Citations (70)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Mengyuan Li & Donghua Zhang. (2022) DNA methyltransferase-1 in acute myeloid leukaemia: beyond the maintenance of DNA methylation. Annals of Medicine 54:1, pages 2011-2023.
Read now
Read now
Govind Babu, Padmaparna Chaudhuri, Manoj Rajappa, Manjusha Biswas, Bipinesh Sansar, Chethan Rajegowda, Aneesha Radhakrishnan, Jayshree Advani, Biplab Tewary, Padhma Radhakrishnan, Saravanan Thiyagarajan, Aditi Chatterjee, Ram Shankar Upadhayaya & Pradip K Majumder. (2021) JAK-STAT inhibitor as a potential therapeutic opportunity in AML patients resistant to cytarabine and epigenetic therapy. Cancer Biology & Therapy 22:1, pages 66-78.
Read now
Read now
Judit Symmank, Cathrin Bayer, Christiane Schmidt, Anne Hahn, Daniel Pensold & Geraldine Zimmer-Bensch. (2018) DNMT1 modulates interneuron morphology by regulating Pak6 expression through crosstalk with histone modifications. Epigenetics 13:5, pages 536-556.
Read now
Read now
Jonathan How, Mark D. Minden, Leber Brian, Eric X. Chen, Joseph Brandwein, Andre C. Schuh, Aaron D. Schimmer, Vikas Gupta, Sheila Webster, Tammy Degelder, Patricia Haines, Lee-Anne Stayner, Shauna McGill, Lisa Wang, Richard Piekarz, Tracy Wong, Lillian L. Siu, Igor Espinoza-Delgado, Julianne L. Holleran, Merrill J. Egorin & Karen W. L. Yee. (2015) A phase I trial of two sequence-specific schedules of decitabine and vorinostat in patients with acute myeloid leukemia. Leukemia & Lymphoma 56:10, pages 2793-2802.
Read now
Read now
Annette Romanski, Kerstin Schwarz, Maren Keller, Sarah Wietbrauk, Anja Vogel, Jessica Roos, Claudia Oancea, Boris Brill, Oliver H. Krämer, Hubert Serve, Martin Ruthardt & Gesine Bug. (2012) Deacetylase inhibitors modulate proliferation and self-renewal properties of leukemic stem and progenitor cells. Cell Cycle 11:17, pages 3219-3226.
Read now
Read now
Articles from other publishers (65)
Ritwick Sawarkar. 2023. Chaperones. Chaperones
61
71
.
Anneke D. van Dijk, Ti’ara L. Griffen, Yihua H. Qiu, Fieke W. Hoff, Endurance Toro, Kevin Ruiz, Peter P. Ruvolo, James W. LillardJrJr, Eveline S. J. M. de Bont, Jan A. Burger, William Wierda & Steven M. Kornblau. (2021) RPPA-based proteomics recognizes distinct epigenetic signatures in chronic lymphocytic leukemia with clinical consequences. Leukemia 36:3, pages 712-722.
Crossref
Crossref
Suleyman Vural, Alida Palmisano, William C. Reinhold, Yves Pommier, Beverly A. Teicher & Julia Krushkal. (2021) Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines. Clinical Epigenetics 13:1.
Crossref
Crossref
Xuejie Jiang, Ling Jiang, Jiaying Cheng, Fang Chen, Jinle Ni, Changxin Yin, Qiang Wang, Zhixiang Wang, Dan Fang, Zhengshan Yi, Guopan Yu, Qingxiu Zhong, Bing Z. Carter & Fanyi Meng. (2021) Inhibition of EZH2 by chidamide exerts antileukemia activity and increases chemosensitivity through Smo/Gli-1 pathway in acute myeloid leukemia. Journal of Translational Medicine 19:1.
Crossref
Crossref
Song-Hee Kim, Byung-Chul Kang, Daseul Seong, Won-Hyeok Lee, Jae-Hee An, Hyoung-Uk Je, Hee-Jeong Cha, Hyo-Won Chang, Sang-Yoon Kim, Seong-Who Kim & Myung-Woul Han. (2021) EPHA3 Contributes to Epigenetic Suppression of PTEN in Radioresistant Head and Neck Cancer. Biomolecules 11:4, pages 599.
Crossref
Crossref
Rhian Jones, Susanne Wijesinghe, Claire Wilson, John Halsall, Triantafillos Liloglou & Aditi Kanhere. (2021) A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1. iScience 24:4, pages 102273.
Crossref
Crossref
Li-Peng Hu, Kai-Xia Zhou, Yan-Miao Huo, De-Jun Liu, Qing Li, Min-Wei Yang, Pei-Qi Huang, Chun-Jie Xu, Guang-Ang Tian, Lin-Li Yao, Xue-Li Zhang, Ya-Hui Wang, Jun Li, Zhi-Gang Zhang, Shu-Heng Jiang, Xin Xing, Xu Wang, Wei-Ting Qin & Qin Yang. (2021) Single-cell RNA sequencing reveals that targeting HSP90 suppresses PDAC progression by restraining mitochondrial bioenergetics. Oncogenesis 10:3.
Crossref
Crossref
Saimul Islam, Hemantika Dasgupta, Mukta Basu, Anup Roy, Neyaz Alam, Susanta Roychoudhury & Chinmay Kumar Panda. (2020) Downregulation of beta-catenin in chemo-tolerant TNBC through changes in receptor and antagonist profiles of the WNT pathway: Clinical and prognostic implications. Cellular Oncology 43:4, pages 725-741.
Crossref
Crossref
Mariusz L. Hartman, Magdalena Rogut, Aleksandra Mielczarek-Lewandowska, Michal Wozniak & Malgorzata Czyz. (2020) 17-Aminogeldanamycin Inhibits Constitutive Nuclear Factor-Kappa B (NF-κB) Activity in Patient-Derived Melanoma Cell Lines. International Journal of Molecular Sciences 21:11, pages 3749.
Crossref
Crossref
Darren PanRaajit Rampal & John Mascarenhas. (2020) Clinical developments in epigenetic-directed therapies in acute myeloid leukemia. Blood Advances 4:5, pages 970-982.
Crossref
Crossref
San José-Enériz, Gimenez-Camino, Agirre & Prosper. (2019) HDAC Inhibitors in Acute Myeloid Leukemia. Cancers 11:11, pages 1794.
Crossref
Crossref
Jun-Cheng Guo, Yi-Jun Yang, Jin-Fang Zheng, Jian-Quan Zhang, Min Guo, Xiang Yang, Xiang-Ling Jiang, Li Xiang, You Li, Huang Ping & Liu Zhuo. (2019) Silencing of long noncoding RNA HOXA11-AS inhibits the Wnt signaling pathway via the upregulation of HOXA11 and thereby inhibits the proliferation, invasion, and self-renewal of hepatocellular carcinoma stem cells. Experimental & Molecular Medicine 51:11, pages 1-20.
Crossref
Crossref
Bumjun Kim, Caroline D. Pena & Debra T. Auguste. (2019)
Targeted Lipid Nanoemulsions Encapsulating Epigenetic Drugs Exhibit Selective Cytotoxicity on CDH1
–
/FOXM1
+
Triple Negative Breast Cancer Cells
. Molecular Pharmaceutics 16:5, pages 1813-1826.
Crossref
Crossref
Jan Philipp Bewersdorf, Rory Shallis, Maximilian Stahl & Amer M. Zeidan. (2019) Epigenetic therapy combinations in acute myeloid leukemia: what are the options?. Therapeutic Advances in Hematology 10, pages 204062071881669.
Crossref
Crossref
Johanna Ungerstedt. (2018) Epigenetic Modifiers in Myeloid Malignancies: The Role of Histone Deacetylase Inhibitors. International Journal of Molecular Sciences 19:10, pages 3091.
Crossref
Crossref
Aneliya Yoveva & Ritwick Sawarkar. 2018. Chaperones. Chaperones
221
231
.
G Garcia-Manero, M A Sekeres, M Egyed, M Breccia, C Graux, J D Cavenagh, H Salman, A Illes, P Fenaux, D J DeAngelo, R Stauder, K Yee, N Zhu, J-H Lee, D Valcarcel, A MacWhannell, Z Borbenyi, L Gazi, S Acharyya, S Ide, M Marker & O G Ottmann. (2017) A phase 1b/2b multicenter study of oral panobinostat plus azacitidine in adults with MDS, CMML or AML with ⩽30% blasts. Leukemia 31:12, pages 2799-2806.
Crossref
Crossref
SongTao Xiang, PeiLiang Zou, Qing Tang, Fang Zheng, JingJing Wu, ZhiQiang Chen & Swei Sunny Hann. (2017) HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo. Biochimica et Biophysica Acta (BBA) - General Subjects.
Crossref
Crossref
Chana L. Glasser, Alice Lee, Don Eslin, Lianna Marks, Shakeel Modak & Julia L. Glade Bender. (2017) Epigenetic Combination Therapy for Children With Secondary Myelodysplastic Syndrome (MDS)/Acute Myeloid Leukemia (AML) and Concurrent Solid Tumor Relapse. Journal of Pediatric Hematology/Oncology 39:7, pages 560-564.
Crossref
Crossref
Elodie M. Da Costa, Gabrielle McInnes, Annie Beaudry & Noël J.-M. Raynal. (2017) DNA Methylation–Targeted Drugs. The Cancer Journal 23:5, pages 270-276.
Crossref
Crossref
JingJing Wu, Qing Tang, LiJuan Yang, YuQing Chen, Fang Zheng & Swei Sunny Hann. (2017) Interplay of DNA methyltransferase 1 and EZH2 through inactivation of Stat3 contributes to β-elemene-inhibited growth of nasopharyngeal carcinoma cells. Scientific Reports 7:1.
Crossref
Crossref
Chengyin Min, Nathan Moore, Jeffrey R. Shearstone, Steven N. Quayle, Pengyu Huang, John H. van Duzer, Matthew B. Jarpe, Simon S. Jones & Min Yang. (2017) Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia. PLOS ONE 12:1, pages e0169128.
Crossref
Crossref
Hsiang-Hsi Ling, Chih-Chia Kuo, Bo-Xing Lin, Yen-Hua Huang & Cheng-Wei Lin. (2017) Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer. Experimental Cell Research 350:1, pages 218-225.
Crossref
Crossref
Longmei Li, JingJing Wu, Fang Zheng, Qing Tang, WanYin Wu & Swei Sunny Hann. (2016) Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I. Journal of Experimental & Clinical Cancer Research 35:1.
Crossref
Crossref
Andrew J. Wilson, Kofi Sarfo-Kantanka, Toby Barrack, Alexandra Steck, Jeanette Saskowski, Marta A. Crispens & Dineo Khabele. (2016) Panobinostat sensitizes cyclin E high, homologous recombination-proficient ovarian cancer to olaparib. Gynecologic Oncology 143:1, pages 143-151.
Crossref
Crossref
Sophie Bouchat, Nadège Delacourt, Anna Kula, Gilles Darcis, Benoit Van Driessche, Francis Corazza, Jean‐Stéphane Gatot, Adeline Melard, Caroline Vanhulle, Kabamba Kabeya, Marion Pardons, Véronique Avettand‐Fenoel, Nathan Clumeck, Stéphane De Wit, Olivier Rohr, Christine Rouzioux & Carine Van Lint. (2015)
Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates
HIV
‐1
. EMBO Molecular Medicine 8:2, pages 117-138.
Crossref
Crossref
Jennifer S. Isaacs. 2016. Hsp90 in Cancer: Beyond the Usual Suspects. Hsp90 in Cancer: Beyond the Usual Suspects
107
140
.
Noël J.-M. Raynal. 2016. Drug Discovery in Cancer Epigenetics. Drug Discovery in Cancer Epigenetics
347
371
.
Jingjing Wu, Shunyu Zhao, Qing Tang, Fang Zheng, YuQin Chen, LiJun Yang, Xiaobing Yang, Liuning Li, WanYin Wu & Swei Sunny Hann. (2015) Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells. Journal of Experimental & Clinical Cancer Research 34:1.
Crossref
Crossref
Narsimha Reddy Penthala, Amit Ketkar, Konjeti R. Sekhar, Michael L. Freeman, Robert L. Eoff, Ramesh Balusu & Peter A. Crooks. (2015) 1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1). Bioorganic & Medicinal Chemistry 23:22, pages 7226-7233.
Crossref
Crossref
Kayo Harada-Shirado, Kazuhiko Ikeda, Kazuei Ogawa, Hiroshi Ohkawara, Hideo Kimura, Tatsuyuki Kai, Hideyoshi Noji, Soji Morishita, Norio Komatsu & Yasuchika Takeishi. (2015)
Dysregulation of the
MIRLET7
/
HMGA2
axis with methylation of the
CDKN2A
promoter in myeloproliferative neoplasms
. British Journal of Haematology 168:3, pages 338-349.
Crossref
Crossref
Keqin Kathy Li, Kenneth Huang, Shukkoor Kondengaden, Jonathan Wooten, Hamed Reyhanfard, Zhang Qing, Bingxue Chris Zhai & Peng George Wang. 2015. Epigenetic Technological Applications. Epigenetic Technological Applications
363
395
.
Ramesh Balusu, Warren Fiskus & Kapil N. Bhalla. 2015. Targeted Therapy of Acute Myeloid Leukemia. Targeted Therapy of Acute Myeloid Leukemia
251
273
.
Mark Kirschbaum, Ivana Gojo, Stuart L. Goldberg, Christopher Bredeson, Lisa A. Kujawski, Allen Yang, Peter Marks, Paul Frankel, Xing Sun, Alessandra Tosolini, Joseph E. Eid, Gregory M. Lubiniecki & Jean-Pierre Issa. (2014) A phase 1 clinical trial of vorinostat in combination with decitabine in patients with acute myeloid leukaemia or myelodysplastic syndrome. British Journal of Haematology 167:2, pages 185-193.
Crossref
Crossref
James Smadbeck, Meghan B. Peterson, Barry M. Zee, Shivani Garapaty, Aashna Mago, Christina Lee, Athanassios Giannis, Patrick Trojer, Benjamin A. Garcia & Christodoulos A. Floudas. (2014) De Novo Peptide Design and Experimental Validation of Histone Methyltransferase Inhibitors. PLoS ONE 9:2, pages e90095.
Crossref
Crossref
Alison Urvalek, Kristian Bruun Laursen & Lorraine J. Gudas. 2014. The Biochemistry of Retinoic Acid Receptors I: Structure, Activation, and Function at the Molecular Level. The Biochemistry of Retinoic Acid Receptors I: Structure, Activation, and Function at the Molecular Level
129
149
.
Björn Hackanson & Michael Daskalakis. 2014. Small Molecules in Oncology. Small Molecules in Oncology
269
297
.
Daniel J. DeAngelo, Ruben A. Mesa, Warren Fiskus, Ayalew Tefferi, Carole Paley, Martha Wadleigh, Ellen K. Ritchie, David S. Snyder, Kebede Begna, Siddhartha Ganguly, Michael S. Ondovik, Jessica Rine & Kapil N. Bhalla. (2013) Phase II trial of panobinostat, an oral pan-deacetylase inhibitor in patients with primary myelofibrosis, post-essential thrombocythaemia, and post-polycythaemia vera myelofibrosis. British Journal of Haematology 162:3, pages 326-335.
Crossref
Crossref
D J DeAngelo, A Spencer, K N Bhalla, H M Prince, T Fischer, T Kindler, F J Giles, J W Scott, K Parker, A Liu, M Woo, P Atadja, K K Mishra & O G Ottmann. (2013) Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies. Leukemia 27:8, pages 1628-1636.
Crossref
Crossref
Jianbiao Zhou & Wee-Joo Chng. (2013) Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer. Mitochondrion 13:3, pages 163-169.
Crossref
Crossref
Elisabeth J. Walsby, Michelle Lazenby, Chris J. Pepper, Steven Knapper & Alan K. Burnett. (2013)
The
HSP
90 inhibitor
NVP
‐
AUY
922‐
AG
inhibits the
PI
3K and
IKK
signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells
. British Journal of Haematology 161:1, pages 57-67.
Crossref
Crossref
Monica L. Guzman, Maeve A. Lowery, Tony Taldone, John KorenIIIIII, Erica DaGama Gomes & Gabriela Chiosis. 2013. Cell Death Signaling in Cancer Biology and Treatment. Cell Death Signaling in Cancer Biology and Treatment
181
203
.
Elke De Bruyne, Ken Maes, Sarah Deleu, Els Van Valckenborgh, Eline Menu, Isabelle Vande Broek, Joanna Fraczek, Leo van Grunsven, Vera Rogiers, Helena Jernberg-Wiklund & Karin Vanderkerken. 2013. Advances in Biology and Therapy of Multiple Myeloma. Advances in Biology and Therapy of Multiple Myeloma
255
282
.
Steffen Zopf, Matthias Ocker, Daniel Neureiter, Beate Alinger, Susanne Gahr, Markus F Neurath & Pietro Di Fazio. (2012) Inhibition of DNA methyltransferase activity and expression by treatment with the pan-deacetylase inhibitor panobinostat in hepatocellular carcinoma cell lines. BMC Cancer 12:1.
Crossref
Crossref
Francesco Crea, Lorenzo Fornaro, Guido Bocci, Lei Sun, William L. Farrar, Alfredo Falcone & Romano Danesi. (2012) EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis. Cancer and Metastasis Reviews 31:3-4, pages 753-761.
Crossref
Crossref
Warren Fiskus, Rekha Rao, Ramesh Balusu, Siddhartha Ganguly, Jianguo Tao, Eduardo Sotomayor, Uma Mudunuru, Jacqueline E. Smith, Stacey L. Hembruff, Peter Atadja, Victor E. Marquez & Kapil Bhalla. (2012) Superior Efficacy of a Combined Epigenetic Therapy against Human Mantle Cell Lymphoma Cells. Clinical Cancer Research 18:22, pages 6227-6238.
Crossref
Crossref
Jurate Savickiene, Grazina Treigyte, Arune Jazdauskaite, Veronika‐Viktorija Borutinskaite & Ruta Navakauskiene. (2013) DNA methyltransferase inhibitor RG108 and histone deacetylase inhibitors cooperate to enhance NB4 cell differentiation and E‐cadherin re‐expression by chromatin remodelling. Cell Biology International 36:11, pages 1067-1078.
Crossref
Crossref
Warren Fiskus, Siddhartha Ganguly, Suman Kambhampati & Kapil N. Bhalla. (2012) Role of Additional Novel Therapies in Myeloproliferative Neoplasms. Hematology/Oncology Clinics of North America 26:5, pages 959-980.
Crossref
Crossref
Tareq Al Baghdadi, Rafat Abonour & H. Scott Boswell. (2012) Novel Combination Treatments Targeting Chronic Myeloid Leukemia Stem Cells. Clinical Lymphoma Myeloma and Leukemia 12:2, pages 94-105.
Crossref
Crossref
F Cherblanc, N Chapman-Rothe, R BrownMJ Fuchter. (2012) Current limitations and future opportunities for epigenetic therapies. Future Medicinal Chemistry 4:4, pages 425-446.
Crossref
Crossref
Roberta Ciarapica, Lucio Miele, Antonio Giordano, Franco Locatelli & Rossella Rota. (2011) Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications. BMC Medicine 9:1.
Crossref
Crossref
Ramesh BalusuWarren FiskusRekha RaoDaniel G. ChongSrilatha NalluriUma MudunuruHongwei MaLei ChenSreedhar VenkannagariKyungsoo HaSunil AbhyankarCasey WilliamsJoseph McGuirkHanna Jean Khoury, Celalettin Ustun & Kapil N. Bhalla. (2011) Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1. Blood 118:11, pages 3096-3106.
Crossref
Crossref
Alessandro Allegra, Emanuela Sant’Antonio, Giuseppa Penna, Andrea Alonci, Arianna D’Angelo, Sabina Russo, Antonino Cannavò, Demetrio Gerace & Caterina Musolino. (2011) Novel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors. European Journal of Haematology 86:2, pages 93-110.
Crossref
Crossref
Mi Jeong Kwon & Young Kee Shin. (2011) Epigenetic Regulation of Cancer-Associated Genes in Ovarian Cancer. International Journal of Molecular Sciences 12:2, pages 983-1008.
Crossref
Crossref
Harrison W. Lin & James W. Rocco. 2011. Signaling Pathways in Squamous Cancer. Signaling Pathways in Squamous Cancer
365
382
.
Aditya MandawatWarren FiskusKathleen M. BuckleyKelly RobbinsRekha RaoRamesh BalusuJean-Marc NavenotZi-Xuan WangCelalettin UstunDaniel G. ChongPeter Atadja, Nobutaka Fujii, Stephen C. PeiperKapil Bhalla. (2010) Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists. Blood 116:24, pages 5306-5315.
Crossref
Crossref
Gesine Bug & Oliver G. Ottmann. (2010) The DAC system and associations with acute leukemias and myelodysplastic syndromes. Investigational New Drugs 28:S1, pages 36-49.
Crossref
Crossref
Rekha Rao, Srilatha Nalluri, Warren Fiskus, Ramesh Balusu, Atul Joshi, Uma Mudunuru, Kathleen M. Buckley, Kelly Robbins, Celalettin Ustun, Gary W. Reuther & Kapil N. Bhalla. (2010) Heat Shock Protein 90 Inhibition Depletes TrkA Levels and Signaling in Human Acute Leukemia Cells. Molecular Cancer Therapeutics 9:8, pages 2232-2242.
Crossref
Crossref
Amal J. Johnston, Olga Kirioukhova, Philippa J. Barrell, Twan Rutten, James M. Moore, Ramamurthy Baskar, Ueli Grossniklaus & Wilhelm Gruissem. (2010) Dosage-Sensitive Function of RETINOBLASTOMA RELATED and Convergent Epigenetic Control Are Required during the Arabidopsis Life Cycle. PLoS Genetics 6:6, pages e1000988.
Crossref
Crossref
Rekha Rao, Srilatha Nalluri, Ravindra Kolhe, Yonghua Yang, Warren Fiskus, Jianguang Chen, Kyungsoo Ha, Kathleen M. Buckley, Ramesh Balusu, Veena Coothankandaswamy, Atul Joshi, Peter Atadja & Kapil N. Bhalla. (2010) Treatment with Panobinostat Induces Glucose-Regulated Protein 78 Acetylation and Endoplasmic Reticulum Stress in Breast Cancer Cells. Molecular Cancer Therapeutics 9:4, pages 942-952.
Crossref
Crossref
Michael Daskalakis, Nadja Blagitko-Dorfs & Björn Hackanson. 2010. Small Molecules in Oncology. Small Molecules in Oncology
131
157
.
Yongchao WangWarren FiskusDaniel G. ChongKathleen M. BuckleyKavita NatarajanRekha RaoAtul JoshiRamesh BalusuSanjay KoulJianguang ChenAndrew SavoieCelalettin UstunAnand P. JillellaPeter Atadja, Ross L. Levine & Kapil N. Bhalla. (2009) Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells. Blood 114:24, pages 5024-5033.
Crossref
Crossref
Keith D. Robertson & Kapil N. Bhalla. (2009) Missteps in “tango” for epigenome targeting. Blood 114:13, pages 2569-2570.
Crossref
Crossref
Warren FiskusYongchao WangArun SreekumarKathleen M. BuckleyHuidong ShiAnand JillellaCelalettin UstunRekha RaoPravina FernandezJianguang ChenRamesh BalusuSanjay KoulPeter Atadja, Victor E. Marquez & Kapil N. Bhalla. (2009) Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells. Blood 114:13, pages 2733-2743.
Crossref
Crossref
Robert A. Copeland, Michael E. Solomon & Victoria M. Richon. (2009) Protein methyltransferases as a target class for drug discovery. Nature Reviews Drug Discovery 8:9, pages 724-732.
Crossref
Crossref