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Research Paper

PBEF1/NAmPRTase/Visfatin: A potential malignant astrocytoma/glioblastoma serum marker with prognostic value

Pages 663-668 | Published online: 01 Jun 2008

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Eman A. Al Abdulsalam & Rowyda N. Al Harithy. (2021) Visfatin and global histone H3K9me levels in colon cancer. Annals of Medicine 53:1, pages 647-652.
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Keivan Sadrerafi, Emilia O Mason & Mark W Lee$suffix/text()$suffix/text(). (2018) Clickable prodrugs bearing potent and hydrolytically cleavable nicotinamide phosphoribosyltransferase inhibitors. Drug Design, Development and Therapy 12, pages 987-995.
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Anne Roulston & Gordon C. Shore. (2016) New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncology. Molecular & Cellular Oncology 3:1.
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Savita Jayaram, Manoj Kumar Gupta, Ravindra Varma Polisetty, William CS Cho & Ravi Sirdeshmukh. (2014) Towards developing biomarkers for glioblastoma multiforme: a proteomics view. Expert Review of Proteomics 11:5, pages 621-639.
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Mark Watson, Anne Roulston, Laurent Bélec, Xavier Billot, Richard Marcellus, Dominique Bédard, Cynthia Bernier, Stéphane Branchaud, Helen Chan, Kenza Dairi, Karine Gilbert, Daniel Goulet, Michel-Olivier Gratton, Henady Isakau, Anne Jang, Abdelkrim Khadir, Elizabeth Koch, Manon Lavoie, Michael Lawless, Mai Nguyen, Denis Paquette, Émilie Turcotte, Alvin Berger, Matthew Mitchell, Gordon C. Shore & Pierre Beauparlant. (2009) The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors. Molecular and Cellular Biology 29:21, pages 5872-5888.
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Kumaravel Somasundaram, Mamatha B Nijaguna & Durairaj Mohan Kumar. (2009) Serum proteomics of glioma: methods and applications. Expert Review of Molecular Diagnostics 9:7, pages 695-707.
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Xiaotong Zhu, Haixia Liu, Li Chen, Chenxu Wu, Xuesong Liu, Yong Cang, Biao Jiang, Xiaobao Yang & Gaofeng Fan. (2022) Addressing the Enzyme-independent tumor-promoting function of NAMPT via PROTAC-mediated degradation. Cell Chemical Biology 29:11, pages 1616-1629.e12.
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Yichen Wei, Haotian Xiang & Wenqiu Zhang. (2022) Review of various NAMPT inhibitors for the treatment of cancer. Frontiers in Pharmacology 13.
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Maximilian Clausing, Doreen William, Matthias Preussler, Julia Biedermann, Konrad Grützmann, Susan Richter, Frank Buchholz, Achim Temme, Evelin Schröck & Barbara Klink. (2022) Different Effects of RNAi-Mediated Downregulation or Chemical Inhibition of NAMPT in an Isogenic IDH Mutant and Wild-Type Glioma Cell Model. International Journal of Molecular Sciences 23:10, pages 5787.
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Alyson Curry, Dawanna White & Yana Cen. (2022) Small Molecule Regulators Targeting NAD+ Biosynthetic Enzymes. Current Medicinal Chemistry 29:10, pages 1718-1738.
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Jiaqi Liu, Xianzun Tao, Yi Zhu, Chong Li, Kai Ruan, Zoraida Diaz-Perez, Priyamvada Rai, Hongbo Wang & R Grace Zhai. (2021) NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis. eLife 10.
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Bin Xiang, Xin Yue Wang & Ke Jian Liu. (2021) Dual Roles of Nicotinamide Phosphoribosyltransferase as a Promising Target for Cancer Radiotherapy. Radiation Research 196:4.
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Lola E. Navas & Amancio Carnero. (2021) NAD+ metabolism, stemness, the immune response, and cancer. Signal Transduction and Targeted Therapy 6:1.
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Meenakshi Vachher, Kriti Arora, Archana Burman & Bhupender Kumar. (2019) NAMPT, GRN, and SERPINE1 signature as predictor of disease progression and survival in gliomas. Journal of Cellular Biochemistry 121:4, pages 3010-3023.
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Masoumeh Mohammadi, Ali Moradi, Javad Farhadi, Abolfazl Akbari, Shokoufeh Pourmandi & Hassan Mehrad-Majd. (2020) Prognostic value of visfatin in various human malignancies: A systematic review and meta-analysis. Cytokine 127, pages 154964.
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Antonio Lucena-Cacace, Masayuki Umeda, Lola E. Navas & Amancio Carnero. (2019) NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance. Frontiers in Oncology 9.
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Petr Svoboda, Edita Krizova, Sarka Sestakova, Kamila Vapenkova, Zdenek Knejzlik, Silvie Rimpelova, Diana Rayova, Nikol Volfova, Ivana Krizova, Michaela Rumlova, David Sykora, Rene Kizek, Martin Haluzik, Vaclav Zidek, Jarmila Zidkova & Vojtech Skop. (2019) Nuclear transport of nicotinamide phosphoribosyltransferase is cell cycle–dependent in mammalian cells, and its inhibition slows cell growth. Journal of Biological Chemistry 294:22, pages 8676-8689.
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Li-Juan ZhangXue-Qin LiCun-De WangLi ZhuangQuan GongShi-Juan LiXin LiuHui DongXi-Cai Wang. (2018) The Correlation of Visfatin and Its Gene Polymorphism with Non-Small Cell Lung Cancer. Cancer Biotherapy and Radiopharmaceuticals 33:10, pages 460-465.
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Nikolaos Spyrou, Konstantinos I. Avgerinos, Christos S. Mantzoros & Maria Dalamaga. (2018) Classic and Novel Adipocytokines at the Intersection of Obesity and Cancer: Diagnostic and Therapeutic Strategies. Current Obesity Reports 7:4, pages 260-275.
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Byung-Cheol Lee, Jisun Song, Arim Lee, Daeho Cho & Tae Kim. (2018) Visfatin Promotes Wound Healing through the Activation of ERK1/2 and JNK1/2 Pathway. International Journal of Molecular Sciences 19:11, pages 3642.
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Piotr Celichowski, Karol Jopek, Marta Szyszka, Paulina Milecka, Ludwik K. Malendowicz, Marianna Tyczewska & Marcin Ruciński. (2018) Nampt (Visfatin) Influence on Proliferative Activity of Normal Rat Adrenocortical Cells and Human Adrenal Corticocarcinoma Nci-H295r Cells. Medical Journal of Cell Biology 6:2, pages 33-38.
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Maria Dalamaga, Gerasimos Socrates Christodoulatos & Christos S. Mantzoros. (2018) The role of extracellular and intracellular Nicotinamide phosphoribosyl-transferase in cancer: Diagnostic and therapeutic perspectives and challenges. Metabolism 82, pages 72-87.
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Antonio Sica, Laura Strauss, Francesca Maria Consonni, Cristina Travelli, Armando Genazzani & Chiara Porta. (2017) Metabolic regulation of suppressive myeloid cells in cancer. Cytokine & Growth Factor Reviews 35, pages 27-35.
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Grzegorz Słomian, Elżbieta Świętochowska, Grzegorz Nowak, Krystyna Pawlas, Aleksandra Żelazko & Przemysław Nowak. (2017) Chemotherapy and plasma adipokines level in patients with colorectal cancer. Postępy Higieny i Medycyny Doświadczalnej 71:1, pages 0-0.
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Federico Carbone, Luca Liberale, Aldo Bonaventura, Alessandra Vecchiè, Matteo Casula, Michele Cea, Fiammetta Monacelli, Irene Caffa, Santina Bruzzone, Fabrizio Montecucco & Alessio Nencioni. 2011. Comprehensive Physiology. Comprehensive Physiology 603 621 .
Haijun Li, E. Bai, Yong Zhang, Zhuoqi Jia, Shicai He & Junke Fu. (2017) Role of Nampt and Visceral Adiposity in Esophagogastric Junction Adenocarcinoma. Journal of Immunology Research 2017, pages 1-7.
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Maria Dalamaga & Gerasimos Socrates Christodoulatos. 2017. Adipocytokines, Energy Balance, and Cancer. Adipocytokines, Energy Balance, and Cancer 109 136 .
Barry E. Kennedy, Tanveer Sharif, Emma Martell, Cathleen Dai, Youra Kim, Patrick W.K. Lee & Shashi A. Gujar. (2016) NAD+ salvage pathway in cancer metabolism and therapy. Pharmacological Research 114, pages 274-283.
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Marine Barraud, Jonathan Garnier, Celine Loncle, Odile Gayet, Charlotte Lequeue, Sophie Vasseur, Benjamin Bian, Pauline Duconseil, Marine Gilabert, Martin Bigonnet, Aurélie Maignan, Vincent Moutardier, Stephane Garcia, Olivier Turrini, Jean-Robert Delpero, Marc Giovannini, Philippe Grandval, Mohamed Gasmi, Mehdi Ouaissi, Veronique Secq, Flora Poizat, Nicolas Guibert, Juan Iovanna & Nelson Dusetti. (2016) A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT. Oncotarget 7:33, pages 53783-53796.
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Ambra A Grolla, Cristina Travelli, Armando A Genazzani & Jaswinder K Sethi. (2016) Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine . British Journal of Pharmacology 173:14, pages 2182-2194.
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Jyothi Padiadpu, Madhulika Mishra, Eshita Sharma, Uchurappa Mala, Kumar Somasundaram & Nagasuma Chandra. (2016) Probing the Druggability Limits for Enzymes of the NAD Biosynthetic Network in Glioma. Journal of Chemical Information and Modeling 56:5, pages 843-853.
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Sara Duarte-Pereira, Isabel Pereira-Castro, Sarah S. Silva, Mariana Gonçalves Correia, Célia Neto, Luís Teixeira da Costa, António Amorim & Raquel M. Silva. (2015) Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors. Oncotarget 7:2, pages 1973-1983.
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YANYAN ZHU, MEIYAN GUO, LINGYUN ZHANG, TAO XU, LI WANG & GUOXIONG XU. (2016) Biomarker triplet NAMPT/VEGF/HER2 as a de novo detection panel for the diagnosis and prognosis of human breast cancer. Oncology Reports 35:1, pages 454-462.
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Jun Feng, Peng-Fei Yan, Hong-yang Zhao, Fang-Cheng Zhang, Wo-Hua Zhao & Min Feng. (2016) Inhibitor of Nicotinamide Phosphoribosyltransferase Sensitizes Glioblastoma Cells to Temozolomide via Activating ROS/JNK Signaling Pathway. BioMed Research International 2016, pages 1-11.
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Keivan Sadrerafi, Emilia O. Zargham & Mark W. LeeJr.Jr.. (2016) Improved synthesis of MC4-PPEA and the biological evaluation of its hydroxymethyl derivative. Bioorganic & Medicinal Chemistry Letters 26:2, pages 618-621.
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Antje Garten, Susanne Schuster, Melanie Penke, Theresa Gorski, Tommaso de Giorgis & Wieland Kiess. (2015) Physiological and pathophysiological roles of NAMPT and NAD metabolism. Nature Reviews Endocrinology 11:9, pages 535-546.
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GONG CHENG, CHANGYING LIU, XIUJIANG SUN, LEI ZHANG, LIFANG LIU, JUN OUYANG & BO LI. (2015) Visfatin promotes osteosarcoma cell migration and invasion via induction of epithelial-mesenchymal transition. Oncology Reports 34:2, pages 987-994.
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Deepak Sampath, Tanja S. Zabka, Dinah L. Misner, Thomas O’Brien & Peter S. Dragovich. (2015) Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer. Pharmacology & Therapeutics 151, pages 16-31.
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Matthew N.T. Thuy, Jeremy K.T. Kam, Geoffrey C.Y. Lee, Peter L. Tao, Dorothy Q. Ling, Melissa Cheng, Su Kah Goh, Alexander J. Papachristos, Lipi Shukla, Krystal-Leigh Wall, Nicolas R. Smoll, Jordan J. Jones, Njeri Gikenye, Bob Soh, Brad Moffat, Nick Johnson & Katharine J. Drummond. (2015) A novel literature-based approach to identify genetic and molecular predictors of survival in glioblastoma multiforme: Analysis of 14,678 patients using systematic review and meta-analytical tools. Journal of Clinical Neuroscience 22:5, pages 785-799.
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Debora Soncini, Irene Caffa, Gabriele Zoppoli, Michele Cea, Antonia Cagnetta, Mario Passalacqua, Luca Mastracci, Silvia Boero, Fabrizio Montecucco, Giovanna Sociali, Denise Lasigliè, Patrizia Damonte, Alessia Grozio, Elena Mannino, Alessandro Poggi, Vito G. D'Agostino, Fiammetta Monacelli, Alessandro Provenzani, Patrizio Odetti, Alberto Ballestrero, Santina Bruzzone & Alessio Nencioni. (2014) Nicotinamide Phosphoribosyltransferase Promotes Epithelial-to-Mesenchymal Transition as a Soluble Factor Independent of Its Enzymatic Activity. Journal of Biological Chemistry 289:49, pages 34189-34204.
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Li-Wen Lin, Yung-Chuan Lu, Chao-Ping Wang, Chia-Chang Hsu, Li-Fen Lu, Ming-Che Hsin, I.- Ting Tsai, Fu-Mei Chung, Jer-Yiing Houng, Lee Yau-Jiunn & Chih-Yu Chen. (2014) Visfatin/pre-B cell colony-enhancing factor immunohistochemical overexpression in oral cancers. Journal of Applied Biomedicine 12:4, pages 255-262.
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Grzegorz Słomian, Elżbieta Świętochowska, Jolanta Malinowska-Borowska, Sławomir Kasperczyk, Anna Rogalska & Przemysław Nowak. (2014) Association between chemotherapy and plasma adipokines in patients with colorectal cancer. Pharmacological Reports 66:5, pages 902-907.
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J. M. Kros, D. M. Mustafa, L. J. M. Dekker, P. A. E. Sillevis Smitt, T. M. Luider & P.-P. Zheng. (2014) Circulating glioma biomarkers. Neuro-Oncology.
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Sara Duarte-Pereira, Sarah S. Silva, Luísa Azevedo, Luísa Castro, António Amorim & Raquel M. Silva. (2014) NAMPT and NAPRT1: novel polymorphisms and distribution of variants between normal tissues and tumor samples. Scientific Reports 4:1.
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Guo-Wen Lu, Qi-Jun Wang, Min-Ming Xia & Jiao Qian. (2014) Elevated plasma visfatin levels correlate with poor prognosis of gastric cancer patients. Peptides 58, pages 60-64.
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Szymon Skoczen, Przemyslaw J. Tomasik, Jolanta Gozdzik, Kamil Fijorek, Aleksandra Krasowska-Kwiecien, Oktawiusz Wiecha, Wojciech Czogala, Agnieszka Dluzniewska, Krystyna Sztefko, Jerzy Starzyk & Maciej Siedlar. (2014) Visfatin concentrations in children with leukemia before and after stem cell transplantation. Experimental Hematology 42:4, pages 252-260.
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Kelly J. Gauger, Lotfi M. Bassa, Elizabeth M. Henchey, Josephine Wyman, Brooke Bentley, Melissa Brown, Akihiko Shimono & Sallie S. Schneider. (2013) Mice Deficient in Sfrp1 Exhibit Increased Adiposity, Dysregulated Glucose Metabolism, and Enhanced Macrophage Infiltration. PLoS ONE 8:12, pages e78320.
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Zong-Liang Jia. (2013) Diet-induced obesity promotes murine gastric cancer growth through a nampt/sirt1/c-myc positive feedback loop. Oncology Reports.
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RAFAŁ JAKUB BUŁDAK, ŁUKASZ BUŁDAK, RENATA POLANIAK, MICHAŁ KUKLA, EWA BIRKNER, ROBERT KUBINA, AGATA KABAŁA-DZIK, ANNA DUŁAWA-BUŁDAK & KRYSTYNA ŻWIRSKA-KORCZALA. (2013) Visfatin affects redox adaptative responses and proliferation in Me45 human malignant melanoma cells: An in vitro study. Oncology Reports 29:2, pages 771-778.
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Elena Maldi, Cristina Travelli, Antonio Caldarelli, Nicolò Agazzone, Sara Cintura, Ubaldina Galli, Maria Scatolini, Paola Ostano, Benedetta Miglino, Giovanna Chiorino, Renzo Boldorini & Armando A. Genazzani. (2013) Nicotinamide phosphoribosyltransferase (NAMPT) is over-expressed in melanoma lesions. Pigment Cell & Melanoma Research 26:1, pages 144-146.
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HAI-JUN LI, XIANG-MING CHE, WEI ZHAO, SHI-CAI HE, ZHENG-LIANG ZHANG & RUI CHEN. (2012) Diet-induced obesity potentiates the growth of gastric cancer in mice. Experimental and Therapeutic Medicine 4:4, pages 615-620.
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Sarah C. Bowlby, Michael J. Thomas, Ralph B. D’Agostino & Steven J. Kridel. (2012) Nicotinamide Phosphoribosyl Transferase (Nampt) Is Required for De Novo Lipogenesis in Tumor Cells. PLoS ONE 7:6, pages e40195.
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Shunsuke Okumura, Takaaki Sasaki, Yoshinori Minami & Yoshinobu Ohsaki. (2012) Nicotinamide Phosphoribosyltransferase: A Potent Therapeutic Target in Non-small Cell Lung Cancer with Epidermal Growth Factor Receptor-Gene Mutation. Journal of Thoracic Oncology 7:1, pages 49-56.
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Pei Wang, Paul M. Vanhoutte & Chao-Yu Miao. (2012) Visfatin and Cardio–Cerebro–Vascular Disease. Journal of Cardiovascular Pharmacology 59:1, pages 1-9.
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Li-Yuan Zhang, Li-Ying Liu, Ling-Ling Qie, Ka-Na Ling, Li-Hua Xu, Feng Wang, San-Hua Fang, Yun-Bi Lu, Hua Hu, Er-Qing Wei & Wei-Ping Zhang. (2012) Anti-proliferation effect of APO866 on C6 glioblastoma cells by inhibiting nicotinamide phosphoribosyltransferase. European Journal of Pharmacology 674:2-3, pages 163-170.
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Ruo-Yu Zhang, Ye Qin, Xiao-Qun Lv, Pei Wang, Tian-Ying Xu, Lei Zhang & Chao-Yu Miao. (2011) A fluorometric assay for high-throughput screening targeting nicotinamide phosphoribosyltransferase. Analytical Biochemistry 412:1, pages 18-25.
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ZHENG-HAO Deng, Hui-Qiu Cao, Yong-Bin Hu, Ji-Fang Wen & Jian-Hua Zhou. (2011) TRX is up-regulated by fibroblast growth factor-2 in lung carcinoma. APMIS 119:1, pages 57-65.
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Weiping Zhang, Yicheng Xie, Tiannan Wang, Jing Bi, Hailong Li, Li Qin Zhang, Shui Qing Ye & Shinghua Ding. (2010) Neuronal Protective Role of PBEF in a Mouse Model of Cerebral Ischemia. Journal of Cerebral Blood Flow & Metabolism 30:12, pages 1962-1971.
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Jee-Young Kim, Yun-Hee Bae, Moon-Kyoung Bae, Su-Ryun Kim, Hyun-Joo Park, Hee-Jun Wee & Soo-Kyung Bae. (2009) Visfatin through STAT3 activation enhances IL-6 expression that promotes endothelial angiogenesis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1793:11, pages 1759-1767.
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