Wen-Li Hwang & Shih-Lan Hsu. (2014) Mechanistic aspects of lauryl gallate-induced differentiation and apoptosis in human acute myeloid leukemia cells. Food and Chemical Toxicology 71, pages 197-206.
Crossref
Arumugam Nagalingam, Panjamurthy Kuppusamy, Shivendra V. Singh, Dipali Sharma & Neeraj K. Saxena. (2014) Mechanistic Elucidation of the Antitumor Properties of Withaferin A in Breast Cancer. Cancer Research 74:9, pages 2617-2629.
Crossref
Kyung Eun Choi, Young Suk Jung, Dea Hwan Kim, Ju Kyung Song, Ji Young Kim, Yu Yeon Jung, So Young Eum, Joo Hwan Kim, Na Young Yoon, Hwan Soo Yoo, Sang-Bae Han & Jin Tae Hong. (2014) Myriocin induces apoptotic lung cancer cell death via activation of DR4 pathway. Archives of Pharmacal Research 37:4, pages 501-511.
Crossref
Pushpa Saranya Kollipara, Do Hee Won, Chul Ju Hwang, Yu Yeon Jung, Heui Seoung Yoon, Mi Hee Park, Min Jong Song, Ho Sueb Song & Jin Tae Hong. (2014) Enhanced Anti-Cancer Effect of Snake Venom Activated NK Cells on Lung Cancer Cells by Inactivation of NF-κB. Biomolecules & Therapeutics 22:2, pages 106-113.
Crossref
Pushpa Saranya Kollipara, Jung Hyun Kim, Dohee Won, Sang Min Lee, Ha Chang Sung, Hyun Sok Chang, Kang Tae Lee, Kang Sik Lee, Mi Hee Park, Min Jong Song, Ho Sueb Song & Jin Tae Hong. (2014) Co-culture with NK-92MI cells enhanced the anti-cancer effect of bee venom on NSCLC cells by inactivation of NF-κB. Archives of Pharmacal Research 37:3, pages 379-389.
Crossref
Kentaro Kai, Kaei Nasu, Yukie Kawano, Yoko Aoyagi, Yoshiyuki Tsukamoto, Naoki Hijiya, Wakana Abe, Mamiko Okamoto, Masatsugu Moriyama & Hisashi Narahara. (2013) Death Receptor 6 is Epigenetically Silenced by Histone Deacetylation in Endometriosis and Promotes the Pathogenesis of Endometriosis. American Journal of Reproductive Immunology 70:6, pages 485-496.
Crossref
Hui Ren, Liqun Zhao, Yikun Li, Ping Yue, Xingming Deng, Taofeek K. Owonikoko, Mingwei Chen, Fadlo R. Khuri & Shi-Yong Sun. (2013) The PI3 kinase inhibitor NVP-BKM120 induces GSK3/FBXW7-dependent Mcl-1 degradation, contributing to induction of apoptosis and enhancement of TRAIL-induced apoptosis. Cancer Letters 338:2, pages 229-238.
Crossref
Hiroo Hasegawa & Shimeru Kamihira. (2013) Use of diagnostic and therapeutic biomarkers in personalized oncology based on adult T-cell leukemia/lymphoma research. Personalized Medicine Universe 2, pages 7-11.
Crossref
Qingyong Li, Li Zhang, Yuangang Zu, Tianyu Liu, Baoyou Zhang & Wuna He. (2013) Generation of reactive oxygen species by a novel berberine–bile acid analog mediates apoptosis in hepatocarcinoma SMMC-7721 cells. Biochemical and Biophysical Research Communications 433:4, pages 432-437.
Crossref
Liqun Zhao, Ping Yue, Fadlo R. Khuri & Shi-Yong Sun. (2013) mTOR Complex 2 Is Involved in Regulation of Cbl-Dependent c-FLIP Degradation and Sensitivity of TRAIL-Induced Apoptosis. Cancer Research 73:6, pages 1946-1957.
Crossref
Pushpa Saranya Kollipara, Heon Sang Jeong, Sang Bae Han & Jin Tae Hong. (2013) ( E )-2,4-bis( p -hydroxyphenyl)-2-butenal has an antiproliferative effect on NSCLC cells induced by p38 MAPK-mediated suppression of NF-κB and up-regulation of TNFRSF10B (DR5) . British Journal of Pharmacology 168:6, pages 1471-1484.
Crossref
Michael Krainer & Ahmed El-Gazzar. 2016. Cancer Therapeutic Targets. Cancer Therapeutic Targets 1 10 .
Ung-Soo Lee, Jung Ok Ban, Eung Tae Yeon, Hee Pom Lee, Venkatareddy Udumula, Young Wan Ham & Jin Tae Hong. (2012) Growth Inhibitory Effect of (E)-2,4-bis(p-hydroxyphenyl)-2-Butenal Diacetate through Induction of Apoptotic Cell Death by Increasing DR3 Expression in Human Lung Cancer Cells. Biomolecules and Therapeutics 20:6, pages 538-543.
Crossref
Linyan Xu, Ling Su & Xiangguo Liu. (2012) PKCδ Regulates Death Receptor 5 Expression Induced by PS-341 through ATF4–ATF3/CHOP Axis in Human Lung Cancer Cells. Molecular Cancer Therapeutics 11:10, pages 2174-2182.
Crossref
Chung-hsin Yeh, Yu-yen Yang, Ya-fang Huang, Kuan-chih Chow & Ming-feng Chen. (2012) Induction of apoptosis in human Hep3B hepatoma cells by norcantharidin through a p53 independent pathway via TRAIL/DR5 signal transduction. Chinese Journal of Integrative Medicine 18:9, pages 676-682.
Crossref
Shin-Hyung Park, Jeong-Hwan Kim, Gyoo Yong Chi, Gi-Young Kim, Young-Chae Chang, Sung-Kwon Moon, Soo-Wan Nam, Wun-Jae Kim, Young Hyun Yoo & Yung Hyun Choi. (2012) Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species. Toxicology Letters 212:3, pages 252-261.
Crossref
Guangbo Liu, Ling Su, Xuexi Hao, Ning Zhong, Diansheng Zhong, Sunil Singhal & Xiangguo Liu. (2012) Salermide up‐regulates death receptor 5 expression through the ATF4‐ATF3‐CHOP axis and leads to apoptosis in human cancer cells. Journal of Cellular and Molecular Medicine 16:7, pages 1618-1628.
Crossref
Carmine Stolfi, Francesco Pallone & Giovanni Monteleone. (2012) Molecular Targets of TRAIL-Sensitizing Agents in Colorectal Cancer. International Journal of Molecular Sciences 13:7, pages 7886-7901.
Crossref
Bo Li, Hui Ren, Ping Yue, Mingwei Chen, Fadlo R. Khuri & Shi-Yong Sun. (2012) The Novel Akt Inhibitor API-1 Induces c-FLIP Degradation and Synergizes with TRAIL to Augment Apoptosis Independent of Akt Inhibition. Cancer Prevention Research 5:4, pages 612-620.
Crossref
You-Take Oh, Ping Yue, Wei Zhou, Justin M. Balko, Esther P. Black, Taofeek K. Owonikoko, Fadlo R. Khuri & Shi-Yong Sun. (2012) Oncogenic Ras and B-Raf Proteins Positively Regulate Death Receptor 5 Expression through Co-activation of ERK and JNK Signaling. Journal of Biological Chemistry 287:1, pages 257-267.
Crossref
Miran Jo, Mi Hee Park, Pushpa Saranya Kollipara, Byeong Jun An, Ho Sueb Song, Sang Bae Han, Jang Heub Kim, Min Jong Song & Jin Tae Hong. (2012) Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway. Toxicology and Applied Pharmacology 258:1, pages 72-81.
Crossref
Chieko Kudo, Hiroyuki Yamakoshi, Atsuko Sato, Hiroshi Nanjo, Hisatsugu Ohori, Chikashi Ishioka, Yoshiharu Iwabuchi & Hiroyuki Shibata. (2011) Synthesis of 86 species of 1,5-diaryl-3-oxo-1,4-pentadienes analogs of curcumin can yield a good lead in vivo. BMC Pharmacology 11:1.
Crossref
Liqun Zhao, Ping Yue, Sagar Lonial, Fadlo R. Khuri & Shi-Yong Sun. (2011) The NEDD8-Activating Enzyme Inhibitor, MLN4924, Cooperates with TRAIL to Augment Apoptosis through Facilitating c-FLIP Degradation in Head and Neck Cancer Cells. Molecular Cancer Therapeutics 10:12, pages 2415-2425.
Crossref
Yuko Kojima, Masafumi Nakayama, Takashi Nishina, Hiroyasu Nakano, Makoto Koyanagi, Kazuyoshi Takeda, Ko Okumura & Hideo Yagita. (2011) Importin β1 Protein-mediated Nuclear Localization of Death Receptor 5 (DR5) Limits DR5/Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Cell Death of Human Tumor Cells. Journal of Biological Chemistry 286:50, pages 43383-43393.
Crossref
Ling Su, Guangbo Liu, Xuexi Hao, Ning Zhong, Diansheng Zhong, Xiangguo Liu & Sunil Singhal. (2011) Death Receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells. European Journal of Cancer 47:16, pages 2471-2478.
Crossref
Katrina A. Schinske, Shyam Nyati, Amjad P. Khan, Terence M. Williams, Timothy D. Johnson, Brian D. Ross, Ricardo Pérez Tomás & Alnawaz Rehemtulla. (2011) A Novel Kinase Inhibitor of FADD Phosphorylation Chemosensitizes through the Inhibition of NF-κB. Molecular Cancer Therapeutics 10:10, pages 1807-1817.
Crossref
Carmine Stolfi, Roberta Caruso, Eleonora Franzè, Angelamaria Rizzo, Angela Rotondi, Ivan Monteleone, Massimo Claudio Fantini, Francesco Pallone & Giovanni Monteleone. (2011) 2-Methoxy-5-Amino- N -Hydroxybenzamide Sensitizes Colon Cancer Cells to TRAIL-Induced Apoptosis by Regulating Death Receptor 5 and Survivin Expression . Molecular Cancer Therapeutics 10:10, pages 1969-1981.
Crossref
Burcak Yoldas, Cem Ozer, Ozlem Ozen, Tuba Canpolat, Isilay Dogan, Thomas S. Griffith, Salih Sanlioglu & Levent N. Ozluoglu. (2011) Clinical significance of TRAIL and TRAIL receptors in patients with head and neck cancer. Head & Neck 33:9, pages 1278-1284.
Crossref
Latha Dhandapani, Ping Yue, Suresh S. Ramalingam, Fadlo R. Khuri & Shi-Yong Sun. (2011) Retinoic Acid Enhances TRAIL-Induced Apoptosis in Cancer Cells by Upregulating TRAIL Receptor 1 Expression. Cancer Research 71:15, pages 5245-5254.
Crossref
Xiaobing Tian, Jiangbin Ye, Michelle Alonso-Basanta, Stephen M. Hahn, Constantinos Koumenis & Jay F. Dorsey. (2011) Modulation of CCAAT/Enhancer Binding Protein Homologous Protein (CHOP)-dependent DR5 Expression by Nelfinavir Sensitizes Glioblastoma Multiforme Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL). Journal of Biological Chemistry 286:33, pages 29408-29416.
Crossref
S. Yin, R. Wang, F. Zhou, H. Zhang & Y. Jing. (2011) Bcl-xL Is a Dominant Antiapoptotic Protein that Inhibits Homoharringtonine-Induced Apoptosis in Leukemia Cells. Molecular Pharmacology 79:6, pages 1072-1083.
Crossref
Lionel Flamant, Annick Notte, Noelle Ninane, Martine Raes & Carine Michiels. (2010) Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia. Molecular Cancer 9:1.
Crossref
You-Take Oh, Xiangguo Liu, Ping Yue, Sumin Kang, Jing Chen, Jack Taunton, Fadlo R. Khuri & Shi-Yong Sun. (2010) ERK/Ribosomal S6 Kinase (RSK) Signaling Positively Regulates Death Receptor 5 Expression through Co-activation of CHOP and Elk1. Journal of Biological Chemistry 285:53, pages 41310-41319.
Crossref
Satindra Gahlot, Mohammad Aslam Khan, Loveena Rishi & Sekhar Majumdar. (2010) Pentoxifylline augments TRAIL/Apo2L mediated apoptosis in cutaneous T cell lymphoma (HuT-78 and MyLa) by modulating the expression of antiapoptotic proteins and death receptors. Biochemical Pharmacology 80:11, pages 1650-1661.
Crossref
Sangnam Oh, Daeho Kwon, Hyun Jeong Lee, Joonhee Kim & Eunil Lee. (2010) Role of elevated pressure in TRAIL-induced apoptosis in human lung carcinoma cells. Apoptosis 15:12, pages 1517-1528.
Crossref
Hong Zhu, Xiao-Wen Liu, Wan-Jing Ding, Dan-Qing Xu, Yu-Chen Zhao, Wei Lu, Qiao-Jun He & Bo Yang. (2010) Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L. Cancer Letters 297:2, pages 155-164.
Crossref
Mi Ra Seon, Soon Sung Lim, Hyun Ju Choi, So Young Park, Han Jin Cho, Jin-Kyu Kim, Jongdai Kim, Dae Young Kwon & Jung Han Yoon Park. (2010) Isoangustone A present in hexane/ethanol extract of Glycyrrhiza uralensis induces apoptosis in DU145 human prostate cancer cells via the activation of DR4 and intrinsic apoptosis pathway . Molecular Nutrition & Food Research 54:9, pages 1329-1339.
Crossref
Martin Grimm, Mia Kim, Andreas Rosenwald, Burkhard von Rahden, Igor Tsaur, Eva Meier, Uwe Heemann, Christoph-Thomas Germer, Martin Gasser & Ana Maria Waaga-Gasser. (2010) Tumour-mediated TRAIL-Receptor expression indicates effective apoptotic depletion of infiltrating CD8+ immune cells in clinical colorectal cancer. European Journal of Cancer 46:12, pages 2314-2323.
Crossref
Richa Tiwary, Weiping Yu, Jing Li, Sook-Kyung Park, Bob G. Sanders & Kimberly Kline. (2010) Role of Endoplasmic Reticulum Stress in α-TEA Mediated TRAIL/DR5 Death Receptor Dependent Apoptosis. PLoS ONE 5:7, pages e11865.
Crossref
Ingrid J. de Vries-van Leeuwen, Chantal Kortekaas-Thijssen, Jean A. Nzigou Mandouckou, Sjors Kas, Antonio Evidente & Albertus H. de Boer. (2010) Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-α priming. Cancer Letters 293:2, pages 198-206.
Crossref
O. Pellerito, G. Calvaruso, P. Portanova, A. De Blasio, A. Santulli, R. Vento, G. Tesoriere & M. Giuliano. (2010) The Synthetic Cannabinoid WIN 55,212-2 Sensitizes Hepatocellular Carcinoma Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis by Activating p8/CCAAT/Enhancer Binding Protein Homologous Protein (CHOP)/Death Receptor 5 (DR5) Axis. Molecular Pharmacology 77:5, pages 854-863.
Crossref
Songqing Fan, Yikun Li, Ping Yue, Fadlo R. Khuri & Shi-Yong Sun. (2010) The eIF4E/eIF4G Interaction Inhibitor 4EGI-1 Augments TRAIL-Mediated Apoptosis through c-FLIP Down-regulation and DR5 Induction Independent of Inhibition of Cap-Dependent Protein Translation. Neoplasia 12:4, pages 346-IN7.
Crossref
T Trarbach, M Moehler, V Heinemann, C-H Köhne, M Przyborek, C Schulz, V Sneller, G Gallant & S Kanzler. (2010) Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer. British Journal of Cancer 102:3, pages 506-512.
Crossref
Gregory Mellier, Sinong Huang, Kirthan Shenoy & Shazib Pervaiz. (2010) TRAILing death in cancer. Molecular Aspects of Medicine 31:1, pages 93-112.
Crossref
Anna M. Giammarioli, Rosa Vona, Lucrezia Gambardella, Barbara Ascione, Angela Maselli, Cristiana Barbati, Antonella Tinari & Walter Malorni. (2009) Interferon‐γ bolsters CD95/Fas‐mediated apoptosis of astroglioma cells. The FEBS Journal 276:20, pages 5920-5935.
Crossref
David S. Schrump. (2009) Cytotoxicity Mediated by Histone Deacetylase Inhibitors in Cancer Cells: Mechanisms and Potential Clinical Implications. Clinical Cancer Research 15:12, pages 3947-3957.
Crossref
Claudia Jursik, Michaela Prchal, Regina Grillari-Voglauer, Karel Drbal, Elke Fuertbauer, Herbert Jungfer, Winfried H. Albert, Eva Steinhuber, Thomas Hemetsberger, Johannes Grillari, Hannes Stockinger & Hermann Katinger. (2009) Large-Scale Production and Characterization of Novel CD4+ Cytotoxic T Cells with Broad Tumor Specificity for Immunotherapy. Molecular Cancer Research 7:3, pages 339-353.
Crossref
Yuanming Lu, Sabah Ansar, Mary L. Michaelis & Brian S.J. Blagg. (2009) Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line. Bioorganic & Medicinal Chemistry 17:4, pages 1709-1715.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.